| Baumann A, Faust A, Law MP, Kuhlmann MT, Kopka K, Schäfers M, Karst U. Metabolite identification of a radiotracer by electrochemistry coupled to liquid chromatography with mass spectrometric and radioactivity detection. Analytical Chemistry 2011;83: 5415-5421. Abstract
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| Benning M, Brune C, Burger M, Müller J. Higher-Order TV Methods - Enhancement via Bregman Iteration. J. Sci. Comp. 2011Abstract
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| Benning M, Burger M. Error Estimates for General Fidelities. Electronic Transactions on Numerical Analysis 2011;38: 44-68. Abstract
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| Boss A, Stegger L, Bisdas S, Kolb A, Schwenzer N, Pfister M, Claussen CD, Pichler BJ, Pfannenberg C. Feasibility of simultaneous PET/MR imaging in the head and upper neck area. European Radiology 2011;21: 1439-1446. Abstract
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| Di Marco GS, Reuter S, Kentrup D, Ting L, Ting L, Grabner A, Jacobi AM, Pavenstädt H, Baba HA, Tiemann K, Brand M. Cardioprotective effect of calcineurin inhibition in an animal model of renal disease. European Heart Journal 2011;32: 1935-1945. Abstract
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| Diepenbrock S, Praßni J S, Lindemann F, Bothe H W, Ropinski T. 2010 IEEE Visualization Contest Winner: Intreractive Planning for Brain Tumor Resections. IEEE Computer Graphics and Applications 2011Abstract
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| Diepenbrock S, Ropinski T , Hinrichs K H. Context-Aware Volume Navigation. IEEE Pacific Visualization Symposium (PacificVis 2011) 2011Abstract
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| Eisenblätter M, Persigehl T, Bremer C, Höltke C. Diagnostic Optical Imaging of Breast Cancer: From Animal Models to First-in-Men Studies. InTech 2011: epub. Abstract
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| Fabritz L, Herzig S. Can T-type calcium channels make a change of heart after myocardial infarction? Fiction or fact, and for better or for worse?. Cardiovascular Research 2011;91: 373-375. Abstract
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| Fabritz L, Hoogendijk MG, Scicluna BP, van Amersfoorth SCM, Fortmueller L, Wolf S, Laakmann S, Kreienkamp N, Piccini I, Breithardt G, Ruiz Noppinger P, Witt H, Ebnet K, Wichter T, Levkau B, Franke WW, Pieperhoff S, de Bakker JMT, Coronel R, Kirchhof P. Preload-reducing therapy prevents development of arrhythmogenic right ventricular cardiomyopathy in plakoglobin-deficient mice. Journal of the American College of Cardiology 2011;57: 740-750. Abstract
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| Ghanem A, Roll W, Bostani T, Dewald O, Fleischmann BK, Stypmann J, Nickenig G, Tiemann K. Cardiomyoplasty improves contractile reserve after myocardial injury in mice - functional and morphological investigations with reconstructive 3-dimensional echocardiography. Cell Transplantation 2011: epub. Abstract
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| Gigengack F, Ruthotto L, Burger M, Wolters C, Jiang X, Schäfers K. Motion Correction in Dual Gated Cardiac PET using Mass-Preserving Image Registration. IEEE Transactions on Medical Imaging 2011: epub. Abstract
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| Grabner A, Schnöckel U, Kentrup D, Schäfers M, Reuter S. Strategies for Non-Invasive Molecular Imaging of Acute Allograft Rejection by Gamma Scintigraphy and Positron Emission Tomography. Current Radiopharmaceuticals 2011;4(1): 10-23. Abstract
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| Hagerling R, Pollmann C, Kremer L, Andresen V, Kiefer F. Intravital two-photon microscopy of lymphatic vessel development and function using a transgenic Prox1 promoter-directed mOrange2 reporter mouse. Biochemical Society Transactions 2011;39: 1674-1681. Abstract
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| Herrmann S, Fabritz L, Layh B, Kirchhof P, Ludwig A. Insights into sick sinus syndrome from an inducible mouse model. Cardiovascular Research 2011;90: 38-48. Abstract
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| Huntgeburth M, Tiemann K, Shahverdyan R, Schluter K-D, Schreckenberg R, Gross M-L, Modersheim S, Caglayan E, Muller-Ehmsen J, Ghanem A, Vantler M, Zimmermann WH, Bohm M, Rosenkranz S. Transforming growth factor beta oppositely regulates the hypertrophic and contractile response to beta-adrenergic stimulation in the heart. PloS one 2011;6: e26628. Abstract
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| Kahr PC, Piccini I, Fabritz L, Greber B, Scholer H, Scheld HH, Hoffmeier A, Brown NA, Kirchhof P. Systematic analysis of gene expression differences between left and right atria in different mouse strains and in human atrial tissue. PloS one 2011;6: e26389. Abstract
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| Kentrup D, Reuter S, Schnöckel U, Grabner A, Edemir B, Pavenstadt H, Schober O, Schäfers M, Schlatter E, Bussemaker E. Hydroxyfasudil-mediated inhibition of ROCK1 and ROCK2 improves kidney function in rat renal acute ischemia-reperfusion injury. PloS one 2011;6: e26419. Abstract
