Westfälische Wilhelms-Universität Münster
Forschungsbericht 2001-2002
 
Klinik und Poliklinik für Hautkrankheiten
- Allgemeine Dermatologie und Venerologie -

Von-Esmarch-Str. 58
48149 Münster
Leiter: Prof. Dr. Thomas Luger
 
Tel. (0251) 83-5 6504
Fax: (0251) 83-5 6522
e-mail: derma@uni-muenster.de
www: http://www.klinikum.uni-muenster.de/institute/derma/
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[Pfeile  braun]

Forschungsschwerpunkte 2001 - 2002

Fachbereich 05 - Medizinische Fakultät
Klinik und Poliklinik für Hautkrankheiten - Allgemeine Dermatologie und Venerologie -
Publikationen 2002


Originalarbeiten

Veröffentlichungen:

Ackerman AB, Metze D, Kutzner H. Erythematous papules and nodules after tick bite. Am J Dermatopathology, 24:427-428 (2002)

Assmann K, Nashan D, Grabbe S, Luger TA, Metze D. Persistierende knotige Lokalreaktion mit Lymphom-ähnlichen Infiltrationen nach s.c.-Injektion von Interleukin-2. Hautarzt 53: 554-557 (2002)

Bauer J, Schumann H, Sonnichsen K, Tomaske M, Bosk A, Bruckner-Tuderman L, Rassner G, Garbe C. Molecular diagnostics facilitate distinction between lethal and non-lethal subtypes of junctional epidermolysis bullosa: a case report and review of the literature. Eur J Pediatr 161: 672-679 (2002)

Binder B, Metze D, Smolle J. Kongenitale bullöse Poikilodermie (Kindler Syndrom). Hautarzt, 53: 546-549 (2002)

Böhm M, Schiller M, Ständer S, Seltmann H, Li Z, Brzoska T, Metze D, Schiöth H, Skottner A, Seiffert K, Zouboulis C, Luger TA. Evidence for expression of melanocortin-1 receptor in human sebocytes in vitro and in situ. J Invest Dermatol 118: 533-539 (2002)

Böhm M, Schmidt PF, Lödding B, Uphoff H, Westermann G, Luger TA, Bonsmann G, Metze D. Cutaneous hyperpigmentation induced by doxycycline. Am J Dermatopathol 24 (4): 345-350 (2002)

Böhm M, Luger TA, Traupe H: Successful treatment of inflammatory linear verrucous epidermal nevus (ILVEN) with topical natural vitamin D3 (clacitriol). Brit J Dermatol (2002) (in press)

Böhm M, Frieling U, Luger TA, Bonsmann G. Successful treatment of anogenital lichen sclerosis with topical tacrolimus. Arch Dermatol (2002) (in press)

Brehler R, Kütting B, Rütter A, Luger TA. Positive effects of a fresh air filtration system on hay fever symptoms. J Clin Exp Allergy (2002) (in press)

Brehler R, Rütter A, Kütting B. Allergenicity of natural rubber latex gloves. Contact Dermatitis 46: 65-71 (2002)

Eckl KM, Stevens HP, Lestringant GG, Westenberger-Treumann M, Traupe H, Hinz B, Frossard PM, Stadler R, Leigh IM, Nurnber PA, Hennies HC. Mal de Meleda (MDM) caused by mutations in the gene for SLURP-1 in patients from Germany, Turkey, Palestine and the United Arabic Emirates. Hum Genet (2002) (in press)

Franzke CW, Tasanen K, Schäcke H, Zhou Z, Tryggvason K, Mauch C, Zigrino P, Sunnarborg S, Lee DC, Fahrenholz F, Bruckner-Tuderman L. Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs. EMBO J 21: 5026-5035 (2002)

Gerbing EK, Metze D, Luger TA, Ständer S: Interstitielle granulomatöse Dermatitis ohne Arthritis. Erfolgreiche Therapie mit Hydroxychloroquin. JDDG (2002) (in press)

Grabbe S, Pendl G, Steinert M, Beissert S, Varga G, Sunderkötter C, Peters T, Schwarz T, Scharffetter-Kochanek K. Beta2 integrins are required for skin homing of primed T cells but not for priming naïve T cells. J Clin Invest 109:183-192 (2002)

Grabbe S, Gansz B, Loske KD, Nashan D. Adjuvante Therapie der high-risk Melanoms: Erste klinische Erfahrungen mit pegyliertem Interferon. Dt. Dermatol. Suppl. 68, 3-4 (2002)

