Im SFB 656 MoBil entstandene Publikationen

Die Namen der SFB-Teilprojektleiter sind fett dargestellt.


Axer A, Hermann S, Kehr G, Clases D, Karst U, Fischer-Riepe L, Roth J, Fobker M, Schafers M, Gilmour R, Faust A. Harnessing the Maltodextrin Transport Mechanism for Targeted Bacterial Imaging: Structural Requirements for Improved in vivo Stability in Tracer Design. ChemMedChem 2018;13: 241-250. Abstract
Bolwin K, Czekalla B, Frohwein LJ, Büther F, Schäfers KP. Anthropomorphic thorax phantom for cardio-respiratory motion simulation in tomographic imaging. Phys Med Biol 2018;63: 035009. Abstract
Bovay E, Sabine A, Prat-Luri B, Kim S, Son K, Willrodt A-H, Olsson C, Halin C, Kiefer F, Betsholtz C, Jeon NL, Luther SA, Petrova TV. Multiple roles of lymphatic vessels in peripheral lymph node development. J Exp Med 2018;215: 2760-2777. Abstract
Büther F, Ernst I, Frohwein LJ, Pouw J, Schafers KP, Stegger L. Data-driven gating in PET: Influence of respiratory signal noise on motion resolution. Med Phys 2018;45: 3205-3213. Abstract
Butsch V, Borgel F, Galla F, Schwegmann K, Hermann S, Schafers M, Riemann B, Wunsch B, Wagner S. Design, (Radio)Synthesis, and in Vitro and in Vivo Evaluation of Highly Selective and Potent Matrix Metalloproteinase 12 (MMP-12) Inhibitors as Radiotracers for Positron Emission Tomography. J Med Chem 2018;61: 4115-4134. Abstract
Duffy MJ, Planas O, Faust A, Vogl T, Hermann S, Schäfers M, Nonell S, Strassert CA. Towards optimized naphthalocyanines as sonochromes for photoacoustic imaging in vivo. Photoacoustics 2018;9: 49-61. Abstract
Frohwein LJ, Hess M, Schlicher D, Bolwin K, Büther F, Jiang X, Schäfers KP. PET attenuation correction for flexible MRI surface coils in hybrid PET/MRI using a 3D depth camera. Phys Med Biol 2018;63: 025033. Abstract
Gran S, Honold L, Fehler O, Zenker S, Eligehausen S, Kuhlmann MT, Geven E, den Bosch M van, van Lent P, Spiekermann C, Hermann S, Vogl T, Schäfers M, Roth J. Imaging, myeloid precursor immortalization, and genome editing for defining mechanisms of leukocyte recruitment_in vivo_. Theranostics 2018;8: 2407-2423. Abstract
Hägerling R, Hoppe E, Dierkes C, Stehling M, Makinen T, Butz S, Vestweber D, Kiefer F. Distinct roles of VE‐cadherin for development and maintenance of specific lymph vessel beds. EMBO J 2018: e98271. Abstract
Hohn M, Chang M, Meisel JE, Frost E, Schwegmann K, Hermann S, Schäfers M, Riemann B, Haufe G, Breyholz HJ, Wagner S. Synthesis and preliminary in vitro and in vivo evaluation of thiirane-based slow binding MMP inhibitors as potential radiotracers for PET imaging. Chemistry Select 2018;3: 11729-11736. Abstract
Hugenberg V, Behrends M, Wagner S, Hermann S, Schafers M, Kolb HC, Szardenings K, Walsh JC, Gomez LF, Kopka K, Haufe G. Synthesis, radiosynthesis, in vitro and first in vivo evaluation of a new matrix metalloproteinase inhibitor based on gamma-fluorinated alpha-sulfonylaminohydroxamic acid. EJNMMI Radiopharm Chem 2018;3: 10. Abstract
Orlich M, Kiefer F. A qualitative comparison of ten tissue clearing techniques. Histol Histopathol 2018;33: 181-199. Abstract
Reips L, Burger M, Engbers R. Towards dynamic PET reconstruction under flow conditions: Parameter identification in a PDE model. Journal of Inverse and Ill-posed Problems 2018;26: 185-200. Abstract
Voeller T, Faust A, Roth J, Schafers M, Vogl T, Hermann S. A Non-Peptidic S100A9 Specific Ligand for Optical Imaging of Phagocyte Activity In Vivo. Mol Imaging Biol 2018;20: 407-416. Abstract
Vogl T, Stratis A, Wixler V, Voller T, Thurainayagam S, Jorch SK, Zenker S, Dreiling A, Chakraborty D, Frohling M, Paruzel P, Wehmeyer C, Hermann S, Papantonopoulou O, Geyer C, Loser K, Schafers M, Ludwig S, Stoll M, Leanderson T, Schultze JL, Konig S, Pap T, Roth J. Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation. J Clin Invest 2018;128: 1852-1866. Abstract
Zumhagen S, Vrachimis A, Stegger L, Kies P, Wenning C, Ernsting M, Muller J, Seebohm G, Paul M, Schafers K, Stallmeyer B, Schafers M, Schulze-Bahr E. Impact of presynaptic sympathetic imbalance in long-QT syndrome by positron emission tomography. Heart 2018;104: 332-339. Abstract


Abdurrachim D, Nabben M, Hoerr V, Kuhlmann MT, Bovenkamp P, Ciapaite J, Geraets IME, Coumans W, Luiken JJFP, Glatz JFC, Schafers M, Nicolay K, Faber C, Hermann S, Prompers JJ. Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations. Cardiovasc Res 2017;113: 1148-1160. Abstract
Bartels K, Schinor B, Haufe G. Diastereoselectivity of cyclopropanation of substituted α-fluorostyrenes versus styrenes by different methods. Journal of Fluorine Chemistry 2017;203: 200-205. Abstract
Bian A, Scherzinger A, Jiang X. An enhanced multi-label random walk for biomedical image segmentation using statistical seed generation. In: Blanc-Talon et al. (Eds.): ACIVS 2017, LNCS 10617 2017;Springer, Cham: 748–760. Abstract
Bolwin K, Vernekohl D, Lühder J, Czekalla B, Wessels JP, Schäfers KP. Development of a clear sub-millimeter small animal PET scanner by reducing the influence of the non-collinearity effect. J. Inst. 2017;12: C03006-C03006. Abstract
Borrello MT, Schinor B, Bartels K, Benelkebir H, Pereira S, Al-Jamal WT, Douglas L, Duriez PJ, Packham G, Haufe G, Ganesan A. Fluorinated tranylcypromine analogues as inhibitors of lysine-specific demethylase 1 (LSD1, KDM1A). Bioorg Med Chem Lett 2017;27: 2099-2101. Abstract
Breyholz H-J, Kopka K, Schafers M, Wagner S. Syntheses of Radioiodinated Pyrimidine-2,4,6-Triones as Potential Agents for Non-Invasive Imaging of Matrix Metalloproteinases. Pharmaceuticals (Basel) 2017;10Abstract
Decher N, Ortiz-Bonnin B, Friedrich C, Schewe M, Kiper AK, Rinne S, Seemann G, Peyronnet R, Zumhagen S, Bustos D, Kockskamper J, Kohl P, Just S, Gonzalez W, Baukrowitz T, Stallmeyer B, Schulze-Bahr E. Sodium permeable and "hypersensitive" TREK-1 channels cause ventricular tachycardia. EMBO Mol Med 2017: e201606690. Abstract
Dedner A, Girke S, Klöfkorn R, Malkmus T. The Dune-Fem-DG module. Archive of Numerical Software 2017;5: 1–62.
Dunaeva M, Waltenberger J. Hh signaling in regeneration of the ischemic heart. Cell Mol Life Sci 2017;74: 3481-3490. Abstract
Hagerling R, Drees D, Scherzinger A, Dierkes C, Martin-Almedina S, Butz S, Gordon K, Schafers M, Hinrichs K, Ostergaard P, Vestweber D, Goerge T, Mansour S, Jiang X, Mortimer PS, Kiefer F. VIPAR, a quantitative approach to 3D histopathology applied to lymphatic malformations. JCI Insight 2017;2Abstract
Hess M, Buther F, Schafers KP. Data-Driven Methods for the Determination of Anterior-Posterior Motion in PET. IEEE Trans Med Imaging 2017;36: 422-432. Abstract
Höltke C, Faust A. Molecular imaging of integrins in oncology. Rmi 2017;Volume 10: 17-30. Abstract
Hugenberg V, Wagner S, Kopka K, Schafers M, Schuit RC, Windhorst AD, Hermann S. Radiolabeled Selective Matrix Metalloproteinase 13 (MMP-13) Inhibitors: (Radio)Syntheses and in Vitro and First in Vivo Evaluation. J Med Chem 2017;60: 307-321. Abstract
Karpanen T, Padberg Y, van de Pavert SA, Dierkes C, Morooka N, Peterson-Maduro J, van de Hoek G, Adrian M, Mochizuki N, Sekiguchi K, Kiefer F, Schulte D, Schulte-Merker S. An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation. Circ Res 2017;120: 1263-1275. Abstract
Kentrup D, Bovenkamp P, Busch A, Schuette-Nuetgen K, Pawelski H, Pavenstadt H, Schlatter E, Herrmann K-H, Reichenbach JR, Loffler B, Heitplatz B, Van Marck V, Yadav NN, Liu G, van Zijl PCM, Reuter S, Hoerr V. GlucoCEST magnetic resonance imaging in vivo may be diagnostic of acute renal allograft rejection. Kidney Int 2017;92: 757-764. Abstract
Kozel V, Daniliuc C-G, Kirsch P, Haufe G. C3 -Symmetric Tricyclo[2210(2,6) ]heptane-3,5,7-triol. Angew Chem Int Ed Engl 2017;56: 15456-15460. Abstract
Lange PS, Avramovic N, Frommeyer G, Wasmer K, Pott C, Eckardt L, Wenning C. Routine 18F-FDG PET/CT does not detect inflammation in the left atrium in patients with atrial fibrillation. Int J Cardiovasc Imaging 2017;33: 1271-1276. Abstract
Noto B, Buther F, Auf der Springe K, Avramovic N, Heindel W, Schafers M, Allkemper T, Stegger L. Impact of PET acquisition durations on image quality and lesion detectability in whole-body 68Ga-PSMA PET-MRI. EJNMMI Res 2017;7: 12. Abstract
Ortmeyer CP, Haufe G, Schwegmann K, Hermann S, Schafers M, Borgel F, Wunsch B, Wagner S, Hugenberg V. Synthesis and evaluation of a [18F]BODIPY-labeled caspase-inhibitor. Bioorg Med Chem 2017;25: 2167-2176. Abstract
Scherzinger A, Brix T, Drees D, Volker A, Radkov K, Santalidis N, Fieguth A, Hinrichs KH. Interactive Exploration of Cosmological Dark-Matter Simulation Data. IEEE Comput Graph Appl 2017;37: 80-89. Abstract
Seifert R, Scherzinger A, Kiefer F, Hermann S, Jiang X, Schafers MA. Statistical Permutation-based Artery Mapping (SPAM): a novel approach to evaluate imaging signals in the vessel wall. BMC Med Imaging 2017;17: 36. Abstract
Stallmeyer B, Kuss J, Kotthoff S, Zumhagen S, Vowinkel K, Rinne S, Matschke LA, Friedrich C, Schulze-Bahr E, Rust S, Seebohm G, Decher N, Schulze-Bahr E. A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction. Circ Res 2017;120: e33-e44. Abstract
Van de Vyver H, Bovenkamp PR, Hoerr V, Schwegmann K, Tuchscherr L, Niemann S, Kursawe L, Grosse C, Moter A, Hansen U, Neugebauer U, Kuhlmann MT, Peters G, Hermann S, Loffler B. A Novel Mouse Model of Staphylococcus aureus Vascular Graft Infection: Noninvasive Imaging of Biofilm Development in Vivo. Am J Pathol 2017;187: 268-279. Abstract