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| Kies P, Paul M, Gerss J, Stegger L, Monnig G, Schober O, Wichter T, Schäfers M, Schulze-Bahr E. Impaired cardiac sympathetic innervation in symptomatic patients with long QT syndrome. European Journal of Nuclear Medicine and Molecular Imaging 2011;38: 1899-1907. Abstract
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| Kirchhof P, Kahr PC, Kaese S, Piccini I, Vokshi I, Scheld H-H, Rotering H, Fortmueller L, Laakmann S, Verheule S, Schotten U, Fabritz L, Brown NA. PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression. Circulation. Cardiovascular Genetics 2011;4: 123-133. Abstract
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| Lemoine MD, Duverger JE, Naud P, Chartier D, Qi XY, Comtois P, Fabritz L, Kirchhof P, Nattel S. Arrhythmogenic left atrial cellular electrophysiology in a murine genetic long QT syndrome model. Cardiovascular Research 2011;92: 67-74. Abstract
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| Michel K, Büther F, Law MP, Wagner S, Schober O, Hermann S, Schäfers M, Riemann B, Höltke C, Kopka K. Development and evaluation of endothelin-A receptor (radio)ligands for positron emission tomography. Journal of Medicinal Chemistry 2011;54: 939-948. Abstract
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| Paul M, Meyborg M, Boknik P, Gergs U, Schmitz W, Breithardt G, Wichter T, Neumann J. Autonomic dysfunction in patients with brugada syndrome: further biochemical evidence of altered signaling pathways. Pacing and Clinical Electrophysiology : PACE 2011;34: 1147-1153. Abstract
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| Paul M, Rahbar K, Gerss J, Kies P, Schober O, Schäfers K, Breithardt G, Schulze-Bahr E, Wichter T, Schäfers M. Microvascular dysfunction in nonfailing arrhythmogenic right ventricular cardiomyopathy. European Journal of Nuclear Medicine and Molecular Imaging 2011: epub. Abstract
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| Paul M, Stypmann J, Gerss J, Wirdeier S, Zumhagen S, Breithardt G, Schulze-Bahr E, Wichter T. Safety of endomyocardial biopsy in patients with arrhythmogenic right ventricular cardiomyopathy a study analyzing 161 diagnostic procedures. JACC. Cardiovascular Interventions 2011;4: 1142-1148. Abstract
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| Paul M, Wichter T, Kies P, Gerss J, Wollmann C, Rahbar K, Eckardt L, Breithardt G, Schober O, Schulze-Bahr E, Schäfers M. Cardiac Sympathetic Dysfunction in Genotyped Patients with Arrhythmogenic Right Ventricular Cardiomyopathy and Risk of Recurrent Ventricular Tachyarrhythmias. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2011;52: 1559-65. Abstract
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| Remmele S, Ring J, Senegas J, Heindel W, Mesters RM, Bremer C, Persigehl T. Concurrent MR blood volume and vessel size estimation in tumors by robust and simultaneous DeltaR2 and DeltaR2* quantification. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2011;66: 144-153. Abstract
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| Sawatzky A, Tenbrinck D, Jiang X, Burger M. A Variational Framework for Region-Based Segmentation Incorporating Physical Noise Models. UCLA 2011;11Abstract
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| Schmid S, Tenbrinck D, Jiang X, Schäfers K, Tiemann K, Stypmann J. Histogram-Based Optical Flow for Functional Imaging in Echocardiography. Lecture Notes in Computer Science 2011;6854/2011: 477-485. Abstract
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| von Maltzahn G, Park J-H, Lin KY, Singh N, Schwöppe C, Mesters R, Berdel WE, Ruoslahti E, Sailor MJ, Bhatia SN. Nanoparticles that communicate in vivo to amplify tumour targeting. Nature Materials 2011;10: 545-552. Abstract
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| Wagner S, Faust A, Breyholz H-J, Schober O, Schäfers M, Kopka K. The MMP inhibitor (R)-2-(N-benzyl-4-(2-[18F]fluoroethoxy)phenylsulphonamido)-N-hydroxy-3-met hylbutanamide: Improved precursor synthesis and fully automated radiosynthesis. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for use in Agriculture, Industry and Medicine 2011;69: 862-868. Abstract
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| Wenning C, Stegger D, Hermann S, Schober O, Schäfers M. F-18-FDG Imaging for Atherosclerotic Plaque Characterization. Current Cardiovascular Imaging Reports 2011;4: 190-198. Abstract
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| Büther F, Ernst I, Dawood M, Kraxner P, Schäfers M, Schober O, Schäfers KP. Detection of respiratory tumour motion using intrinsic list mode-driven gating in positron emission tomography. European Journal of Nuclear Medicine and Molecular Imaging 2010;37: 2315-2327. Abstract
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| Blana A, Kaese S, Fortmuller L, Laakmann S, Damke D, van Bragt K, Eckstein J, Piccini I, Kirchhefer U, Nattel S, Breithardt G, Carmeliet P, Carmeliet E, Schotten U, Verheule S, Kirchhof P, Fabritz L. Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability. Heart Rhythm : the Official Journal of the Heart Rhythm Society 2010;7: 1862-1869. Abstract
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| Boss A, Bisdas S, Kolb A, Hofmann M, Ernemann U, Claussen CD, Pfannenberg C, Pichler BJ, Reimold M, Stegger L. Hybrid PET/MRI of intracranial masses: initial experiences and comparison to PET/CT. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2010;51: 1198-1205. Abstract
