• Research Areas

    • Small-angle X-ray and neutron scattering (SAXS/SANS)
    • static and dynamic light scattering (SLS / DLS)
    • absorption and fluorescence spectroscopy
    • Tensiometry
    • Analysis of the structure of colloids in aqueous solution by different analytical methods:
  • CV


    PhD in biophysical chemistry, Bielefeld University
    Master of Science in physical chemistry, University of Bielefeld
    Bachelor of Science in biochemistry, University of Bielefeld


    akademische Rätin, Physical chemistry, WWU Münster
    research fellow, Biophysical chemistry, University of Bielefeld


    Soft Matter poster prize at the 33rd Conference of the European Colloid and Interface Society – Soft Matter, Royal Society of Chemistry
    advancement award of the Friedrich Wilhelm Helweg-foundation – University of Bielefeld
  • Publications

    • Abitaev K, Qawasmi Y, Atanasova P, Dargel C, Bill J, Hellweg T, Sottmann T. . ‘Adjustable polystyrene nanoparticle templates for the production of mesoporous foams and ZnO inverse opals.’ Colloid and Polymer Science 299, No. 2: 243-258. doi: 10.1007/s00396-020-04791-5.
    • Dargel C, Gräbitz-Bräuer F, Geisler R, Fandrich P, Hannappel Y, Porcar L, Hellweg T. . ‘Stable DOPG/Glycyrrhizin Vesicles with a Wide Range of Mixing Ratios: Structure and Stability as Seen by Scattering Experiments and Cryo-TEM.’ Molecules 26, No. 16: 4959. doi: 10.3390/molecules26164959.
    • Dargel C, Hannappel Y, Hellweg T. . ‘Heating-Induced DMPC/Glycyrrhizin Bicelle-to-Vesicle Transition: A X-Ray Contrast Variation Study.’ Biophysical Journal 118, No. 10: 2411-2425. doi: 10.1016/j.bpj.2020.03.022.
    • Dirksen M, Dargel C, Meier L, Brändel T, Hellweg T. . ‘Smart microgels as drug delivery vehicles for the natural drug aescin: Uptake, release and interactions.’ Colloid and Polymer Science 298: 505-518. doi: 10.1007/s00396-020-04632-5.
    • Geisler R, Dargel C, Hellweg T. . ‘The biosurfactant beta-aescin: a review on the physico-chemical properties and its interaction with lipid model membranes and Langmuir monolayers.’ Molecules 25, No. 1: 117. doi: 10.3390/molecules25010117.
    • Dieterich S, Prèvost S, Dargel C, Sottmann T, Giesselmann F. . ‘Synergistic structures in lyotropic lamellar gels.’ Soft Matter 16, No. 45: 10268-10279. doi: 10.1039/D0SM01473G.
    • Dargel C, Geisler R, Hannappel Y, Kemker I, Sewald N, Hellweg T. . ‘Self-assembly of the bio-surfactant aescin in solution: A small-angle X-ray scattering and Fluorescence study.’ Colloids and Interfaces 3, No. 2: 47. doi: 10.3390/colloids3020047.
    • Sreij R, Dargel C, Schweins R, Prèvost S,Dattani R, Hellweg T. . ‘Aescin-cholesterol complexes in DMPC model membranes: a DSC and temperature-dependent scattering study.’ Scientific Reports 9, No. 1: 1-15. doi: 10.1038/s41598-019-41865-z.
    • Sreij R, Dargel C, Hannappel Y, Jestin J, Prèvost S, Dattani R, Wrede O, Hellweg T. . ‘Temperature dependent self-organization of DMPC membranes promoted by intermediate amounts of the saponin aescin.’ Biochimica et Biophysica Acta (BBA)-Biomembranes 1861, No. 5: 897-906. doi: 10.1016/j.bbamem.2019.01.015.
    • Sreij R, Prévost S, Dargel C, Dattani R, Hertle Y, Wrede O, Hellweg T. . ‘Interaction of the saponin aescin with ibuprofen in DMPC model membranes.’ Molecular pharmaceutics 15, No. 10: 4446-4461. doi: 10.1021/acs.molpharmaceut.8b00421.
    • Sreij R, Dargel C, Geisler, P, Hertle Y, Radulescu A, Pasini S, Perez J, Moleiro LH, Hellweg T. . ‘DMPC vesicle structure and dynamics in the presence of low amounts of the saponin aescin.’ Physical Chemistry Chemical Physics 20, No. 14: 9070-9083. doi: 10.1039/C7CP08027A.
    • Sreij R, Dargel C, Moleiro, LH, Monroy, F, Hellweg, T. . ‘Aescin incorporation and nanodomain formation in DMPC model membranes.’ Langmuir 33, No. 43: 12351-12361. doi: 10.1021/acs.langmuir.7b02933.