These immune cells respond to a stimulus; they redistribute part of their cytoskeleton (red) to the right. The central portion of the cytoskeleton (green) aligns along the direction of cell migration. Immunofluorescence microscopy.
© Marc Wolf, Johannes Roth

Research Area A: Individual Cells

How Cells Move Forwards

Cells divide, move in directed manners within an organism, and develop into different tissues and organs. CiM scientists investigate mechanisms underlying these processes and how genes and molecules determine the cells' behaviour. This basic knowledge is important for understanding how new organisms develop and function normally, and how diseases arise and can eventually be treated.

Scientific Concept

Individual cells represent the first level of cellular complexity to be studied in the Cells-in-Motion Cluster of Excellence (CiM): Research Area A aims at deciphering fundamental principles of cell-fate programmes and their impact on basic cellular features, especially those relevant for the movement and recruitment of cells to specific tissues. The programming and directed movement of cells are strongly linked and interdependent, since establishment of a defined cellular fate is necessary to ‘equip’ cells with the machinery required to induce cell shape changes, motility, functional polarity and directed migration. CiM will cover these aspects by analysing the behaviour of stem and germ cells, immune and tumour cells, and neurons in physiological and pathophysiological scenarios (A.1, A.2, A.3, A.4). These approaches are uniquely strengthened by expertise in Münster in synthetic and pharmaceutical chemistry that permit novel non-genetic labelling strategies (A.5) by exploiting cell-specific molecular targets identified in A.1-A.4, and are complemented by laser-based label-free imaging strategies developed in A.3. Mathematics is applied to unbiasedly and quantitatively track and predict subcellular dynamics, cell shape changes and the direction and speed of migration (A.6). In parallel, the field will be expanded to macroscopic imaging strategies, bridging analyses of individual cells in simple organisms to more complex systems/organisms.

Scientific Publications

Accepted for publication

Metternich JB, Mudd RJ, Gilmour R. Flavins in Photochemistry. Science of Synthesis: accepted for publication.


Ahmed W, Fodor E, Almonacid M, Bussonnier M, Verlhac M-H, Gov N, Visco P, Wijland F van, Betz T. Active mechanics reveal molecular-scale force kinetics in living oocytes. Biophysical Journal 2018;114: 1-13. Abstract
Ahmetspahic D, Schwarte K, Ambree O, Burger C, Falcone V, Seiler K, Kooybaran MR, Grosse L, Roos F, Scheffer J, Jorgens S, Koelkebeck K, Dannlowski U, Arolt V, Scheu S, Alferink J. Altered B Cell Homeostasis in Patients with Major Depressive Disorder and Normalization of CD5 Surface Expression on Regulatory B Cells in Treatment Responders. J Neuroimmune Pharmacol 2018;13: 90-99. Abstract
Ali S, Hoven A, Dress RJ, Schaal H, Alferink J, Scheu S. Identification of a novel Dlg2 isoform differentially expressed in IFNbeta-producing plasmacytoid dendritic cells. BMC Genomics 2018;19: 194. Abstract
Anhauser L, Muttach F, Rentmeister A. Reversible modification of DNA by methyltransferase-catalyzed transfer and light-triggered removal of photo-caging groups. Chem Commun 2018;54: 449-451. Abstract
Axer A, Hermann S, Kehr G, Clases D, Karst U, Fischer-Riepe L, Roth J, Fobker M, Schafers M, Gilmour R, Faust A. Harnessing the Maltodextrin Transport Mechanism for Targeted Bacterial Imaging: Structural Requirements for Improved in vivo Stability in Tracer Design. ChemMedChem 2018;13: 241-250. Abstract
Beati H, Peek I, Hordowska P, Honemann-Capito M, Glashauser J, Renschler FA, Kakanj P, Ramrath A, Leptin M, Luschnig S, Wiesner S, Wodarz A. The adherens junction-associated LIM domain protein Smallish regulates epithelial morphogenesis. J Cell Biol 2018;217: 1079-1095. Abstract
Berh D, Scherzinger A, Otto N, Jiang X, Klambt C, Risse B. Automatic non-invasive heartbeat quantification of Drosophila pupae. Comput Biol Med 2018;93: 189-199. Abstract
Brenker C, Schiffer C, Wagner IV, Tuttelmann F, Ropke A, Rennhack A, Kaupp UB, Strünker T. Action of steroids and plant triterpenoids on CatSper Ca(2+) channels in human sperm. Proc Natl Acad Sci U S A 2018;115: E344-E346. Abstract
Burger M, Dirks H, Schönlieb C-B. A Variational Model for Joint Motion Estimation and Image Reconstruction. SIAM J. Imaging Sci. 2018;11: 94-128. Abstract
Burger M, Düring B, Kreusser LM, Markowich PA, Schönlieb C-B. Pattern formation of a nonlocal, anisotropic interaction model. Math. Models Methods Appl. Sci. 2018;28: 409-451. Abstract
Clason C, Tameling C, Wirth B. Vector-Valued Multibang Control of Differential Equations. SIAM J. Control Optim. 2018;56: 2295-2326. Abstract
Delcanale P, Galstyan A, Daniliuc CG, Grecco HE, Abbruzzetti S, Faust A, Viappiani C, Strassert CA. Oxygen-Insensitive Aggregates of Pt(II) Complexes as Phosphorescent Labels of Proteins with Luminescence Lifetime-Based Readouts. ACS Appl Mater Interfaces 2018: epub. Abstract
Dreier A-L, Matsnev AV, Thrasher JS, Haufe G. Syn-selective silicon Mukaiyama-type aldol reactions of (pentafluoro-lambda(6)-sulfanyl)acetic acid esters with aldehydes. Beilstein J Org Chem 2018;14: 373-380. Abstract
Fassbender SI, Metternich JB, Gilmour R. Spatiotemporal Control of Pre-existing Alkene Geometry: A Bio-Inspired Route to 4-Trifluoromethyl-2H-chromenes. Org Lett 2018;20: 724-727. Abstract
Grosche J, Meissner J, Eble JA. More than a syllable in fib-ROS-is: The role of ROS on the fibrotic extracellular matrix and on cellular contacts. Mol Aspects Med 2018: epub. Abstract
Gruner MC, Niemann S, Faust A, Strassert CA. Axially Decorated Si(IV) -phthalocyanines Bearing Mannose- or Ammonium-conjugated Siloxanes: Comparative Bacterial Labeling and Photodynamic Inactivation. Photochem Photobiol 2018: epub. Abstract
Hartstock K, Nilges BS, Ovcharenko A, Cornelissen NV, Pullen N, Lawrence-Dorner A-M, Leidel SA, Rentmeister A. Enzymatic or In Vivo Installation of Propargyl Groups in Combination with Click Chemistry for the Enrichment and Detection of Methyltransferase Target Sites in RNA. Angew Chem Int Ed Engl 2018;57: 6342-6346. Abstract
Heeren B, Rumpf M, Wirth B. Variational time discretization of Riemannian splines. IMA Journal of Numerical Analysis 2018;00: 1–44. Abstract
Herzmann S, Gotzelmann I, Reekers L-F, Rumpf S. Spatial regulation of microtubule disruption during dendrite pruning in Drosophila. Development 2018;145: epub. Abstract
Kahms M, Klingauf J. Novel pH-Sensitive Lipid Based Exo-Endocytosis Tracers Reveal Fast Intermixing of Synaptic Vesicle Pools. Front Cell Neurosci 2018;12: 18. Abstract
Kieser TJ, Santschi N, Nowack L, Kehr G, Kuhlmann T, Albrecht S, Gilmour R. Single Site Fluorination of the GM4 Ganglioside Epitope Upregulates Oligodendrocyte Differentiation. ACS Chem Neurosci 2018;9: 1159-1165. Abstract
Kovac S, Alferink J, Ahmetspahic D, Arolt V, Melzer N. [Update on anti-N-methyl-D-aspartate receptor encephalitis]. Nervenarzt 2018;89: 99-112. Abstract
Lima AM, Wegner SV, Martins Cavaco AC, Estevao-Costa MI, Sanz-Soler R, Niland S, Nosov G, Klingauf J, Spatz JP, Eble JA. The spatial molecular pattern of integrin recognition sites and their immobilization to colloidal nanobeads determine alpha2beta1 integrin-dependent platelet activation. Biomaterials 2018;167: 107-120. Abstract
Loison O, Weitkunat M, Kaya-Copur A, Nascimento Alves C, Matzat T, Spletter ML, Luschnig S, Brasselet S, Lenne P-F, Schnorrer F. Polarization-resolved microscopy reveals a muscle myosin motor-independent mechanism of molecular actin ordering during sarcomere maturation. PLoS Biol 2018;16: e2004718. Abstract
Malhotra D, Shin J, Solnica-Krezel L, Raz E. Spatio-temporal regulation of concurrent developmental processes by generic signaling downstream of chemokine receptors. Elife 2018;7: epub. Abstract
Metternich JB, Sagebiel S, Luckener A, Lamping S, Ravoo BJ, Gilmour R. Covalent Immobilization of (-)-Riboflavin on Polymer Functionalized Silica Particles: Application in the Photocatalytic E-->Z Isomerization of Polarized Alkenes. Chemistry 2018;24: 4228-4233. Abstract
Michels T, Berh D, Jiang X. An RJMCMC-based method for tracking and resolving collisions of Drosophila Larvae. IEEE/ACM Transactions on Computational Biology and Bioinformatics 2018: epub. Abstract
Molloy JJ, Metternich JB, Daniliuc CG, Watson AJB, Gilmour R. Contra-Thermodynamic, Photocatalytic E-->Z Isomerization of Styrenyl Boron Species: Vectors to Facilitate Exploration of Two-Dimensional Chemical Space. Angew Chem Int Ed Engl 2018;57: 3168-3172. Abstract
Morack T, Gilmour R. Classic reaction re-engineered through molecular face recognition. Nature 2018;556: 438-439. Abstract
Morack T, Metternich JB, Gilmour R. Vitamin Catalysis: Direct, Photocatalytic Synthesis of Benzocoumarins via (-)-Riboflavin-Mediated Electron Transfer. Org Lett 2018;20: 1316-1319. Abstract
Nelson JO, Forster D, Frizzell KA, Luschnig S, Metzstein MM. Multiple Nonsense-Mediated mRNA Processes Require Smg5 in Drosophila. Genetics 2018: epub. Abstract
Pfeiffer J, Tarbashevich K, Bandemer J, Palm T, Raz E. Rapid progression through the cell cycle ensures efficient migration of primordial germ cells - The role of Hsp90. Dev Biol 2018;436: 84-93. Abstract
Rakers L, Grill D, Matos ALL, Wulff S, Wang D, Börgel J, Körsgen M, Arlinghaus HF, Galla H-J, Gerke V, Glorius F. Addressable Cholesterol Analogs for Live Imaging of Cellular Membranes. Cell Chem Biol 2018: epub. Abstract
Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, De Tullio P, Sin O, Shostak K, Schmitz S, Piepers J, Ghesquiere B, Karim L, Charloteaux B, Jamart D, Florin A, Lambert C, Rorive A, Jerusalem G, Leucci E, Dewaele M, Vooijs M, Leidel SA, Georges M, Voz M, Peers B, Buttner R, Marine J-C, Chariot A, Close P. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature 2018;558: 605-609. Abstract
Rieger S, Würthwein T, Sparenberg K, Boller K-J, Fallnich C. Density matrix study of ground state depletion towards sub-diffraction-limited spontaneous Raman scattering spectroscopy. J Chem Phys 2018;148: 204110. Abstract
Sadurni A, Gilmour R. Stereocontrolled Synthesis of 2-Fluorinated C-Glycosides. Eur. J. Org. Chem. 2018: epub. Abstract
Sadurni A, Kehr G, Ahlqvist M, Wernevik J, Sjogren HP, Kankkonen C, Knerr L, Gilmour R. Fluorine-Directed Glycosylation Enables the Stereocontrolled Synthesis of Selective SGLT2 Inhibitors for Type II Diabetes. Chemistry 2018;24: 2832-2836. Abstract
Saha T, Galic M. Self-organization across scales: from molecules to organisms. Phil. Trans. R. Soc. B 2018;373Abstract
Scheidt F, Thiehoff C, Yilmaz G, Meyer S, Daniliuc CG, Kehr G, Gilmour R. Fluorocyclisation via I(I)/I(III) catalysis: a concise route to fluorinated oxazolines. Beilstein J. Org. Chem. 2018;14: 1021-1027. Abstract
Schuermann S, Steffes G, Manikowski D, Kastl P, Malkus U, Bandari S, Ohlig S, Ortmann C, Rebollido-Rios R, Otto M, Nusse H, Hoffmann D, Klambt C, Galic M, Klingauf J, Grobe K. Proteolytic processing of palmitoylated Hedgehog peptides specifies the 3-4 intervein region of the Drosophila wing. Elife 2018;7: epub. Abstract
Susek KH, Korpos E, Huppert J, Wu C, Savelyeva I, Rosenbauer F, Muller-Tidow C, Koschmieder S, Sorokin L. Bone marrow laminins influence hematopoietic stem and progenitor cell cycling and homing to the bone marrow. Matrix Biol 2018;67: 47-62. Abstract
Termathe M, Leidel SA. The Uba4 domain interplay is mediated via a thioester that is critical for tRNA thiolation through Urm1 thiocarboxylation. Nucleic Acids Res 2018;46: 5171-5181. Abstract
Teschers CS, Daniliuc CG, Kehr G, Gilmour R. Conformational control enabled by the fluorine gauche effect in a model of the β 2 -AR agonist salbutamol (Ventolin™). J. Fluor. Chem 2018;210: 1-5. Abstract
Wallmeyer B, Trinschek S, Yigit S, Thiele U, Betz T. Collective Cell Migration in Embryogenesis Follows the Laws of Wetting. Biophys J 2018;114: 213-222. Abstract


Attieh Y, Clark AG, Grass C, Richon S, Pocard M, Mariani P, Elkhatib N, Betz T, Gurchenkov B, Vignjevic DM. Cancer-associated fibroblasts lead tumor invasion through integrin-beta3-dependent fibronectin assembly. J Cell Biol 2017;216: 3509-3520. Abstract
