Molekulare Psychiatrie

Gegenstand der Forschungen sind die genomische und funktionelle Charakterisierung von Prädispositionsgenen für neuropsychiatrische Erkrankungen, insbesondere Untersuchungen zu den molekularen Grundlagen von Angsterkrankungen.

Drittmittelgeber:

Deutsche Forschungsgemeinschaft

Beteiligte Wissenschaftler:

Priv.-Doz. Dr. Jürgen Deckert (Leiter), Prof. Dr. V. Arolt, Dr. P. Pecuch, Prof. Dr. M.M. Nöthen, Prof. Dr. P. Propping, Prof. Dr. W. Maier

Veröffentlichungen:

Arolt, V., R. Lencer, A. Nolte, B. Müller-Myhsok, S. Purmann, M. Schürmann, J. Leutelt, M. Pinnow, E. Schwinger: Eye Tracking Dysfunction is a putative phenotypic susceptibility marker of schizophrenia and maps to a locus on chromosome 6p in families with multiple occurrence of the disease. American Journal of Medical Genetics 67, 564-579, 1996

Arolt, V., R. Lencer, S. Purmann, M. Schürmann, K. Krecker, E. Schwinger: Testing for Linkage of Eye Tracking Dysfunction and Schizophrenia to Markers on Chromosome 6, 8, 9, 20 and 22 in Families Multiply Affected with Schoziphrenia. American Journal of Medical Genetics, im Druck

Deckert, J., M. Catalano, A. Heils, D. DiBella, F. Friess, E. Politi, P. Franke, M.M. Nöthen, W. Maier, L. Bellodi, K.P. Lesch: Functional promoter polymorphism of the human serotonin transporter: Lack of association with panic disorder, Psychiatric Genetics 7, 45-47, 1997

Deckert, J., M.M. Nöthen, P. Franke, C. Delmo, J. Fritze, M. Knapp, W. Maier, H. Beckmann, P. Propping: Systematic mutation screening and association study of the A1 and A2A adenosine receptor genes in panic disorder suggest a contribution of the A2A gene to the development of disease, Molecular Psychiatry 3, 81-85, 1998

Deckert, J., M. Catalano, J. Syagailo, M. Bosi, O. Okladnova, D. DiBella, M.M. Nöthen, P. Maffei, P. Franke, J. Fritze, W. Maier, P. Propping, H. Beckmann, L. Bellodi, K.P. Lesch: Excess of high activity monoamineoxidase A gene promoter alleles in female patients with panic disorder. Human Molecular Genetics 8, 621-624, 1999