BV-Cyclo

BV-Cyclotron VU, Amsterdam, The Netherlands

Group Description

Brief description of legal entity
BV Cyclotron VU (www.cyclotron.nl) is a private company located at the campus of VU University Medical Centre in Amsterdam, the Netherlands. Since 1987 BV Cyclotron VU has been producing SPECT and PET radiopharmaceuticals and PET radiochemicals for medical diagnostics and research. BV Cyclotron VU produces [18F]FDG, [18F]Fluoromethylcholine, 124I, 89Zr, and other [18F]-labelled compounds for the PET community, and [81Rb/81mKr]-generators for the SPECT community. BV Cyclotron is fully licensed for manufacturing and distribution of PET tracers, both for marketed drugs as well as investigational medicinal products, within the Netherlands and internationally. With four cyclotrons and several clean rooms it is one of the largest cyclotron sites in Europe. BV Cyclotron VU’s mission is to make a wide range of PET compounds available. Their goal is to make products of the highest pharmaceutical quality and to be a highly reliable supplier of those products. To achieve this goal, BV Cyclotron VU continuously invests in the best equipment available on the market. Partners as Covidien, IBA and Perkin Elmer distribute their products. The department of Nuclear Medicine and PET Research of the VU University Medical Centre is the partner in research and development of new PET tracers. In line with that, BV Cyclotron VU was co-organizing the 19th International Symposium on Radiopharmaceutical Sciences in Amsterdam, 2011.

Main tasks
BV Cyclotron VU main focus will be the development of new molecular imaging probes, especially [11C]- and [18F]-labelled PET-tracers. A further task is the ‘large-scale’ production of these new radiotracers and existing ones like [18F]DPA714 to facilitate multi-centre preclinical and clinical imaging studies.

Participation in INMiND:  WP3

Previous experience relevant to INMiND tasks

Production of radionuclides for research and commercial applications. BV Cyclotron has also experience in developing new radiopharmaceuticals and subsequently up-scaling the labelling procedures for multi-centre trials and ‘commercial’ production. BV Cyclotron is involved in a large national project on the development of new diagnostic tracers for Alzheimer’s disease (LeARN, www.ctmm.nl).


BV Cyclotron VU

Principal Investigator

Erik VAN LIER, MASc
INMiND Office
European Institute for Molecular Imaging (EIMI) Waldeyerstr. 15
· 48149 Münster
Tel: +49 251 83 49300 · Fax: +49 251 83 49313
E-Mail: