Publications

List of INMiND related peer-reviewed papers


2017

Adamczak J, Aswendt M, Kreutzer C, Rotheneichner P, Riou A, Selt M, Beyrau A, Uhlenküken U, Diedenhofen M, Nelles M, Aigner L, Couillard-Despres S, Hoehn M. Neurogenesis upregulation on the healthy hemisphere after stroke enhances compensation for age-dependent decrease of basal neurogenesis. Neurobiol Dis. 2017;99:47-57.
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Ahamed M, Attili B, van Veghela D, Ooms M, Berben P, Celen S, Koole M, Declercq L, Savinainen J, Laitinen J, Verbruggen A, Bormans G. Synthesis and preclinical evaluation of [11C]MA-PB-1 for in vivo imaging of brain monoacylglycerol lipase (MAGL). Eur J Med Chem. 2017;136:104-113.
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Airas L, Rissanen E, Rinne J. Imaging of microglial activation in MS using PET: Research use and potential future clinical application. Mult Scler. 2017;23(4):496-504.
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Beaino W, Janssen B, Kooij G, van der Pol SMA, van Het Hof B, van Horssen J, Windhorst AD, de Vries HE. Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis. J Neuroinflammation. 2017;14(1):259.
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Beliveau V, Ganz M, Feng L, Ozenne B, Højgaard L, Fisher PM, Svarer C, Greve DN, Knudsen GM. A high-resolution in vivo atlas of the human brain's serotonin system. J Neurosci. 2017;37(1):120-128.
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Belloli S, Pannese M, Buonsanti C, Maiorino C, Di Grigoli G, Carpinelli A, Monterisi C, Moresco RM, Panina-Bordignon P. Early upregulation of 18-kDa translocator protein in response to acute neurodegenerative damage in TREM2-deficient mice. Neurobiol Aging. 2017;53:159-168.
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Benedusi V, Della Torre S, Mitro N, Caruso D, Oberto A, Tronel C, Meda C, Maggi A. Liver ERα regulates AgRP neuronal activity in the arcuate nucleus of female mice. Sci Rep. 2017;7(1):1194.
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Bertoglio D, Verhaeghe J, Santermans E, Amhaoul H, Jonckers E, Wyffels L, Van Der Linden A, Hens N, Staelens S, Dedeurwaerdere S. Non-invasive PET imaging of brain inflammation at disease onset predicts spontaneous recurrent seizures and reflects comorbidities. Brain Behav Immun. 2017;61:69-79.
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Bonfill-Teixidor E, Otxoa-de-Amezaga A, Font-Nieves M, Sans-Fons MG, Planas AM. Differential expression of E-type prostanoid receptors 2 and 4 in microglia stimulated with lipopolysaccharide. J Neuroinflammation. 2017;14(1):3.
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Bozó T, Wacha A, Mihály J, Bóta A, Kellermayer MS. Dispersion and stabilization of cochleate nanoparticles. Eur J Pharm Biopharm. 2017;117:270-275.
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Brufani M, Rizzi N, Meda C, Filocamo L, Ceccacci F, D’Aiuto V, Bartoli G, La Bella A, Migneco LM, Marini Bettolo R, Leonelli F, Ciana P, Maggi A. Novel Locally Active Estrogens Accelerate Cutaneous Wound Healing-Part 2. Sci Rep. 2017;7(1):2510.
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Cacheux F, Médran-Navarrete V, Dollé F, Marguet F, Puech F, Damont A. Synthesis and in vitro characterization of novel fluorinated derivatives of the translocator protein 18 kDa ligand CfO-DPA-714. Eur J Med Chem. 2017;125:346-359.
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Caillé F, Cacheux F, Peyronneau MA, Jego B, Jaumain E, Pottier G, Ullmer C, Grether U, Winkeler A, Dollé F,  Damont A, Kuhnast B. From structure-activity relationships on thiazole derivatives to the in vivo evaluation of a new radiotracer for cannabinoid subtype 2 PET imaging. Mol Pharm. 2017;14(11):4064-4078.
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Caminiti SP, Presotto L, Baroncini D, Garibotto V, Moresco RM, Gianolli L, Volonté MA, Antonini A, Perani D. Axonal damage and loss of connectivity in nigrostriatal and mesolimbic dopamine pathways in early Parkinson's disease. Neuroimage Clin. 2017;14:734-740.
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Caminiti SP, Tettamanti M, Sala A, Presotto L, Iannaccone S, Cappa SF, Magnani G and Perani D; Alzheimer’s Disease Neuroimaging Initiative (ADNI). Metabolic connectomics targeting brain pathology in dementia with Lewy bodies. J Cereb Blood Flow Metab. 2017;37(4):1311-1325.
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Cerami C, Iaccarino L, Perani D. Molecular imaging of neuroinflammation in neurodegenerative dementias: The role of in vivo PET imaging. Int J Mol Sci. 2017;18(5).
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Collste K, Plavén-Sigray P, Fatouros-Bergman H, Victorsson P, Schain M, Forsberg A, Amini N, Aeinehband S; Karolinska Schizophrenia Project (KaSP) consortium., Erhardt S, Halldin C, Flyckt L, Farde L, Cervenka S. Lower levels of the glial cell marker TSPO in drug-naïve first episode psychosis patients as measured using PET and [11C]PBR28. Mol Psychiatry. 2017;22(6):850-856.
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De La Fuente AG, Lange S, Silva ME, Gonzalez GA, Tempfer H, van Wijngaarden P, Zhao C, Di Canio L, Trost A, Bieler L, Zaunmair P, Rotheneichner P, O'Sullivan A, Couillard-Despres S, Errea O, Mäe MA, Andrae J, He L, Keller A, Bátiz LF, Betsholtz C, Aigner L, Franklin RJM, Rivera FJ. Pericytes stimulate oligodendrocyte progenitor celldifferentiation during CNS remyelination. Cell Rep. 2017;20(8):1755-1764.
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Della Torre S, Maggi A. Sex Differences: A Resultant of an Evolutionary Pressure? Cell Metabolism 2017; 25(3):499–505.
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Dupont AC, Largeau B, Santiago Ribeiro MJ, Guilloteau D, Tronel C, Arlicot N. Translocator protein-18kDa (TSPO) positron emision tomography (PET) imaging and it clinical impact in neurodegenerative diseases. Int J Mol Sci. 2017;18(4):785.
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Feng L, Jensen P, Thomsen G, Dyssegaard A, Svarer C, Knudsen LV, Møller K, Thomsen C, Mikkelsen JD, Guilloteau D, Knudsen GM, Pinborg LH. The Variability of Translocator Protein Signal in Brain and Blood of Genotyped Healthy Humans using in vivo [123I]CLINDE-SPECT imaging – a test-retest study.  J Nucl Med. 2017;58(6):989-995.
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Filippi M, Catanzaro V, Patrucco D, Botta M, Tei L, Terreno E. First in vivo MRI study on theranostic dendrimersomes. J Control Release. 2017; 248: 45-52.
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Forsberg A, Cervenka S, Jonsson Fagerlund M, Rasmussen LS, Zetterberg H, Erlandsson Harris H, Stridh P, Christensson E, Granström A, Schening A, Dymmel K, Knave N, Terrando N, Maze M, Borg J, Varrone A, Halldin C, Blennow K, Farde L, Eriksson LI. The immune response of the human brain to abdominal surgery. Ann Neurol. 2017;81(4):572-582.
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Foucault-Fruchard L, Doméné A, Page G, Windsor M, Emond P, Rodrigues N, Dollé F, Damont A, Buron F, Routier S, Chalon S, Antier D. Neuroprotective effect of the alpha 7 nicotinic receptor agonist PHA 543613 in an in vivo excitotoxic adult rat model. Neuroscience. 2017;356:52-63.
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Fricke IB, Schelhaas S, Zinnhardt B, Viel T, Hermann S, Couillard-Després S, Jacobs AH. In vivo bioluminescence imaging of neurogenesis: the role of the blood brain barrier in an experimental model of Parkinson's disease. Eur J Neurosci. 2017;45(7):975-986.
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Ganz M, Feng L, Hansen HD, Beliveau V, Svarer C, Knudsen GM, Greve DN. Cerebellar heterogeneity and its impact on PET data quantification of 5-HT receptor radioligands. J Cereb Blood Flow Metab. 2017;37(9):3243-3252.
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Gargiulo S, Coda AR, Panico M, Gramanzini M, Moresco RM, Chalon S, Pappatà S. Molecular imaging of neuroinflammation in preclinical rodent models using positron emission tomography. Q J Nucl Med Mol Imaging 2017;61:60-75.