Anneken L, Baumann S, Vigneault P, Biliczki P, Friedrich C, Xiao L, Girmatsion Z, Takac I, Brandes RP, Kissler S, Wiegratz I, Zumhagen S, Stallmeyer B, Hohnloser SH, Klingenheben T, Schulze-Bahr E, Nattel S, Ehrlich JR. Estradiol regulates human QT-interval: acceleration of cardiac repolarization by enhanced KCNH2 membrane trafficking. Eur Heart J 2016;37: 640-650. Abstract
Bettenworth D, Mucke MM, Schwegmann K, Faust A, Poremba C, Schafers M, Domagk D, Lenz P. Endoscopy-guided orthotopic implantation of colorectal cancer cells results in metastatic colorectal cancer in mice. Clin Exp Metastasis 2016;33: 551-562. Abstract
Beutel B, Daniliuc CG, Riemann B, Schafers M, Haufe G. Fluorinated matrix metalloproteinases inhibitors-Phosphonate based potential probes for positron emission tomography. Bioorg Med Chem 2016;24: 902-909. Abstract
Bian A, Jiang X. Statistical Modeling Based Adaptive Parameter Setting for Random Walk Segmentation. Lect Notes Comput Sc 2016;10016: 698-710. Abstract
Buther F, Vehren T, Schafers KP, Schafers M. Impact of Data-driven Respiratory Gating in Clinical PET. Radiology 2016: 152067. Abstract
Büther F, Vrachimis A, Becker A, Stegger L. Impact of MR-safe headphones on PET attenuation in combined PET/MRI scans. EJNMMI Res 2016;6: 20. Abstract
Erapaneedi R, Belousov VV, Schafers M, Kiefer F. A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level. Embo J 2016;35: 102-113. Abstract
Faust A, Hermann S, Schafers M, Holtke C. Optical imaging probes and their potential contribution to radiotracer development. Nuklearmedizin 2016;55: 51-62. Abstract
Galla F, Bourgeois C, Lehmkuhl K, Schepmann D, Soeberdt M, Lotts T, Abels C, Ständer S, Wünsch B. Effects of polar κ receptor agonists designed for the periphery on ATP-induced Ca[super:2+]release from keratinocytes. Med. Chem. Commun. 2016;7: 317-326. Abstract
Galstyan A, Block D, Niemann S, Gruner MC, Abbruzzetti S, Oneto M, Daniliuc CG, Hermann S, Viappiani C, Schafers M, Loffler B, Strassert CA, Faust A. Labeling and Selective Inactivation of Gram-Positive Bacteria Employing Bimodal Photoprobes with Dual Readouts. Chemistry 2016;22: 5243-5252. Abstract
Geven EJW, van den Bosch MHJ, Di Ceglie I, Ascone G, Abdollahi-Roodsaz S, Sloetjes AW, Hermann S, Schafers M, van de Loo FAJ, van der Kraan PM, Koenders MI, Foell D, Roth J, Vogl T, van Lent PLEM. S100A8/A9, a potent serum and molecular imaging biomarker for synovial inflammation and joint destruction in seronegative experimental arthritis. Arthritis Res Ther 2016;18: 247. Abstract
Grabner A, Kentrup D, Muhlmeister M, Pawelski H, Biermann C, Bettinger T, Pavenstadt H, Schlatter E, Tiemann K, Reuter S. Noninvasive Imaging of Acute Renal Allograft Rejection by Ultrasound Detection of Microbubbles Targeted to T-lymphocytes in Rats. Ultraschall Med 2016;37: 82-91. Abstract
Grabner A, Kentrup D, Pawelski H, Muhlmeister M, Biermann C, Edemir B, Heitplatz B, Van Marck V, Bettinger T, Pavenstadt H, Schlatter E, Stypmann J, Tiemann K, Reuter S. Renal Contrast-Enhanced Sonography Findings in a Model of Acute Cellular Allograft Rejection. Am J Transplant 2016;16: 1612-1619. Abstract
Hermann S, Kuhlmann MT, Starsichova A, Eligehausen S, Schafers K, Stypmann J, Tiemann K, Levkau B, Schafers M. Imaging Reveals the Connection Between Spontaneous Coronary Plaque Ruptures, Atherothrombosis, and Myocardial Infarctions in HypoE/SRBI-/- Mice. J Nucl Med 2016;57: 1420-1427. Abstract
Hugenberg V, Hermann S, Galla F, Schafers M, Wunsch B, Kolb HC, Szardenings K, Lebedev A, Walsh JC, Mocharla VP, Gangadharmath UB, Kopka K, Wagner S. Radiolabeled hydroxamate-based matrix metalloproteinase inhibitors: How chemical modifications affect pharmacokinetics and metabolic stability. Nucl Med Biol 2016;43: 424-437. Abstract
Itoh H, Berthet M, Fressart V, Denjoy I, Maugenre S, Klug D, Mizusawa Y, Makiyama T, Hofman N, Stallmeyer B, Zumhagen S, Shimizu W, Wilde AAM, Schulze-Bahr E, Horie M, Tezenas du Montcel S, Guicheney P. Asymmetry of parental origin in long QT syndrome: preferential maternal transmission of KCNQ1 variants linked to channel dysfunction. Eur J Hum Genet 2016;24: 1160-1166. Abstract
Keul P, van Borren MMGJ, Ghanem A, Muller FU, Baartscheer A, Verkerk AO, Stumpel F, Schulte JS, Hamdani N, Linke WA, van Loenen P, Matus M, Schmitz W, Stypmann J, Tiemann K, Ravesloot J-H, Alewijnse AE, Hermann S, Spijkers LJA, Hiller K-H, Herr D, Heusch G, Schafers M, Peters SLM, Chun J, Levkau B. Sphingosine-1-Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning. J Am Heart Assoc 2016;5: e003393. Abstract
Pardali E, Schmitz T, Borgscheiper A, Iking J, Stegger L, Waltenberger J. Cryopreservation of primary human monocytes does not negatively affect their functionality or their ability to be labelled with radionuclides: basis for molecular imaging and cell therapy. EJNMMI Res 2016;6: 77. Abstract
Ramb DC, Lerchen A, Kischkewitz M, Beutel B, Fustero S, Haufe G. Addition of Nucleophiles to Fluorinated Michael Acceptors. Eur. J. Org. Chem. 2016;2016: 1751-1759. Abstract
Reinartz G, Haverkamp U, Wullenkord R, Lehrich P, Kriz J, Buther F, Schafers K, Schafers M, Eich HT. 4D-Listmode-PET-CT and 4D-CT for optimizing PTV margins in gastric lymphoma : Determination of intra- and interfractional gastric motion. Strahlenther Onkol 2016;192: 322-332. Abstract
Reuter S, Reiermann S, Malyar V, Schutte-Nutgen K, Schmidt R, Pavenstadt H, Reinecke H, Suwelack B. A Comparison of Different Algorithms for the Assessment of Cardiovascular Risk in Patients at Waiting List for Kidney Transplantation. PLoS One 2016;11: e0161927. Abstract
Scherzinger A, Kleene F, Dierkes C, Kiefer F, Hinrichs K, Jiang X. Automated Segmentation of Immunostained Cell Nuclei in 3D Ultramicroscopy Images. In: Pattern Recognition - 38th German Conference, GCPR 2016, Hannover, Germany, Sept. 12-15, 2016;Springer: 105-116. Abstract
Schwegmann K, Bettenworth D, Hermann S, Faust A, Poremba C, Foell D, Schafers M, Domagk D, Lenz P. Detection of Early Murine Colorectal Cancer by MMP-2/-9-Guided Fluorescence Endoscopy. Inflamm Bowel Dis 2016;22: 82-91. Abstract
Tholking G, Schuette-Nuetgen K, Kentrup D, Pawelski H, Reuter S. Imaging-based diagnosis of acute renal allograft rejection. World J Transplant 2016;6: 174-182. Abstract
Tulumen E, Schulze-Bahr E, Zumhagen S, Stallmeyer B, Seebohm G, Beckmann B-M, Kaab S, Rudic B, Liebe V, Wolpert C, Herrera-Siklody C, Veltmann C, Schimpf R, Borggrefe M. Early repolarization pattern: a marker of increased risk in patients with catecholaminergic polymorphic ventricular tachycardia. Europace 2016;18: 1587-1592. Abstract
Ulbrich D, Daniliuc CG, Haufe G. Halofluorination of N-protected α,β-dehydro-α-amino acid esters—A convenient synthesis of α-fluoro-α-amino acid derivatives. Journal of Fluorine Chemistry 2016;188: 65-75. Abstract
Vrachimis A, Honold L, Faust A, Hermann S, Schafers M. New molecular probes of vascular inflammation. Q J Nucl Med Mol Imaging 2016;60: 194-204. Abstract
Vrachimis A, Stegger L, Wenning C, Noto B, Burg MC, Konnert JR, Allkemper T, Heindel W, Riemann B, Schafers M, Weckesser M. [(68)Ga]DOTATATE PET/MRI and [(18)F]FDG PET/CT are complementary and superior to diffusion-weighted MR imaging for radioactive-iodine-refractory differentiated thyroid cancer. Eur J Nucl Med Mol Imaging 2016;43: 1765-1772. Abstract
Weber F, Brune S, Borgel F, Lange C, Korpis K, Bednarski PJ, Laurini E, Fermeglia M, Pricl S, Schepmann D, Wunsch B. Rigidity versus Flexibility: Is This an Issue in sigma1 Receptor Ligand Affinity and Activity?. J Med Chem 2016;59: 5505-5519. Abstract
Wiese C, Grosse Maestrup E, Galla F, Schepmann D, Hiller A, Fischer S, Ludwig F-A, Deuther-Conrad W, Donat CK, Brust P, Buter L, Karst U, Wunsch B. Comparison of in Silico, Electrochemical, in Vitro and in Vivo Metabolism of a Homologous Series of (Radio)fluorinated σ1 Receptor Ligands Designed for Positron Emission Tomography. ChemMedChem 2016;11: 2445–2458. Abstract
Zumhagen S, Zeidler EM, Stallmeyer B, Ernsting M, Eckardt L, Schulze-Bahr E. Tpeak-Tend interval and Tpeak-Tend/QT ratio in patients with Brugada syndrome. Europace 2016;18: 1866-1872. Abstract


Bălan M, Kiefer F. A novel model for ectopic, chronic, intravital multiphoton imaging of bone marrow vasculature and architecture in split femurs. IntraVital 2015;4: e1066949. Abstract
Behrends M, Wagner S, Kopka K, Schober O, Schafers M, Kumbhar S, Waller M, Haufe G. New matrix metalloproteinase inhibitors based on gamma-fluorinated alpha-aminocarboxylic and alpha-aminohydroxamic acids. Bioorg Med Chem 2015;23: 3809-3818. Abstract
Bovenkamp PR, Brix T, Lindemann F, Holtmeier R, Abdurrachim D, Kuhlmann MT, Strijkers GJ, Stypmann J, Hinrichs KH, Hoerr V. Velocity mapping of the aortic flow at 94 T in healthy mice and mice with induced heart failure using time-resolved three-dimensional phase-contrast MRI (4D PC MRI). Magma 2015;28: 315-327. Abstract
Brix T, Scherzinger A, Völker A, Hinrichs K. Interactive Position-dependent Customization of Transfer Function Classification Parameters in Volume Rendering. EG VCBM 2015Abstract
Di Marco GS, Kentrup D, Reuter S, Mayer AB, Golle L, Tiemann K, Fobker M, Engelbertz C, Breithardt G, Brand E, Reinecke H, Pavenstadt H, Brand M. Soluble Flt-1 links microvascular disease with heart failure in CKD. Basic Res Cardiol 2015;110: 487. Abstract
Ersepke T, Buther F, Hess M, Schafers KP. A contactless approach for respiratory gating in PET using continuous-wave radar. Med Phys 2015;42: 4911. Abstract
Faust A, Voller T, Busch F, Schafers M, Roth J, Hermann S, Vogl T. Development and evaluation of a non-peptidic ligand for the molecular imaging of inflammatory processes using S100A9 (MRP14) as a novel target. Chem Commun (Camb) 2015;51: 15637-15640. Abstract
Frohwein LJ, Hoerr V, Faber C, Schäfers KP. Correction of MRI-induced geometric distortions in whole-body small animal PET-MRI. Med. Phys. 2015;42: 3848-3858. Abstract
Fustero S, Simon-Fuentes A, Barrio P, Haufe G. Olefin metathesis reactions with fluorinated substrates, catalysts, and solvents. Chem Rev 2015;115: 871-930. Abstract
Grabner A, Amaral AP, Schramm K, Singh S, Sloan A, Yanucil C, Li J, Shehadeh LA, Hare JM, David V, Martin A, Fornoni A, Di Marco GS, Kentrup D, Reuter S, Mayer AB, Pavenstadt H, Stypmann J, Kuhn C, Hille S, Frey N, Leifheit-Nestler M, Richter B, Haffner D, Abraham R, Bange J, Sperl B, Ullrich A, Brand M, Wolf M, Faul C. Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy. Cell Metab 2015;22: 1020-1032. Abstract
Heß M, Büther F, Gigengack F, Dawood M, Schäfers KP. A dual-Kinect approach to determine torso surface motion for respiratory motion correction in PET. Med. Phys. 2015;42: 2276-2286. Abstract
Junker A, Kokornaczyk AK, Strunz AK, Wünsch B. Selective and Dual Targeting of CCR2 and CCR5 Receptors: A Current Overview. Top Med Chem 2015;14: 187-241. Abstract
Junker A, Kokornaczyk AK, Zweemer AJM, Frehland B, Schepmann D, Yamaguchi J, Itami K, Faust A, Hermann S, Wagner S, Schafers M, Koch M, Weiss C, Heitman LH, Kopka K, Wunsch B. Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists. Org Biomol Chem 2015;13: 2407-2422. Abstract
Klenner L, Hafezi W, Clausen BE, Lorentzen EU, Luger TA, Beissert S, Kuhn JE, Loser K. Cutaneous RANK-RANKL Signaling Upregulates CD8-Mediated Antiviral Immunity during Herpes simplex Virus Infection by Preventing Virus-Induced Langerhans Cell Apoptosis. J Invest Dermatol 2015;135: 2676-2687. Abstract
Limpachayaporn P, Schafers M, Haufe G. Isatin sulfonamides: potent caspases-3 and -7 inhibitors, and promising PET and SPECT radiotracers for apoptosis imaging. Future Med Chem 2015;7: 1173-1196. Abstract
Nussbaum C, Bannenberg S, Keul P, Graler MH, Goncalves-de-Albuquerque CF, Korhonen H, von Wnuck Lipinski K, Heusch G, de Castro Faria Neto HC, Rohwedder I, Gothert JR, Prasad VP, Haufe G, Lange-Sperandio B, Offermanns S, Sperandio M, Levkau B. Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin. Nat Commun 2015;6: 6416. Abstract
Santschi N, Wagner S, Daniliuc C, Hermann S, Schafers M, Gilmour R. Synthesis of 2-[(18) F]Fluoro-2-deoxyisosorbide 5-mononitrate and Assessment of Its in vivo Biodistribution as Determined by Dynamic Positron Emission Tomography (PET). ChemMedChem 2015;10: 1724-1732. Abstract
Sattler K, Graler M, Keul P, Weske S, Reimann C-M, Jindrova H, Kleinbongard P, Sabbadini R, Brocker-Preuss M, Erbel R, Heusch G, Levkau B. Defects of High-Density Lipoproteins in Coronary Artery Disease Caused by Low Sphingosine-1-Phosphate Content: Correction by Sphingosine-1-Phosphate-Loading. J Am Coll Cardiol 2015;66: 1470-1485. Abstract
Schilson SS, Keul P, Shaikh RS, Schafers M, Levkau B, Haufe G. Synthesis of new ligands for targeting the S1P1 receptor. Bioorg Med Chem 2015;23: 1011-1026. Abstract
Schmid S, Jiang X, Schafers K. Puzzle Approach to Pose Tracking of a Rigid Object in a Multi Camera System. Lect Notes Comput Sc 2015;9256: 337-349. Abstract
Schulze-Bahr E, Klaassen S, Abdul-Khaliq H, Schunkert H. [Molecular diagnosis for cardiovascular diseases]. Dtsch Med Wochenschr 2015;140: 1538. Abstract
Shaikh RS, Keul P, Schäfers M, Levkau B, Haufe G. New fluorinated agonists for targeting the sphingosin-1-phosphate receptor 1 (S1P1). Bioorganic & Medicinal Chemistry Letters 2015;25: 5048-5051. Abstract
Shaikh RS, Schilson SS, Wagner S, Hermann S, Keul P, Levkau B, Schafers M, Haufe G. Synthesis and evaluation of fluorinated fingolimod (FTY720) analogues for sphingosine-1-phosphate receptor molecular imaging by positron emission tomography. J Med Chem 2015;58: 3471-3484. Abstract
Song J, Wu C, Korpos E, Zhang X, Agrawal SM, Wang Y, Faber C, Schafers M, Korner H, Opdenakker G, Hallmann R, Sorokin L. Focal MMP-2 and MMP-9 Activity at the Blood-Brain Barrier Promotes Chemokine-Induced Leukocyte Migration. Cell Rep 2015;10: 1040-1054. Abstract
Stallmeyer B, Schulze-Bahr E. Cardiovascular disease and sudden cardiac death: between genetics and genomics. Eur Heart J 2015;36: 1643-1645. Abstract
Strunz AK, Zweemer AJM, Weiss C, Schepmann D, Junker A, Heitman LH, Koch M, Wunsch B. Synthesis and biological evaluation of spirocyclic antagonists of CCR2 (chemokine CC receptor subtype 2). Bioorg Med Chem 2015;23: 4034-4049. Abstract
Tenbrinck D, Jiang X. Image segmentation with arbitrary noise models by solving minimal surface problems. Pattern Recognition 2015;48: 3293-3309. Abstract
Waldmann CM, Hermann S, Faust A, Riemann B, Schober O, Schafers M, Haufe G, Kopka K. Novel fluorine-18 labeled 5-(1-pyrrolidinylsulfonyl)-7-azaisatin derivatives as potential PET tracers for in vivo imaging of activated caspases in apoptosis. Bioorg Med Chem 2015;23: 5734-5739. Abstract
Wenning C, Vrachimis A, Dell Aquila A, Penning A, Stypmann J, Schafers M. Inhomogeneous myocardial stress perfusion in SPECT studies predicts future allograft dysfunction in heart transplant recipients. EJNMMI Res 2015;5: 51. Abstract
Wu Z, Jiang X, Zheng N, Cheng D. Efficient block-wise temporally consistent contour,extraction in image sequences. Neurocomputing 2015;152: 127-138. Abstract
Wu Z, Jiang X, Zheng N, Liu Y, Cheng D. Exact solution to median surface problem using 3D graph search and application to parameter space exploration. Pattern Recognition 2015;48: 380-390. Abstract
Zinnhardt B, Viel T, Wachsmuth L, Vrachimis A, Wagner S, Breyholz H-J, Faust A, Hermann S, Kopka K, Faber C, Dolle F, Pappata S, Planas AM, Tavitian B, Schafers M, Sorokin LM, Kuhlmann MT, Jacobs AH. Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke. J Cereb Blood Flow Metab 2015;35: 1711-1721. Abstract