Bachmann A-L, Mootz HD. N-terminal chemical protein labeling using the naturally split GOS-TerL intein. J Pept Sci 2017;23: 624-630. Abstract
Bartels K, Schinor B, Haufe G. Diastereoselectivity of cyclopropanation of substituted α-fluorostyrenes versus styrenes by different methods. Journal of Fluorine Chemistry 2017;203: 200-205. Abstract
Berh D, Risse B, Michels T, Otto N, Jiang X, Klambt C. An FIM-Based Long-Term In-Vial Monitoring System for Drosophila Larvae. IEEE Trans. Biomed. Eng. 2017;64: 1862-1874. Abstract
Berkels B, Wirth B. Joint denoising and distortion correction of atomic scale scanning transmission electron microscopy images. Inverse Problems 2017;33: 095002. Abstract
Bian A, Scherzinger A, Jiang X. An enhanced multi-label random walk for biomedical image segmentation using statistical seed generation. In: Blanc-Talon et al. (Eds.): ACIVS 2017, LNCS 10617 2017;Springer, Cham: 748–760. Abstract
Biesemann A, Gorontzi A, Barr F, Gerke V. Rab35 protein regulates evoked exocytosis of endothelial Weibel-Palade bodies. J Biol Chem 2017;292: 11631-11640. Abstract
Bodzeta A, Kahms M, Klingauf J. The Presynaptic v-ATPase Reversibly Disassembles and Thereby Modulates Exocytosis but Is Not Part of the Fusion Machinery. Cell Rep 2017;20: 1348-1359. Abstract
Borrello MT, Schinor B, Bartels K, Benelkebir H, Pereira S, Al-Jamal WT, Douglas L, Duriez PJ, Packham G, Haufe G, Ganesan A. Fluorinated tranylcypromine analogues as inhibitors of lysine-specific demethylase 1 (LSD1, KDM1A). Bioorg Med Chem Lett 2017;27: 2099-2101. Abstract
Boye TL, Maeda K, Pezeshkian W, Sonder SL, Haeger SC, Gerke V, Simonsen AC, Nylandsted J. Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair. Nat Commun 2017;8: 1623. Abstract
Brancolini A, Wirth B. Optimal Energy Scaling for Micropatterns in Transport Networks. SIAM J. Math. Anal. 2017;49: 311-359. Abstract
Braun DA, Rao J, Mollet G, Schapiro D, Daugeron M-C, Tan W, Gribouval O, Boyer O, Revy P, Jobst-Schwan T, Schmidt JM, Lawson JA, Schanze D, Ashraf S, Ullmann JFP, Hoogstraten CA, Boddaert N, Collinet B, Martin G, Liger D, Lovric S, Furlano M, Guerrera IC, Sanchez-Ferras O, Hu JF, Boschat A-C, Sanquer S, Menten B, Vergult S, De Rocker N, Airik M, Hermle T, Shril S, Widmeier E, Gee HY, Choi W-I, Sadowski CE, Pabst WL, Warejko JK, Daga A, Basta T, Matejas V, Scharmann K, Kienast SD, Behnam B, Beeson B, Begtrup A, Bruce M, Ch'ng G-S, Lin S-P, Chang J-H, Chen C-H, Cho MT, Gaffney PM, Gipson PE, Hsu C-H, Kari JA, Ke Y-Y, Kiraly-Borri C, Lai W-M, Lemyre E, Littlejohn RO, Masri A, Moghtaderi M, Nakamura K, Ozaltin F, Praet M, Prasad C, Prytula A, Roeder ER, Rump P, Schnur RE, Shiihara T, Sinha MD, Soliman NA, Soulami K, Sweetser DA, Tsai W-H, Tsai J-D, Topaloglu R, Vester U, Viskochil DH, Vatanavicharn N, Waxler JL, Wierenga KJ, Wolf MTF, Wong S-N, Leidel SA, Truglio G, Dedon PC, Poduri A, Mane S, Lifton RP, Bouchard M, Kannu P, Chitayat D, Magen D, Callewaert B, van Tilbeurgh H, Zenker M, Antignac C, Hildebrandt F. Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly. Nat Genet 2017;49: 1529-1538. Abstract
Brinkmann M, Hellwig T, Fallnich C. Optical parametric chirped pulse oscillation. Opt. Express 2017;25: 12884. Abstract
Bruna M, Burger M, Ranetbauer H, Wolfram M-T. Cross-Diffusion Systems with Excluded-Volume Effects and Asymptotic Gradient Flow Structures. J Nonlinear Sci 2017;27: 687-719. Abstract
Bruser L, Bogdan S. Adherens Junctions on the Move-Membrane Trafficking of E-Cadherin. Cold Spring Harb Perspect Biol 2017;9: a029140. Abstract
Buerger C, Redlich R, Grotegerd D, Meinert S, Dohm K, Schneider I, Zaremba D, Forster K, Alferink J, Bolte J, Heindel W, Kugel H, Arolt V, Dannlowski U. Differential Abnormal Pattern of Anterior Cingulate Gyrus Activation in Unipolar and Bipolar Depression: an fMRI and Pattern Classification Approach. Neuropsychopharmacology 2017;42: 1399-1408. Abstract
Bulk E, Kramko N, Liashkovich I, Glaser F, Schillers H, Schnittler HJ, Oberleithner H, Schwab A. KCa31 channel inhibition leads to an ICAM-1 dependent increase of cell-cell adhesion between A549 lung cancer and HMEC-1 endothelial cells. Oncotarget 2017;8: 112268-112282. Abstract
Burger M, Elvetun OL, Schlottbom M. Analysis of the Diffuse Domain Method for Second Order Elliptic Boundary Value Problems. Found Comput Math 2017;17: 627-674. Abstract
Caviglia S, Flores-Benitez D, Lattner J, Luschnig S, Brankatschk M. Rabs on the fly: Functions of Rab GTPases during development. Small GTPases 2017: 1-10. Abstract
Chehab T, Santos NC, Holthenrich A, Koerdt SN, Disse J, Schuberth C, Nazmi AR, Neeft M, Koch H, Man KNM, Wojcik SM, Martin TFJ, van der Sluijs P, Brose N, Gerke V. A novel Munc13-4/S100A10/annexin A2 complex promotes Weibel-Palade body exocytosis in endothelial cells. Mol Biol Cell 2017;28: 1688-1700. Abstract
Clases D, Birka M, Sperling M, Faust A, Karst U. Isobaric dilution analysis as a calibration tool for long lived radionuclides in ICP-MS. J Trace Elem Med Biol 2017;40: 97-103. Abstract
Dai B, Grau M, Juilland M, Klener P, Horing E, Molinsky J, Schimmack G, Aukema SM, Hoster E, Vogt N, Staiger AM, Erdmann T, Xu W, Erdmann K, Dzyuba N, Madle H, Berdel WE, Trneny M, Dreyling M, Johrens K, Lenz P, Rosenwald A, Siebert R, Tzankov A, Klapper W, Anagnostopoulos I, Krappmann D, Ott G, Thome M, Lenz G. B-cell receptor-driven MALT1 activity regulates MYC signaling in mantle cell lymphoma. Blood 2017;129: 333-346. Abstract
de Vries WC, Grill D, Tesch M, Ricker A, Nusse H, Klingauf J, Studer A, Gerke V, Ravoo BJ. Reversible Stabilization of Vesicles: Redox-Responsive Polymer Nanocontainers for Intracellular Delivery. Angew Chem Int Ed Engl 2017;56: 9603-9607. Abstract
Dreier A-L, Beutel B, Muck-Lichtenfeld C, Matsnev AV, Thrasher JS, Haufe G. Synthesis of alpha-(Pentafluorosulfanyl)- and alpha-(Trifluoromethyl)-Substituted Carboxylic Acid Derivatives by Ireland-Claisen Rearrangement. J Org Chem 2017;82: 1638-1648. Abstract
Ebnet K, Kummer D, Steinbacher T, Singh A, Nakayama M, Matis M. Regulation of cell polarity by cell adhesion receptors. Semin Cell Dev Biol 2017Abstract