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| Bovens S, Schulze Elfringhoff A, Kaptur M, Reinhardt D, Schäfers M, Lehr M. 1-(5-Carboxyindol-1-yl)propan-2-one Inhibitors of Human Cytosolic Phospholipase A(2)alpha: Effect of Substituents in Position 3 of the Indole Scaffold on Inhibitory Potency, Metabolic Stability, Solubility, and Bioavailability. Journal of Medicinal Chemistry 2010: epub. Abstract
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| Breyholz HJ, Wagner S, Faust A, Riemann B, Höltke C, Hermann S, Schober O, Schäfers M, Kopka K. Radiofluorinated pyrimidine-2,4,6-triones as molecular probes for noninvasive MMP-targeted imaging. ChemMedChem 2010;5: 777-789. Abstract
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| Buscher K, Judenhofer MS, Kuhlmann MT, Hermann S, Wehrl HF, Schäfers KP, Schäfers M, Pichler BJ, Stegger L. Isochronous assessment of cardiac metabolism and function in mice using hybrid PET/MRI. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2010;51: 1277-1284. Abstract
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| Dawood M, Brune C, Büther F, Jiang X, Burger M, Schober O, Schäfers M, Schäfers KP. A continuity equation based optical flow method for cardiac motion correction in 3 D PET data. Proceedings MICCA/MIA 2010;6326: 88-97. Abstract
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| Dreischaluck J, Schwöppe C, Spieker T, Kessler T, Tiemann K, Liersch R, Schliemann C, Kreuter M, Kolkmeyer A, Hintelmann H, Mesters RM, Berdel WE. Vascular infarction by subcutaneous application of tissue factor targeted to tumor vessels with NGR-peptides: activity and toxicity profile. International Journal of Oncology 2010;37: 1389-1397. Abstract
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| Drews A, Bovens S, Roebrock K, Sunderkotter C, Reinhardt D, Schäfers M, van der Velde A, Schulze Elfringhoff A, Fabian J, Lehr M. 1-(5-carboxyindol-1-yl)propan-2-one inhibitors of human cytosolic phospholipase A(2)alpha with reduced lipophilicity: synthesis, biological activity, metabolic stability, solubility, bioavailability, and topical in vivo activity. Journal of Medicinal Chemistry 2010;53: 5165-5178. Abstract
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| Fabritz L, Damke D, Emmerich M, Kaufmann SG, Theis K, Blana A, Fortmuller L, Laakmann S, Hermann S, Aleynichenko E, Steinfurt J, Volkery D, Riemann B, Kirchhefer U, Franz MR, Breithardt G, Carmeliet E, Schäfers M, Maier SKG, Carmeliet P, Kirchhof P. Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3. Cardiovascular Research 2010;87: 60-72. Abstract
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| Hugenberg V, Frohlich R, Haufe G. Oxidative desulfurization-fluorination of thioethers Application for the synthesis of fluorinated nitrogen containing building blocks. Organic & Biomolecular Chemistry 2010;8: 5682-5691. Abstract
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| Hugenberg V, Wagner S, Kopka K, Schober O, Schäfers M, Haufe G. Synthesis of geminal difluorides by oxidative desulfurization-difluorination of alkyl aryl thioethers with halonium electrophiles in the presence of fluorinating reagents and its application for 18F-radiolabeling. The Journal of Organic Chemistry 2010;75: 6086-6095. Abstract
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| Larmann J, Frenzel T, Hahnenkamp A, Herzog C, Lorenz A, Steinbicker AU, Calmer S, Harendza T, Schmitz M, Echtermeyer F, Hildebrand R, Bremer C, Theilmeier G. In vivo fluorescence-mediated tomography for quantification of urokinase receptor-dependent leukocyte trafficking in inflammation. Anesthesiology 2010;113: 610-618. Abstract
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| Law MP, Schäfers K, Kopka K, Wagner S, Schober O, Schäfers M. Molecular imaging of cardiac sympathetic innervation by 11C-mHED and PET: from man to mouse?. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2010;51: 1269-1276. Abstract
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| Law MP, Wagner S, Kopka K, Renner C, Pike VW, Schober O, Schäfers M. Preclinical evaluation of an 18F-labelled beta1-adrenoceptor selective radioligand based on ICI 89,406. Nuclear Medicine and Biology 2010;37: 517-526. Abstract
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| Lindemann F, Ropinski T. Advanced Light Material Interaction for Direct Volume Rendering. IEEE/EG International Symposium on Volume Graphics 2010: 101-108.
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| Meß C, Ropinski T. Efficient Acquisition and Clustering of Local Histograms for Representing Voxel Neighborhoods. IEEE/EG International Symposium on Volume Graphics 2010: 117-124.
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| Mensmann J, Ropinski T, Hinrichs K H. An Advanced Volume Raycasting Technique using GPU Stream Processing. GRAPP: International Conference on Computer Graphics Theory and Applications 2010: 190-198.
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| Mensmann J, Ropinski T, Hinrichs K H. A GPU-Supported Lossless Compression Scheme for Rendering Time-Varying Volume Data. IEEE/EG International Symposium on Volume Graphics 2010: 109-116.
