Fachbereich 12 - Chemie und Pharmazie
Organisch-Chemisches Institut
Professor Dr. Werner Klaffke

Research topics

Research Topics: Carbohydrate Chemistry, Analysis of glycosides in tissue and hair, Prediction and Characterisation of Maillard processes, Mathematical modelling of complex chemical networks; Screening and Pharmacophore Modeling.

Drittmittelgeber:

Bundesministerium für Verbraucherschutz, Ernährung und Landwirtschaft, Deutsche Forschungsgemeinschaft, Unilever plc, Graduiertenkolleg "Template Oriented Synthesis", Verband der Chemischen Industrie, Alexander von Humboldt-Stiftung.

Veröffentlichungen:

M. Whittle, P. Willett, W. Klaffke, P. van Noort, Evaluation of Similarity Measures for Searching the Dictionary of Natural Products Database, J. Chem. Inf. Sci., 2003 article asap

C. Ernst, M. Piacenza, S. Grimme, W. Klaffke, Epoxidation of C-branched glycals: unexpected stereochemical results and their theoretical explanation, Carbohydrate Res. 338 (2003) 231-236.

P.W. Braat, W. Klaffke, J.T.W.M. Tissen, A. Visser, Process and equipment for preparing flavouring compositions, Publication Date : 07.08.2002; Publication No: EP 1 228 704 A1

S. Russell, S. Patel, J. Rabone, J. Tissen, W. Klaffke, Iterated Reaction Graphs: Computer Simulation of the Maillard Volatile Compounds, International Congress Series, 1245 (2002) 235-238.

K. Küpker, M. Pearce, W. Klaffke, Amadori Reaction in Hair Compositions, Case No. J 3654, date of filing: 28.03.2002.

T. Schmelter, R. Wientjes, R. Vreeker, W. Klaffke, Enzymatic modifications of Pectins and the Impact on their rheological Properties , Carbohydrate Polymers, 47 (2002) 99-108.

W. Klaffke, Geur op Bestelling, Natuur & Techniek 70 (2002) 50-54. S. Patel, S. Russell, J. Tissen, W. Klaffke, Process for Preparing Flavour Compounds, EP 00 30 6249; WO02/07540.

S. Patel, S. Russell, J. Tissen, W. Klaffke, Method for simulating chemical reactions, WO 02/08839; EP 00 30 6250.

W. Klaffke, Maillard-Chemie: Aroma's op Bestelling, Chemisch 2 Weekblad, 24 (2001) 14-15.

C. Ernst, W. Klaffke, A short route to nucleoside diphosphate activated D- and L-hexoses, Tetrahedron Lett., 42, (2001), 2973-2975.

A. Visser, P. Braat, J. Tissen, W. Klaffke, Process for preparing flavouring compositions, EP01200379.

D. Ramos, W. Klaffke, Chemo-enzymatic Synthesis of Neoglycopeptides: Application to an a-Gal Terminated Neoglycopeptide, J. Org. Chem., 66 (2001) 2948-2956.

S. Patel, J. Rabone, S. Russell, J. Tissen, W. Klaffke, Iterated Reaction Graphs: Simulating Complex Maillard Reaction Pathways, J. Chem. Inform Comp. Science, 41 (2001) 926-933.

T. Schmelter, R. Vreeker, W. Klaffke, Characterisation of a Novel Gel System Containing Pectin, Heat Inactivated Pectin Methylesterase and NaCl, Carbohydrate Polymers, 45, (2001), 277-284.

DISSERTATIONS:

Kerstin Küpker, Investigation of human hair carbohydrates and development of a new active (2002)

Stefan Natsch, Kinetische Untersuchung der Phosphorylierung synthetischer Desxy- und C-verzweigter Zucker mit Hexokinase aus Hefe