Carina Bodden


Institute of Neuro- and Behavioural Biology
Department of Behavioural Biology
Badestraße 13
D-48149 Münster

Phone: +49 (0) 251/83 23842
Fax.: +49 (0) 251/83 23896
E-mail: carina.bodden@uni-muenster.de
Website
Carina-bodden-h205-2

Joined OCC in 2014

Research Project

Traditionally, the accumulation of adversity over the lifetime is seen as a major risk factor for psychiatric disease. However, more recently, an alternative view has been proposed, which suggests individuals to be at highest risk for developing pathologies in case that the early programming environment differs from the later environment (“mismatch hypothesis”).
This project aims to elucidate the effects of life history on emotional behavior, hormone levels, and epigenetic modifications in adulthood and how this process is modulated by the activity of the serotonergic system. For this purpose, mice lacking the serotonin transporter (5-HTT) totally or in part - an established mouse model of increased anxiety-like behavior - will be compared with wildtype controls. (SFB/TRR 58 “Fear, Anxiety, Anxiety Disorders”).

PhD Committee

Prof. Dr. Norbert Sachser (Department of Behavioural Biology, University of Münster)
Prof. Dr. Klaus-Peter Lesch (Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Würzburg)
Prof. Dr. Hans-Christian Pape (Institute of Physiology I, University of Münster)

Publications

Remmes, J; Bodden, C; Richter, SH; Lesting, J; Sachser, N; Pape, HC, Seidenbecher, T (2016): Impact of Life History on Fear Memory and Extinction. Frontiers in Behavioral Neuroscience 10: 185. doi:10.3389/fnbeh.2016.00185

Bodden, C; Richter, SH; Schreiber, RS; Kloke, V; Gerss, J; Palme, R; Lesch, KP; Lewejohann, L; Kaiser, S; Sacher, N (2015): Benefits of adversity?! How life history affects the behavioral profile of mice varying in serotonin transporter genotype. Frontiers in Behavioral Neuroscience 9: 47. doi:10.3389/fnbeh.2015.00047

Kloke, V.; Schreiber, R.S.; Bodden, C.; Moellers, J.; Ruhmann, H.; Kaiser, S.; Lesch, K.-P.; Sacher, N.; Lewejohann, L. (2014). Hope for the best or prepare for the worst? Towards a spatial cognitive bias test for mice. PLoS ONE 9(8): e105431. doi:10.1371/journal.pone.0105431

Heiming, R.S.; Bodden, C.; Jansen, F.; Lewejohann, L.; Kaiser, S.; Lesch, K.-P.; Palme, R.; Sachser, N. (2011). Living in a dangerous world decreases maternal care: a study in serotonin transporter knockout mice. Hormones and Behavior: 397-407. doi:10.1016/j.yhbeh.2011.07.006

Conference Contributions

Bodden, C.; Richter, S.H.; Schreiber, R.; Kloke, V.; Gerß, J.; Palme, R.; Lesch, K.-P.; Lewejohann, L.; Kaiser, S.; Sachser, N. (2016). Benefits of adversity?! How life history affects the behavioral profile of mice. Poster presentation at the 8th European Conference on Behavioural Biology, Vienna, Austria.

Bodden, C.; Richter, S.H.; Schreiber, R.; Kloke, V.; Gerß, J.; Palme, R.; Lesch, K.-P.; Lewejohann, L.; Kaiser, S.; Sachser, N. (2016). Benefits of adversity?! How life history affects the behavioral profile of mice varying in serotonin transporter genotype. Poster presentation at the 10th FENS Forum of Neuroscience, Copenhagen, Denmark.

Bodden, C. (2015). Benefits of adversity?! How life history affects the behavioral profile of mice varying in serotonin transporter genotype. Oral presentation at the 4th International Symposium of the SFB / TRR 58 Fear, Anxiety, Anxiety Disorders, Münster, Germany.

Bodden, C.; Richter, S.H.; Schreiber, R.; Kloke, V.; Gerß, J.; Palme, R.; Lesch, K.-P.; Lewejohann, L.; Kaiser, S.; Sachser, N. (2015). Benefits of Adversity?! The Impact of Life History and Serotonin Transporter Genotype on the Behavioral Profile of Mice. Poster presentation at the 10th Topical meeting of the Ethological Society, Hamburg, Germany.

Bodden, C.; Heiming, R.S.; Kloke, V.; Richter, S.H.; Palme, R.; Lesch, K.-P.; Lewejohann, L.; Kaiser, S.; Sachser, N. (2014). Benefits of Adversity? The Impact of Life History and Serotonin Transporter Genotype on the Behavioral Profile of Mice. Poster presentation at the 7th European Conference on Behavioral Biology, Prague, Czech Republic.

Bodden, C.; Kaiser, S.; Sachser, N. (2014). Consequences of life history and serotonin transporter genotype on behavioral profiles of mice. Oral presentation at the 9th Topical meeting of the Ethological Society, Tutzing, Germany.

Heiming, R.S.; Bodden, C.; Jansen, F.; Lewejohann, L.; Kaiser, S.; Lesch, K.-P.; Palme, R.; Sachser, N. (2013). Living in a dangerous world decreases maternal care: A study in serotonin transporter knockout mice. Poster presentation at the 11th Graduate Student Meeting of the Graduate Student Meeting of the German Zoological Society and the Ethological Society, Münster, Germany

Heiming, R.S.; Bodden, C.; Jansen, F.; Lewejohann, L.; Kaiser, S.; Lesch, K.-P.; Palme, R.; Sachser, N. (2012). Living in a dangerous world decreases maternal care: A study in serotonin transporter knockout mice. Poster presentation at the 6th European Conference on Behavioural Biology, Essen, Germany.

CV

*1986 Kleve, Germany
2007-2013 Studies in Biology at the University of Münster
2010 Bachelor thesis, Department of Behavioural Biology, University of Münster. Title: “Simulation of a dangerous environment during gestation and lactation: Effects on stress hormones and maternal behavior in heterozygous serotonin transporter knockout mice” (Supervisor Prof. Dr. N. Sachser)
2011 External studies at the Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Würzburg
2013 Master thesis, Department of Behavioural Biology, University of Münster. Title: “Match or mismatch: consequences of different life histories on the anxiety-like behavior of male serotonin transporter knockout mice” (Supervisor Prof. Dr. N. Sachser)
2013 Beginning of PhD research project, Department of Behavioural Biology, University of Münster
2015 Research stay at the Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Würzburg