UA

Universiteit Antwerpen, Antwerpen, Belgium

Group Description

Brief description of legal entity
The legal entity to which the Bio-Imaging Lab (BIL) belongs is the University of Antwerp (UA) which has 3,900 employees and 13,000 students, and situated in the north of Belgium. The core business of the Bio-Imaging lab is high-resolution neuroMRI focusing on neurodegeneration, neuronal plasticity and neuromodulation on the one hand and auditory processing, memory and learning on the other hand. The research is performed on rat and mouse models for different neuropathologies and on songbirds as a model for extreme neuronal plasticity, auditory processing and learning. The lab is also core facility for in vivo small animal imaging of the University of Antwerp for academic and industrial collaborations. The lab has a two 7Tesla 16 cm and one 9,4Tesla 20 cm horizontal bore MRI systems both from Bruker (Germany), a 4.7Tesla desktop from MRSolutions, is equipped with a Bioluminescence camera from Biospace (France) and has access to microCT, microPET equipment and image processing expertise available within other research teams of the University of Antwerp with whom they represent the EGAMI consortium within the University of Antwerp.

Main tasks
As such the Bio-Imaging lab will contribute to the project as an imaging partner, assessing the included animal models of ND and NI by means of MRI and BLI in the early stage and by evaluating new probes during the later stages.
The lab represented by Annemie Van der Linden is P7 in the INMiND project, WP leader of WP6 and responsible for neuroMRI training in Antwerp.

Participation in INMiND: WP1 / WP2 / WP4 / WP5 / WP6 (leader) / WP7 / WP10 / WP12.

Previous experience relevant to INMiND tasks

The Bio-Imaging Lab (BIL) has expertise in imaging neurodegenerative models including AD, PD, ALS and HD. As such we are partner in an EC Collaborative, Large-scale integrating project entitled ‘Nanoparticles for therapy and diagnosis of Alzheimer Disease’ (NAD) which focuses on the development of nanoparticles that target amyloid and BIL operates as imaging partner to validate the developed nanoparticles. BIL was also partner and steering member in DIMI, an EC NoE where they were responsible for the WP on phenotyping animal models on neurodegeneration and in RATStream, an EC STREP on phenotyping transgenic rat models for Huntington’s, Parkinson’s Disease and Cerebellar Ataxia.


University of Amsterdam
Prof Annemie VAN DER LINDEN
INMiND Office
European Institute for Molecular Imaging (EIMI) Waldeyerstr. 15
· 48149 Münster
Tel: +49 251 83 49300 · Fax: +49 251 83 49313
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