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Golla SS, Timmers T, Ossenkoppele R, Groot C, Verfaillie S, Scheltens P, van der Flier WM, Schwarte L, Mintun MA, Devous M, Schuit RC, Windhorst AD, Lammertsma AA, Boellaard R, van Berckel BN, Yaqub M. Quantification of Tau Load Using [18F]AV1451 PET. Mol Imaging Biol. 2017;19(6):963-971.
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Golla SSV, Lubberink M, van Berckel BNM, Lammertsma AA, Boellaard R. Partial volume correction of brain PET studies using iterative deconvolution in combination with HYPR denois. EJNMMI Res. 2017;7(1):36.
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Hugenberg V, Wagner S, Kopka K, Schäfers M, Schuit RC, Windhorst AD, Hermann S. Radiolabeled Selective Matrix Metalloproteinase 13 (MMP-13) Inhibitors: (Radio)Syntheses and in Vitro and First in Vivo Evaluation. J Med Chem. 2017;60(1):307-321.
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Iaccarino L, Chiotis K, Alongi P, Almkvist O, Wall A, Cerami C, Bettinardi V, Gianolli L, Nordberg A, Perani D. A cross-validation of FDG- and amyloid-PET biomarkers inmild cognitive impairment for the risk prediction to dementia due to Alzheimer's Disease in a clinical setting. J Alzheimers Dis. 2017;59(2):603-614.
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Iaccarino L, Presotto L, Bettinardi V, Gianolli L, Roiter I, Capellari S, Parchi P, Cortelli P, Perani D. An in vivo 11C-PK PET study of microglia activation in Fatal Familial Insomnia. Ann Clin Transl Neurol. 2017;5(1):11-18.19(5):736-745.
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Keller T, Krzyczmonik A, Forsback S, López Picón FR, Kirjavainen AK, Takkinen J, Rajander J, Cacheux F, Damont A, Dollé F, Rinne JO, Haaparanta-Solin M, Solin O. Radiosynthesis and Preclinical Evaluation of [18F]F-DPA, a Novel Pyrazolo[1,5a]pyrimidine Acetamide TSPO Radioligand, in healthy Sprague Dawley rats. Mol Imaging Biol. 2017;19(5):736-745.
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Lauber DT, Fülöp A, Kovács T, Szigeti K, Máthé D, Szijártó A. State of the art in vivo imaging techniques for laboratory animals. Lab Anim. 2017;51(5):465-478.
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Lemoine L, Gillberg P-G, Svedberg M, Stepanov CV, Jia Z, Huang J, Nag S, Tian H, Ghetti B, Okamura N, Higuchi M,  Halldin C, Nordberg A. Comparative binding properties of the tau PET tracers THK5117, THK5351, PBB3, and T807 in postmortem Alzheimer brains. Alzheimers Res Ther. 2017;9(1):96.
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Lemoine L, Saint-Aubert L, Nennesmo I, Gillberg P-G, Nordbrerg A. Cortical laminar tau deposit and activated astrocytes in Alzheimer´s disease visualized by 3H-THK5117 and 3H-deprenyl autoradiography. Sci Rep 2017;7:45496.
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Lepelletier FX, Mann DM, Robinson AC, Pinteaux E, Boutin H. Early changes in extracellular matrix in Alzheimer's disease. Neuropathol Appl Neurobiol. 2017;43(2):167-182.
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Libbrecht S, Van den Haute C, Malinouskaya L, Gijsbers R, Baekelandt V. Evaluation of WGA-Cre-dependent topological transgene expression in the rodent brain. Brain Struct Funct. 2017;222(2):717-733.
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Mártonfalvi Z, Bianco P, Naftz K, Ferenczy GG, Kellermayer M. Force generation by titin folding. Protein Sci. 2017;26(7):1380-1390.
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Nguyen HM, Blomster LV, Christophersen P, Wulff H. Potassium channel expression and function in microglia: Plasticity and possible species variations. Channels (Austin). 2017;11(4):305-315.
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Ni R, Gillberg PG, Bogdanovic N, Viitanen M, Myllykangas L, Nennesmo I, Långström B, Nordberg A. Amyloid tracers binding sites in autosomal dominant and sporadic Alzheimer's disease. Alzheimers Dement. 2017;13(4):419-430.
