© Judith Stepper

Below you can find publications of work that has been carried out within the Research Training Group Chembion.

  • 2022

    • H. Huang, P. Bellotti, J. Erchinger, T. O. Paulisch, F. Glorius,* Radical Carbonyl Umpolung Arylation via Dual Catalysis, J. Am. Chem. Soc. 2022, 144, 1899–1909. Link to Huang et al., 2022
  • 2021

    • Cerina M., Fazio L., Meuth S.G. (2021) Electrophysiological Measurements for Brain Network Characterisation in Rodents. In: Groppa S., G. Meuth S. (eds) Translational Methods for Multiple Sclerosis Research. Neuromethods vol 166. Humana, New York, Ny. Link to Cerina et al., 2021

    • Chamlali M, Kouba S, Rodat-Despoix L, Todesca LM, Pethö Z, Schwab A, Ouadid-Ahidouch H.  Orai3 Calcium Channel Regulates Breast Cancer Cell Migration through Calcium-Dependent and -Independent Mechanisms.  Cells. (2021)  Link to Chamlali et al. 2021 

    • Tobias Ruck, Stefanie Bock, Steffen Pfeuffer, Christina B. Schroeter, Derya Cengiz, Paul Marciniak, Maren Lindner, Alexander Herrmann, Marie Liebmann, Stjepana Kovac, Lukas Gola, Leoni Rolfes, Marc Pawlitzki, Nils Opel, Tim Hahn, Udo Dannlowski, Thomas Pap, Felix Luessi, Julian A. Schreiber, Bernhard Wünsch, Tanja Kuhlmann, Guiscard Seebohm, Björn Tackenberg, Patricia Seja, Frank Döring, Erhard Wischmeyer, Achmet Imam Chasan, Johannes Roth, Luisa Klotz, Gerd Meyer zu Hörste, Heinz Wiendl, Tobias Marschall, Stefan Floess, Jochen Huehn, Thomas Budde, Tobias Bopp, Stefan Bittner & Sven G. Meuth  K2P18.1 translates T cell receptor signals into thymic regulatory T cell development  Cell Research (2021) Link to Ruck et al., 2021

    • Remya Rajan, Dirk Schepmann, Ruben Steigerwald, Julian A Schreiber, Ehab El-Awaad, Joachim Jose, Guiscard Seebohm, Bernhard Wünsch  [2.2]Paracyclophane-Based TCN-201 Analogs as GluN2A-Selective NMDA Receptor Antagonists  ChemMedChem (2021) Link to Rajan et al., 2021

    • Anne Gresch, Héctor Noguera Hurtado, Laura Wörmeyer, Vivien De Luca, Rebekka Wiggers, Guiscard Seebohm, Bernhard Wünsch and Martina Düfer  Selective Inhibition of NMDA receptors with GluN2B subunit protects beta cells against stress-induced apoptotic cell death J Pharmacol Exp Ther (2021)  Link to Gresch et al., 2021

    • Kathrin Brömmel, Christian Paul Konken, Frederik Borgel, Henry Obeng-Darko, Sonja Schelhaas, Etmar Bulk, Thomas Budde, Albrecht Schwab, Michael Schafers and Bernhard Wunsch  Synthesis and biological evaluation of PET tracers designed for imaging of calcium activated potassium channel 3.1 (KCa3.1) channels in vivo  RSC Advances (2021) Link to Brömmel et al., 2021

    • Vinnenberg L, Bock S, Hundehege P, Ruck T, Meuth SG. Impact of Diverse Ion Channels on Regulatory T Cell Functions  Cell Physiol Biochem (2021) Link to Vinnenberg et al. 2021

    • Luca Matteo Todesca, Sarah Maskri, Kathrin Brömmel, Insa Thale, Bernhard Wünsch, Oliver Koch, Albrecht Schwab.  Targeting K ca 3.1 Channels in Cancer Cell Physiol Biochem (2021)  Link to Todesca et al. 2021

    • Menke, J., Maskri, S. and Koch, O.  Computational Ion Channel Research: from the Application of Artificial Intelligence to Molecular Dynamics Simulations  Cell Physiol Biochem (2021) Link to Menke et al. 2021

    • Menke, J., Koch, O.  Using Domain-Specific Fingerprints Generated Through Neural Networks to Enhance Ligand-based Virtual Screening  J. Chem. Inf. Model. (2021) Link to Menke & Koch 2021

    • Elena Bechthold, Julian A. Schreiber, Kirstin Lehmkuhl, Bastian Frehland, Dirk Schepmann, Freddy A. Bernal, Constantin Daniliuc, Inés Álvarez, Cristina Val Garcia, Thomas J. Schmidt, Guiscard Seebohm, and Bernhard Wünsch  Ifenprodil Stereoisomers: Synthesis, Absolute Configuration, and Correlation with Biological Activity  J. Med. Chem. (2021)  Link to Bechthold et al. 2021

    • Nadine Ritter, Marvin Korff, Alexander Markus, Dirk Schepmann, Guiscard Seebohm, Julian A. Schreiber, Bernhard Wünsch  Deconstruction – Reconstruction: Analysis of the Crucial Structural Elements of GluN2B-Selective, Negative Allosteric NMDA Receptor Modulators with
      3-Benzazepine Scaffold  Cell Physiol Biochem (2021) Link to Ritter et al. 2021

    • Hofschröer V, Najder K, Rugi M, Bouazzi R, Cozzolino M, Arcangeli A, Panyi G, Schwab A.  Ion Channels Orchestrate Pancreatic Ductal Adenocarcinoma Progression and Therapy.  Front Pharmacol. (2021) Link to Hofschröer et al. 2021

    • T.O. Paulisch,§ L. Mai,§ F. Strieth-Kalthoff,§ M.J. James, C. Henkel, D.M. Guldi,* F. Glorius, * Dynamic Kinetic Sensitization of β-Dicarbonyl Compounds—Access to Medium-Sized Rings by De Mayo-Type Ring Expansion, Angew. Chem. Int. Ed. 2021, e202112695; Angew. Chem. 2021, e202112695. Link to Paulisch et al., 2021

    • H. Wang, P. Bellotti, X. Zhang, T. O. Paulisch, F. Glorius,* A base-controlled switch of SO2 reincorporation in photocatalyzed radical difunctionalization of alkenes, Chem 2021, 7, 3412–3424. Link to Wang et al., 2021

    • S. Kriegler, T. O Paulisch, T. Wegner, F. Glorius,* R. Winter,* Bipolar Imidazolium-Based Lipid Analogues for Artificial Archaeosomes, Langmuir 2021, 37, 11996–12006. Link to Kriegler et al., 2021

    • J.-H. Ye, P. Bellotti, T. O. Paulisch, C. G. Daniliuc, F. Glorius,* Visible-Light-Induced Cycloaddition of α-Ketoacylsilanes with Imines: Facile Access to β-Lactams, Angew. Chem. Int. Ed. 2021, 60, 13671-13676; Angew. Chem. 2021, 133, 13785–13790. Link to Ye et al., 2021


  • 2020

    • Kathrin Brömmel, Sarah Maskri, Etmar Bulk, Zoltan Pethő, Marius Rieke, Thomas Budde, Oliver Koch, Albrecht Schwab, Bernhard Wünsch  Co-staining of KCa3.1 Channels in NSCLC Cells with a SmallMolecule Fluorescent Probe and Antibody-Based Indirect Immunofluorescence. ChemMedChem (2020) Link to Brömmel et al. 2020

    • Wang T, Young S, Krenz H, Tüttelmann F, Röpke A, Krallmann C, Kliesch S, Zeng XH, Brenker C, Strünker T.  The Ca2+ channel CatSper is not activated by cAMP/PKA signaling but directly affected by chemicals used to probe the action of cAMP and PKA.  Journal of Biological Chemistry (2020) Link to Wang et al. 2020

    • Schwab A, Loeck T, Najder-Nalepa K.  STIM2: Redox-sensor and effector of the (tumor) microenvironment. Cell Calcium. (2020) Link to Schwab et al. 2020

    • Anne Gresch, Martina Düfer  Dextromethorphan and Dextrorphan influence insulin secretion by interacting with KATP and L-type Ca2+ channels in pancreatic beta cells, J Pharmacol Exp Ther (2020) Link to Gresch & Düfer 2020