Has C, Seedorf U, Kannenberg F, Bruckner-Tuderman L, Folkers E, Fölster-Holst R, Baric I, Traupe H. Gas chromatography-mass Spectrometry and molecular genetic studies in families with the Conradi-Hünermann-Happle syndrome. J Invest Dermatol 118:851-858 (2002)

Hensen P, Windemuth C, Rüschendorf F, Stadelmann A, Nürnberg G, Hoppe V, Fenneker D, Ständer M, Schmitt-Egenolf M, Wienker TF, Traupe H, Reis A. Linkage disequilibrium mapping in the Novel psoriasis susceptibility region on chromosome 19: evidence for both susceptible and protective loci. Exp Dermatol (2002) (in press)

Hensen P, Asadullah K, Windemuth C, Rüschendorf F, Hüffmeier U, Ständer M, Schmitt-Egenolf M, Wienker T F, Reis A, Traupe H. Interleukin-10 promoter polymorphism IL10.G and familial early onset psoriasis . Brit J Dermatol (2002) (in press)

Hoffmeier A, Wagner T, Nashan D, Rukosujew A, Erren M, Schmid C, Wirtz Sp, Scheld HH . Tumorerkrankungen nach Herztransplantation. Zeitschr. für Kardiologie 91: 1013-1023 (2002)

Huber M, Floeth M, Borradori M, Schäcke H, Hohl D, Bruckner-Tuderman L. A large in frame deletion in the cytoplasmatic domain of BP180/collagen XVII causes a phenotype with features of both simplex and junctional epidermolysis bullosa. J Invest Dermatol 118, 185-192 (2002)

Kuhn A, Brachtendorf G, Kurth F, Sonntag M, Samulowitz U, Metze D, Vestweber D. Expression of endomucin, a novel endothelial sialomucin in normal and diseased human skin. J Invest Dermatol, 119:1388-1393 (2002)

Kulms D, Düßmann H,Pöppelmann B, Ständer S, Schwarz A, Schwarz T. Apoptosis induced by disruption of the actin cytoskeleton is mediated via activation of CD95 (Fas/APO-1). Cell Death Differ 9: 598-608 (2002)

Kulms D, Zeise E, Pöppelmann B, Schwarz T. DNA damage, death receptor activation and reactive oxygen species contribute to ultraviolet radiation-induced apoptosis in an essential and independent way. Oncogene 21: 5844 - 5851 (2002)

Mecklenbeck S, Compton S, Cervini R, Meija J, Hovnanian A, Bruckner-Tuderman L, Barrandon Y. Microinjection of the COL7A1 gene into collagen VII-deficient epidermolysis bullosa keratinocytes leads to synthesis and secretion of normal procollagen VII. Hum Gene Ther 13: 1655-1662 (2002)

Metze D. Drug eruptions: Clinico-pathologic correlation in the same lesion. Dermatopathology: Practical and conceptual, 8 (2002)

Metze D. Drug eruptions: Exanthematous, Macular, and Papular Type. Dermatopathology: Practical and conceptual, 8 (2002)

Nakano A, Sheau-Chiou C, Pulkkinen L, Murrell D, Bruckner-Tuderman L, Pfendner E, Uitto J. Laminin 5 mutations in junctional epidermolysis bullosa: molecular basis of Herlitz vs. non-Herlitz phenotypes. Human Genet. 110, 41-51 (2002)

Nashan D, Hoffmeier A, Frieling U, Dehning S, Ständer S, Luger TA, Scheld HH. Hauttumoren, assoziiert mit kumulativer Immunsuppression: Dermatologische Screening-Untersuchung von 119 herztransplantierten Patienten. Z Herz- Thorax- Gefäßchir 16 (Suppl 1): I/72-I/80 (2002)

Nashan D, Kocer B, Schiller M, Luger T, Grabbe S: Significant risk of a second melanoma in patients with a history of melanoma but no further predisposing factors. Dermatology (2002) (in press)

Pendl G, Robert C, Fuhlbrigge R, Thanos R, Eytner E, Borges E, Steinert M, Kupper TS, Vestweber D, Grabbe S. The P-selectin glycoprotein ligand-1 of immature mouse dendritic cells binds to P- and E-selectin, but is not required for transmigration into inflamed tissue. Blood 99: 946-956 (2002)

Planelles L, Thomas M, Pulgar M, Grabbe S, Sanchez-Madrid S. Trypanosoma cruzi heat-shock protein-70 kDa, alone or fused to the parasite KMP11 antigen, induces functional maturation of murine dendritic cells. Immunol Cell Biol 80: 241-247 (2002)

