I aim to understand neurobiological mechanisms that are fundamental to naturally occurring sleep, attention, or the conscious awareness of our environment. The same state-regulating mechanisms can also be the cause for epilepsy, schizophrenia, or autism spectrum disorders. Understanding these mechanisms is a crucial step to understanding the complex organization of our brain and to the treatment of these diseases.
- Kohmann D, Lüttjohann A, Seidenbecher T, Coulon P*, Pape HC (2016): Short term depression of gap junctional coupling in reticular thalamic neurons of absence epileptic rats. J Physiol. doi: 10.1113/JP271811. [Epub ahead of print], *equally contributing senior author.
- Coulon P, Herr D, Kanyshkova T, Meuth P, Budde T, and Pape HC (2009): Burst discharges in neurons of the thalamic reticular nucleus are shaped by calcium-induced calcium release. Cell Calcium, 46, 333-346.
- Coulon P, Kanyshkova T, Broicher T, Munsch T, Wettschureck N, Seidenbecher T, Meuth SG, Offermanns S, Pape HC, and Budde T (2010): Activity modes in thalamocortical relay neurons are modulated by Gq/G11 family G-proteins. Front Cell Neurosci, 4:132.
- Greber B, Coulon P, Zhang M, Moritz S, Frank S, Müller Molina AJ, Araúzo-Bravo MJ, Han DW, Pape HC, and Schöler HR (2011): FGF signaling inhibits neural induction in human embryonic stem cells. EMBO J, 30(24), 4874-4884.
- Coulon P, Budde T, and Pape HC (2012): The sleep relay - the role of the thalamus in central and de-central sleep regulation. Pflügers Arch, 463(1), 53-71.
- Gerard E, Hochstrate P, Dierkes PW, and Coulon P (2012): Functional properties and cell type specific distribution of Ih channels in leech neurons. J Exp Biol, 215(2), 227-238. IF 2012: 3.236.
- Born G, Breuer D, Wang S, Rohlmann A, Coulon P, Vakili P, Kiefer F, Heine M, Pape HC, and Missler M (2014): Modulation of Synaptic Function through the α−Neurexin-specific Ligand Neurexophilin-1. PNAS, 111(13), E1274-83.
- Cerina M, Skudlarek H, *Coulon P, Meuth P, Kanyshkova T, Nguyen XV, Göbel K, Seidenbecher T, Meuth SG, Pape HC, Budde T (2015): Thalamic Kv7 channels: pharmacological properties and activity control during noxious signal processing. Br J Pharmacol, 172(12), 3126-40.
|since 2015||Seattle Children’s Research Institute, Center for Integrated Brain Research, Seattle, WA, USA|
|2014-2015||Institute of Anatomy and Molecular Neurobiology and Epilepsy Research Center, Münster, Germany|
|since 2013||Privatdozent (Assistant Professor), University Münster, Germany, Venia legendi in Physiology|
|2012-2014||Principal Investigator, Innovative Medical Research (IMF), Münster, Germany|
Postdoc and Senior Postdoc, Institute of Physiology I (Neurophysiology), University Münster, Germany
|2005-2006||Coordinator of the International Graduate School of Neuroscience (IGSN), University Bochum, Germany|
|2001-2005||Research associate and PhD student, Institute of Neurobiology, Heinrich-Heine-University Düsseldorf, Germany, “Dr. rer. nat.” (PhD) and “Dipl. Biol.” (MSc), Majors: Neurobiology, Biophysics, Parasitology, Physics|
Honours and Special Recognitions
- Editorial Board Member, European Journal of Physiology, Pflügers Archiv (since 2013)
- Member of the Scientific Advisory Board of the “Razavi International Journal of Medicine” (since 2013)
- Pilot project: “Ca2+ -induced Ca2+-release in neurons of the thalamic reticular nucleus“, Innovative Medical Research (IMF), Münster, Germany, (CO210803)
- Full project: “The role of electrical synapses in an epilepsy model: Ca2+-induced reciprocations between neurons of the thalamic reticular nucleus”, Innovative Medizinische Forschung (IMF) Münster, Germany, (CO121008)
- Award #1 for an outstanding poster, 87th meeting of the German Physiological Society, Cologne 2008
- Travel grant to the 2009 meeting of the Society for Neuroscience in Chicago from the Friends of Epilepsy Research at the University of Münster
- Appointed examiner in Physiology for the Medical Licensure Act (2008 – 2014)