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| Praßni J, S, Ropinski T, Mensmann J, Hinrichs K H. Shape-based Transfer Functions for Volume Visualization. IEEE Pacific Visualization Symposium (PacificVis 2010) 2010: 9-16.
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| Prassni J-S, Ropinski T, Hinrichs K. Uncertainty-aware guided volume segmentation. IEEE Transactions on Visualization and Computer Graphics 2010;16: 1358-1365. Abstract
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| Reuter S, Schnöckel U, Edemir B, Schröter R, Kentrup D, Pavenstädt H, Schober O, Schlatter E, Gabriels G, Schäfers M. Potential of noninvasive serial assessment of acute renal allograft rejection by 18F-FDG PET to monitor treatment efficiency. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2010;51: 1644-1652. Abstract
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| Ropinski T, Döring C, Rezk-Salama C. Interactive Volumetric Lighting Simulating Scattering and Shadowing. IEEE Pacific Visualization Symposium (PacificVis 2010) 2010: 169-176.
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| Ropinski T, Döring C, Rezk-Salama C. Advanced Volume Illumination with Unconstrained Light Source Positioning. IEEE Computer Graphics and Applications 2010Abstract
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| Schäfers M, Schober O, Hermann S. Matrix-metalloproteinases as imaging targets for inflammatory activity in atherosclerotic plaques. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2010;51: 663-666. Abstract
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| Schnöckel U, Hermann S, Stegger L, Law M, Kuhlmann M, Schober O, Schäfers K, Schäfers M. Small-animal PET: a promising, non-invasive tool in pre-clinical research. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2010;74: 50-54. Abstract
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| Schwöppe C, Kessler T, Persigehl T, Liersch R, Hintelmann H, Dreischaluck J, Ring J, Bremer C, Heindel W, Mesters RM, Berdel WE. Tissue-factor fusion proteins induce occlusion of tumor vessels. Thrombosis Research 2010;125 Suppl 2: S143-50. Abstract
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| Tsotsalas MM, Kopka K, Luppi G, Wagner S, Law MP, Schäfers M, De Cola L. Encapsulating (111)In in nanocontainers for scintigraphic imaging: synthesis, characterization, and in vivo biodistribution. ACS nano 2010;4: 342-348. Abstract
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| Büther F, Dawood M, Stegger L, Wübbeling F, Schäfers M, Schober O, Schäfers KP. List mode-driven cardiac and respiratory gating in PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50: 674-681. Abstract
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| Benning M, Burger M. Error estimation for variational models with non-Gaussian noise. Technical Report 2009Abstract
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| Bunck AC, Engelen MA, Schnackenburg B, Furkert J, Bremer C, Heindel W, Stypmann J, Maintz D. Feasibility of functional cardiac MR imaging in mice using a clinical 3 Tesla whole body scanner. Investigative Radiology 2009;44: 749-756. Abstract
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| Faust A, Hermann S, Wagner S, Haufe G, Schober O, Schäfers M, Kopka K. Molecular imaging of apoptosis in vivo with scintigraphic and optical biomarkers--a status report. Anti-Cancer Agents in Medicinal Chemistry 2009;9: 968-985. Abstract
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| Ghanema A, Steingen C, Brenig F, Funcke F, Bai ZY, Hall C, Chin CT, Nickenig G, Bloch W, Tiemann K. Focused ultrasound-induced stimulation of microbubbles augments site-targeted engraftment of mesenchymal stem cells after acute myocardial infarction. Journal of Molecular and Cellular Cardiology 2009;47: 411-418. Abstract
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| Höltke C, Faust A, Breyholz H-J, Kopka K, Schober O, Riemann B, Bremer C, Schäfers M, Wagner S. Non-invasive approaches to visualize the endothelin axis in vivo using state-of-the-art molecular imaging modalities. Mini Reviews in Medicinal Chemistry 2009;9: 1580-1595. Abstract
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| Höltke C, Law MP, Wagner S, Kopka K, Faust A, Breyholz H-J, Schober O, Bremer C, Riemann B, Schäfers M. PET-compatible endothelin receptor radioligands: synthesis and first in vitro and in vivo studies. Bioorganic & Medicinal Chemistry 2009;17: 7197-7208. Abstract
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| Höltke C, Waldeck J, Kopka K, Heindel W, Schober O, Schäfers M, Bremer C. Biodistribution of a nonpeptidic fluorescent endothelin A receptor imaging probe. Molecular Imaging : Official Journal of the Society for Molecular Imaging 2009;8: 27-34. Abstract
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| Hugenberg V, Haufe G. Oxidative Desulfurization-Difluorination of Alkyl Aryl Thioethers: Synthesis of ω-Substituted 1,1-Difluoroalkanes. Synlett 2009: 106-108. Abstract
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| Kato K, Schober O, Ikeda M, Schäfers M, Ishigaki T, Kies P, Naganawa S, Stegger L. Evaluation and comparison of 11C-choline uptake and calcification in aortic and common carotid arterial walls with combined PET/CT. European Journal of Nuclear Medicine and Molecular Imaging 2009;36: 1622-1628. Abstract
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| Meyer-Spradow J, Ropinski T, Mensmann J, Hinrichs K H. A Rapid-Prototyping Environment for Ray-Casting-Based Volume Visualizations. IEEE Computer Graphics and Applications (Applications Department) 2009: 6-13. Abstract
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| Podichetty AK, Faust A, Kopka K, Wagner S, Schober O, Schäfers M, Haufe G. Fluorinated isatin derivatives Part 1: synthesis of new N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatins as potent caspase-3 and -7 inhibitors. Bioorganic & Medicinal Chemistry 2009;17: 2680-2688. Abstract
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| Podichetty AK, Wagner S, Schroer S, Faust A, Schäfers M, Schober O, Kopka K, Haufe G. Fluorinated isatin derivatives Part 2 New N-substituted 5-pyrrolidinylsulfonyl isatins as potential tools for molecular imaging of caspases in apoptosis. Journal of medicinal chemistry 2009;52: 3484-3495. Abstract
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| Praßni J S, Ropinski T, Hinrichs K H. Efficient Boundary Detection and Transfer Function Generation in Direct Volume Rendering. Proceedings of the 14th International Fall Workshop on Vision, Modeling, and Visualization (VMV09) 2009: 285-294.