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O'Brien-Brown J, Jackson A, Reekie TA, Barron ML, Werry EL, Schiavini P, McDonnell M, Munoz L, Wilkinson S, Noll B, Wang S, Kassiou M. Discovery and pharmacological evaluation of a novel series of adamantyl cyanoguanidines as P2X7 receptor antagonists. Eur J Med Chem. 2017;130:433-439.
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Pepe G, Braga D, Renzi TA, Villa A, Bolego C, D’Avila F, Barlassina C, Maggi A, Locati M, Vegeto E. Self-renewal and phenotypic conversion are the main physiological responses of macrophages to the endogenous estrogen surge. Scientific Reports 7: 44270.
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Pepe G, De Maglie M, Minoli L, Villa A, Maggi A, Vegeto E. Selective proliferative response of microglia to alternative polarization signals. J Neuroinflammation. 2017;14(1):236.
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Perani D, Farsad M, Ballarini T, Lubian F, Malpetti M, Fracchetti A, Magnani G, March A, Abutalebi J. The impact of bilingualism on brain reserve and metabolic connectivity in Alzheimer's dementia. Proc Natl Acad Sci U S A. 2017;114(7):1690-1695.
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Pihlaja R, Haaparanta-Solin M, Rinne JO. The anti-inflammatory effects of lipoxygenase and cyclo-oxygenase inhibitors in inflammation-induced human fetal glia cells and the Aβ degradation capacity of human fetal astrocytes in an ex vivo assay. Front Neurosci. 2017;11:299.
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Pires RH, Saraiva MJ, Damas AM, Kellermayer MS. Force spectroscopy reveals the presence of structurally modified dimers in transthyretin amyloid annular oligomers. J Mol Recognit. 2017;30(3).
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Pongor CI, Bianco P, Ferenczy G, Kellermayer R, Kellermayer M. Optical trapping nanometry of hypermethylated CPG-Island DNA. Biophys J. 2017;112(3):512-522.
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Pottier G, Gómez-Vallejo V, Padro D, Boisgard R, Dollé F, Llop J, Winkeler A, Martin A. PET imaging of cannabinoid type 2 receptors with [11C]A-836339 did not evidence changes following. J Cereb Blood Flow Metab. 2017;37(3):1163-1178.
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Presotto L, Ballarini T, Caminiti SP, Bettinardi V, Gianolli L, Perani D. Validation of 18F–FDG-PET Single-Subject Optimized SPM Procedure with Different PET Scanners. Neuroinformatics. 2017;15(2):151-163.
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Rivera FJ, Silva ME, Aigner L. The vascular niche in tissue repair: A therapeutic target for regeneration. Front Cell Dev Biol. 2017;5:88.
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Rizzi N, Rebecchi M, Levandis G, Ciana P, Maggi A. Identification of novel loci for the generation of reporter mice. Nucleic Acids Res 2017;45(6):e37.
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Rodriguez-Vieitez E, Leuzy A, Chiotis K, Saint-Aubert, Wall A, Nordberg A. Comparability of [18F]THK5317 and [11C]PIB blood flow proxy images with [18F]FDG positron emission tomography in Alzheimer's disease. J Cereb Blood Flow Metab. 2017;37(2):740-749.
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Saint-Aubert L, Lemoine L, Chiotis K, Leuzy A, Rodriguez-Vieitez E, Nordberg A. Tau PET imaging: present and future directions. Mol Neurodegener. 2017;12(1):19.
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Sala A, Caminiti SP, Presotto L, Premi E, Pilotto A, Turrone R, Cosseddu M, Alberici A, Paghera B, Borroni B, Padovani A, Perani D. Sci Rep. 2017;7(1):4256.
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Sokias R, Werry EL, Chua SW, Reekie TA, Munoz L, Wong ECN, Itner LM, Kassiou M. Determination and reduction of translocator protein (TSPO) ligand rs6971 discrimination. Med. Chem. Commun. 2017;8:202-210.
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Sridharan S, Lepelletier FX, Trigg W, Banister S, Reekie T, Kassiou M, Gerhard A, Hinz R, Boutin H. Comparative evaluation of three TSPO PET radiotracers in a LPS-induced model of mild neuroinflammation in rats. Mol Imaging Biol. 2017;19(1):77-89.
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Struys T, Govaerts K, Oosterlinck W, Casteels C, Bronckaers A, Koole M, Van Laere K, Herijgers P, Lambrichts I, Himmelreich U, Dresselaers T. In vivo evidence for long-term vascular remodeling resulting from chronic cerebral hypoperfusion in mice. J Cereb Blood Flow Metab 2017; 37(2): 726-739.
