© Green Chameleon / Unsplash
  • 2024

    • Kreling V, Falcone FH, Herrmann F, Kemper L, Amiteye D, Cord-Landwehr S, Kehrenberg C, Moerschbacher BM, Hensel A (2024) High molecular / low acetylated chitosans reduce adhesion of Campylobacter jejuni to host cells by blocking JlpA. Applied Microbiology and Biotechnology. 108, 171. doi.org/10.1007/ss00253-024-13000-0.

    • Studt-Reinhold L, Atanasoff-Kardjalieff AK, Berger H, Petersen C, Bachleitner S, Sulyok M, Fischle A, Humpf H-U, Svetlana K, Teis Esben Søndergaard TE (2024) H3K27me3 is vital for fungal development and secondary metabolite gene silencing, and substitutes for the loss of H3K9me3 in the plant pathogen Fusarium proliferatum. PLOS Genetics 20(1): e1011075. doi.org/10.1371/journal.pgen.1011075.
  • 2023

    • Frutos-Grilo E, Kreling V, Hensel A, Campoy S (2023) Host-pathogen interaction: Enterobacter cloacae exerts different adhesion and invasion capacities against different host cell types. PlosOne 18(10): e0289334. https://doi.org/10.1371/journal.pone.0289334.

    • Jacobtorweihen J, Spiegler V (2023). Phylogenetic distribution of bromophenols in marine algae and the generation of a comprehensive bromophenol database. Phytochemistry Reviews 22, 505-542. doi: 10.1007/s11101-022-09847-8.

    • Jato J, Waindok P, Ngnodandi Belga F, Orman E, Agyare C, Oppong Bekoe E, Strube C, Hensel A, Liebau E, Spiegler V (2023) Anthelmintic activities of extract and ellagitannins from Phyllanthus urinaria L. against the model organism C. elegans and zoonotic or animal parasitic nematodes. Planta Medica 89, 1215-1228. doi 10.1055/a-2117-9426.

    • Kemper L, Hensel A (2023) Campylobacter jejuni: Targeting host cells, adhesion, invasion, survival. Applied Microbiology and Biotechnology. 107, 2725-2754. doi.org/10.1007/s00253-023-12456-w.

    • Mo B, Hensel A (2023) Alte Drogen - neue Erkenntnisse? Neue Strategien zur adjuvanten Behandlung von Harnwegsinfekten mit Schachtelhalmkraut. Zeitschrift für Phytotherapie. 44, 113-120. doi: 10.1055/a-1994-8808.

    • Mo B, Scharf B, Gutheil C, Letzel MC, Hensel A (2023) Tamm-Horsfall protein in humane urine: sex-dependent differences in the excretion and N-glycosylation pattern. Scientific Reports.13:17815. doi  0.1038/s41598-023-44650-1.

    • Orman E, Bekoe S, Asare-Nkansah S, Kralisch I, Jato J, Spiegler V, Agyare C, Oppong Bekoe E,
      Hensel A (2023) Analytical Method Development, Validation, and Quality Specifications for Combretum mucronatum Schumach & Thonn. Leaves, a West African traditional herbal remedy. Planta Medica 89, 860-878. doi 10.1055/a-2002-2260.

    • Orman E, Oppong Bekoe S, Asare-Nkansah S, Kralisch I, Jato J, Spiegler V, Agyare C, Oppong Bekoe E, Hensel A (2023) Towards the Development of Analytical Monograph Specifications for the Quality Assessment of the Medicinal Plant Phyllanthus urinaria. Phytochemistry, 113854. 14 pages doi.org/10.1016/j.phytochem.2023.113854.

    • Possart K, Herrmann FC, Jose J, Schmidt TJ (2023) In Silico and In Vitro Search for Dual Inhibitors of the Trypanosoma brucei and Leishmania major Pteridine Reductase 1 and Dihydrofolate Reductase. Molecules 2023, 28, 7526. DOI: 10.3390/molecules28227526.

    • Riekötter J, Oklestova J, Muth J, Twyman RM, Epping J (2023) Transcriptomic analysis of Chinese yam (Dioscorea polystachya Turcz.) variants indicates brassinosteroid involvement in tuber development. Front. Nutr. 10:1112793, doi: 10.3389/fnut.2023.1112793.

    • Suero Molina E, Black D, Walke A, Azemi G, d’Alessandro F, König S, Stummer W (2023) Unraveling the blue shift in porphyrin fluorescence in glioma: The 620 nm peak and its potential significance in tumor biology. Frontiers in Neuroscience 17:1261679, doi: 10.3389/fnins.2023.1261679.

    • Walke A, Black D, Valdes PA, Stummer W, König S, Suero-Molina E (2023) Challenges in, and recommendations for, hyperspectral imaging in ex vivo malignant glioma biopsy measurements. Scientific Reports 13: 3829, doi.org/10.1038/s41598-023-30680-2.

