Edited by Barry G. Arnason
NeuroImmune Biology Volume 9
It is now well recognized that the brain, and especially the hypothalamus, plays an important role in the regulation of immune reactions and inflammation. This book aims to review our current state of knowledge of this important field. Key historical findings are presented and the reciprocal interactions between the brain and the immune system are examined. Particular emphasis is placed on inflammation, a critical host defense reaction which serves as an effector response for both the adaptive and innate immune systems Mechanisms implicated in brain defense, as well as in more general host defense, are discussed. The regulatory influences of the brain on inflammatory responses are included with particular reference to the role of the hypothalamus which is also the main director the hormonal regulation of immune/inflammatory. Gender related differences in immune responsiveness, circadian modulator of immune responses, and evidence that behavioural conditioning (e.g. reward) of immune responses is possible, are used as examples to reinforce the notion that the neuroendocrine system exerts a fundamental and complex regulatory influence on the immune system. It presents timely issues such as immunological aspects of the blood-brain-barrier and the role of inflammatory mediators in the evolution of strokes and degenerative diseases. It includes analysis of the role of the brain in the adaptive responses to disease. It evaluates the argument that further knowledge of the influence of the brain on the immune system will provide new insights to the pathophysiology infectious and autoimmune diseases.
Von „ABC Proteins“ bis „Zinc Oxide Bulk, Thin Films and Nanostructures“ stehen mehrere Tausend Titel aus dem Programm der niederländischen Verlagsgruppe und den dazugehörigen Verlagen zur Verfügung. Es handelt sich um naturwissenschaftliche, ingenieurswissenschaftliche und betriebswirtschaftliche Werke, die zunächst für ein Jahr nutzbar sind. Die eBooks können online gelesen und durchsucht, aber auch ausgedruckt oder für eigene wissenschaftliche Zwecke abgespeichert werden.