Erdmann T, Klener P, Lynch JT, Grau M, Vockova P, Molinsky J, Tuskova D, Hudson K, Polanska UM, Grondine M, Mayo M, Dai B, Pfeifer M, Erdmann K, Schwammbach D, Zapukhlyak M, Staiger AM, Ott G, Berdel WE, Davies BR, Cruzalegui F, Trneny M, Lenz P, Barry ST, Lenz G. Sensitivity to PI3K and AKT inhibitors is mediated by divergent molecular mechanisms in subtypes of DLBCL. Blood 2017;130: 310-322. Abstract
Feskov IO, Chernykh AV, Kondratov IS, Klyachina M, Daniliuc CG, Haufe G. Cyclobutyl-Containing Rigid Analogues of Threonine: Synthesis and Physical Chemical Properties. J Org Chem 2017;82: 12863-12868. Abstract
Goudarzi M, Tarbashevich K, Mildner K, Begemann I, Garcia J, Paksa A, Reichman-Fried M, Mahabaleshwar H, Blaser H, Hartwig J, Zeuschner D, Galic M, Bagnat M, Betz T, Raz E. Bleb Expansion in Migrating Cells Depends on Supply of Membrane from Cell Surface Invaginations. Dev Cell 2017;43: 577-587.e5. Abstract
Grah JS, Harrington JA, Koh SB, Pike JA, Schreiner A, Burger M, Schonlieb C-B, Reichelt S. Mathematical imaging methods for mitosis analysis in live-cell phase contrast microscopy. Methods 2017;115: 91-99. Abstract
Gross-Thebing T, Yigit S, Pfeiffer J, Reichman-Fried M, Bandemer J, Ruckert C, Rathmer C, Goudarzi M, Stehling M, Tarbashevich K, Seggewiss J, Raz E. The Vertebrate Protein Dead End Maintains Primordial Germ Cell Fate by Inhibiting Somatic Differentiation. Developmental Cell 2017;43: 704-715.e5. Abstract
Herzmann S, Krumkamp R, Rode S, Kintrup C, Rumpf S. PAR-1 promotes microtubule breakdown during dendrite pruning in Drosophila. EMBO J 2017;36: 1981-1991. Abstract
Hofschroer V, Koch KA, Ludwig FT, Friedl P, Oberleithner H, Stock C, Schwab A. Extracellular protonation modulates cell-cell interaction mechanics and tissue invasion in human melanoma cells. Sci Rep 2017;7: 42369. Abstract
Holstein JM, Muttach F, Schiefelbein SHH, Rentmeister A. Dual 5' Cap Labeling Based on Regioselective RNA Methyltransferases and Bioorthogonal Reactions. Chemistry 2017;23: 6165-6173. Abstract
Horner F, Meissner R, Polali S, Pfeiffer J, Betz T, Denz C, Raz E. Holographic optical tweezers-based in vivo manipulations in zebrafish embryos. J Biophotonics 2017;10: 1492-1501. Abstract
Jakobsson ME, Malecki J, Nilges BS, Moen A, Leidel SA, Falnes PO. Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation. Nucleic Acids Res 2017;45: 8239-8254. Abstract
Jerabek S, Ng CK, Wu G, Arauzo-Bravo MJ, Kim K-P, Esch D, Malik V, Chen Y, Velychko S, MacCarthy CM, Yang X, Cojocaru V, Scholer HR, Jauch R. Changing POU dimerization preferences converts Oct6 into a pluripotency inducer. EMBO Rep 2017;18: 319-333. Abstract
Jungfleisch J, Nedialkova DD, Dotu I, Sloan KE, Martinez-Bosch N, Bruning L, Raineri E, Navarro P, Bohnsack MT, Leidel SA, Diez J. A novel translational control mechanism involving RNA structures within coding sequences. Genome Res 2017;27: 95-106. Abstract
Kellermann SJ, Rentmeister A. A FACS-based screening strategy to assess sequence-specific RNA-binding of Pumilio protein variants in E coli. Biol Chem 2017;398: 69-75. Abstract
Koelkebeck K, Liedtke C, Kohl W, Alferink J, Kret ME. Attachment style moderates theory of mind abilities in depression. J Affect Disord 2017;213: 156-160. Abstract
Koerdt SN, Gerke V. Annexin A2 is involved in Ca2+-dependent plasma membrane repair in primary human endothelial cells. Biochim Biophys Acta 2017;1864: 1046-1053. Abstract
Kondratov IS, Logvinenko IG, Tolmachova NA, Morev RN, Kliachyna MA, Clausen F, Daniliuc CG, Haufe G. Synthesis and physical chemical properties of 2-amino-4-(trifluoromethoxy)butanoic acid - a CF3O-containing analogue of natural lipophilic amino acids. Org Biomol Chem 2017;15: 672-679. Abstract
Leufken J, Niehues A, Sarin LP, Wessel F, Hippler M, Leidel SA, Fufezan C. pyQms enables universal and accurate quantification of mass spectrometry data. Mol Cell Proteomics 2017;16: 1736-1745. Abstract
Lutz M, Schulze AB, Rebber E, Wiebe S, Zoubi T, Grauer OM, Kessler T, Kerkhoff A, Lenz G, Berdel WE. Progressive Multifocal Leukoencephalopathy after Ibrutinib Therapy for Chronic Lymphocytic Leukemia. Cancer Res Treat 2017;49: 548-552. Abstract
Malecki J, Aileni VK, Ho AYY, Schwarz J, Moen A, Sorensen V, Nilges BS, Jakobsson ME, Leidel SA, Falnes PO. The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A). Nucleic Acids Res 2017;45: 4370-4389. Abstract
Martineau M, Guzman RE, Fahlke C, Klingauf J. VGLUT1 functions as a glutamate/proton exchanger with chloride channel activity in hippocampal glutamatergic synapses. Nat Commun 2017;8: 2279. Abstract
Metternich JB, Artiukhin DG, Holland MC, von Bremen-Kuhne M, Neugebauer J, Gilmour R. Photocatalytic E --> Z Isomerization of Polarized Alkenes Inspired by the Visual Cycle: Mechanistic Dichotomy and Origin of Selectivity. J Org Chem 2017;82: 9955-9977. Abstract
Mittal N, Guimaraes JC, Gross T, Schmidt A, Vina-Vilaseca A, Nedialkova DD, Aeschimann F, Leidel SA, Spang A, Zavolan M. The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan. Nat Commun 2017;8: 457. Abstract
Muttach F, Masing F, Studer A, Rentmeister A. New AdoMet Analogues as Tools for Enzymatic Transfer of Photo-Cross-Linkers and Capturing RNA-Protein Interactions. Chemistry 2017;23: 5988-5993. Abstract
Muttach F, Muthmann N, Reichert D, Anhäuser L, Rentmeister A. A benzylic linker promotes methyltransferase catalyzed norbornene transfer for rapid bioorthogonal tetrazine ligation. Chem. Sci. 2017;8: 7947-7953. Abstract
Muttach F, Muthmann N, Rentmeister A. Chemo-enzymatic modification of eukaryotic mRNA. Org Biomol Chem 2017;15: 278-284. Abstract
Nagel BM, Bechtold M, Rodriguez LG, Bogdan S. Drosophila WASH is required for integrin-mediated cell adhesion, cell motility and lysosomal neutralization. J Cell Sci 2017;130: 344-359. Abstract
Nielsen N, Kondratska K, Ruck T, Hild B, Kovalenko I, Schimmelpfennig S, Welzig J, Sargin S, Lindemann O, Christian S, Meuth SG, Prevarskaya N, Schwab A. TRPC6 channels modulate the response of pancreatic stellate cells to hypoxia. Pflugers Arch 2017;469: 1567-1577. Abstract
Opel N, Redlich R, Grotegerd D, Dohm K, Zaremba D, Meinert S, Burger C, Plumpe L, Alferink J, Heindel W, Kugel H, Zwanzger P, Arolt V, Dannlowski U. Prefrontal brain responsiveness to negative stimuli distinguishes familial risk for major depression from acute disorder. J Psychiatry Neurosci 2017;42: 160198. Abstract
Ortmeyer CP, Haufe G, Schwegmann K, Hermann S, Schafers M, Borgel F, Wunsch B, Wagner S, Hugenberg V. Synthesis and evaluation of a [18F]BODIPY-labeled caspase-inhibitor. Bioorg Med Chem 2017;25: 2167-2176. Abstract
Owlarn S, Klenner F, Schmidt D, Rabert F, Tomasso A, Reuter H, Mulaw MA, Moritz S, Gentile L, Weidinger G, Bartscherer K. Generic wound signals initiate regeneration in missing-tissue contexts. Nat Commun 2017;8: 2282. Abstract
Pedersen SF, Novak I, Alves F, Schwab A, Pardo LA. Alternating pH landscapes shape epithelial cancer initiation and progression: Focus on pancreatic cancer. Bioessays 2017;39Abstract
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Thyssen GM, Holtkamp M, Kaulfurst-Soboll H, Wehe CA, Sperling M, von Schaewen A, Karst U. Elemental bioimaging by means of LA-ICP-OES: investigation of the calcium, sodium and potassium distribution in tobacco plant stems and leaf petioles. Metallomics 2017;9: 676-684. Abstract
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Holstein JM, Anhauser L, Rentmeister A. Modifying the 5'-Cap for Click Reactions of Eukaryotic mRNA and To Tune Translation Efficiency in Living Cells. Angew Chem Int Ed Engl 2016;55: 10899-10903. Abstract
Holstein JM, Rentmeister A. Current covalent modification methods for detecting RNA in fixed and living cells. Methods 2016;98: 18-25. Abstract
Holstein JM, Stummer D, Rentmeister A. Enzymatic Modification of 5'-Capped RNA and Subsequent Labeling by Click Chemistry. Methods Mol Biol 2016;1428: 45-60. Abstract
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Metternich J, Gilmour R. Photocatalytic E → Z Isomerization of Alkenes. Synlett 2016;27: 2541-2552. Abstract
Metternich JB, Gilmour R. One Photocatalyst, n Activation Modes Strategy for Cascade Catalysis: Emulating Coumarin Biosynthesis with (-)-Riboflavin. J Am Chem Soc 2016;138: 1040-1045. Abstract
Molnár I, Holland M, Daniliuc C, Houk K, Gilmour R. Organocatalysis Intermediates as Platforms to Study Noncovalent Interactions: Integrating Fluorine Gauche Effects in Iminium Systems to Facilitate Acyclic Conformational Control. Synlett 2016;27: 1051-1055. Abstract
Molnar IG, Gilmour R. Catalytic Difluorination of Olefins. J Am Chem Soc 2016;138: 5004-5007. Abstract
Molnár IG, Thiehoff C, Holland MC, Gilmour R. Catalytic, Vicinal Difluorination of Olefins: Creating a Hybrid, Chiral Bioisostere of the Trifluoromethyl and Ethyl Groups. ACS Catal. 2016;6: 7167-7173. Abstract
Muttach F, Rentmeister A. A Biocatalytic Cascade for Versatile One-Pot Modification of mRNA Starting from Methionine Analogues. Angew Chem Int Ed Engl 2016;55: 1917-1920. Abstract
Muttach F, Rentmeister A. One-pot modification of 5'-capped RNA based on methionine analogs. Methods 2016;107: 3-9. Abstract
Otten ABC, Theunissen TEJ, Derhaag JG, Lambrichs EH, Boesten IBW, Winandy M, van Montfoort APA, Tarbashevich K, Raz E, Gerards M, Vanoevelen JM, van den Bosch BJC, Muller M, Smeets HJM. Differences in Strength and Timing of the mtDNA Bottleneck between Zebrafish Germline and Non-germline Cells. Cell Rep 2016;16: 622-630. Abstract
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Owlarn S, Bartscherer K. Go ahead, grow a head! A planarian's guide to anterior regeneration. Regeneration (Oxf) 2016;3: 139-155. Abstract
Palei S, Mootz HD. Cyclic Peptides Made by Linking Synthetic and Genetically Encoded Fragments. Chembiochem 2016;17: 378-382. Abstract
Pohlen M, Groth C, Sauer T, Gorlich D, Mesters R, Schliemann C, Lenz G, Muller-Tidow C, Buchner T, Berdel WE, Stelljes M. Outcome of allogeneic stem cell transplantation for AML and myelodysplastic syndrome in elderly patients (60 years). Bone Marrow Transplant 2016;51: 1441-1448. Abstract
Pohlen M, Marx J, Mellmann A, Becker K, Mesters RM, Mikesch J-H, Schliemann C, Lenz G, Muller-Tidow C, Buchner T, Krug U, Stelljes M, Karch H, Peters G, Gerth HU, Gorlich D, Berdel WE. Ciprofloxacin versus colistin prophylaxis during neutropenia in acute myeloid leukemia: two parallel patient cohorts treated in a single center. Haematologica 2016;101: 1208-1215. Abstract
Rajappa R, Gauthier-Kemper A, Boning D, Huve J, Klingauf J. Synaptophysin 1 Clears Synaptobrevin 2 from the Presynaptic Active Zone to Prevent Short-Term Depression. Cell Rep 2016;14: 1369-1381. Abstract
Ramb DC, Lerchen A, Kischkewitz M, Beutel B, Fustero S, Haufe G. Addition of Nucleophiles to Fluorinated Michael Acceptors. Eur. J. Org. Chem. 2016;2016: 1751-1759. Abstract
Rao J, Pfeiffer MJ, Frank S, Adachi K, Piccini I, Quaranta R, Arauzo-Bravo M, Schwarz J, Schade D, Leidel S, Scholer HR, Seebohm G, Greber B. Stepwise Clearance of Repressive Roadblocks Drives Cardiac Induction in Human ESCs. Cell Stem Cell 2016;18: 341-353. Abstract
Rau K, Rentmeister A. CRISPR/Cas9: A New Tool for RNA Imaging in Live Cells. Chembiochem 2016;17: 1682-1684. Abstract
Redlich R, Opel N, Grotegerd D, Dohm K, Zaremba D, Burger C, Munker S, Muhlmann L, Wahl P, Heindel W, Arolt V, Alferink J, Zwanzger P, Zavorotnyy M, Kugel H, Dannlowski U. Prediction of Individual Response to Electroconvulsive Therapy via Machine Learning on Structural Magnetic Resonance Imaging Data. JAMA Psychiatry 2016;73: 557-564. Abstract
Reinhard JR, Kriz A, Galic M, Angliker N, Rajalu M, Vogt KE, Ruegg MA. The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory. Nat Commun 2016;7: 11613. Abstract
Rentmeister A, Kellermann S. Manipulation von RNA mit Designerproteinen. Nachr. Chem. 2016;64: 297-301. Abstract
Rieger S, Fischedick M, Boller K-J, Fallnich C. Suppression of resonance Raman scattering via ground state depletion towards sub-diffraction-limited label-free microscopy. Opt Express 2016;24: 20745-20754. Abstract
Riemke P, Czeh M, Fischer J, Walter C, Ghani S, Zepper M, Agelopoulos K, Lettermann S, Gebhardt ML, Mah N, Weilemann A, Grau M, Groning V, Haferlach T, Lenze D, Delwel R, Prinz M, Andrade-Navarro MA, Lenz G, Dugas M, Muller-Tidow C, Rosenbauer F. Myeloid leukemia with transdifferentiation plasticity developing from T-cell progenitors. Embo J 2016;35: 2399-2416. Abstract