Alsibai W, Hahnenkamp A, Eisenblatter M, Riemann B, Schafers M, Bremer C, Haufe G, Holtke C. Fluorescent Non-peptidic RGD Mimetics with High Selectivity for alphaVbeta3 vs alphaIIbbeta3 Integrin Receptor: Novel Probes for in Vivo Optical Imaging. J Med Chem 2014;57: 9971-9982. Abstract
Bourgeois C, Werfel E, Galla F, Lehmkuhl K, Torres-Gomez H, Schepmann D, Kogel B, Christoph T, Strassburger W, Englberger W, Soeberdt M, Huwel S, Galla H-J, Wunsch B. Synthesis and pharmacological evaluation of 5-pyrrolidinylquinoxalines as a novel class of peripherally restricted kappa-opioid receptor agonists. J Med Chem 2014;57: 6845-6860. Abstract
Burger M, Müller J, Papoutsellis E, Schönlieb CB. Total variation regularization in measurement and image space for PET reconstruction. Inverse Probl 2014;30: 105003. Abstract
D'Amico G, Korhonen EA, Anisimov A, Zarkada G, Holopainen T, Hagerling R, Kiefer F, Eklund L, Sormunen R, Elamaa H, Brekken RA, Adams RH, Koh GY, Saharinen P, Alitalo K. Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy. J Clin Invest 2014;124: 824-834. Abstract
Dartsch N, Schulte D, Hagerling R, Kiefer F, Vestweber D. Fusing VE-Cadherin to alpha-Catenin Impairs Fetal Liver Hematopoiesis and Lymph but Not Blood Vessel Formation. Mol Cell Biol 2014;34: 1634-1648. Abstract
Di Marco GS, Reuter S, Kentrup D, Grabner A, Amaral AP, Fobker M, Stypmann J, Pavenstadt H, Wolf M, Faul C, Brand M. Treatment of established left ventricular hypertrophy with fibroblast growth factor receptor blockade in an animal model of CKD. Nephrol Dial Transplant 2014;29: 2028-2035. Abstract
Fieseler M, Gigengack F, Jiang X, Schafers KP. Motion correction of whole-body PET data with a joint PET-MRI registration functional. Biomed Eng Online 2014;13 Suppl 1: S2. Abstract
Girke S, Klöfkorn R, Ohlberger M. Efficient Parallel Simulation of Atherosclerotic Plaque Formation Using Higher Order Discontinuous Galerkin Schemes. PROM 2014;78: 617-625. Abstract
Hahnenkamp A, Alsibai W, Bremer C, Holtke C. Optimizing the bioavailability of small molecular optical imaging probes by conjugation to an albumin affinity tag. J Control Release 2014;186: 32-40. Abstract
Hoerr V, Faber C. Magnetic resonance imaging characterization of microbial infections. J Pharm Biomed Anal 2014;93: 136-146. Abstract
Junker A, Schepmann D, Yamaguchi J, Itami K, Faust A, Kopka K, Wagner S, Wünsch B. Diverse modifications of the 4-methylphenyl moiety of TAK-779 by late-stage Suzuki-Miyaura cross-coupling. Org Biomol Chem 2014;12: 177-186. Abstract
Lenz P, Meister T, Manno M, Pennazio M, Conigliaro R, Lebkücher S, Ullerich H, Schmedt A, Floer M, Beyna T, Lenze F, Domagk D. CO2 insufflation during single-balloon enteroscopy: a multicenter randomized controlled trial. Endoscopy 2014: 53-58. Abstract
Limpachayaporn P, Wagner S, Kopka K, Schober O, Schafers M, Haufe G. Synthesis of 7-halogenated isatin sulfonamides: nonradioactive counterparts of caspase-3/-7 inhibitor-based potential radiopharmaceuticals for molecular imaging of apoptosis. J Med Chem 2014;57: 9383-9395. Abstract
Padberg J-S, Wiesinger A, di Marco GS, Reuter S, Grabner A, Kentrup D, Lukasz A, Oberleithner H, Pavenstadt H, Brand M, Kumpers P. Damage of the endothelial glycocalyx in chronic kidney disease. Atherosclerosis 2014;234: 335-343. Abstract
Paul M, Kies P, Schafers M, Schulze-Bahr E. Cardiac sympathetic innervation in a patient with catecholaminergic polymorphic ventricular tachycardia. Heart Rhythm 2014;11: 1490-1491. Abstract
Pawelski H, Lang D, Reuter S. Interactions of monocytes and platelets: implication for life. Front Biosci (Schol Ed) 2014;6: 75-91. Abstract
Pawelski H, Schnockel U, Kentrup D, Grabner A, Schafers M, Reuter S. SPECT- and PET-Based Approaches for Noninvasive Diagnosis of Acute Renal Allograft Rejection. Biomed Res Int 2014;2014: 874785. Abstract
Persigehl T, Ring J, Bremer C, Heindel W, Holtmeier R, Stypmann J, Claesener M, Hermann S, Schafers M, Zerbst C, Schliemann C, Mesters RM, Berdel WE, Schwoppe C. Non-invasive monitoring of tumor-vessel infarction by retargeted truncated tissue factor tTF-NGR using multi-modal imaging. Angiogenesis 2014;17: 235-246. Abstract
Prasad VP, Wagner S, Keul P, Hermann S, Levkau B, Schafers M, Haufe G. Synthesis of fluorinated analogues of sphingosine-1-phosphate antagonists as potential radiotracers for molecular imaging using positron emission tomography. Bioorg Med Chem 2014;22: 5168-5181. Abstract
Ring J, Hoerr V, Tuchscherr L, Kuhlmann MT, Loffler B, Faber C. MRI Visualization of Staphyloccocus aureus-Induced Infective Endocarditis in Mice. PLoS One 2014;9: e107179. Abstract
Schmidt R, Nippe N, Strobel K, Masthoff M, Reifschneider O, Castelli DD, Holtke C, Aime S, Karst U, Sunderkotter C, Bremer C, Faber C. Highly Shifted Proton MR Imaging: Cell Tracking by Using Direct Detection of Paramagnetic Compounds. Radiology 2014;272: 785-795. Abstract
Ungru K, Tenbrinck D, Jiang X, Stypmann J. Automatic classification of left ventricular wall segments in small animal ultrasound imaging. Comput Methods Programs Biomed 2014;117: 2-12. Abstract
van Duijnhoven SMJ, Robillard MS, Hermann S, Kuhlmann MT, Schafers M, Nicolay K, Grull H. Imaging of MMP activity in postischemic cardiac remodeling using radiolabeled MMP-2/9 activatable peptide probes. Mol Pharm 2014;11: 1415-1423. Abstract
Vogl T, Eisenblatter M, Voller T, Zenker S, Hermann S, van Lent P, Faust A, Geyer C, Petersen B, Roebrock K, Schafers M, Bremer C, Roth J. Alarmin S100A8/S100A9 as a biomarker for molecular imaging of local inflammatory activity. Nat Commun 2014;5: 4593. Abstract
Wenning C, Kloth C, Kuhlmann MT, Jacobs AH, Schober O, Hermann S, Schafers MA. Serial F-18-FDG PET/CT distinguishes inflamed from stable plaque phenotypes in shear-stress induced murine atherosclerosis. Atherosclerosis 2014;234: 276-282. Abstract
Werdan K, Dietz S, Löffler B, Niemann S, Bushnaq H, Silber RE, Peters G, Müller-Werdan U. Mechanisms of infective endocarditis: pathogen-host interaction and risk states. Nat Rev Cardiol 2014;11: 35-50. Abstract


