Sarah Maskri

Topics of research:

The aim of my PhD thesis is to understand the binding mode of the available KCa3.1 and HCN ion channel modulators based on MD simulations, structural modelling and experimental validation. Therefore, I will conduct a detailed study using structure-based design and virtual screening approaches for the development and identification of new modulators. Furthermore, I also work with G protein-coupled receptor (GPCRs) with a focus on the formly peptide receptor (FPR) class. The aim is to provide reliable conformations using homology modelling and MD simulations and to propose binding positions for the design of new ligands.

  • Curriculum vitae