RH-NRU

Rigshospitalet - Neurobiology Research Unit, Copenhagen, Denmark

Group Description

Brief description of legal entity
The Capital Region of Denmark is one of five administrative units in Denmark. The region provides healthcare, mental healthcare, regional development and research for 1.6 million people and it employs 36,000 people. The major hospital within the region is Rigshospitalet that hosts the Neurobiology Research Unit (NRU) (www.nru.dk). NRU has a long history of research within receptor brain imaging, receptor binding, cellular characterization and quantification, tracer validation, kinetic modelling and data analysis. NRU employs approx. 35 researchers and is the central institution in the Centre for Integrated Molecular Brain Imaging (Cimbi, www.cimbi.org), which is founded on a collaboration between a number of research institutions in Copenhagen including the Danish Research Centre for Magnetic Resonance, the Department of Informatics and Mathematical Modelling at The Technical University of Denmark, The PET and Cyclotron Unit at Rigshospitalet and The Department of Medicinal Chemistry at the University of Copenhagen. The institutions involved in Cimbi research span many scientific fields and provide a strong foundation for the NRU research within molecular brain imaging, receptor binding, cellular characterization and quantification, tracer validation, kinetic modelling and data analysis. NRU and Cimbi are both chaired by Professor Gitte Moos Knudsen.

Main tasks
Molecular Brain Imaging research based on clinical and experimental studies and with a particular emphasis on data analytical approaches. Within this project, NRU will conduct imaging of patients with neurological disorders using single photon emission tomography (SPET) and [123I]CLINDE. In addition, NRU will conduct evaluation of the relationship between imaging probes in experimental models of neuroinflammation, and quantification of new radiotracers.

Participation in INMiND: WP3 / WP5 / WP7 / WP8 / WP11 / WP12.

Previous experience relevant to INMiND tasks

NRU has an international reputation in the areas of neuroimaging (MRI, PET, SPECT) in neuropsychiatric disorders, signal processing, and in translational neuroscience where the main focus is brain imaging in healthy subjects and in neuropsychiatric disorders, receptor immunohistochemistry and quantification, tracer validation, kinetic modelling and data analysis.


Rigshospitalet
Prof Gitte KNUDSEN
INMiND Office
European Institute for Molecular Imaging (EIMI) Waldeyerstr. 15
· 48149 Münster
Tel: +49 251 83 49300 · Fax: +49 251 83 49313
E-Mail: