Allgemeines Physikalisches Kolloquium im Wintersemester 2008/2009

Ort:    48149 Münster, Wilhelm-Klemm-Str. 10, IG I, HS 2,
Zeit:    Donnerstag, 27.11.2008 16:00 Uhr c.t.
Kolloquiums-Kaffee ab 15:45 Uhr vor dem Hörsaal

NanoBiophysics: Mechanisms of Regulated Interaction, Switching and Control at the Single Molecule Level
Prof. Dr. D. Anselmetti, Experimentelle Biophysik und Angewandte Nanowissenschaften,
Universität Bielefeld

In nanobiophysical interaction analysis cellular processes can quantitatively be investigated with single molecular sensitivity that allow identification and quantification of molecular mechansims and analysis of individual biomolecules and cells with respect of protein structure, function and temporal dynamics. Nanobiophysical applications of atomic force microscopy and optical tweezers render information of the biomolecular regulatory mechanisms involved, and stimulate novel concepts for a reverse engineering of artificial molecular systems that can be affinity tuned, switched and controlled. In micro- and nanofluidics the migration dynamics of macromolecules and colloids in stuctured microchannels can be analyzed from a theoretical and experimental point of view. Especially, the consideration of dynamic effects far from thermal equilibrium gives insights and access to novel and sometimes paradox and unexpected phenomena. I will present recent results and applications that can be described within the theoretical frameworks of absolute negative particle mobility, dielectrophoresis, and ratcheting.