Research Areas

Alzheimer's disease: effects of environmental enrichment

Selected Publications

Herring A, Lewejohann L, Donath A, Sachser N, Paulus W, Keyvani K. Preventive and therapeutic environmental enrichment counteract A beta pathology by different molecular mechanisms. Acta Neuropathol (Berl). 2009;118(3):444-444

Lewejohann L, Reefmann N, Widmann P, Ambrée O, Herring A, Keyvani K, Paulus W, Sachser N. Transgenic Alzheimer mice in a semi-naturalistic environment: more plaques, yet not compromised in daily life. Behav Brain Res. 2009;201(1):99-102

Herring A, Ambrée O, Tomm M, Habermann H, Sachser N, Paulus W, Keyvani K. Environmental enrichment enhances cellular plasticity in transgenic mice with Alzheimer-like pathology. Exp Neurol. 2009;216(1):184-92

Ambrée O, Richter H, Sachser N, Lewejohann L, Dere E, de Souza Silva MA, Herring A, Keyvani K, Paulus W, Schäbitz WR. Levodopa ameliorates learning and memory deficits in a murine model of Alzheimer's disease. Neurobiol Aging. 2009;30(8):1192-204

Herring A, Ambree O, Tomm M, Habermann H, Sachser N, Paulus W, Keyvani K. Environmental enrichment enhances cellular plasticity in mice with Alzheimer-like pathology. Acta Neuropathol (Berl). 2008;116(3):23 -

Richter H, Ambrée O, Lewejohann L, Herring A, Keyvani K, Paulus W, Palme R, Touma C, Schäbitz WR, Sachser N. Wheel-running in a transgenic mouse model of Alzheimer's disease: protection or symptom? Behav Brain Res. 2008;190(1):74-84

Academic CV

1985 MD, University of Erlangen (Neurophysiology)
1986-1989 Postdoctoral Fellow, Institute of Brain Research, University of Tübingen, Germany
1989-1990 Research Associate, Ludwig Boltzmann Institute of Clinical Neurobiology, Vienna, Austria
1990-1994 Assistant Professor, Institute of Pathology, University of Würzburg, Germany
1994 Habilitation and venia legendi in Neuropathology, Medical Faculty, University of Würzburg
1994-1995 Research Fellow, Molecular Neurogenetics Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
1995-1996 Senior Registrar, Institute of Neuropathology, University Hospital, Zurich, Switzerland
1996-1998 Professor of Neuropathology and Head of Department of Neuropathology, University of Erlangen, Germany
since 1998 Professor of Neuropathology and Head of Institute of Neuropathology, University Hospital, Münster, Germany

Honours and Special Recognitions

Parkinson Prize, German Association of Neurology
Rubinstein Award, American Association of Neuropathologists
Editor-in-Chief, Acta Neuropathologica