Saha T, Rathmann I, Viplav A, Panzade S, Begemann I, Rasch C, Klingauf J, Matis M, Galic M. Automated analysis of filopodial length and spatially resolved protein concentration via adaptive shape tracking. Mol Biol Cell 2016;27: 3616-3626. Abstract
Santschi N, Thiehoff C, Holland MC, Daniliuc CG, Houk KN, Gilmour R. The Sulfur–Fluorine_Gauche_Effect in Coinage-Metal Complexes: Augmenting Conformational Equilibria by Complexation. Organometallics 2016;35: 3040-3044. Abstract
Sasse S, Klambt C. Repulsive Epithelial Cues Direct Glial Migration along the Nerve. Dev Cell 2016;39: 696-707. Abstract
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Grosse L, Carvalho LA, Wijkhuijs AJM, Bellingrath S, Ruland T, Ambree O, Alferink J, Ehring T, Drexhage HA, Arolt V. Clinical characteristics of inflammation-associated depression: Monocyte gene expression is age-related in major depressive disorder. Brain Behav Immun 2015;44: 48-56. Abstract
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Nielsen N, Lindemann O, Schwab A. TRP channels and STIM/ORAI proteins: sensors and effectors of cancer and stroma cell migration. Br J Pharmacol 2014;171: 5524-5540. Abstract
Prasad VP, Wagner S, Keul P, Hermann S, Levkau B, Schafers M, Haufe G. Synthesis of fluorinated analogues of sphingosine-1-phosphate antagonists as potential radiotracers for molecular imaging using positron emission tomography. Bioorg Med Chem 2014;22: 5168-5181. Abstract
Quiskamp N, Poeter M, Raabe CA, Hohenester UM, Konig S, Gerke V, Rescher U. The tumor suppressor annexin A10 is a novel component of nuclear paraspeckles. Cell Mol Life Sci 2014;71: 311-329. Abstract
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Reichman-Fried M, Raz E. Small proteins, big roles: The signaling protein Apela extends the complexity of developmental pathways in the early zebrafish embryo. Bioessays 2014;36: 741-745. Abstract
Reinhardt B, Godfrey R, Fellbrich G, Frank H, Luske A, Olieslagers S, Mertens T, Waltenberger J. Human cytomegalovirus infection impairs endothelial cell chemotaxis by disturbing VEGF signalling and actin polymerization. Cardiovasc Res 2014;104: 315-325. Abstract
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Reissner C, Stahn J, Breuer D, Klose M, Pohlentz G, Mormann M, Missler M. Dystroglycan Binding to alpha-Neurexin Competes with Neurexophilin-1 and Neuroligin in the Brain. J Biol Chem 2014;289: 27585-27603. Abstract
Rey YP, Zimmer LE, Sparr C, Tanzer EM, Schweizer WB, Senn HM, Lakhdar S, Gilmour R. Molecular Design Exploiting a Fluorine gauche Effect as a Stereoelectronic Trigger. Eur J Org Chem 2014;2014: 1202-1211. Abstract
Risse B, Otto N, Berh D, Jiang X, Klambt C. FIM imaging and FIMtrack: two new tools allowing high-throughput and cost effective locomotion analysis. J Vis Exp 2014: e52207. Abstract
Rueff A-S, Chastanet A, Dominguez-Escobar J, Yao Z, Yates J, Prejean M-V, Delumeau O, Noirot P, Wedlich-Soldner R, Filipe SR, Carballido-Lopez R. An early cytoplasmic step of peptidoglycan synthesis is associated to MreB in Bacillus subtilis. Mol Microbiol 2014;91: 348-362. Abstract
Santschi N, Gilmour R. The (not so) ephemeral trifluoromethanide anion. Angew Chem Int Ed Engl 2014;53: 11414-11415. Abstract
Schmidt R, Nippe N, Strobel K, Masthoff M, Reifschneider O, Castelli DD, Holtke C, Aime S, Karst U, Sunderkotter C, Bremer C, Faber C. Highly Shifted Proton MR Imaging: Cell Tracking by Using Direct Detection of Paramagnetic Compounds. Radiology 2014;272: 785-795. Abstract
Schulte A, Saito S, Wünsch B. Stereoselective Synthesis of_cis_,_cis_-Configured Vicinal Triamines: Stereoselective Synthesis of_cis_,_cis_-Configured Vicinal Triamines. Eur J Org Chem 2014;2014: 5749-5756. Abstract
Schulz D, Rentmeister A. Current approaches for RNA labeling in vitro and in cells based on click reactions. Chembiochem 2014;15: 2342-2347. Abstract
Schutz V, Mootz HD. Click-Tag and Amine-Tag: Chemical Tag Approaches for Efficient Protein Labeling In Vitro and on Live Cells using the Naturally Split Npu DnaE Intein. Angew Chem Int Ed Engl 2014;53: 4113-4117. Abstract
Schwab A, Stock C. Ion channels and transporters in tumour cell migration and invasion. Philos Trans R Soc Lond B Biol Sci 2014;369: 20130102. Abstract
Shah B, Puschel AW. In vivo functions of small GTPases in neocortical development. Biol Chem 2014;395: 465-476. Abstract
Thiel IV, Volkmann G, Pietrokovski S, Mootz HD. An atypical naturally split intein engineered for highly efficient protein labeling. Angew Chem Int Ed Engl 2014;53: 1306-1310. Abstract
Tiemann U, Marthaler AG, Adachi K, Wu G, Fischedick GUL, Arauzo-Bravo MJ, Scholer HR, Tapia N. Counteracting activities of OCT4 and KLF4 during reprogramming to pluripotency. Stem Cell Reports 2014;2: 351-365. Abstract
Ungru K, Tenbrinck D, Jiang X, Stypmann J. Automatic classification of left ventricular wall segments in small animal ultrasound imaging. Comput Methods Programs Biomed 2014;117: 2-12. Abstract
Vogg MC, Owlarn S, Perez Rico YA, Xie J, Suzuki Y, Gentile L, Wu W, Bartscherer K. Stem cell-dependent formation of a functional anterior regeneration pole in planarians requires Zic and Forkhead transcription factors. Dev Biol 2014;390: 136-148. Abstract
Weber F, Brune S, Korpis K, Bednarski PJ, Laurini E, Dal Col V, Pricl S, Schepmann D, Wunsch B. Synthesis, pharmacological evaluation, and sigma1 receptor interaction analysis of hydroxyethyl substituted piperazines. J Med Chem 2014;57: 2884-2894. Abstract
Wedlich-Soldner R. A longer life for yeast with good memory. Dev Cell 2014;31: 391-392. Abstract
Woerdemann M, Hörner F, Denz C. Structured attachment of bacterial molecular motors for defined micro flow induction. Optofluidics, Microfluidics, and Nanofluidics 2014;1: 19-26. Abstract
Xu C, Hasan SS, Schmidt I, Rocha SF, Pitulescu ME, Bussmann J, Meyen D, Raz E, Adams RH, Siekmann AF. Arteries are formed by vein-derived endothelial tip cells. Nat Commun 2014;5: 5758. Abstract