Benning M, Brune C, Burger M, Müller J. Higher-Order TV Methods - Enhancement via Bregman Iteration. J Sci Comput 2013;54: 269-310. Abstract
Bettenworth D, Reuter S, Hermann S, Weckesser M, Kerstiens L, Stratis A, Nowacki TM, Ross M, Lenze F, Edemir B, Maaser C, Pap T, Koschmieder S, Heidemann J, Schäfers M, Lugering A. Translational 18F-FDG PET/CT Imaging to Monitor Lesion Activity in Intestinal Inflammation. J Nucl Med 2013;54: 748-755. Abstract
Bezzina CR, Barc J, Mizusawa Y, Remme CA, Gourraud J-B, Simonet F, Verkerk AO, Schwartz PJ, Crotti L, Dagradi F, Guicheney P, Fressart V, Leenhardt A, Antzelevitch C, Bartkowiak S, Schulze-Bahr E, Zumhagen S, Behr ER, Bastiaenen R, Tfelt-Hansen J, Olesen MS, Kaab S, Beckmann BM, Weeke P, Watanabe H, Endo N, Minamino T, Horie M, Ohno S, Hasegawa K, Makita N, Nogami A, Shimizu W, Aiba T, Froguel P, Balkau B, Lantieri O, Torchio M, Wiese C, Weber D, Wolswinkel R, Coronel R, Boukens BJ, Bezieau S, Charpentier E, Chatel S, Despres A, Gros F, Kyndt F, Lecointe S, Lindenbaum P, Portero V, Violleau J, Gessler M, Tan HL, Roden DM, Christoffels VM, Le Marec H, Wilde AA, Probst V, Schott J-J, Dina C, Redon R. Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death. Nat Genet 2013;45: 1409. Abstract
Brune C, Burger M, Sawatzky A, Kösters T, Wübbeling F. Forward-backward EM-TV methods for Inverse Problems with Poisson noise. In: Burger M, Osher S. Level-Set and PDE-based Reconstruction Methods 2013;Springer: 71-142. Abstract
Burger M, Modersitzki J, Ruthotto L. A Hyperelastic Regularization Energy for Image Registration. SIAM J Sci Comput 2013;35: B132-B148. Abstract
Buther F, Ernst I, Hamill J, Eich HT, Schober O, Schafers M, Schafers KP. External radioactive markers for PET data-driven respiratory gating in positron emission tomography. Eur J Nucl Med Mol Imaging 2013;40: 602-614. Abstract
Dawood M, Gigengack F, Jiang X, Schäfers KP. A mass conservation-based optical flow method for cardiac motion correction in 3D-PET. Med Phys 2013;40: 012505. Abstract
Diepenbrock S, Hermann S, Schäfers M, Kuhlmann M, Hinrichs K. Comparative Visualization of Tracer Uptake in In Vivo Small Animal PET/CT Imaging of the Carotid Arteries. Comput Graph Forum 2013;32: 241-250. Abstract
Enzi B, Doering S, Faber C, Hinrichs J, Bahmer J, Northoff G. Reduced deactivation in reward circuitry and midline structures during emotion processing in borderline personality disorder. World J Biol Psychiatry 2013;14: 45-56. Abstract
Gigengack F, Ruthotto L, Jiang X, Modersitzki J, Burger M, Hermann S, Schäfers KP. Atlas-Based Whole-Body PET-CT Segmentation using a Passive Contour Distance. Lect Notes Comput Sc 2013;7766: 82-92. Abstract
Gottschlag H, Kösters T, Vernekohl D, Reygers K, Schäfers KP, Wübbeling F, Wessels JP. Towards Quantitative Image Reconstruction Using Monte-Carlo Simulations in Multi-Wire Proportional Chamber-Based Small Animal PET. IEEE Trans Nucl Sci 2013;60: 3343-3354. Abstract
Grabner A, Kentrup D, Edemir B, Sirin Y, Pavenstadt H, Schlatter E, Schober O, Schafers M, Schnockel U, Reuter S. PET with 18F-FDG-labeled T lymphocytes for diagnosis of acute rat renal allograft rejection. J Nucl Med 2013;54: 1147-1153. Abstract
Grabner A, Kentrup D, Schnockel U, Gabriels G, Schroter R, Pavenstadt H, Schober O, Schlatter E, Schafers M, Reuter S. Non-invasive imaging of acute allograft rejection after rat renal transplantation using 18F-FDG PET. J Vis Exp 2013: e4240. Abstract
Grabner A, Kentrup D, Schnöckel U, Schäfers M, Reuter S. Non-Invasive Diagnosis of Acute Renal Allograft Rejection - Special Focus on Gamma Scintigraphy and Positron Emission Tomography 2013: chapter 4. Abstract
Gutbrodt KL, Schliemann C, Giovannoni L, Frey K, Pabst T, Klapper W, Berdel WE, Neri D. Antibody-based delivery of interleukin-2 to neovasculature has potent activity against acute myeloid leukemia. Sci Transl Med 2013;5: 201ra118. Abstract
Hägerling R, Pollmann C, Andreas M, Schmidt C, Nurmi H, Adams RH, Alitalo K, Andresen V, Schulte-Merker S, Kiefer F. A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy. EMBO J 2013;32: 629-644. Abstract
Hahnenkamp A, Schäfers M, Bremer C, Höltke C. Design and Synthesis of Small-Molecule Fluorescent Photoprobes Targeted to Aminopeptdase N (APN/CD13) for Optical Imaging of Angiogenesis. Bioconjug Chem 2013;24: 1027-1038. Abstract
Hermann S, Pichler B, Kotzerke J. [Preclinical research Seal of approval translational medicine]. Nuklearmedizin 2013;52: N53-4. Abstract
Hoerr V, Nagelmann N, Nauerth A, Kuhlmann MT, Stypmann J, Faber C. Cardiac-respiratory self-gated cine ultra-short echo time (UTE) cardiovascular magnetic resonance for assessment of functional cardiac parameters at high magnetic fields. J Cardiovasc Magn Reson 2013;15: 59. Abstract
Holl K, Falck E, Kohler J, Schepmann D, Humpf H-U, Brust P, Wunsch B. Synthesis, characterization, and metabolism studies of fluspidine enantiomers. ChemMedChem 2013;8: 2047-2056. Abstract
Hugenberg V, Riemann B, Hermann S, Schober O, Schafers M, Szardenings K, Lebedev A, Gangadharmath U, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S. Inverse 1,2,3-triazole-1-yl-ethyl substituted hydroxamates as highly potent matrix metalloproteinase inhibitors: (radio)synthesis, in vitro and first in vivo evaluation. J Med Chem 2013;56: 6858-6870. Abstract
Jiang X, Dawood M, Gigengack F, Risse B, Schmid S, Tenbrinck D, Schäfers K. Biomedical imaging: A computer vision perspective. Lect Notes Comput Sc 2013;8047: 1-19. Abstract
Jiang X, Tenbrinck D. Region based contour detection by dynamic programming. Lect Notes Comput Sc 2013;8048: 152-159. Abstract
Junker A, Yamaguchi J, Itami K, Wunsch B. Synthesis of thiophene-based TAK-779 analogues by C-H arylation. J Org Chem 2013;78: 5579-5586. Abstract
Laakmann S, Fortmuller L, Piccini I, Grote-Wessels S, Schmitz W, Breves G, Kirchhof P, Fabritz L. Minimally invasive closed-chest ultrasound-guided substance delivery into the pericardial space in mice. Naunyn Schmiedebergs Arch Pharmacol 2013;386: 227-238. Abstract
Lenz P, Bettenworth D, Krausewitz P, Brückner M, Ketelhut S, von Bally G, Domagk D, Kemper B. Digital holographic microscopy quantifies the degree of inflammation in experimental colitis. Integr Biol (Camb). 2013;5: 624-630. Abstract
Lenz P, Roggel M, Domagk D. Double- vs single-balloon enteroscopy: single center experience with emphasis on procedural performance. Int J Colorectal Dis 2013;28: 1239-1246. Abstract
Limpachayaporn P, Riemann B, Kopka K, Schober O, Schäfers M, Haufe G. Influence of 4- or 5-substituents on the pyrrolidine ring of 5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin derivatives on their inhibitory activities towards caspases-3 and -7. Eur J Med Chem 2013;64C: 562-578. Abstract
Limpachayaporn P, Schäfers M, Schober O, Kopka K, Haufe G. Synthesis of new fluorinated, 2-substituted 5-pyrrolidinylsulfonyl isatin derivatives as caspase-3 and caspase-7 inhibitors: Nonradioactive counterparts of putative PET-compatible apoptosis imaging agents. Bioorg Med Chem 2013;21: 2025-2036. Abstract
Limpachayaporn P, Wagner S, Kopka K, Hermann S, Schäfers M, Haufe G. Synthesis, 18F-radiolabeling, and in vivo biodistribution studies of N-fluorohydroxybutyl isatin sulfonamides using positron emission tomography. J Med Chem 2013;56: 4509-4520. Abstract
Lindemann F, Laukamp K, Jacobs AH, Hinrichs K. Interactive Comparative Visualization of Multimodal Brain Tumor Segmentation Data. VMV13 2013: 105-112. Abstract
Neesse A, Hahnenkamp A, Griesmann H, Buchholz M, Hahn SA, Maghnouj A, Fendrich V, Ring J, Sipos B, Tuveson DA, Bremer C, Gress TM, Michl P. Claudin-4-targeted optical imaging detects pancreatic cancer and its precursor lesions. Gut 2013;62: 1034-1043. Abstract
Paul M, Wichter T, Gerss J, Arps V, Schulze-Bahr E, Robenek H, Breithardt G, Weissen-Plenz G. Connexin expression patterns in arrhythmogenic right ventricular cardiomyopathy. Am J Cardiol 2013;111: 1488-1495. Abstract
Persigehl T, Ring J, Budny T, Hahnenkamp A, Stoeppeler S, Schwartz LH, Spiegel H-U, Heindel W, Remmele S, Bremer C. Vessel Size Imaging (VSI) by Robust Magnetic Resonance (MR) Relaxometry: MR-VSI of Solid Tumors in Correlation with Immunohistology and Intravital Microscopy. Mol Imaging 2013;12: 1-11. Abstract
Pollmann C, Hägerling R, Andreas M, Kiefer F. Ultramikroskopische Darstellung von Lymphgefäßen während der Fötalentwicklung und im Erwachsenenstadium der Maus. LymphForsch 2013;17: 6-12.
Samol A, Wollmann C, Vahlhaus C, Gerss J, Bruns H-J, Breithardt G, Schulze-Bahr E, Wichter T, Paul M. T-wave integral: an electrocardiographic marker discriminating patients with arrhythmogenic right ventricular cardiomyopathy from patients with right ventricular outflow tract tachycardia. Europace 2013;15: 582-589. Abstract
Sawatzky A, Tenbrinck D, Jiang X, Burger M. A Variational Framework for Region-Based Segmentation Incorporating Physical Noise Models. J Math Imaging Vision 2013;47(3): 179-209. Abstract
Schinor B, Wibbeling B, Haufe G. Synthesis and pKa values of 2-(3- and 4-pentafluorosulfanylphenyl)-2-fluorocyclopropylamines. J Flourine Chem 2013: 102-109. Abstract
Schmid F, Höltke C, Parker D, Faber C. Boosting (19) F MRI-SNR efficient detection of paramagnetic contrast agents using ultrafast sequences. Magn Reson Med 2013;69: 1056-1062. Abstract
Schmid S, Jiang X, Schäfers K. High-precision lens distortion correction using smoothed thin plate splines. Lect Notes Comput Sc 2013;8048: 432-439. Abstract
Schwöppe C, Zerbst C, Fröhlich M, Schliemann C, Kessler T, Liersch R, Overkamp L, Holtmeier R, Stypmann J, Dreiling A, König S, Höltke C, Lücke M, Müller-Tidow C, Mesters RM, Berdel WE. Anticancer therapy by tumor vessel infarction with polyethylene glycol conjugated retargeted tissue factor. J Med Chem 2013;56: 2337-2347. Abstract
Stegger L, Schülke C, Wenning C, Rahbar K, Kies P, Schober O, Schäfers M. Cardiac PET/MRI. Curr Cardiovasc Imaging Rep 2013: 1-10. Abstract
Tenbrinck D, Jiang X. Discriminant Analysis based Level Set Segmentation for Ultrasound Imaging. Lect Notes Comput Sc 2013;8048: 144-151. Abstract
Tenbrinck D, Schmid S, Jiang X, Schäfers K, Stypmann J. Histogram-based Optical Flow for Motion Estimation in Ultrasound Imaging. J Math Imaging Vision 2013;47(1): 138-150.
Waldmann C, Schober O, Haufe G, Kopka K. A closer look at the bromine-lithium exchange with tert-butyllithium in an aryl sulfonamide synthesis. Org Lett 2013;15: 2954-2957. Abstract
Waschkau B, Faust A, Schäfers M, Bremer C. Performance of a new fluorescence-labeled MMP inhibitor to image tumor MMP activity in vivo in comparison to an MMP-activatable probe. Contrast Media Mol Imaging 2013;8: 1-11. Abstract
Wenning C, Lange PS, Schülke C, Vrachimis A, Mönnig G, Schober O, Eckardt L, Schafers M. Pulmonary vein isolation in patients with paroxysmal atrial fibrillation is associated with regional cardiac sympathetic denervation. EJNMMI Res 2013;3: 81. Abstract
Würslin C, Schmidt H, Martirosian P, Brendle C, Boss A, Schwenzer NF, Stegger L. Respiratory Motion Correction in Oncologic PET Using T1-Weighted MR Imaging on a Simultaneous Whole-Body PET/MR System. J Nucl Med 2013;54: 464-471. Abstract