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| Range FT, Paul M, Schäfers KP, Acil T, Kies P, Hermann S, Schober O, Breithardt G, Wichter T, Schäfers MA. Myocardial perfusion in nonischemic dilated cardiomyopathy with and without atrial fibrillation. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2009;50: 390-396. Abstract
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| Reuter S, Bangen P, Edemir B, Hillebrand U, Pavenstädt H, Heidenreich S, Lang D. The HSP72 stress response of monocytes from patients on haemodialysis is impaired. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association 2009;24: 2838-2846. Abstract
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| Reuter S, Schnöckel U, Schroter R, Schober O, Pavenstädt H, Schäfers M, Gabriels G, Schlatter E. Non-invasive imaging of acute renal allograft rejection in rats using small animal F-FDG-PET. PloS one 2009;4: e5296. Abstract
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| Ropinski T, Hermann S, Reich R, Schäfers M, Hinrichs K. Multimodal vessel visualization of mouse aorta PET/CT scans. IEEE Transactions on Visualization and Computer Graphics 2009;15: 1515-1522. Abstract
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| Ropinski T, Viola I, Biermann M, Hauser H, Hinrichs K. Multimodal Visualization with Interactive Closeups. IEEE Pacific Visualization 2009
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| Sawatzky A, Brune C, Müller J, Burger M. Total Variation Processing of Images with Poisson Statistics. Proceedings of the 13th International Conference on Computer Analysis of Images and Patterns 2009;5702: 533-540. Abstract
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| Stegger L, Heijman E, Schäfers KP, Nicolay K, Schäfers MA, Strijkers GJ. Quantification of left ventricular volumes and ejection fraction in mice using PET, compared with MRI. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2009;50: 132-138. Abstract
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| Wagner S, Breyholz H-J, Höltke C, Faust A, Schober O, Schäfers M, Kopka K. A new 18F-labelled derivative of the MMP inhibitor CGS 27023A for PET: radiosynthesis and initial small-animal PET studies. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for use in Agriculture, Industry and Medicine 2009;67: 606-610. Abstract
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| Waldeyer C, Fabritz L, Fortmueller L, Gerss J, Damke D, Blana A, Laakmann S, Kreienkamp N, Volkery D, Breithardt G, Kirchhof P. Regional, age-dependent, and genotype-dependent differences in ventricular action potential duration and activation time in 410 Langendorff-perfused mouse hearts. Basic Research in Cardiology 2009;104: 523-533. Abstract
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| Benning M, Kösters M, Wübbeling F, Schäfers K, Burger M. A nonlinear variational method for improved quantification of myocardial blood flow using dynamic H215O pET. IEEE 2008: 4472-4477.
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| Faust A, Waschkau B, Waldeck J, Höltke C, Breyholz H-J, Wagner S, Kopka K, Heindel W, Schäfers M, Bremer C. Synthesis and evaluation of a novel fluorescent photoprobe for imaging matrix metalloproteinases. Bioconjugate Chemistry 2008;19: 1001-1008. Abstract
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| Ghanem A, Troatz C, Elhafi N, Dewald O, Heeschen C, Nickenig G, Stypmann J, Tiemann K. Quantitation of myocardial borderzone using reconstructive 3-D echocardiography after chronic infarction in rats: incremental value of low-dose dobutamine. Ultrasound in Medicine & Biology 2008;34: 559-566. Abstract
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| Grote-Wessels S, Baba HA, Boknik P, El-Armouche A, Fabritz L, Gillmann H-J, Kucerova D, Matus M, Muller FU, Neumann J, Schmitz M, Stumpel F, Theilmeier G, Wohlschlaeger J, Schmitz W, Kirchhefer U. Inhibition of protein phosphatase 1 by inhibitor-2 exacerbates progression of cardiac failure in a model with pressure overload. Cardiovascular Research 2008;79: 464-471. Abstract
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| Hoefler T, Schellmann M, Gorlatch S, Lumsdaine A. Communication Optimization for Medical Image Reconstruction Algorithms. Springer-Verlag 2008;5205: 75-83.