Xu Y, Pektor S, Balkow S, Hemkemeyer SA, Liu Z, Grobe K, Hanley PJ, Shen L, Bros M, Schmidt T, Bahler M, Grabbe S. Dendritic cell motility and T cell activation requires regulation of Rho-cofilin signaling by the Rho-GTPase activating protein myosin IXb. J Immunol 2014;192: 3559-3568. Abstract
Yang R, Kong E, Jin J, Hergovich A, Puschel AW. Rassf5 and Ndr kinases regulate neuronal polarity through Par3 phosphorylation in a novel pathway. J Cell Sci 2014;127: 3463-3476. Abstract


Abdelhady S, Kitambi SS, Lundin V, Aufschnaiter R, Sekyrova P, Sinha I, Lundgren KT, Castelo-Branco G, Linnarsson S, Wedlich-Söldner R, Teixeira A, Andäng M. Erg channel is critical in controlling cell volume during cell cycle in embryonic stem cells. PLoS One 2013;8: e72409. Abstract
Balla DZ, Gottschalk S, Shajan G, Ueberberg S, Schneider S, Hardtke-Wolenski M, Jaeckel E, Hoerr V, Faber C, Scheffler K, Pohmann R, Engelmann J. In vivo visualization of single native pancreatic islets in the mouse. Contrast Media Mol Imaging 2013;8: 495-504. Abstract
Barroso A, Woerdemann M, Vollmer A, von Bally G, Kemper B, Denz C. Three-dimensional exploration and mechano-biophysical analysis of the inner structure of living cells. Small 2013;9: 885-893. Abstract
Benning M, Brune C, Burger M, Müller J. Higher-Order TV Methods - Enhancement via Bregman Iteration. J Sci Comput 2013;54: 269-310. Abstract
Boser A, Drexler HCA, Reuter H, Schmitz H, Wu G, Scholer HR, Gentile L, Bartscherer K. SILAC proteomics of planarians identifies Ncoa5 as a conserved component of pluripotent stem cells. Cell Rep 2013;5: 1142-1155. Abstract
Brandherm I, Disse J, Zeuschner D, Gerke V. cAMP-induced secretion of endothelial von Willebrand factor is regulated by a phosphorylation/dephosphorylation switch in annexin A2. Blood 2013;122: 1042-1051. Abstract
Brune S, Pricl S, Wunsch B. Structure of the sigma1 receptor and its ligand binding site. J Med Chem 2013;56: 9809-9819. Abstract
Burger M, Dirks H, Müller J. Inverse Problems in Imaging. Rad Ser Comp App 2013;13: 135-180. Abstract
Burger M, Modersitzki J, Ruthotto L. A Hyperelastic Regularization Energy for Image Registration. SIAM J Sci Comput 2013;35: B132-B148. Abstract
Burger M, Osher S. A guide to the TV zoo. In: Burger M, Osher S. Level-Set and PDE-based Reconstruction Methods 2013;Springer: 1-70. Abstract
Burger M, Pietschmann JF, Wolfram MT. Identification of nonlinearities in transport-diffusion models of size exclusion. Inverse Probl Imag 2013;7: 1157-1182. Abstract
Cleff C, Groß P, Fallnich C, Offerhaus HL, Herek JL, Kruse K, Beeker WP, Lee CJ, Boller K-J. Stimulated-emission pumping enabling sub-diffraction-limited spatial resolution in coherent anti-Stokes Raman scattering microscopy. Phys Rev A 2013;87: 33830-33839. Abstract
Crevenna AH, Naredi-Rainer N, Schonichen A, Dzubiella J, Barber DL, Lamb DC, Wedlich-Söldner R. Electrostatics control actin filament nucleation and elongation kinetics. J Biol Chem 2013;288: 12102-12113. Abstract
Dobner S, Gross P, Fallnich C. In-line interferometric femtosecond stimulated Raman scattering spectroscopy. J Chem Phys 2013;138: 244201. Abstract
Drucker P, Pejic M, Galla H-J, Gerke V. Lipid segregation and membrane budding induced by the peripheral membrane binding protein annexin A2. J Biol Chem 2013;288: 24764-24776. Abstract
Eppelmann U, Gottardo F, Wistuba J, Ehmcke J, Kossack N, Westernstroeer B, Redmann K, Wuebbeling F, Burger M, Tuettelmann F, Kliesch S, Mallidis C. Raman microspectroscopic discrimination of TCam-2 cultures reveals the presence of two sub-populations of cells. Cell Tissue Res 2013;354: 623-632. Abstract
Foell D, Wittkowski H, Kessel C, Luken A, Weinhage T, Varga G, Vogl T, Wirth T, Viemann D, Bjork P, van Zoelen MAD, Gohar F, Srikrishna G, Kraft M, Roth J. Proinflammatory S100A12 can activate human monocytes via Toll-like receptor 4. Am J Respir Crit Care Med 2013;187: 1324-1334. Abstract
Freisinger T, Klunder B, Johnson J, Müller N, Pichler G, Beck G, Costanzo M, Boone C, Cerione RA, Frey E, Wedlich-Söldner R. Establishment of a robust single axis of cell polarity by coupling multiple positive feedback loops. Nat Commun 2013;4: 1807. Abstract
Ghavampour S, Lange C, Bottino C, Gerke V. Transcriptional profiling of human monocytes identifies the inhibitory receptor CD300a as regulator of transendothelial migration. PLoS One 2013;8: e73981. Abstract
Goudarzi M, Strate I, Paksa A, Lagendijk A-K, Bakkers J, Raz E. On the robustness of germ cell migration and microRNA-mediated regulation of chemokine signaling. Nat Genet 2013;45: 1264-1265. Abstract
Harel D, Schepmann D, Prinz H, Brun R, Schmidt TJ, Wunsch B. Natural product derived antiprotozoal agents: synthesis, biological evaluation, and structure-activity relationships of novel chromene and chromane derivatives. J Med Chem 2013;56: 7442-7448. Abstract
Holl K, Falck E, Kohler J, Schepmann D, Humpf H-U, Brust P, Wunsch B. Synthesis, characterization, and metabolism studies of fluspidine enantiomers. ChemMedChem 2013;8: 2047-2056. Abstract
Holland MC, Paul S, Schweizer WB, Bergander K, Muck-Lichtenfeld C, Lakhdar S, Mayr H, Gilmour R. Noncovalent interactions in organocatalysis: modulating conformational diversity and reactivity in the MacMillan catalyst. Angew Chem Int Ed Engl 2013;52: 7967-7971. Abstract
Hua Y, Woehler A, Kahms M, Haucke V, Neher E, Klingauf J. Blocking endocytosis enhances short-term synaptic depression under conditions of normal availability of vesicles. Neuron 2013;80: 343-349. Abstract
Jiang X, Dawood M, Gigengack F, Risse B, Schmid S, Tenbrinck D, Schäfers K. Biomedical imaging: A computer vision perspective. Lect Notes Comput Sc 2013;8047: 1-19. Abstract
Jiang X, Tenbrinck D. Region based contour detection by dynamic programming. Lect Notes Comput Sc 2013;8048: 152-159. Abstract
Junker A, Yamaguchi J, Itami K, Wunsch B. Synthesis of thiophene-based TAK-779 analogues by C-H arylation. J Org Chem 2013;78: 5579-5586. Abstract
Kemper B, Barroso A, Denz C. Combined Holographic Optical Trapping and Imaging - Exploring the Inside of Cells and Modeling Infection. Imaging Microscopy 2013;15: 41-43. Abstract