Büther K, Compeer MG, De Mey JG, Schober O, Schäfers M, Bremer C, Riemann B, Höltke C. Assessment of Endothelin-A Receptor Expression in Subcutaneous and Orthotopic Thyroid Carcinoma Xenografts in Vivo Employing Optical Imaging Methods. Endocrinology 2012;153: 2907-2918. Abstract
Claesener M, Breyholz H-J, Hermann S, Faust A, Wagner S, Schober O, Schäfers M, Kopka K. Efficient synthesis of a fluorine-18 labeled biotin derivative. Nucl Med Biol 2012;39: 1189-1194. Abstract
Claesener M, Schober O, Wagner S, Kopka K. Radiosynthesis of a 68Ga labeled matrix metalloproteinase inhibitor as a potential probe for PET imaging. Int J Appl Radiat Is 2012;70: 1723–1728. Abstract
Compeer MG, Meens MJ, Hackeng TM, Neugebauer WA, Höltke C, De Mey JG. Agonist-Dependent Modulation of Arterial Endothelin(A) -Receptor Function. Br J Pharmacol 2012;166: 1833–1845. Abstract
Diepenbrock S, Ropinski T. From Imprecise User Input to Precise Vessel Segmentations. EG Visual Computing for Biology and Medicine 2012: 65-72.
Fabritz L, Fortmuller L, Yu TY, Paul M, Kirchhof P. Can preload-reducing therapy prevent disease progression in arrhythmogenic right ventricular cardiomyopathy? Experimental evidence and concept for a clinical trial. Prog Biophys Mol Biol 2012;110: 340-346. Abstract
Froese A, Breher SS, Waldeyer C, Schindler RF, Nikolaev VO, Rinne S, Wischmeyer E, Schlueter J, Becher J, Simrick S, Vauti F, Kuhtz J, Meister P, Kreissl S, Torlopp A, Liebig SK, Laakmann S, Muller TD, Neumann J, Stieber J, Ludwig A, Maier SK, Decher N, Arnold HH, Kirchhof P, Fabritz L, Brand T. Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice. J Clin Invest 2012;122: 1119-30. Abstract
Gigengack F, Ruthotto L, Burger M, Wolters C, Jiang X, Schäfers K. Motion Correction in Dual Gated Cardiac PET using Mass-Preserving Image Registration. IEEE Trans Med Imaging 2012;31: 698-712. Abstract
Gigengack F, Ruthotto L, Kösters T, Jiang X, Modersitzki J, Burger M, Hermann S, Schäfers KP. Atlas-Based Segmentation Using Passive Contours. IEEE NSS/MIC 2012: 3015-3016.
Gigengack F, Ruthotto L, Kösters T, Jiang X, Modersitzki J, Burger M, Wolters CH, Schäfers KP. Pipeline for Motion Correction in Dual Gated PET. IEEE NSS/MIC 2012: 2983-2984. Abstract
Hermann S, Starsichova A, Waschkau B, Kuhlmann M, Wenning C, Schober O, Schäfers M. Non-FDG imaging of atherosclerosis: Will imaging of MMPs assess plaque vulnerability?. J Nucl Cardiol 2012;19: 609-617. Abstract
Hischemoller A, Walter C, Weiler V, Hummel H, Thepen T, Huhn M, Barth S, Hoheisel W, Kohler K, Dimova-Landen D, Bremer C, Haase M, Waldeck J. Labeling of Anti-MUC-1 Binding Single Chain Fv Fragments to Surface Modified Upconversion Nanoparticles for an Initial in Vivo Molecular Imaging Proof of Principle Approach. Int J Mol Sci 2012;13: 4153-4167. Abstract
Hugenberg V, Breyholz H-J, Riemann B, Hermann S, Schober O, Schäfers M, Gangadharmath U, Mocharla V, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S. A new class of highly potent matrix metalloproteinase inhibitors based on triazole-substituted hydroxamates: (radio)synthesis and in vitro and first in vivo evaluation. J Med Chem 2012;55: 4714-4727. Abstract
Hugenberg V, Haufe G. Fluoro-Pummerer rearrangement and analogous reactions. J Fluorine Chem 2012;143: 238-262. Abstract
Kuhlmann MT, Cuhlmann S, Hoppe I, Krams R, Evans PC, Strijkers GJ, Nicolay K, Hermann S, Schäfers M. Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice. J Vis Exp 2012: 3308. Abstract
Paul M, Rahbar K, Gerss J, Kies P, Schober O, Schäfers K, Breithardt G, Schulze-Bahr E, Wichter T, Schäfers M. Microvascular dysfunction in nonfailing arrhythmogenic right ventricular cardiomyopathy. Eur J Nucl Med Mol Imaging 2012;39: 416-420. Abstract
Paulis LE, Geelen T, Kuhlmann MT, Coolen BF, Schäfers M, Nicolay K, Strijkers GJ. Distribution of lipid-based nanoparticles to infarcted myocardium with potential application for MRI-monitored drug delivery. J Control Release 2012;162: 276-285. Abstract
Rahbar K, Seifarth H, Schäfers M, Stegger L, Hoffmeier A, Spieker T, Tiemann K, Maintz D, Scheld HH, Schober O, Weckesser M. Differentiation of malignant and benign cardiac tumors using 18F-FDG PET/CT. J Nucl Med 2012;53: 856-863. Abstract
Riley G, Syeda F, Kirchhof P, Fabritz L. An introduction to murine models of atrial fibrillation. Front Physiol 2012;3: 296. Abstract
Ropinski T, Diepenbrock S, Bruckner S, Hinrichs K, Gröller E. Unified Boundary-Aware Texturing for Interactive Volume Rendering. IEEE T Vis Comput Gr 2012;18: 1942-1955. Abstract
Ruthotto L, Gigengack F, Burger M, Wolters CH, Jiang X, Schäfers KP, Modersitzki J. A Simplified Pipeline for Motion Correction in Dual Gated Cardiac PET. In: Bildverarbeitung für die Medizin 2012: 51-56. Abstract
Ruthotto L, Kugel H, Olesch J, Fischer B, Modersitzki J, Burger M, Wolters CH. Diffeomorphic susceptibility artifact correction of diffusion-weighted magnetic resonance images. Phys Med Biol 2012;57: 5715-5731. Abstract
Sabine A, Agalarov Y, Maby-El Hajjami H, Jaquet M, Hägerling R, Pollmann C,Bebber D, Pfenniger A, Miura N, Dormond O, Calmes JM, Adams RH, Mäkinen T, Kiefer F, Kwak BR, Petrova TV. Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation. Dev Cell 2012: 430-45. Abstract
Schrigten D, Breyholz HJ, Wagner S, Hermann S, Schober O, Schäfers M, Haufe G, Kopka K. A new generation of radiofluorinated pyrimidine-2,4,6-triones as MMP-targeted radiotracers for positron emission tomography. J Med Chem 2012: 223-232. Abstract
Schwenzer NF, Stegger L, Bisdas S, Schraml C, Kolb A, Boss A, Müller M, Reimold M, Ernemann U, Claussen CD, Pfannenberg C, Schmidt H. Simultaneous PET/MR imaging in a human brain PET/MR system in 50 patients - Current state of image quality. Eur J Radiol 2012;81: 3472-3478. Abstract
Stegger L, Martirosian P, Schwenzer N, Bisdas S, Kolb A, Pfannenberg C, Claussen CD, Pichler B, Schick F, Boss A. Simultaneous PET/MR imaging of the brain: feasibility of cerebral blood flow measurements with FAIR-TrueFISP arterial spin labeling MRI. Acta Radiol 2012;53: 1066-1072. Abstract
Strobel K, Hoerr V, Schmid F, Wachsmuth L, Löffler B, Faber C. Early detection of lung inflammation: Exploiting T1-effects of iron oxide particles using UTE MRI. Magn Reson Med 2012;68: 1924-1931. Abstract
Tekook MA, Fabritz L, Kirchhof P, Konig S, Muller FU, Schmitz W, Tal T, Zlotkin E, Kirchhefer U. Gene construction, expression and functional testing of an inotropic peptide from the venom of the black scorpion Hottentotta judaicus. Toxicon 2012;60: 1415-1427. Abstract
Tenbrinck D, Sawatzky A, Jiang X, Burger M, Haffner W, Willems P, Paul M, Stypmann J. Impact of Physical Noise Modeling on Image Segmentation in Echocardiography. EG VCBM 2012: 33-40. Abstract
Vrachimis A, Hermann S, Mathe D, Schober O, Schäfers M. Systematic evaluation of 99mTc-tetrofosmin versus 99mTc-sestamibi to study murine myocardial perfusion in small animal SPECT/CT. EJNMMI Res 2012;2: 21. Abstract
Wenning C, Stypmann J, Papavassilis P, Sindermann J, Schober O, Hoffmeier A, Scheld HH, Stegger L, Schäfers M. Left ventricular dilation and functional impairment assessed by gated SPECT are indicators of cardiac allograft vasculopathy in heart transplant recipients. J Heart Lung Transplant 2012;31: 719-728. Abstract
Zumhagen S, Stallmeyer B, Friedrich C, Eckardt L, Seebohm G, Schulze-Bahr E. Inherited long QT syndrome: clinical manifestation, genetic diagnostics, and therapy. Herzschrittmacherther Elektrophysiol 2012;23: 211-219. Abstract


Baumann A, Faust A, Law MP, Kuhlmann MT, Kopka K, Schäfers M, Karst U. Metabolite identification of a radiotracer by electrochemistry coupled to liquid chromatography with mass spectrometric and radioactivity detection. Anal Chem 2011;83: 5415-5421. Abstract
Benning M, Burger M. Error Estimates for General Fidelities. Electron Trans Numer Anal 2011;38: 44-68. Abstract
Boss A, Stegger L, Bisdas S, Kolb A, Schwenzer N, Pfister M, Claussen CD, Pichler BJ, Pfannenberg C. Feasibility of simultaneous PET/MR imaging in the head and upper neck area. Eur Radiol 2011;21: 1439-1446. Abstract
Di Marco GS, Reuter S, Kentrup D, Ting L, Ting L, Grabner A, Jacobi AM, Pavenstädt H, Baba HA, Tiemann K, Brand M. Cardioprotective effect of calcineurin inhibition in an animal model of renal disease. Eur Heart J 2011;32: 1935-1945. Abstract
Diepenbrock S, Praßni J S, Lindemann F, Bothe H W, Ropinski T. 2010 IEEE Visualization Contest Winner: Intreractive Planning for Brain Tumor Resections. IEEE Comput Graph 2011Abstract
Diepenbrock S, Ropinski T , Hinrichs K H. Context-Aware Volume Navigation. IEEE Pac Vis Symp 2011: 11-18. Abstract
Eisenblätter M, Persigehl T, Bremer C, Höltke C. Diagnostic Optical Imaging of Breast Cancer: From Animal Models to First-in-Men Studies. InTech 2011Abstract
Engbers R, Benning M, Heins P, Schäfers K, Burger M. Sparse recovery in myocardial blood flow quantification via PET. IEEE NSS/MIC 2011: 3742-3744.
Fabritz L, Herzig S. Can T-type calcium channels make a change of heart after myocardial infarction? Fiction or fact, and for better or for worse?. Cardiovasc Res 2011;91: 373-375. Abstract
Fabritz L, Hoogendijk MG, Scicluna BP, van Amersfoorth SCM, Fortmueller L, Wolf S, Laakmann S, Kreienkamp N, Piccini I, Breithardt G, Ruiz Noppinger P, Witt H, Ebnet K, Wichter T, Levkau B, Franke WW, Pieperhoff S, de Bakker JMT, Coronel R, Kirchhof P. Preload-reducing therapy prevents development of arrhythmogenic right ventricular cardiomyopathy in plakoglobin-deficient mice. J Am Coll Cardiol 2011;57: 740-750. Abstract
Fieseler M, Kosters T, Gigengack F, Braun H, Quick HH, Schäfers KP, Jiang X. Motion correction in PET-MRI: A human torso phantom study. IEEE NSS/MIC 2011: 3586-3588.
Ghanem A, Roll W, Bostani T, Dewald O, Fleischmann BK, Stypmann J, Nickenig G, Tiemann K. Cardiomyoplasty improves contractile reserve after myocardial injury in mice - functional and morphological investigations with reconstructive 3-dimensional echocardiography. Cell Transplant 2011;20: 1621-1628(8). Abstract
Gigengack F, Ruthotto L, Burger M, Wolters CH, Jiang X, Schäfers KP. Mass-preserving motion correction of PET: Displacement field vs spline transformation. IEEE NSS/MIC 2011: 3088-3090.
Gigengack F, Ruthotto L, Burger M, Wolters CH, Jiang X, Schäfers KP. Mass-preserving motion correction of dual gated cardiac PET. IEEE NSS/MIC 2011: 3206-3208.
Grabner A, Schnöckel U, Kentrup D, Schäfers M, Reuter S. Strategies for Non-Invasive Molecular Imaging of Acute Allograft Rejection by Gamma Scintigraphy and Positron Emission Tomography. Curr Radiopharm 2011;4(1): 10-23. Abstract
Hägerling R, Pollmann C, Kremer L, Andresen V, Kiefer F. Intravital two-photon microscopy of lymphatic vessel development and function using a transgenic Prox1 promoter-directed mOrange2 reporter mouse. Biochem Soc Trans 2011;39: 1674-1681. Abstract
Herrmann S, Fabritz L, Layh B, Kirchhof P, Ludwig A. Insights into sick sinus syndrome from an inducible mouse model. Cardiovasc Res 2011;90: 38-48. Abstract
Huntgeburth M, Tiemann K, Shahverdyan R, Schluter K-D, Schreckenberg R, Gross M-L, Modersheim S, Caglayan E, Muller-Ehmsen J, Ghanem A, Vantler M, Zimmermann WH, Bohm M, Rosenkranz S. Transforming growth factor beta oppositely regulates the hypertrophic and contractile response to beta-adrenergic stimulation in the heart. PLoS One 2011;6: e26628. Abstract
Kahr PC, Piccini I, Fabritz L, Greber B, Scholer H, Scheld HH, Hoffmeier A, Brown NA, Kirchhof P. Systematic analysis of gene expression differences between left and right atria in different mouse strains and in human atrial tissue. PLoS One 2011;6: e26389. Abstract
Kentrup D, Reuter S, Schnöckel U, Grabner A, Edemir B, Pavenstadt H, Schober O, Schäfers M, Schlatter E, Bussemaker E. Hydroxyfasudil-mediated inhibition of ROCK1 and ROCK2 improves kidney function in rat renal acute ischemia-reperfusion injury. PLoS One 2011;6: e26419. Abstract
Kies P, Paul M, Gerss J, Stegger L, Monnig G, Schober O, Wichter T, Schäfers M, Schulze-Bahr E. Impaired cardiac sympathetic innervation in symptomatic patients with long QT syndrome. Eur J Nucl Med Mol Imaging 2011;38: 1899-1907. Abstract
Kirchhof P, Kahr PC, Kaese S, Piccini I, Vokshi I, Scheld H-H, Rotering H, Fortmueller L, Laakmann S, Verheule S, Schotten U, Fabritz L, Brown NA. PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression. Circ Cardiovasc Genet 2011;4: 123-133. Abstract
Kösters T, Schäfers KP, Wübbeling F. EMRECON: An expectation maximization based image reconstruction framework for emission tomography data. IEEE NSS/MIC 2011: 4365-4368.
Lemoine MD, Duverger JE, Naud P, Chartier D, Qi XY, Comtois P, Fabritz L, Kirchhof P, Nattel S. Arrhythmogenic left atrial cellular electrophysiology in a murine genetic long QT syndrome model. Cardiovasc Res 2011;92: 67-74. Abstract
Michel K, Büther K, Law MP, Wagner S, Schober O, Hermann S, Schäfers M, Riemann B, Höltke C, Kopka K. Development and evaluation of endothelin-A receptor (radio)ligands for positron emission tomography. J Med Chem 2011;54: 939-948. Abstract
Milberg P, Pott C, Frommeyer G, Fink M, Ruhe M, Matsuda T, Baba A, Klocke R, Quang TH, Nikol S, Stypmann J, Osada N, Muller FU, Breithardt G, Noble D, Eckardt L. Acute inhibition of the Na(+)/Ca(2+) exchanger reduces proarrhythmia in an experimental model of chronic heart failure. Heart Rhythm 2011;9: 570-8. Abstract
Muller J, Brune C, Sawatzky A, Kosters T, Schäfers KP, Burger M. Reconstruction of short time PET scans using Bregman iterations. IEEE NSS/MIC 2011: 2383-2385.
Paul M, Meyborg M, Boknik P, Gergs U, Schmitz W, Breithardt G, Wichter T, Neumann J. Autonomic dysfunction in patients with brugada syndrome: further biochemical evidence of altered signaling pathways. Pacing Clin Electrophysiol 2011;34: 1147-1153. Abstract
Paul M, Stypmann J, Gerss J, Wirdeier S, Zumhagen S, Breithardt G, Schulze-Bahr E, Wichter T. Safety of endomyocardial biopsy in patients with arrhythmogenic right ventricular cardiomyopathy a study analyzing 161 diagnostic procedures. JACC Cardiovasc Interv 2011;4: 1142-1148. Abstract
Paul M, Wichter T, Kies P, Gerss J, Wollmann C, Rahbar K, Eckardt L, Breithardt G, Schober O, Schulze-Bahr E, Schäfers M. Cardiac Sympathetic Dysfunction in Genotyped Patients with Arrhythmogenic Right Ventricular Cardiomyopathy and Risk of Recurrent Ventricular Tachyarrhythmias. J Nucl Med 2011;52: 1559-65. Abstract
Remmele S, Ring J, Senegas J, Heindel W, Mesters RM, Bremer C, Persigehl T. Concurrent MR blood volume and vessel size estimation in tumors by robust and simultaneous DeltaR2 and DeltaR2* quantification. Magn Reson Med 2011;66: 144-153. Abstract
Sawatzky A, Tenbrinck D, Jiang X, Burger M. A Variational Framework for Region-Based Segmentation Incorporating Physical Noise Models. UCLA 2011;11Abstract
Schellmann M, Gorlatch S, Meiländer D, Kösters T, Schäfers K, Wübbeling F, Burger M. Parallel medical image reconstruction: from graphics processing units (GPU) to grids. J Supercomp 2011;52: 151-160. Abstract
Schmid S, Tenbrinck D, Jiang X, Schäfers K, Tiemann K, Stypmann J. Histogram-Based Optical Flow for Functional Imaging in Echocardiography. Lect Notes Comput Sc 2011;6854/2011: 477-485. Abstract
von Maltzahn G, Park J-H, Lin KY, Singh N, Schwöppe C, Mesters R, Berdel WE, Ruoslahti E, Sailor MJ, Bhatia SN. Nanoparticles that communicate in vivo to amplify tumour targeting. Nat Mater 2011;10: 545-552. Abstract
Wagner S, Faust A, Breyholz H-J, Schober O, Schäfers M, Kopka K. The MMP inhibitor (R)-2-(N-benzyl-4-(2-[18F]fluoroethoxy)phenylsulphonamido)-N-hydroxy-3-met hylbutanamide: Improved precursor synthesis and fully automated radiosynthesis. Appl Radiat Isot 2011;69: 862-868. Abstract
Wagner S, Hugenberg V, Breyholz HJ, Faust A, Schober O, Schäfers M, Kopka K. Highly potent matrix metalloproteinase inhibitors based on triazole-substituted hydroxamic acids: synthesis, in vitro evaluation and 18F-radiolabelling. J Label Compd Radiopharm 2011;54: 150.
Wenning C, Stegger D, Hermann S, Schober O, Schäfers M. F-18-FDG Imaging for Atherosclerotic Plaque Characterization. Curr Cardiovasc Imaging Rep 2011;4: 190-198. Abstract