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| Kopka K, Schober O, Wagner S. (18)F-labelled cardiac PET tracers: selected probes for the molecular imaging of transporters, receptors and proteases. Basic Research in Cardiology 2008;103: 131-143. Abstract
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| Law MP, Wagner S, Kopka K, Pike VW, Schober O, Schäfers M. Are [O-methyl-11C]derivatives of ICI 89,406 beta1-adrenoceptor selective radioligands suitable for PET?. European Journal of Nuclear Medicine and Molecular Imaging 2008;35: 174-185. Abstract
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| Levkau B, Schäfers M, Wohlschlaeger J, von Wnuck Lipinski K, Keul P, Hermann S, Kawaguchi N, Kirchhof P, Fabritz L, Stypmann J, Stegger L, Flogel U, Schrader J, Fischer JW, Hsieh P, Ou YL, Mehrhof F, Tiemann K, Ghanem A, Matus M, Neumann J, Heusch G, Schmid KW, Conway EM, Baba HA. Survivin determines cardiac function by controlling total cardiomyocyte number. Circulation 2008;117: 1583-1593. Abstract
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| Makita N, Behr E, Shimizu W, Horie M, Sunami A, Crotti L, Schulze-Bahr E, Fukuhara S, Mochizuki N, Makiyama T, Itoh H, Christiansen M, McKeown P, Miyamoto K, Kamakura S, Tsutsui H, Schwartz PJ, George ALJ, Roden DM. The E1784K mutation in SCN5A is associated with mixed clinical phenotype of type 3 long QT syndrome. The Journal of Clinical Investigation 2008;118: 2219-2229. Abstract
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| Mensmann J, Ropinski T, Hinrichs K. Accelerating Volume Raycasting using Occlusion Frustums. IEEE/EG 2008: 147-154.
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| Mensmann J, Ropinski T, Hinrichs K. Interactive Cutting Operations for Generating Anatomical Illustrations from Volumetric Data Sets. J WSCG 2008: 89-96.
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| Meyer-Spradow J, Stegger L, Doring C, Ropinski T, Hinrichs K. Glyph-based SPECT visualization for the diagnosis of coronary artery disease. IEEE Transactions on Visualization and Computer Graphics 2008;14: 1499-1506. Abstract
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| Riemann B, Schäfers KP, Schober O, Schäfers M. Small animal PET in preclinical studies: opportunities and challenges. The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutica 2008;52: 215-221.
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| Ropinski T, Kasten J, Hinrichs K. Efficient Shadows for GPU-based Volume Raycasting. WSCG 2008: 17-24.
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| Ropinski T, Meyer-Spradow J, Diepenbrock S, Mensmann J, Hinrichs K. Interactive Volume Rendering with Dynamic Ambient Occlusion and Color Bleeding. J Computer Graphics Forum 2008: 567-576.
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| Ropinski T, Petkov B, Fabritz B, Hinrichs K. Interactive Reconstruction and Visualization of Dynamic 3D Ultrasound Data Sets. GRAPP 2008: 308-315.
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| Ropinski T, Praßni J S, Steinicke F, Hinrichs K H. Stroke-Based Transfer Function Design. IEEE/EG International Symposium on Volume and Point-Based Graphics 2008: 41-48.
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| Schäfers KP, Stegger L. Combined imaging of molecular function and morphology with PET/CT and SPECT/CT: image fusion and motion correction. Basic Research in Cardiology 2008;103: 191-199. Abstract
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| Schellmann M, Vording J, Gorlatch S. Systematic Parallelization of Medical Image Reconstruction for Graphics Hardware. Springer-Verlag 2008;5168: 811-821.
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| Schellmann M, Vording J, Gorlatch S, Meilander D. Cost-effective medical image reconstruction: from clusters to graphics processing units. ACM 2008: 283-292.
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| Stelljes M, Hermann S, Albring J, Kohler G, Loffler M, Franzius C, Poremba C, Schlosser C, Volkmann S, Opitz C, Bremer C, Kucharzik T, Silling G, Schober O, Berdel WE, Schäfers M, Kienast J. Clinical molecular imaging in intestinal graft-versus-host disease: mapping of disease activity, prediction, and monitoring of treatment efficiency by positron emission tomography. Blood 2008;111: 2909-2918. Abstract
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| Tsotsalas M, Busby M, Gianolio E, Aime S, De Cola L. Functionalized nanocontainers as dual magnetic and optical probes for molecular imaging applications. Chemistry of Materials 2008;20: 5888-5893.
