Fachbereich 12 - Chemie und Pharmazie
Organisch-Chemisches Institut
Dr. Richard Göttlich

New reagents for organic synthesis and catalysis

New reagents For organic synthesis and catalysis: The reactivity of nitrogen-heteroatom bonds; new oxidation-reactions; formation of carbon-nitrogen bonds; transition-metal catalysis; radical-reactions; heterocycles; natural product synthesis; ligand-design; conformational design; molecular switches.

Drittmittelgeber:

Fonds der Chemischen Industrie, Alfried Krupp von Bohlen und Halbach-Stiftung, DFG, SFB 424.

Veröffentlichungen:

R. W. Hoffmann, R. Göttlich, U. Schopfer: Conformation Induction Between Neighboring Dimethylpentane Segments. Eur. J. Org. Chem. 2001, 1865-1871

R. Göttlich, M. Noack: Samarium(II)-iodide Catalyzed Addition of N-Chloramines to Double Bonds, a Iodide-catalyzed reaction. Tetrahedron Lett. 2001, 7771

M. Noack, R. Göttlich: Copper(I) catalysed cyclisation of unsaturated N-benzoyloxyamines: an aminohydroxylation via radicals. Chem. Commun. 2002, 536

J. Helaja, R. Göttlich: A new catalytic hetero-Heck type reaction Chem. Commun. 2002, 720

G. Heuger, S. Kalsow, R. Göttlich: Copper(I)-catalysts for the stereoselective addition of N-chloroamines to double bonds, a diastereoselective radical cyclisation. Eur. J. Org. Chem. 2002, 1848.

M. Noack, R. Göttlich: Cyclisation of N-chloroamines catalysed by iodide, a new way to synthesise 3-chloropiperidines. Eur. J. Org. Chem. 2002, 3171.

I. Schulte-Wülwer, J. Helaja, R. Göttlich: Copper(I)-catalysed cyclisation of unsaturated N-chloroamides. Synthesis, accepted for publication.

M. Noack, R. Göttlich: Lewis-acids for the cyclisation of unsaturated chloroamines, evidence for a polar reaction. Submitted for publication.

Diane Bülters, Richard Göttlich: N-Chloroamines as Oxidants: A Swern-type Oxidation at room-temperature without addition of excess base. Submitted for publication

S. Kalsow, B. M. Brand, R. Göttlich: Stereselective synthesis of both enantiomers of epi-deoxynojirimycine and deoxynojirimycine. In preparation

G. Heuger, A. Blömker, R. Göttlich: Iron(II)-catalysed cyclisation of unsaturated chloroamines. In preparation

Markus Zander, Peter Knoop, Michael Noack, Richard Göttlich: N-Chloramines and acids, a new efficient source of haloniumions. In preparation

DISSERTATIONS:

Michael Noack: “Katalytische Oxidation von Doppelbindungen mit N-Heteroatom substituierten Aminen: Synthese funktionalisierter Piperidine und Pyrrolidine“