Blana A, Kaese S, Fortmuller L, Laakmann S, Damke D, van Bragt K, Eckstein J, Piccini I, Kirchhefer U, Nattel S, Breithardt G, Carmeliet P, Carmeliet E, Schotten U, Verheule S, Kirchhof P, Fabritz L. Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability. Heart Rhythm 2010;7: 1862-1869. Abstract
Boss A, Bisdas S, Kolb A, Hofmann M, Ernemann U, Claussen CD, Pfannenberg C, Pichler BJ, Reimold M, Stegger L. Hybrid PET/MRI of intracranial masses: initial experiences and comparison to PET/CT. J Nucl Med 2010;51: 1198-1205. Abstract
Bovens S, Schulze Elfringhoff A, Kaptur M, Reinhardt D, Schäfers M, Lehr M. 1-(5-Carboxyindol-1-yl)propan-2-one Inhibitors of Human Cytosolic Phospholipase A(2)alpha: Effect of Substituents in Position 3 of the Indole Scaffold on Inhibitory Potency, Metabolic Stability, Solubility, and Bioavailability. J Med Chem 2010;53: 8298–8308. Abstract
Breyholz HJ, Wagner S, Faust A, Riemann B, Höltke C, Hermann S, Schober O, Schäfers M, Kopka K. Radiofluorinated pyrimidine-2,4,6-triones as molecular probes for noninvasive MMP-targeted imaging. ChemMedChem 2010;5: 777-789. Abstract
Buscher K, Judenhofer MS, Kuhlmann MT, Hermann S, Wehrl HF, Schäfers KP, Schäfers M, Pichler BJ, Stegger L. Isochronous assessment of cardiac metabolism and function in mice using hybrid PET/MRI. J Nucl Med 2010;51: 1277-1284. Abstract
Büther F, Ernst I, Dawood M, Kraxner P, Schäfers M, Schober O, Schäfers KP. Detection of respiratory tumour motion using intrinsic list mode-driven gating in positron emission tomography. Eur J Nucl Med Mol Imaging 2010;37: 2315-2327. Abstract
Dawood M, Brune C, Büther F, Jiang X, Burger M, Schober O, Schäfers M, Schäfers KP. A continuity equation based optical flow method for cardiac motion correction in 3 D PET data. Lect Notes Comput Sc 2010;6326: 88-97. Abstract
Dreischaluck J, Schwöppe C, Spieker T, Kessler T, Tiemann K, Liersch R, Schliemann C, Kreuter M, Kolkmeyer A, Hintelmann H, Mesters RM, Berdel WE. Vascular infarction by subcutaneous application of tissue factor targeted to tumor vessels with NGR-peptides: activity and toxicity profile. Int J Oncol 2010;37: 1389-1397. Abstract
Drews A, Bovens S, Roebrock K, Sunderkotter C, Reinhardt D, Schäfers M, van der Velde A, Schulze Elfringhoff A, Fabian J, Lehr M. 1-(5-carboxyindol-1-yl)propan-2-one inhibitors of human cytosolic phospholipase A(2)alpha with reduced lipophilicity: synthesis, biological activity, metabolic stability, solubility, bioavailability, and topical in vivo activity. J Med Chem 2010;53: 5165-5178. Abstract
Fabritz L, Damke D, Emmerich M, Kaufmann SG, Theis K, Blana A, Fortmuller L, Laakmann S, Hermann S, Aleynichenko E, Steinfurt J, Volkery D, Riemann B, Kirchhefer U, Franz MR, Breithardt G, Carmeliet E, Schäfers M, Maier SKG, Carmeliet P, Kirchhof P. Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3. Cardiovasc Res 2010;87: 60-72. Abstract
Gigengack F, Ruthotto L, Burger M, Wolters CH, Jiang X, Schäfers K. Motion correction of cardiac PET using mass-preserving registration. IEEE NSS/MIC 2010: 3317-3319.
Gottschlag H. Small animal positron emission tomography with multi-wire proportional counters 2010
Hugenberg V, Fröhlich R, Haufe G. Oxidative desulfurization-fluorination of thioethers Application for the synthesis of fluorinated nitrogen containing building blocks. Org Biomol Chem 2010;8: 5682-5691. Abstract
Hugenberg V, Haufe G. Facile Synthesis of a,a-Difluoroalkyl Aryl Thioethers and Their Oxidative Desulfurization-Fluorination to Trifluorides. J Fluorine Chem 2010;131: 942-950. Abstract
Hugenberg V, Wagner S, Kopka K, Schober O, Schäfers M, Haufe G. Synthesis of geminal difluorides by oxidative desulfurization-difluorination of alkyl aryl thioethers with halonium electrophiles in the presence of fluorinating reagents and its application for 18F-radiolabeling. J Org Chem 2010;75: 6086-6095. Abstract
Kösters T. Derivation and analysis of scatter correction algorithms for quantitative positron emission tomography 2010Abstract
Larmann J, Frenzel T, Hahnenkamp A, Herzog C, Lorenz A, Steinbicker AU, Calmer S, Harendza T, Schmitz M, Echtermeyer F, Hildebrand R, Bremer C, Theilmeier G. In vivo fluorescence-mediated tomography for quantification of urokinase receptor-dependent leukocyte trafficking in inflammation. Anesthesiology 2010;113: 610-618. Abstract
Law MP, Schäfers K, Kopka K, Wagner S, Schober O, Schäfers M. Molecular imaging of cardiac sympathetic innervation by 11C-mHED and PET: from man to mouse?. J Nucl Med 2010;51: 1269-1276. Abstract
Law MP, Wagner S, Kopka K, Renner C, Pike VW, Schober O, Schäfers M. Preclinical evaluation of an 18F-labelled beta1-adrenoceptor selective radioligand based on ICI 89,406. Nucl Med Biol 2010;37: 517-526. Abstract
Lindemann F, Ropinski T. Advanced Light Material Interaction for Direct Volume Rendering. IEEE VG 2010: 101-108.
Mensmann J, Ropinski T, Hinrichs K H. An Advanced Volume Raycasting Technique using GPU Stream Processing. GRAPP 2010: 190-198.
Mensmann J, Ropinski T, Hinrichs K H. A GPU-Supported Lossless Compression Scheme for Rendering Time-Varying Volume Data. IEEE VG 2010: 109-116.
Meß C, Ropinski T. Efficient Acquisition and Clustering of Local Histograms for Representing Voxel Neighborhoods. IEEE VG 2010: 117-124.
Meyer-Spradow J, Ropinski T, Mensmann J, Hinrichs K. Interactive Design and Debugging of GPU-based Volume Visualizations. GRAPP 2010: 239-245.
Praßni J, S, Ropinski T, Mensmann J, Hinrichs K H. Shape-based Transfer Functions for Volume Visualization. IEEE Pac Vis Symp 2010: 9-16.
Prassni J-S, Ropinski T, Hinrichs K. Uncertainty-aware guided volume segmentation. IEEE Trans Vis Comput Graph 2010;16: 1358-1365. Abstract
Range FT, Wenning C, Rahbar K, Schober O Schäfers M. Nuclear medicine imaging of the heart and large vessels - State of the art. Zeitschrift für Herz-, Thorax- und Gefäßchirurgie 2010;24: 169-184. Abstract
Reuter S, Schnöckel U, Edemir B, Schröter R, Kentrup D, Pavenstädt H, Schober O, Schlatter E, Gabriels G, Schäfers M. Potential of noninvasive serial assessment of acute renal allograft rejection by 18F-FDG PET to monitor treatment efficiency. J Nucl Med 2010;51: 1644-1652. Abstract
Ropinski T, Döring C, Rezk-Salama C. Interactive Volumetric Lighting Simulating Scattering and Shadowing. IEEE Pac Vis Symp 2010: 169-176.
Schäfers M, Schober O, Hermann S. Matrix-metalloproteinases as imaging targets for inflammatory activity in atherosclerotic plaques. J Nucl Med 2010;51: 663-666. Abstract
Schnöckel U, Hermann S, Stegger L, Law M, Kuhlmann M, Schober O, Schäfers K, Schäfers M. Small-animal PET: a promising, non-invasive tool in pre-clinical research. Eur J Pharm Biopharm 2010;74: 50-54. Abstract
Schwöppe C, Kessler T, Persigehl T, Liersch R, Hintelmann H, Dreischaluck J, Ring J, Bremer C, Heindel W, Mesters RM, Berdel WE. Tissue-factor fusion proteins induce occlusion of tumor vessels. Thromb Res 2010;125 Suppl 2: S143-50. Abstract
Tenbrinck D, Dawood M, Gigengack F, Fieseler M, Jiang X, Schäfers K. Motion correction in Positron Emission Tomography considering Partial Volume Effects in optical flow estimation. IEEE ISBI 2010: 1233-1236. Abstract
Tsotsalas MM, Kopka K, Luppi G, Wagner S, Law MP, Schäfers M, De Cola L. Encapsulating (111)In in nanocontainers for scintigraphic imaging: synthesis, characterization, and in vivo biodistribution. ACS Nano 2010;4: 342-348. Abstract