    • Pethő Z, Najder K, Carvalho T, McMorrow R, Todesca LM, Rugi M, Bulk E, Chan A, Löwik CWGM, Reshkin SJ, Schwab A.    pH-Channeling in Cancer: How pH-Dependence of Cation Channels Shapes Cancer Pathophysiology. Cancers (2020) Link to Pethő et al. 2020

    • Etmar Bulk, Luca Matteo Todesca, Albrecht Schwab.   Ion Channels in Lung Cancer
      Rev Physiol Biochem Pharmacol. (2020) Link to Bulk et al. 2020

    • Brömmel K, Maskri S, Maisuls I, Konken C P, Rieke M, Pethő Z, Strassert C A, Koch O, Schwab A, Wünsch B.   Synthesis of Small-Molecule Fluorescent Probes for the In Vitro Imaging of Calcium‐Activated Potassium Channel KCa3.1 Angewandte Chemie (2020) Link to Brömmel et al. 2020

    • Eva Bollmann, Julian Alexander Schreiber, Nadine Ritter, Stefan Peischard, Huyen Tran Ho, Bernhard Wünsch, Timo Strünker, Sven Meuth, Thomas Budde, Nathalie Strutz-Seebohm, Guiscard Seebohm  4,4'-Diisothiocyanato-2,2'-Stilbenedisulfonic Acid (DIDS) Modulates the Activity of KCNQ1/KCNE1 Channels by an Interaction with the Central Pore Region. Cell Physiol Biochem (2020) Link to Bollmann et al., 2020

    • T. O. Paulisch, S. Bornemann, M. Herzog, S. Kudruk, L. Roling, A. L. Linard Matos, H.-J. Galla, V. Gerke,* R. Winter,* F. Glorius,* An Imidazolium‐based Lipid Analogue as Gene Transfer Agent, Chem. Eur. J. 2020, 26, 17176–17182. Link to Paulisch et al., 2020

    • S. Bornemann, M. Herzog, L. Roling, T. O. Paulisch, D. Brandis, S. Kriegler, H.-J. Galla, F. Glorius,* R. Winter,* lnteraction of imidazolium-based lipids with phospholipid bilayer membranes of different complexity, Phys. Chem. Chem. Phys. 2020, 22, 9775–9788. Link to Bornemann et al., 2020

    • J. L. Schwarz, R. Kleinmans, T. O. Paulisch, F. Glorius,* 1,2-Amino Alcohols via Cr/Photoredox Dual-Catalyzed Addition of α‑Amino Carbanion Equivalents to Carbonyls, J. Am. Chem. Soc. 2020, 142, 2168–2174. Link to Schwarz et al., 2020

    • Kuntze A, Goetsch O, Fels B, Najder K, Unger A, Wilhelmi M, Sargin S, Schimmelpfennig S, Neumann I, Schwab A, Pethő Z.   Protonation of Piezo1 Impairs Cell-Matrix Interactions of Pancreatic Stellate Cells. Front. Physiol. (2020) Link to Kuntze et al. 2020



    Other publications

    • Schierling T., Strünker T., Wünsch B  Synthesis of caged prostaglandin E1 derivatives to study the
      ligand-control of CatSper Ca2+ channels 

    12th International/11th European/ 32nd German Congress of Andrology, Münster 2020
    J. Reproduct. Med. Endocrinol. (2020), 17 (Supplementum 1), 83.

    • T. Depmeier, T. Strünker, M. Lehr, J. Fabian, T. Philipps  Action of progesterone on 2-arachidonoylglycerol (2-AG) levels and enzymes metabolizing 2-AG in human sperm 

    12th International/11th European/ 32nd German Congress of Andrology, Münster 2020
    J. Reproduct. Med. Endocrinol. (2020), 17 (Supplementum 1), 44.


  • 2019

    • Schreiber, J.A., Schepmann, D., Frehland, B., Thum, S., Datunashvili, M., Budde, T., Hollmann, M., Strutz-Seebohm, N., Wünsch, B. & Seebohm, G.    A common mechanism allows selective targeting of GluN2B subunit-containing N-methyl-D-aspartate receptors. Commun Biol 2, 420 (2019) Link to Schreiber et al. 2019