    • Walke A, Krone C, Stummer W, König S, Suero-Molina E (2023) Liquid biopsy in sera of high-grade glioma patients: Protoporphyrin IX allows discrimination from healthy controls in a proof-of-concept study. Scientific Reports, in revision.

    • Wolters SM, Benninghaus VA, Roelfs K-U, van Deenen N, Twyman RM, Prüfer D, Schulze Gronover C (2023) Overexpression of a pseudo-etiolated-in-light-like protein in Taraxacum koksaghyz leads to a pale green phenotype and enables transcriptome-based network analysis of photomorphogenesis and isoprenoid biosynthesis. Front. Plant Sci. 14:1228961, doi: 10.3389/fpls.2023.1228961.

    • Wunsch F, Nguyen T N, Wolber G, Bermudez M (2023) Structural determinants of sphingosine-1-phosphate receptor selectivity. Archiv der Pharmazie, 356:e2300387. doi 10.1002/ardp.202300387.

  • 2022

    • Atanasoff‐Kardjalieff AK, Seidl B, Steinert K, Daniliuc CG, Schuhmacher R, Humpf H-U, Kalinina S, Studt‐Reinhold L (2022) Biosynthesis of the Isocoumarin Derivatives Fusamarins Is Mediated by the PKS8 Gene Cluster in Fusarium. ChemBioChem 2022. https://doi.org/10.1002/cbic.202200342.

    • Classen N, Ulrich D, Hofemeier A, Hennies MT, Hafezi W, Pettke A, Romberg ML, Lorentzen EU, Hensel A, Kühn JE (2022) Broadly Applicable, Virus-Free Dual Reporter Assay to Identify Compounds Interfering with Membrane Fusion: Performance for HSV-1 and SARS-CoV-2. Viruses. 2022 Jun 21;14(7):1354. doi: 10.3390/v14071354.

    • Ernst S, Volkov AN, Stark M, Hölscher L, Steinert K, Fetzner S, Hennecke U, Drees SL (2022) Azetidomonamide and Diazetidomonapyridone Metabolites Control Biofilm Formation and Pigment Synthesis in Pseudomonas Aeruginosa. J. Am. Chem. Soc. 2022, 144 (17), 7676–7685. https://doi.org/10.1021/jacs.1c13653.

    • Greiffer L, Liebau E, Herrmann FC, Spiegler V (2022). Condensed tannins act as anthelmintics by increasing the rigidity of the nematode cuticle. Scientific Reports, 12, 18850. doi: 10.1038/s41598-022-23566-2. 1contributed equally to project supervision.

    • Hake A, Begrow F, Spiegler V, Symma N, Hensel A, Düfer M (2022) Extracts and Flavonoids from Drosera rotundifolia L. Increase Ciliary Beat Frequency and Exert an Antispasmodic Activity on Murine Airway Smooth Muscle. Molecules 27, 6622. doi.org/10.3390/molecules27196622.  

    • Jacobtorweihen J, Schmitt M., Spiegler V (2022). Amino acid-coupled bromophenols and a sulfated dimethylsulfonium lanosol from the red alga Vertebrata lanosa. Marine Drugs, 20, 420-436. doi: 10.3390/md20070420. 

    • Jato J, Orman E, Yaw DB, Oppong Bekoe E, Oppong Bekoe S, Asare-Nkansah S, Spiegler V, Hensel A, Liebau E, Agyare E (2022) Anthelmintic agents from African medicinal plants: review and prospects.  Evidence-Based Complementary and Alternative Medicine. 8023866. doi.org/10.1155/2022/8023866.

    • Jürgens FM, Behrens M, Humpf H-U, Robledo SM, Schmidt TJ (2022) In Vitro Metabolism of Helenalin Acetate and 11α,13-Dihydrohelenalin Acetate: Natural Sesquiterpene Lactones from Arnica. Metabolites 2022, 12, 88. DOI: 10.3390/metabo12010088.

    • Jürgens FM, Herrmann FC, Robledo SM, Schmidt TJ (2022) Dermal Absorption of Sesquiterpene Lactones from Arnica Tincture. Pharmaceutics 2022, 14, 742. DOI: 10.3390/pharmaceutics14040742.

    • Jürgens FM, Robledo SM, Schmidt TJ (2022) Evaluation of Pharmacokinetic and Toxicological Parameters of Arnica Tincture after Dermal Application In Vivo. Pharmaceutics 2022, 14, 2379. DOI; 10.3390/pharmaceutics14112379.

    • Krawczyk HE, Sun S, Doner NM, Yan Q, Lim MSS, Scholz P, Niemeyer PW, Schmitt K, Valerius O, Pleskot R, Hillmer S, Braus GH, Wiermer M, Mullen RT, Ischebeck T (2022) Seed lipid droplet protein1, seed lipid droplet protei2, and lipid droplet plasma membrane adaptor mediate lipid droplet-plasma membrane tethering. The Plant Cell 34, 2424-2448. doi.org/10.1093/plcell/koac095.