Benning M, Burger M. Error estimation for variational models with non-Gaussian noise 2009Abstract
Bunck AC, Engelen MA, Schnackenburg B, Furkert J, Bremer C, Heindel W, Stypmann J, Maintz D. Feasibility of functional cardiac MR imaging in mice using a clinical 3 Tesla whole body scanner. Invest Radiol 2009;44: 749-756. Abstract
Büther F, Dawood M, Stegger L, Wübbeling F, Schäfers M, Schober O, Schäfers KP. List mode-driven cardiac and respiratory gating in PET. J Nucl Med 2009;50: 674-681. Abstract
Dawood M, Büther F, Stegger L, Jiang X, Schober O, Schäfers M, Schäfers KP. Optimal number of respiratory gates in positron emission tomography: a cardiac patient study. Med Phys 2009;36: 1775-1784. Abstract
Faust A, Hermann S, Wagner S, Haufe G, Schober O, Schäfers M, Kopka K. Molecular imaging of apoptosis in vivo with scintigraphic and optical biomarkers - a status report. Anticancer Agents Med Chem 2009;9: 968-985. Abstract
Faust A, Waschkau B, Waldeck J, Höltke C, Breyholz H-J, Wagner S, Kopka K, Schober O, Heindel W, Schäfers M, Bremer C. Synthesis and evaluation of a novel hydroxamate based fluorescent photoprobe for imaging of matrix metalloproteinases. Bioconjug Chem 2009;20: 904-912. Abstract
Ghanema A, Steingen C, Brenig F, Funcke F, Bai ZY, Hall C, Chin CT, Nickenig G, Bloch W, Tiemann K. Focused ultrasound-induced stimulation of microbubbles augments site-targeted engraftment of mesenchymal stem cells after acute myocardial infarction. J Mol Cell Cardiol 2009;47: 411-418. Abstract
Höltke C, Faust A, Breyholz H-J, Kopka K, Schober O, Riemann B, Bremer C, Schäfers M, Wagner S. Non-invasive approaches to visualize the endothelin axis in vivo using state-of-the-art molecular imaging modalities. Mini Rev Med Chem 2009;9: 1580-1595. Abstract
Höltke C, Law MP, Wagner S, Kopka K, Faust A, Breyholz H-J, Schober O, Bremer C, Riemann B, Schäfers M. PET-compatible endothelin receptor radioligands: synthesis and first in vitro and in vivo studies. Bioorg Med Chem 2009;17: 7197-7208. Abstract
Höltke C, Waldeck J, Kopka K, Heindel W, Schober O, Schäfers M, Bremer C. Biodistribution of a nonpeptidic fluorescent endothelin A receptor imaging probe. Mol Imaging 2009;8: 27-34. Abstract
Hugenberg V, Haufe G. Oxidative Desulfurization-Difluorination of Alkyl Aryl Thioethers: Synthesis of ω-Substituted 1,1-Difluoroalkanes. Synlett 2009: 106-108. Abstract
Kato K, Schober O, Ikeda M, Schäfers M, Ishigaki T, Kies P, Naganawa S, Stegger L. Evaluation and comparison of 11C-choline uptake and calcification in aortic and common carotid arterial walls with combined PET/CT. Eur J Nucl Med Mol Imaging 2009;36: 1622-1628. Abstract
Kuhn M, Volker K, Schwarz K, Carbajo-Lozoya J, Flogel U, Jacoby C, Stypmann J, van Eickels M, Gambaryan S, Hartmann M, Werner M, Wieland T, Schrader J, Baba HA. The natriuretic peptide/guanylyl cyclase - a system functions as a stress-responsive regulator of angiogenesis in mice. J Clin Invest 2009;119: 2019-2030. Abstract
Meyer-Spradow J, Ropinski T, Mensmann J, Hinrichs K H. A Rapid-Prototyping Environment for Ray-Casting-Based Volume Visualizations. IEEE Comput Graph 2009: 6-13. Abstract
Paul M, Zumhagen S, Stallmeyer B, Koopmann M, Spieker T, Schulze-Bahr E. Genes causing inherited forms of cardiomyopathies A current compendium. Herz 2009;34: 98-109. Abstract
Podichetty AK, Faust A, Kopka K, Wagner S, Schober O, Schäfers M, Haufe G. Fluorinated isatin derivatives Part 1: synthesis of new N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatins as potent caspase-3 and -7 inhibitors. Bioorg Med Chem 2009;17: 2680-2688. Abstract
Podichetty AK, Wagner S, Faust A, Schäfers M, Schober O, Kopka K, Haufe G. Fluorinated isatin derivatives Part 3 New side-chain fluoro-functionalized pyrrolidinyl sulfonyl isatins as potent caspase-3 and -7 inhibitors. Future Med Chem 2009;1: 969-989. Abstract
Podichetty AK, Wagner S, Kopka K, Schröer S Faust A Schäfers M, Schober O, Haufe G. New N-Substituted 5-Pyrrolidinylsulfonyl Isatins as Potential Tools for Imaging of Caspases in Apoptosis by Positron Emission Tomography. J Med Chem 2009;52: 3484-3495.
Podichetty AK, Wagner S, Schroer S, Faust A, Schäfers M, Schober O, Kopka K, Haufe G. Fluorinated isatin derivatives Part 2 New N-substituted 5-pyrrolidinylsulfonyl isatins as potential tools for molecular imaging of caspases in apoptosis. J.Med.Chem. 2009;52: 3484-3495. Abstract
Praßni J S, Ropinski T, Hinrichs K H. Efficient Boundary Detection and Transfer Function Generation in Direct Volume Rendering. VMV09 2009: 285-294.
Range FT, Paul M, Schäfers KP, Acil T, Kies P, Hermann S, Schober O, Breithardt G, Wichter T, Schäfers MA. Myocardial perfusion in nonischemic dilated cardiomyopathy with and without atrial fibrillation. J Nucl Med 2009;50: 390-396. Abstract
Reuter S, Bangen P, Edemir B, Hillebrand U, Pavenstädt H, Heidenreich S, Lang D. The HSP72 stress response of monocytes from patients on haemodialysis is impaired. Nephrol Dial Transplant 2009;24: 2838-2846. Abstract
Reuter S, Schnöckel U, Schroter R, Schober O, Pavenstädt H, Schäfers M, Gabriels G, Schlatter E. Non-invasive imaging of acute renal allograft rejection in rats using small animal F-FDG-PET. PLoS One 2009;4: e5296. Abstract
Ropinski T, Hermann S, Reich R, Schäfers M, Hinrichs K. Multimodal vessel visualization of mouse aorta PET/CT scans. IEEE Trans Vis Comput Graph 2009;15: 1515-1522. Abstract
Ropinski T, Viola I, Biermann M, Hauser H, Hinrichs K. Multimodal Visualization with Interactive Closeups. IEEE Pac Vis Symp 2009: 17-24.
Sawatzky A, Brune C, Müller J, Burger M. Total Variation Processing of Images with Poisson Statistics. Lect Notes Comput Sc 2009;5702: 533-540. Abstract
Schellmann M, Gorlatch S, Meiländer D, Kösters T, Schäfers K, Wübbeling F, Burger M. Parallel Medical Image Reconstruction: From Graphics Processors to Grids. Lect Notes Comput Sc 2009;5698: 457-473. Abstract
Stegger L, Heijman E, Schäfers KP, Nicolay K, Schäfers MA, Strijkers GJ. Quantification of left ventricular volumes and ejection fraction in mice using PET, compared with MRI. J Nucl Med 2009;50: 132-138. Abstract
Stypmann J, Engelen MA, Troatz C, Rothenburger M, Eckardt L, Tiemann K. Echocardiographic assessment of global left ventricular function in mice. Lab Anim 2009;43: 127-137. Abstract
Wagner S, Breyholz H-J, Höltke C, Faust A, Schober O, Schäfers M, Kopka K. A new 18F-labelled derivative of the MMP inhibitor CGS 27023A for PET: radiosynthesis and initial small-animal PET studies. Appl Radiat Isot 2009;67: 606-610. Abstract
Wagner S, Breyholz H, Schäfers M, Schober O, Kopka K. 18F-Labeled pyrimidine-2,4,6-triones as potential probes for imaging activated MMPS. J Labelled Comp Radiopharm 2009;52: S40-S40.
Waldeyer C, Fabritz L, Fortmueller L, Gerss J, Damke D, Blana A, Laakmann S, Kreienkamp N, Volkery D, Breithardt G, Kirchhof P. Regional, age-dependent, and genotype-dependent differences in ventricular action potential duration and activation time in 410 Langendorff-perfused mouse hearts. Basic Res Cardiol 2009;104: 523-533. Abstract


Benning M, Kösters M, Wübbeling F, Schäfers K, Burger M. A nonlinear variational method for improved quantification of myocardial blood flow using dynamic H215O pET. IEEE NSS 2008: 4472-4477.
Dawood M, Büther F, Jiang X, Schäfers KP. Respiratory motion correction in 3-D PET data with advanced optical flow algorithms. IEEE Trans.Med.Imaging 2008;27: 1164-1175. Abstract
Dobrowolski R, Sasse P, Schrickel JW, Watkins M, Kim J-S, Rackauskas M, Troatz C, Ghanem A, Tiemann K, Degen J, Bukauskas FF, Civitelli R, Lewalter T, Fleischmann BK, Willecke K. The conditional connexin43G138R mouse mutant represents a new model of hereditary oculodentodigital dysplasia in humans. Hum Mol Genet 2008;17: 539-554. Abstract
Faust A, Waschkau B, Waldeck J, Höltke C, Breyholz H-J, Wagner S, Kopka K, Heindel W, Schäfers M, Bremer C. Synthesis and evaluation of a novel fluorescent photoprobe for imaging matrix metalloproteinases. Bioconjug Chem 2008;19: 1001-1008. Abstract
Ghanem A, Troatz C, Elhafi N, Dewald O, Heeschen C, Nickenig G, Stypmann J, Tiemann K. Quantitation of myocardial borderzone using reconstructive 3-D echocardiography after chronic infarction in rats: incremental value of low-dose dobutamine. Ultrasound Med Biol 2008;34: 559-566. Abstract
Grote-Wessels S, Baba HA, Boknik P, El-Armouche A, Fabritz L, Gillmann H-J, Kucerova D, Matus M, Muller FU, Neumann J, Schmitz M, Stumpel F, Theilmeier G, Wohlschlaeger J, Schmitz W, Kirchhefer U. Inhibition of protein phosphatase 1 by inhibitor-2 exacerbates progression of cardiac failure in a model with pressure overload. Cardiovasc Res 2008;79: 464-471. Abstract
Hoefler T, Schellmann M, Gorlatch S, Lumsdaine A. Communication Optimization for Medical Image Reconstruction Algorithms. Lect Notes Comput Sc 2008;5205: 75-83.
Kopka K, Schober O, Wagner S. (18)F-labelled cardiac PET tracers: selected probes for the molecular imaging of transporters, receptors and proteases. Basic Res Cardiol 2008;103: 131-143. Abstract
Law MP, Wagner S, Kopka K, Pike VW, Schober O, Schäfers M. Are [O-methyl-11C]derivatives of ICI 89,406 beta1-adrenoceptor selective radioligands suitable for PET?. Eur J Nucl Med Mol Imaging 2008;35: 174-185. Abstract
Levkau B, Schäfers M, Wohlschlaeger J, von Wnuck Lipinski K, Keul P, Hermann S, Kawaguchi N, Kirchhof P, Fabritz L, Stypmann J, Stegger L, Flogel U, Schrader J, Fischer JW, Hsieh P, Ou YL, Mehrhof F, Tiemann K, Ghanem A, Matus M, Neumann J, Heusch G, Schmid KW, Conway EM, Baba HA. Survivin determines cardiac function by controlling total cardiomyocyte number. Circulation 2008;117: 1583-1593. Abstract
Makita N, Behr E, Shimizu W, Horie M, Sunami A, Crotti L, Schulze-Bahr E, Fukuhara S, Mochizuki N, Makiyama T, Itoh H, Christiansen M, McKeown P, Miyamoto K, Kamakura S, Tsutsui H, Schwartz PJ, George ALJ, Roden DM. The E1784K mutation in SCN5A is associated with mixed clinical phenotype of type 3 long QT syndrome. J Clin Invest 2008;118: 2219-2229. Abstract
Mensmann J, Ropinski T, Hinrichs K. Accelerating Volume Raycasting using Occlusion Frustums. IEEE/EG 2008: 147-154.
Mensmann J, Ropinski T, Hinrichs K. Interactive Cutting Operations for Generating Anatomical Illustrations from Volumetric Data Sets. Journal WSCG 2008: 89-96.
Meyer-Spradow J, Stegger L, Doring C, Ropinski T, Hinrichs K. Glyph-based SPECT visualization for the diagnosis of coronary artery disease. IEEE Trans Vis Comput Graph 2008;14: 1499-1506. Abstract
Riemann B, Schäfers KP, Schober O, Schäfers M. Small animal PET in preclinical studies: opportunities and challenges. Q J Nucl Med Mol Imaging 2008;52: 215-221.
Ropinski T, Kasten J, Hinrichs K. Efficient Shadows for GPU-based Volume Raycasting. WSCG 2008: 17-24.
Ropinski T, Meyer-Spradow J, Diepenbrock S, Mensmann J, Hinrichs K. Interactive Volume Rendering with Dynamic Ambient Occlusion and Color Bleeding. Comput Graph Forum 2008: 567-576.
Ropinski T, Petkov B, Fabritz B, Hinrichs K. Interactive Reconstruction and Visualization of Dynamic 3D Ultrasound Data Sets. GRAPP 2008: 308-315.
Ropinski T, Praßni J S, Steinicke F, Hinrichs K H. Stroke-Based Transfer Function Design. IEEE/EG Volume and Point-Based Graphics 2008: 41-48.
Schafers KP, Stegger L. Combined imaging of molecular function and morphology with PET/CT and SPECT/CT: image fusion and motion correction. Basic Res Cardiol 2008;103: 191-199. Abstract
Schellmann M, Vording J, Gorlatch S. Systematic Parallelization of Medical Image Reconstruction for Graphics Hardware. Lect Notes Comput Sc 2008;5168: 811-821.
Schellmann M, Vording J, Gorlatch S, Meilander D. Cost-effective medical image reconstruction: from clusters to graphics processing units. ACM 2008: 283-292.
Stelljes M, Hermann S, Albring J, Kohler G, Loffler M, Franzius C, Poremba C, Schlosser C, Volkmann S, Opitz C, Bremer C, Kucharzik T, Silling G, Schober O, Berdel WE, Schäfers M, Kienast J. Clinical molecular imaging in intestinal graft-versus-host disease: mapping of disease activity, prediction, and monitoring of treatment efficiency by positron emission tomography. Blood 2008;111: 2909-2918. Abstract
Tsotsalas M, Busby M, Gianolio E, Aime S, De Cola L. Functionalized nanocontainers as dual magnetic and optical probes for molecular imaging applications. Chem Mater 2008;20: 5888-5893.
von Wallbrunn A, Waldeck J, Höltke C, Zuhlsdorf M, Mesters R, Heindel W, Schäfers M, Bremer C. In vivo optical imaging of CD13/APN-expression in tumor xenografts. J Biomed Opt 2008;13: 011007. Abstract
Waldeck J, Hager F, Höltke C, Lanckohr C, von Wallbrunn A, Torsello G, Heindel W, Theilmeier G, Schäfers M, Bremer C. Fluorescence reflectance imaging of macrophage-rich atherosclerotic plaques using an alphavbeta3 integrin-targeted fluorochrome. J Nucl Med 2008;49: 1845-1851. Abstract
Wall A, Persigehl T, Hauff P, Licha K, Schirner M, Muller S, von Wallbrunn A, Matuszewski L, Heindel W, Bremer C. Differentiation of angiogenic burden in human cancer xenografts using a perfusion-type optical contrast agent (SIDAG). Breast Cancer Res 2008;10: R23. Abstract