Kemper B, Barroso A, Woerdemann M, Dewenter L, Vollmer A, Schubert R, Mellmann A, von Bally G, Denz C. Towards 3D modelling and imaging of infection scenarios at the single cell level using holographic optical tweezers and digital holographic microscopy. J Biophotonics 2013;6: 260-266. Abstract
Klünder B, Freisinger T, Wedlich-Söldner R, Frey E. GDI-Mediated Cell Polarization in Yeast Provides Precise Spatial and Temporal Control of Cdc42 Signaling. PLoS Comput Biol 2013: e1003396. Abstract
Limpachayaporn P, Riemann B, Kopka K, Schober O, Schäfers M, Haufe G. Influence of 4- or 5-substituents on the pyrrolidine ring of 5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin derivatives on their inhibitory activities towards caspases-3 and -7. Eur J Med Chem 2013;64C: 562-578. Abstract
Limpachayaporn P, Schäfers M, Schober O, Kopka K, Haufe G. Synthesis of new fluorinated, 2-substituted 5-pyrrolidinylsulfonyl isatin derivatives as caspase-3 and caspase-7 inhibitors: Nonradioactive counterparts of putative PET-compatible apoptosis imaging agents. Bioorg Med Chem 2013;21: 2025-2036. Abstract
Limpachayaporn P, Wagner S, Kopka K, Hermann S, Schäfers M, Haufe G. Synthesis, 18F-radiolabeling, and in vivo biodistribution studies of N-fluorohydroxybutyl isatin sulfonamides using positron emission tomography. J Med Chem 2013;56: 4509-4520. Abstract
Lueg C, Schepmann D, Gunther R, Brust P, Wunsch B. Development of fluorinated CB(2) receptor agonists for PET studies. Bioorg Med Chem 2013;21: 7481-7498. Abstract
Marthaler AG, Tiemann U, Arauzo-Bravo MJ, Wu G, Zaehres H, Hyun JK, Han DW, Scholer HR, Tapia N. Reprogramming to pluripotency through a somatic stem cell intermediate. PLoS One 2013;8: e85138. Abstract
Marz M, Seebeck F, Bartscherer K. A Pitx transcription factor controls the establishment and maintenance of the serotonergic lineage in planarians. Development 2013;140: 4499-4509. Abstract
Paluch EK, Raz E. The role and regulation of blebs in cell migration. Curr Opin Cell Biol 2013;25: 582-590. Abstract
Paul S, Schweizer WB, Rugg G, Senn HM, Gilmour R. The fluorine-NHC gauche effect: a structural and computational study. Tetrahedron 2013;69: 5647-5659. Abstract
Petersen B, Wolf M, Austermann J, van Lent P, Föll D, Ahlmann M, Kupas V, Loser K, Sorg C, Roth J, Vogl T. The alarmin Mrp8/14 as regulator of the adaptive immune response during allergic contact dermatitis. EMBO J 2013;32: 100-111. Abstract
Retser E, Schied T, Skryabin BV, Vogl T, Kanczler JM, Hamann N, Niehoff A, Hermann S, Eisenblätter M, Wachsmuth L, Pap T, van Lent PLEM, Loser K, Roth J, Zaucke F, Ludwig S, Wixler V. Doxycycline-induced expression of transgenic human tumor necrosis factor alpha in adult mice results in psoriasis-like arthritis. Arthritis Rheum 2013;65: 2290-2300. Abstract
Rey YP, Gilmour R. Modulating NHC catalysis with fluorine. Beilstein J Org Chem 2013;9: 2812-2820. Abstract
Risse B, Thomas S, Otto N, Lopmeier T, Valkov D, Jiang X, Klambt C. FIM, a novel FTIR-based imaging method for high throughput locomotion analysis. PLoS One 2013;8: e53963. Abstract
Sander M, Squarr AJ, Risse B, Jiang X, Bogdan S. Drosophila pupal macrophages--a versatile tool for combined ex vivo and in vivo imaging of actin dynamics at high resolution. Eur J Cell Biol 2013;92: 349-354. Abstract
Sawatzky A, Tenbrinck D, Jiang X, Burger M. A Variational Framework for Region-Based Segmentation Incorporating Physical Noise Models. J Math Imaging Vision 2013;47(3): 179-209. Abstract
Schafer S, Dekiff M, Plate U, Szuwart T, Denz C, Dirksen D. Quantitative analysis of dynamic behavior of osteoblasts during in vitro formation of micro-mass cell cultures. J Biophotonics 2013;6: 637-644. Abstract
Schinor B, Wibbeling B, Haufe G. Synthesis and pKa values of 2-(3- and 4-pentafluorosulfanylphenyl)-2-fluorocyclopropylamines. J Flourine Chem 2013: 102-109. Abstract
Spoden G, Kuhling L, Cordes N, Frenzel B, Sapp M, Boller K, Florin L, Schelhaas M. Human papillomavirus types 16, 18, and 31 share similar endocytic requirements for entry. J Virol 2013;87: 7765-7773. Abstract
Tenbrinck D, Jiang X. Discriminant Analysis based Level Set Segmentation for Ultrasound Imaging. Lect Notes Comput Sc 2013;8048: 144-151. Abstract
Woerdemann M, Alpmann C, Esseling M, Denz C. Advanced optical trapping by complex beam shaping. Laser Photonics Rev 2013;7: 839–854. Abstract
Wu G, Han D, Gong Y, Sebastiano V, Gentile L, Singhal N, Adachi K, Fischedick G, Ortmeier C, Sinn M, Radstaak M, Tomilin A, Scholer HR. Establishment of totipotency does not depend on Oct4A. Nat Cell Biol 2013;15: 1089-1097. Abstract


Alpmann C, Esseling M, Rose P, Denz C. Dynamic Light Cages: Putting Absorbing Matter Behind Bars. Opt Photon News 2012;23: 48. Abstract
Claesener M, Breyholz H-J, Hermann S, Faust A, Wagner S, Schober O, Schäfers M, Kopka K. Efficient synthesis of a fluorine-18 labeled biotin derivative. Nucl Med Biol 2012;39: 1189-1194. Abstract
Dobner S, Cleff C, Fallnich C, Gross P. Interferometric background reduction for femtosecond stimulated Raman scattering loss spectroscopy. J Chem Phys 2012;137: 174201. Abstract
Hugenberg V, Haufe G. Fluoro-Pummerer rearrangement and analogous reactions. J Fluorine Chem 2012;143: 238-262. Abstract
Nazmi AR, Ozorowski G, Pejic M, Whitelegge JP, Gerke V, Luecke H. N-terminal acetylation of annexin A2 is required for S100A10 binding. Biol Chem 2012;393: 1141-1150. Abstract
Sanchez V, Redmann K, Wistuba J, Wubbeling F, Burger M, Oldenhof H, Wolkers WF, Kliesch S, Schlatt S, Mallidis C. Oxidative DNA damage in human sperm can be detected by Raman microspectroscopy. Fertil Steril 2012;98: 1124-9.e1-3. Abstract
Schrigten D, Breyholz HJ, Wagner S, Hermann S, Schober O, Schäfers M, Haufe G, Kopka K. A new generation of radiofluorinated pyrimidine-2,4,6-triones as MMP-targeted radiotracers for positron emission tomography. J Med Chem 2012: 223-232. Abstract
Tcatchoff L, Andersson S, Utskarpen A, Klokk TI, Skanland SS, Pust S, Gerke V, Sandvig K. Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin. PLoS One 2012;7: e40429. Abstract
Woerdemann M, Veiga-Gutiérrez M, De Cola L, Denz C. Creating Functional Microstructures with an Optical-Tweezers Assembly-Line. Opt Photon News 2012;23: 47. Abstract