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| von Wallbrunn A, Waldeck J, Höltke C, Zuhlsdorf M, Mesters R, Heindel W, Schäfers M, Bremer C. In vivo optical imaging of CD13/APN-expression in tumor xenografts. Journal of Biomedical Optics 2008;13: 011007. Abstract
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| Waldeck J, Hager F, Höltke C, Lanckohr C, von Wallbrunn A, Torsello G, Heindel W, Theilmeier G, Schäfers M, Bremer C. Fluorescence reflectance imaging of macrophage-rich atherosclerotic plaques using an alphavbeta3 integrin-targeted fluorochrome. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2008;49: 1845-1851. Abstract
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| Wall A, Persigehl T, Hauff P, Licha K, Schirner M, Muller S, von Wallbrunn A, Matuszewski L, Heindel W, Bremer C. Differentiation of angiogenic burden in human cancer xenografts using a perfusion-type optical contrast agent (SIDAG). Breast Cancer Research : BCR 2008;10: R23. Abstract
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| Breyholz HJ, Wagner S, Levkau B, Schober O, Schäfers M, Kopka K. A 18F-radiolabeled analogue of CGS 27023A as a potential agent for assessment of matrix-metalloproteinase activity in vivo. The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutica 2007;51: 24-32. Abstract
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| Dawood M, Büther F, Lang N, Schober O, Schäfers KP. Respiratory gating in positron emission tomography: a quantitative comparison of different gating schemes. Medical Physics 2007;34: 3067-3076. Abstract
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| Dawood M, Fieseler M, Büther F, Jiang X, Schäfers KP. A Multi-resolution Optical Flow Based Approach to Respiratory Motion Correction in 3D PET/CT Images. Lecture Notes in Computer Science 2007: 314-322. Abstract
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| Faust A, Wagner S, Law MP, Hermann S, Schnöckel U, Keul P, Schober O, Schäfers M, Levkau B, Kopka K. The nonpeptidyl caspase binding radioligand (S)-1-(4-(2-[18F]Fluoroethoxy)-benzyl)-5-[1-(2-methoxymethylpyrrolidinyl)s ulfonyl]isatin ([18F]CbR) as potential positron emission tomography-compatible apoptosis imaging agent. The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutica 2007;51: 67-73. Abstract
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| Hartung D, Schäfers M, Fujimoto S, Levkau B, Narula N, Kopka K, Virmani R, Reutelingsperger C, Hofstra L, Kolodgie F D, Petrov A, Narula J. Targeting of matrix metalloproteinase activation for noninvasive detection of vulnerable atherosclerotic lesions. European Journal of Nuclear Medicine and Molecular Imaging 2007;34: 1-8.
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| Höltke C, von Wallbrunn A, Kopka K, Schober O, Heindel W, Schäfers M, Bremer C. A fluorescent photoprobe for the imaging of endothelin receptors. Bioconjugate Chemistry 2007;18: 685-694. Abstract
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| Höltke C, Wagner S, Breyholz H J, Faust A, Law M P, Schäfers M, Kopka K. Developement, synthesis and in vitro evaluation of novel et-a receptor pet-radioligands based on pd 156707. J Labelled Comp Radiopharm. 2007;50: 258.
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| Keul P, Tolle M, Lucke S, von Wnuck Lipinski K, Heusch G, Schuchardt M, van der Giet M, Levkau B. The sphingosine-1-phosphate analogue FTY720 reduces atherosclerosis in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology 2007;27: 607-613. Abstract
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| Kirchhof P, Klimas J, Fabritz L, Zwiener M, Jones LR, Schäfers M, Hermann S, Boknik P, Schmitz W, Breithardt G, Kirchhefer U, Neumann J. Stress and high heart rate provoke ventricular tachycardia in mice expressing triadin. Journal of Molecular and Cellular Cardiology 2007;42: 962-971. Abstract
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| Kopka K, Breyholz H J, Wagner S, Brandau W, Hermann S, Schober O, Levkau B, Bremcer C, Schäfers M. Radioiodinated pyrimidine-2,4,6-triones as model probes for the in vivo molecular imaging of activated mmps. J Labelled Comp Radiopharm. 2007;50: 310.
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| Lang N, Hermann S, Hold S, Mienkina M, Stegger L, Stypmann J, Schober O, Schäfers M, Schäfers KP, Schmitz G. Hybrid 3D Sono/PET in a mouse. European Journal of Nuclear Medicine and Molecular Imaging 2007;34: 1706-1707. Abstract
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| Meyer-Spradow J, Ropinski T, Hinrichs K. Supporting Depth and Motion Perception in Medical Volume Data. Mathematics+Visualization 2007: 121-133.
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| Popovic Z, Otter M, Calzaferri G, De Cola L. Self-assembling living systems with functional nanomaterials. Angewandte Chemie (International ed.in English) 2007;46: 6188-6191.
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| Ropinski T, Praßni J S, Roters J, Hinrichs K. Internal Labels as Shape Cues for Medical Illustration. VMV 2007: 203-212.
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| Ropinski T, Specht M, Meyer-Spradow J, Hinrichs K, Preim B. Surface Glyphs for Visualizing Multimodal Volume Data. VMV 2007: 3-12.
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| Schellmann M, Bohm D, Wichmann S, Gorlatch S. Towards a grid system for medical image reconstruction. IEEE 2007: 3019-3025.
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| Schellmann M, Gorlatch S. Comparison of Two Decomposition Strategies for Parallelizing the 3D List-Mode OSEM Algorithm. Proceedings Fully 3D Meeting and HPIR Workshop 2007: 37-40.
