Westfälische Wilhelms-Universität Münster
Forschungsbericht 2001-2002
 
Klinik und Poliklinik für
Allgemeine Orthopädie

Albert-Schweitzer-Str. 33
48143 Münster
Direktor: Prof. Dr. Med. Winfried Winkelmann
 
Tel. (0251) 83-47902/03
Fax: (0251) 83-47989
e-mail: winkelma@uni-muenster.de
www: http://www.klinikum.uni-muenster.de/institute/orth/
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[Pfeile  braun]

Forschungsschwerpunkte 2001 - 2002

Fachbereich 05 - Medizinische Fakultät
Klinik und Poliklinik für Allgemeine Orthopädie
Knochentumoren


Korrelation von objektiven Parametern (Gangbild, Fitness) zu subjektivem Lebensgefühl
(Lebensqualität, Lebenszufriedenheit, Rehabilitation) bei Tumorpatienten nach
extremitätenerhaltender Tumorresektion im Bereich des Kniegelenkes

Beteiligte Wissenschaftler:

Dr. R. Rödl, Dr. E. Eils, PD Dr. D. Rosenbaum

Veröffentlichungen:

Decker S, van Valen F, Vischer P. Adhesion of osteosarcoma cells to the 70-kDa core region of thrombospondin-1 is mediated by the alpha 4 beta 1 integrin. Biochem Biophys Res Commun 293, 86-92, 2002

Franzius C, Kopka K, van Valen F, Eckervogt V, Riemann B, Sciuk J, Schober O. Characterization of 3-[123I]iodo-L-a-methyl tyrosine ([123I]IMT) transport into human Ewing's sarcoma cells in vitro. Nucl Med Biol 28, 123–128, 2001

Franzius C, Kopka K, van Valen F, Riemann B, Sciuk J, Schober O. 3-[123I]Iodo-L-a -methyl tyrosine transport into human fibroblasts and comparison with Ewing's sarcoma cells Nucl Med Biol 29, 483–490, 2002Decker S, van Valen F, Vischer P. Adhesion of osteosarcoma cells to the 70-kDa core region of thrombospondin-1 is mediated by the alpha 4 beta 1 integrin. Biochem Biophys Res Commun 293, 86-92, 2002

Franzius C, Kopka K, van Valen F, Eckervogt V, Riemann B, Sciuk J, Schober O. Characterization of 3-[123I]iodo-L-a-methyl tyrosine ([123I]IMT) transport into human Ewing's sarcoma cells in vitro. Nucl Med Biol 28, 123–128, 2001

Franzius C, Kopka K, van Valen F, Riemann B, Sciuk J, Schober O. 3-[123I]Iodo-L-a -methyl tyrosine transport into human fibroblasts and comparison with Ewing's sarcoma cells Nucl Med Biol 29, 483–490, 2002

Fulda S, Küfer MU, Meyer E, van Valen F, Dockhorn-Dworniczak B, Debatin KM. Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer Oncogene 20, 5865-5877, 2001

Schäfer KL, Wai DH, Poremba C, Korsching E, van Valen F, Ozaki T, Boecker W, Dockhorn-Dworniczak B. Characterization of the malignant melanoma of soft-parts cell line GG-62 by expression analysis using DNA microarrays. Virchows Arch 440, 476-484, 2002

Scheel C, Schäfer KL, Jauch A, Keller M, Wai D, Brinkschmidt C, van Valen F, Böcker W, Dockhorn-Dworniczak B, Poremba C. Alternative lengthening of telomeres is associated with chromosomal instability in osteosarcomas. Oncogene 20, 3835-3844, 2001

Sonnemann J, Eckervogt V, Truckenbrod B, Boos J, Winkelmann W, van Valen F. The bisphosphonate pamidronate is a potent inhibitor of human osteosarcoma cell growth in vitro. Anticancer Drugs 12, 459-465, 2001

Vormoor J, Baersch G, Decker S, Hotfilder M, Schäfer KL, Pelken L, Rübe C, van Valen F, Jürgens H, Dockjhorn-Dworniczak B. Establishment of an in vivo model for pediatric Ewing tumors by transplantation into NOD/scid Mice. Ped Res 49, 332-341, 2001

Wai DH, Schäfer KL, Schramm A, Korsching E, van Valen F, Ozaki T, Böcker W, Schweigerer L, Dockhorn-Dworniczak B, Poremba C. Expression analysis of pediatric solid tumor cell lines using oligonucleotide microarrays. Int J Oncol 20, 441-451, 2002

Fulda S, Küfer MU, Meyer E, van Valen F, Dockhorn-Dworniczak B, Debatin KM. Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer Oncogene 20, 5865-5877, 2001

Schäfer KL, Wai DH, Poremba C, Korsching E, van Valen F, Ozaki T, Boecker W, Dockhorn-Dworniczak B. Characterization of the malignant melanoma of soft-parts cell line GG-62 by expression analysis using DNA microarrays. Virchows Arch 440, 476-484, 2002

Scheel C, Schäfer KL, Jauch A, Keller M, Wai D, Brinkschmidt C, van Valen F, Böcker W, Dockhorn-Dworniczak B, Poremba C. Alternative lengthening of telomeres is associated with chromosomal instability in osteosarcomas. Oncogene 20, 3835-3844, 2001

Sonnemann J, Eckervogt V, Truckenbrod B, Boos J, Winkelmann W, van Valen F. The bisphosphonate pamidronate is a potent inhibitor of human osteosarcoma cell growth in vitro. Anticancer Drugs 12, 459-465, 2001

Vormoor J, Baersch G, Decker S, Hotfilder M, Schäfer KL, Pelken L, Rübe C, van Valen F, Jürgens H, Dockjhorn-Dworniczak B. Establishment of an in vivo model for pediatric Ewing tumors by transplantation into NOD/scid Mice. Ped Res 49, 332-341, 2001

Wai DH, Schäfer KL, Schramm A, Korsching E, van Valen F, Ozaki T, Böcker W, Schweigerer L, Dockhorn-Dworniczak B, Poremba C. Expression analysis of pediatric solid tumor cell lines using oligonucleotide microarrays. Int J Oncol 20, 441-451, 2002

Rödl R., U. Pohlmann, G. Gosheger, Ch. Hoffmann, B. Leidinger, N. Lindner, W. Winkelmann: Ablative und extremitätenerhaltende Tumorchirurgie der unteren Extremität – Ein Zehnjahresvergleich. Z Orthop 139, 183-8, 2001

Hillmann, A., D. Rosenbaum, G. Gosheger, Ch. Hoffmann, R. Rödl, W. Winkelmann: Rotationplasty Type B IIIa according to Winkelmann - Electromyography and gait analysis. Clin Orthop. 384, 224-231, 2001

 
 

Hans-Joachim Peter
EMail: vdv12@uni-muenster.de
HTML-Einrichtung: Izabela Klak
Informationskennung: FO05BAA08
Datum: 2004-04-29