Breyholz HJ, Wagner S, Levkau B, Schober O, Schäfers M, Kopka K. A 18F-radiolabeled analogue of CGS 27023A as a potential agent for assessment of matrix-metalloproteinase activity in vivo. Q J Nucl Med Mol Imaging 2007;51: 24-32. Abstract
Büther F, Stegger L, Dawood M, Range F, Schäfers M, Fischbach R, Wichter T, Schober O, Schäfers KP. Effective methods to correct contrast agent-induced errors in PET quantification in cardiac PET/CT. J Nucl Med 2007;48: 1060-1068. Abstract
Dawood M, Büther F, Lang N, Schober O, Schäfers KP. Respiratory gating in positron emission tomography: a quantitative comparison of different gating schemes. Med Phys 2007;34: 3067-3076. Abstract
Dawood M, Fieseler M, Büther F, Jiang X, Schäfers KP. A Multi-resolution Optical Flow Based Approach to Respiratory Motion Correction in 3D PET/CT Images. Lect Notes Comput Sc 2007: 314-322. Abstract
Faust A, Wagner S, Law MP, Hermann S, Schnöckel U, Keul P, Schober O, Schäfers M, Levkau B, Kopka K. The nonpeptidyl caspase binding radioligand (S)-1-(4-(2-[18F]Fluoroethoxy)-benzyl)-5-[1-(2-methoxymethylpyrrolidinyl)s ulfonyl]isatin ([18F]CbR) as potential positron emission tomography-compatible apoptosis imaging agent. Q J Nucl Med Mol Imaging 2007;51: 67-73. Abstract
Fischbach R, Juergens KU, Ozgun M, Maintz D, Grude M, Seifarth H, Heindel W, Wichter T. Assessment of regional left ventricular function with multidetector-row computed tomography versus magnetic resonance imaging. Eur Radiol 2007;17: 1009-1017. Abstract
Hartung D, Schäfers M, Fujimoto S, Levkau B, Narula N, Kopka K, Virmani R, Reutelingsperger C, Hofstra L, Kolodgie F D, Petrov A, Narula J. Targeting of matrix metalloproteinase activation for noninvasive detection of vulnerable atherosclerotic lesions. Eur J Nucl Med Mol Imaging 2007;34: 1-8.
Höltke C, von Wallbrunn A, Kopka K, Schober O, Heindel W, Schäfers M, Bremer C. A fluorescent photoprobe for the imaging of endothelin receptors. Bioconjug Chem 2007;18: 685-694. Abstract
Höltke C, Wagner S, Breyholz HJ, Faust A, Law MP, Schäfers M, Kopka K. Developement, synthesis and in vitro evaluation of novel et-a receptor pet-radioligands based on pd 156707. J Labelled Comp Radiopharm 2007;50: 258.
Keul P, Tolle M, Lucke S, von Wnuck Lipinski K, Heusch G, Schuchardt M, van der Giet M, Levkau B. The sphingosine-1-phosphate analogue FTY720 reduces atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2007;27: 607-613. Abstract
Kirchhof P, Klimas J, Fabritz L, Zwiener M, Jones LR, Schäfers M, Hermann S, Boknik P, Schmitz W, Breithardt G, Kirchhefer U, Neumann J. Stress and high heart rate provoke ventricular tachycardia in mice expressing triadin. J Mol Cell Cardiol 2007;42: 962-971. Abstract
Kopka K, Breyholz H J, Wagner S, Brandau W, Hermann S, Schober O, Levkau B, Bremcer C, Schäfers M. Radioiodinated pyrimidine-2,4,6-triones as model probes for the in vivo molecular imaging of activated mmps. J Labelled Comp Radiopharm 2007;50: 310.
Lang N, Hermann S, Hold S, Mienkina M, Stegger L, Stypmann J, Schober O, Schäfers M, Schäfers KP, Schmitz G. Hybrid 3D Sono/PET in a mouse. Eur J Nucl Med Mol Imaging 2007;34: 1706-1707. Abstract
Meyer-Spradow J, Ropinski T, Hinrichs K. Supporting Depth and Motion Perception in Medical Volume Data. Math Visual 2007: 121-133.
Popovic Z, Otter M, Calzaferri G, De Cola L. Self-assembling living systems with functional nanomaterials. Angew Chem Int Ed Engl 2007;46: 6188-6191.
Ropinski T, Praßni J S, Roters J, Hinrichs K. Internal Labels as Shape Cues for Medical Illustration. VMV 2007: 203-212.
Ropinski T, Specht M, Meyer-Spradow J, Hinrichs K, Preim B. Surface Glyphs for Visualizing Multimodal Volume Data. VMV 2007: 3-12.
Schäfers M. Molekulare kardiovaskuläre Bildgebung. Nuklearmediziner 2007;30: 57-63. Abstract
Schellmann M, Bohm D, Wichmann S, Gorlatch S. Towards a grid system for medical image reconstruction. IEEE NSS 2007: 3019-3025.
Schellmann M, Gorlatch S. Comparison of Two Decomposition Strategies for Parallelizing the 3D List-Mode OSEM Algorithm 2007: 37-40.
Stegger L, Lipke CSA, Kies P, Nowak B, Schober O, Buell U, Schäfers M, Schaefer WM. Quantification of left ventricular volumes and ejection fraction from gated 99mTc-MIBI SPECT: validation of an elastic surface model approach in comparison to cardiac magnetic resonance imaging, 4D-MSPECT and QGS. Eur J Nucl Med Mol Imaging 2007;34: 900-909. Abstract
Stegger L, Schäfers K, Kopka K, Wagner S, Hermann S, Kies P, Law M, Schober O, Schäfers M. Molecular cardiovascular imaging using scintigraphic methods. Eur Radiol 2007;17: 1422-1432. Abstract
Stypmann J. Doppler ultrasound in mice. Echocardiography 2007;24: 97-112. Abstract
Stypmann J, Engelen MA, Orwat S, Bilbilis K, Rothenburger M, Eckardt L, Haverkamp W, Horst J, Dworniczak B, Pennekamp P. Cardiovascular characterization of Pkd2(+/LacZ) mice, an animal model for the autosomal dominant polycystic kidney disease type 2 (ADPKD2). Int J Cardiol 2007;120: 158-166. Abstract
von Wallbrunn A, Höltke C, Zuhlsdorf M, Heindel W, Schäfers M, Bremer C. In vivo imaging of integrin alpha v beta 3 expression using fluorescence-mediated tomography. Eur J Nucl Med Mol Imaging 2007;34: 745-754. Abstract
Wagner S, Breyholz H-J, Law MP, Faust A, Höltke C, Schroer S, Haufe G, Levkau B, Schober O, Schäfers M, Kopka K. Novel fluorinated derivatives of the broad-spectrum MMP inhibitors N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](benzyl)- and (3-picolyl)-amino]-3-methyl-butanamide as potential tools for the molecular imaging of activated MMPs with PET. J Med Chem 2007;50: 5752-5764. Abstract
Wagner S, Breyholz HJ, Law MP, Faust A, Hoeltke C, Schober O, Schäfers M, Kopka K. Fluorinated derivatives of the potent matrix metalloproteinase inhibitors CGS 25966 and CGS 27023A: (Radio)syntheses and in vitro evaluation. J Label Compd Radiopharm 2007;50: 62.
Walter DH, Rochwalsky U, Reinhold J, Seeger F, Aicher A, Urbich C, Spyridopoulos I, Chun J, Brinkmann V, Keul P, Levkau B, Zeiher AM, Dimmeler S, Haendeler J. Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor. Arterioscler Thromb Vasc Biol 2007;27: 275-282. Abstract
Wedekind H, Schulze-Bahr E, Debus V, Breithardt G, Brinkmann B, Bajanowski T. Cardiac arrhythmias and sudden death in infancy: implication for the medicolegal investigation. Int J Legal Med 2007;121: 245-257. Abstract


Choe C-un, Schulze-Bahr E, Neu A, Xu J, Zhu ZI, Sauter K, Bahring R, Priori S, Guicheney P, Monnig G, Neapolitano C, Heidemann J, Clancy CE, Pongs O, Isbrandt D. C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon. Hum Mol Genet 2006;15: 2888-2902. Abstract
Dawood M, Büther F, Lang N, Jiang X, Schäfers KP. Transforming Static CT in Gated PET/CT Studies to Multiple Respiratory Phases. ICPR 2006: 1026-1029. Abstract
Dawood M, Lang N, Jiang X, Schäfers KP. Lung motion correction on respiratory gated 3-D PET/CT images. IEEE Trans Med Imaging 2006;25: 476-485. Abstract
Kirchhof P, Fabritz L, Zwiener M, Witt H, Schäfers M, Zellerhoff S, Paul M, Athai T, Hiller K-H, Baba HA, Breithardt G, Ruiz P, Wichter T, Levkau B. Age- and training-dependent development of arrhythmogenic right ventricular cardiomyopathy in heterozygous plakoglobin-deficient mice. Circulation 2006;114: 1799-1806. Abstract
Kopka K, Faust A, Keul P, Wagner S, Breyholz H-J, Höltke C, Schober O, Schäfers M, Levkau B. 5-pyrrolidinylsulfonyl isatins as a potential tool for the molecular imaging of caspases in apoptosis. J Med Chem 2006;49: 6704-6715. Abstract
Meyer-Spradow J, Ropinski T, Vahrenhold J, Hinrichs K. Illustrating Dynamics of Time-Varying Volume Datasets in Static Images. VMV 2006: 333-340.
Ropinski T, Meyer-Spradow J, Steinicke F, Hinrichs K H. Design of a User-Oriented Application for the Exploration of Medical Datasets. Springer E&I Journal, Special Edition on New Computing in Medical Informatics & Health Care 2006: 131-134. Abstract
Ropinski T, Steinicke F, Hinrichs K. Visually Supporting Depth Perception in Angiography Imaging. Smart Graphics 2006: 93-104.
Schäfers KP, Lang N, Stegger L, Schober O, Schäfers M. Gated listmode acquisition with the quadHIDAC animal PET to image mouse hearts. Z Med Phys 2006;16: 60-66. Abstract
Schellmann M, Kösters T, Gorlatch S. Parallelization and Runtime Prediction of the ListMode OSEM Algorithm for 3D PET Reconstruction. IEEE NSS 2006: 2190-2195.
Schulze-Bahr E. Arrhythmia Predisposition: Between Rare Disease Paradigms and Common Ion Channel Gene Variants. J Am Coll Cardiol 2006;48: A67-A78. Abstract
Schwartz PJ, Spazzolini C, Crotti L, Bathen J, Amlie JP, Timothy K, Shkolnikova M, Berul CI, Bitner-Glindzicz M, Toivonen L, Horie M, Schulze-Bahr E, Denjoy I. The Jervell and Lange-Nielsen syndrome: natural history, molecular basis, and clinical outcome. Circulation 2006;113: 783-790. Abstract
Stegger L, Hoffmeier A-N, Schäfers KP, Hermann S, Schober O, Schäfers MA, Theilmeier G. Accurate noninvasive measurement of infarct size in mice with high-resolution PET. J Nucl Med 2006;47: 1837-1844. Abstract
Stypmann J, Janssen PML, Prestle J, Engelen MA, Kogler H, Lullmann-Rauch R, Eckardt L, von Figura K, Landgrebe J, Mleczko A, Saftig P. LAMP-2 deficient mice show depressed cardiac contractile function without significant changes in calcium handling. Basic Res Cardiol 2006;101: 281-291. Abstract
Theilmeier G, Schmidt C, Herrmann J, Keul P, Schäfers M, Herrgott I, Mersmann J, Larmann J, Hermann S, Stypmann J, Schober O, Hildebrand R, Schulz R, Heusch G, Haude M, von Wnuck Lipinski K, Herzog C, Schmitz M, Erbel R, Chun J, Levkau B. High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor. Circulation 2006;114: 1403-1409. Abstract
Wagner S, Breyholz H-J, Faust A, Holtke C, Levkau B, Schober O, Schafers M, Kopka K. Molecular imaging of matrix metalloproteinases in vivo using small molecule inhibitors for SPECT and PET. Curr Med Chem 2006;13: 2819-2838. Abstract
Wagner S, Dybkova N, Rasenack ECL, Jacobshagen C, Fabritz L, Kirchhof P, Maier SKG, Zhang T, Hasenfuss G, Brown JH, Bers DM, Maier LS. Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels. J Clin Invest 2006;116: 3127-3138. Abstract
Wagner S, Law MP, Riemann B, Pike VW, Breyholz H-J, Höltke C, Faust A, Renner C, Schober O, Schäfers M, Kopka K. Synthesis of an 18F-labelled high affinity β1-adrenoceptor PET radioligand based on ICI 89,406. J Label Compd Radiopharm 2006;49: 177-195. Abstract


Ropinski T, Steinicke F, Hinrichs K. Interactive Importance-Driven Visualization Techniques for Medical Volume Data. VMV 2005: 273-280.
Schulze-Bahr E, Kirchhof P, Eckardt L, Bertrand J, Breithardt G. Gender differences in cardiac arrhythmias. Herz 2005;30: 390-400. Abstract
Wagner S, Law MP, Riemann B, Pike VW, Breyholz H-J, Höltke C, Faust A, Schober O, Schäfers M, Kopka K. Synthesis of (R)- and (S)-[O-methyl-11C]N-[2-[3-(2-cyano-phenoxy)-2-hydroxy-propylamino]-ethyl]-N′-(4-methoxy-phenyl)-urea as candidate high affinity β1-adrenoceptor PET radioligands. J Label Compd Radiopharm 2005;48: 721-733. Abstract

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