    • Mohamed FF, Anhlan D, Schöfbänker M, Schreiber A, Classen N, Hensel A, Hempel G, Scholz W, Kühn J, Hrincius ER, Ludwig S (2022) Hypericum perforatum and Its Ingredients Hypericin and Pseudohypericin Demonstrate an Antiviral Activity against SARS-CoV-2. Pharmaceuticals (Basel). 2022 Apr 25;15(5):530. doi: 10.3390/ph15050530.

    • Mo B, Sendker  J, Herrmann F, Nowak S, Hensel A (2022) Aqueous extract from Equisetum arvense stimulates the secretion of Tamm-Horsfall protein in human urine after oral intake. Phytomedicine 104, 154302, pp 1-13. doi.org/10.1016/j.phymed.2022.154302.

    • Orman E, Oppong Bekoe S, Jato J, Spiegler V, Asare-Nkansah S, Agyare C, Hensel A, Bekoe E (2022) Methodological Approaches to Herbal Medicines Quality Assessment in Africa: A Systematic Review of the Current Approaches and the Way Forward. Fitoterapia 162, 105287 DOI: 10.1016/j.fitote.2022.105287.

    • Possart K, Herrmann FC, Jose J, Costi MP, Schmidt TJ. Sesquiterpene Lactones with Dual Inhibitory Activity against the Trypanosoma brucei Pteridine Reductase 1 and Dihydrofolate Reductase. Molecules 2022, 27, 149. DOI: 10.3390/molecules27010149.

    • Robledo SM, Murillo J, Arbeláez N, Montoya A, Ospina V, Jürgens FM, Vélez ID, Schmidt TJ. Therapeutic efficacy of Arnica in hamsters with cutaneous leishmaniasis caused by Leishmania braziliensis and L. tropica. Pharmaceuticals 2022, 15, 776; DOI: 10.3390/ph15070776.

    •  

      Steinert K, Berg N, Kalinin DV, Jagels A, Würthwein E-U, Humpf H-U, Kalinina S (2022) Semisynthetic Approach toward Biologically Active Derivatives of Phenylspirodrimanes from S. chartarum. ACS Omega 2022, 7 (49), 45215–45230. https://doi.org/10.1021/acsomega.2c05681.

      Szabó LU, Schmidt TJ. Investigation of the Variability of Alkaloids in Buxus sempervirens L. Using Multivariate Data Analysis of LC/MS Profiles. Molecules 2022, 27, 82. DOI: 10.3390/molecules27010082.

  • 2021

    • Black D, Kaneko S, Walke A, König S, Stummer W, Suero Molina E (2021) Characterization of autofluorescence and quantitative protoporphyrin IX biomarkers for optical spectroscopy-guided glioma surgery. Scientific Reports, 11(1), 20009. DOI: 10.1038/s41598-021-99228-6.

    • Knetzger N, Bachtin V, Lehmann S, Hensel A, Liebau E, Herrmann F (2021) The anthelmintic quassinoids Ailanthone and Bruceine A induce infertility in the model organism Caenorhabditis elegans by an apoptotic mechanism induced in gonadal and spermathecal tissues. Molecules 26, 7354. doi.org/10.3390/molecules26237354.
    • Suero Molina E, Hellwig SJ, Walke A, Jeibmann A, Stepp H, Stummer W (2021) Development and validation of a triple-LED surgical loupe device for fluorescence-guided resections with 5-ALA. Journal of Neurosurgery 137(2). DOI: 10.3171/2021.10.JNS211911.

    • Szabó LU, Kaiser M, Mäser P, Schmidt TJ (2021) Antiprotozoal Nor-Triterpene Alkaloids from Buxus sempervirens L. Antibiotics 2021, 10, 696. DOI: 10.3390/antibiotics10060696.

    • Szabó LU, Kaiser M, Mäser P, Schmidt TJ (2021) Identification of Antiprotozoal Compounds from Buxus sempervirens L. by PLS-Prediction. Molecules 2021, 26, 6181. DOI: 10.3390/molecules26206181.

    • Walke A, König S (2021) Protorphyrin IX purification from blood and serum for mass analysis – considerations with respect to neurosurgery. Rapid Communications in Mass Spectrometry 35, 15: e9138, doi.org/10.1002/rcm.9138.
    • Wunsch FM, Wünsch B, Bernal FA, Schmidt TJ (2021) Quantitative Structure-Activity Relationships of Natural-Product-Inspired, Aminoalkyl-Substituted 1‑Benzopyrans as Novel Antiplasmodial Agents. Molecules 2021, 26, 5249. DOI: 10.3390/molecules26175249.