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Sucksdorff M, Rissanen E, Tuisku J, Nuutinen S, Paavilainen T, Rokka J, Rinne J, Airas L. Evaluation of the effect of Fingolimod treatment on microglial activation using serial PET imaging in multiple sclerosis. J Nucl Med. 2017;58(10):1646-1651.
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Takkinen JS, López-Picón FR, Al Majidi R, Eskola O, Krzyczmonik A, Keller T, Löyttyniemi E, Solin O, Rinne JO, Haaparanta-Solin M. Brain energy metabolism and neuroinflammation in ageing APP/PS1-21 mice using longitudinal 18F-FDG and 18F-DPA-714 PET imaging.  J Cereb Blood Flow Metab. 2017;37(8):2870-2882.
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Tronel C, Largeau B, Santiago Ribeiro MJ, Guilloteau D, Dupont AC, Arlicot N. Molecular targets for PET imaging of activated microglia: the current situation and future expectations. Int J Mol Sci. 2017;18(4):802.
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Van der Aart J, van der Doef TF, Horstman P, Schuit RC, van Lingen A, Windhorst AD, van Berckel BNM, Lammertsma AA. Human Dosimetry of the NMDA Receptor Ligand [11C]GMOM. J Nucl Med. 2017;58(8):1330-1333.
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Vörös Z, Csík G, Herényi L, Kellermayer MS. Stepwise reversible nanomechanical buckling in a viral capsid. Nanoscale. 2017;9(3):1136-1143.
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Werry EL, King VA, Barron ML, Banister SD, Sokias R, Kassiou M. Derivatives of the pyrazolo[1,5-a]pyrimidine acetamide DPA-713 as translocator protein (TSPO) ligands and pro-apoptotic agents in human glioblastoma. Eur J Pharm Sci. 2017;96:186-192.
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Wiesmann M, Zinnhardt B, Reinhardt D, Eligehausen S, Wachsmuth L, Hermann S, Dederen PJ, Hellwich M, Kuhlmann MT, Broersen LM, Heerschap A, Jacobs AH, Kiliaan AJ. A specific dietary intervention to restore brain structure and function after ischemic stroke. Theranostics 2017; 7(2): 493-512.
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Wijasa TS, Sylvester M, Brocke-Ahmadinejad N, Kummer MP, Brosseron F, Gieselmann V, Heneka MT. Proteome profiling of s-nitrosylated synaptosomal proteins by isobaric mass tags. J Neurosci Methods. 2017;291:95-100.
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Wilkinson SM, Barron ML, O'Brien-Brown J, Janssen B, Stokes L, Werry EL, Chishty M, Skarratt KK, Ong JA, Hibbs DE, Vugts DJ, Fuller S, Windhorst AD, Kassiou M. Pharmacological evaluation of novel bioisosteres of an adamantanyl benzamide P2X7 receptor antagonist. ACS Chem Neurosci. 2017;8(11):2374-2380.
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Willekens SM, Van Weehaeghe D, Van Damme P, Van Laere K. Positron emission tomography in amyotrophic lateral sclerosis: Towards targeting of molecular pathological hallmarks. Eur J Nucl Med Mol Imaging. 2017;44(3):533-547.
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Wimberley C, Lavisse S, Brulon V, Peyronneau MA, Leroy C, Bodini B, Remy P, Stankoff B, Buvat I, Bottlaender M. Impact of endothelial TSPO on the quantification of 18F-DPA71. J Nucl Med. 2018;59(2):307-314.
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Wong ECN, Reekie TA, Werry EL, O'Brien-Brown J, Bowyer SL, Kassiou M. Pharmacological evaluation of a novel series of urea, thiourea and guanidine derivatives as P2X7 receptor antagonists. Bioorg Med Chem Lett. 2017;27(11):2439-2442.
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Zinnhardt B, Pigeon H, Thézé B, Viel T, Wachsmuth L, Fricke IB, Schelhaas S, Honold L, Schwegmann K, Wagner S, Faust A, Faber C, Kuhlmann MT, Hermann S, Schäfers M, Winkeler A, Jacobs AH. Combined PET imaging of the inflammatory tumor microenvironment identifies margins of unique radiotracer uptake. Cancer Res. 2017 Apr 15;77(8):1831-1841.
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