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| Stegger L, Lipke CSA, Kies P, Nowak B, Schober O, Buell U, Schäfers M, Schaefer WM. Quantification of left ventricular volumes and ejection fraction from gated 99mTc-MIBI SPECT: validation of an elastic surface model approach in comparison to cardiac magnetic resonance imaging, 4D-MSPECT and QGS. European Journal of Nuclear Medicine and Molecular Imaging 2007;34: 900-909. Abstract
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| Stegger L, Schäfers K, Kopka K, Wagner S, Hermann S, Kies P, Law M, Schober O, Schäfers M. Molecular cardiovascular imaging using scintigraphic methods. European Radiology 2007;17: 1422-1432. Abstract
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| Stypmann J. Doppler ultrasound in mice. Echocardiography (Mount Kisco, N.Y.) 2007;24: 97-112. Abstract
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| Stypmann J, Engelen MA, Orwat S, Bilbilis K, Rothenburger M, Eckardt L, Haverkamp W, Horst J, Dworniczak B, Pennekamp P. Cardiovascular characterization of Pkd2(+/LacZ) mice, an animal model for the autosomal dominant polycystic kidney disease type 2 (ADPKD2). International Journal of Cardiology 2007;120: 158-166. Abstract
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| von Wallbrunn A, Höltke C, Zuhlsdorf M, Heindel W, Schäfers M, Bremer C. In vivo imaging of integrin alpha v beta 3 expression using fluorescence-mediated tomography. European Journal of Nuclear Medicine and Molecular Imaging 2007;34: 745-754. Abstract
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| Wagner S, Breyholz H-J, Law MP, Faust A, Höltke C, Schroer S, Haufe G, Levkau B, Schober O, Schäfers M, Kopka K. Novel fluorinated derivatives of the broad-spectrum MMP inhibitors N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](benzyl)- and (3-picolyl)-amino]-3-methyl-butanamide as potential tools for the molecular imaging of activated MMPs with PET. Journal of Medicinal Chemistry 2007;50: 5752-5764. Abstract
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| Walter DH, Rochwalsky U, Reinhold J, Seeger F, Aicher A, Urbich C, Spyridopoulos I, Chun J, Brinkmann V, Keul P, Levkau B, Zeiher AM, Dimmeler S, Haendeler J. Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor. Arteriosclerosis, Thrombosis, and Vascular Biology 2007;27: 275-282. Abstract
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| Dawood M, Büther F, Lang N, Jiang X, Schäfers KP. Transforming Static CT in Gated PET/CT Studies to Multiple Respiratory Phases. International Conference on Pattern Recognition 2006: 1026-1029. Abstract
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| Kirchhof P, Fabritz L, Zwiener M, Witt H, Schäfers M, Zellerhoff S, Paul M, Athai T, Hiller K-H, Baba HA, Breithardt G, Ruiz P, Wichter T, Levkau B. Age- and training-dependent development of arrhythmogenic right ventricular cardiomyopathy in heterozygous plakoglobin-deficient mice. Circulation 2006;114: 1799-1806. Abstract
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| Kopka K, Faust A, Keul P, Wagner S, Breyholz H-J, Höltke C, Schober O, Schäfers M, Levkau B. 5-pyrrolidinylsulfonyl isatins as a potential tool for the molecular imaging of caspases in apoptosis. Journal of Medicinal Chemistry 2006;49: 6704-6715. Abstract
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| Meyer-Spradow J, Ropinski T, Vahrenhold J, Hinrichs K. Illustrating Dynamics of Time-Varying Volume Datasets in Static Images. VMV 2006: 333-340.
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| Ropinski T, Meyer-Spradow J, Steinicke F, Hinrichs K H. Design of a User-Oriented Application for the Exploration of Medical Datasets. Springer E\&I Journal, Special Edition on New Computing in Medical Informatics \& Health Care 2006: 131-134. Abstract
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| Ropinski T, Steinicke F, Hinrichs K. Visually Supporting Depth Perception in Angiography Imaging. Smart Graphics 2006: 93-104.
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| Schäfers KP, Lang N, Stegger L, Schober O, Schäfers M. Gated listmode acquisition with the quadHIDAC animal PET to image mouse hearts. Zeitschrift fur Medizinische Physik 2006;16: 60-66. Abstract
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| Schellmann M, Kösters T, Gorlatch S. Parallelization and Runtime Prediction of the ListMode OSEM Algorithm for 3D PET Reconstruction. IEEE 2006: 2190-2195.
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| Stegger L, Hoffmeier A-N, Schäfers KP, Hermann S, Schober O, Schäfers MA, Theilmeier G. Accurate noninvasive measurement of infarct size in mice with high-resolution PET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2006;47: 1837-1844. Abstract
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| Stypmann J, Janssen PML, Prestle J, Engelen MA, Kogler H, Lullmann-Rauch R, Eckardt L, von Figura K, Landgrebe J, Mleczko A, Saftig P. LAMP-2 deficient mice show depressed cardiac contractile function without significant changes in calcium handling. Basic Research in Cardiology 2006;101: 281-291. Abstract
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| Theilmeier G, Schmidt C, Herrmann J, Keul P, Schäfers M, Herrgott I, Mersmann J, Larmann J, Hermann S, Stypmann J, Schober O, Hildebrand R, Schulz R, Heusch G, Haude M, von Wnuck Lipinski K, Herzog C, Schmitz M, Erbel R, Chun J, Levkau B. High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor. Circulation 2006;114: 1403-1409. Abstract
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| Wagner S, Dybkova N, Rasenack ECL, Jacobshagen C, Fabritz L, Kirchhof P, Maier SKG, Zhang T, Hasenfuss G, Brown JH, Bers DM, Maier LS. Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels. The Journal of Clinical Investigation 2006;116: 3127-3138. Abstract
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| Wagner S, Law MP, Riemann B, Pike VW, Breyholz HJ, Höltke C, Faust A, Renner C, Schober O, Schäfers M, Kopka K. Synthesis of an F-18-labelled high affinity beta(1)-adrenoceptor PET radioligand based on ICI 89,406. J Labelled Comp Radiopharm. 2006;49: 177-195.
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