Schmidt E, Höpfner B, Chen M, Weber L, Bröcker E-B, Bruckner-Tuderman L, Zillikens D. Childhood epidermolysis bullosa acquisita: a novel variant with reactivity with all three structural domains of collagen VII. Br J Dermatol 147, 592 - 597 (2002)

Rattenholl A, Pappano W, Koch M, Keene DR, Kadler K, Sasaki T, Timpl R, Burgeson RE, Greenspan D and Bruckner-Tuderman L. Proteinases of the BMP-1 family convert procollagen VII to mature anchoring fibril collagen. J Biol Chem 277: 26372-26378 (2002)

Schäppi H, Emberger M, Wieland U, Metze D, Bauer JW, Pohla-Gubo G, Thaller-Antlanger H, Hintner H. Unilateral Blepharochalasis mit läsionalen IgA-Ablagerungen. Hautarzt 53: 613-617 (2002)

Scholzen T, Sunderkötter C, Kalden H, Brzoska T, Fastrich M, Fisbeck T, Armstrong CA, Ansel JC, Luger TA. Alpha-melanocyte stimulating hormone prevents lipopolisaccharide-induced vasculitis by downregulating endothelial cell adhesion molecule expression. Endocrinology (2002) (in press)

Schwarz A, Ständer S, Berneburg M, Böhm M, Kulms D, Van Steeg H, Große-Heitmeyer K, Krutmann J and Schwarz T. Interleukin-12 suppresses ultaviolet radiation-induced apoptosis by inducing DNA repair. Nature Cell Biol 4: 26-31 (2002)

Shpacovitch V, Brzoska T, Buddenkotte J, Stroh C, Sommerhoff C, Ansel JC, Schulze-Osthoff K, Bunnett N, Luger TA, Steinhoff M. Agonists of proteinase-activated receptor-2 induce cytokine release and activation of nuclear transcription factor kB in human dermal microvascular endothelial cells. J Invest Dermatol 118: 380-385 (2002)

Ständer H, Ständer S, Luger TA, Schwarz T. Topisches Interferon-b. Ein Vorschlag zur additiven Therapie der ulzerierten Mycosis fungoides. Hautarzt 52: 882-884 (2002)

Ständer, H., M. Schiller, T. Schwarz. UVA1-therapy for treatment of sclerodermic graft-versus-host-disease of the skin. (Letter to the Editor). J Am Acad Dermatol. 46: 799-800 (2002)

Ständer S, Böhm M, Brzoska T, Zimmer KP, Luger TA, Metze D. Expression of melanocortin-1 receptor in normal, malformed and neoplastic skin glands and hair follicles. Exp Dermatol 11 (1): 42-51 (2002)

Ständer S, Gunzer M, Metze D, Luger TA, Steinhoff M. Localization of µ-opioid receptor 1A on sensory nerve fibers in human skin. Regulatory Peptides 110: 75-83 (2002)

Ständer S, Gunzer M, Metze D, Luger TA, Steinhoff M. Localization of µ-opioid receptor 1A (MOR 1A) on sensory nerve finbers in human skin. Regulatory Peptides (2002) (in press)

Ständer S, Bone HG, Machens HG, Aberle T, Burchard W, Prien T, Luger TA, Metze D. Hydroxyethyl starch (HES) does not cross the blood-brain or the placental barrier but the perineurium of peripheral nerves in infused animals. Cell and Tissue Research 301: 279-278 (2002)

Steinhoff M, Emmert S, Rünger TM. Serpiginös-ulcero-tuberöses Syphilid bei Lues III. Ein Fallbericht. Hautarzt (2002) (in press)

Vergnolle N, Derian C, D'Andrea M, Steinhoff M, Andrade-Gordon P. Characterization of thrombin-induced leukocyte rolling and adherence: a potential pro-inflammatory role for Proteinase-Activated Receptor-4 (PAR-4). J Immunol 167: 2239-2247 (2002)

Willems M, Munte K, Vrolijk JM, den Hollander JC, Böhm M, Kemmeren MH, de Man RA, Brouwer HT. Hyperpigmentation during interferon-alpha therapy for chronic hepatitis C virus infection. Br. J. Dermatol (2002) (in press)

Zimmer P, Schumann H, Mecklenbeck S, Bruckner-Tuderman L. Dysphagia and esophageal stenosis: an extracutaneous form of dystrophic epidermolysis bullosa due to mutations in the collagen VII gene. Gastroenterology 122, 220-225 (2002)

 
 

Hans-Joachim Peter
EMail: vdv12@uni-muenster.de
HTML-Einrichtung: Izabela Klak
Informationskennung: FO05AEG01
Datum: 2003-09-26