Research Areas

I aim to understand neurobiological mechanisms that are fundamental to naturally occurring sleep, attention, or the conscious awareness of our environment. The same state-regulating mechanisms can also be the cause for epilepsy, schizophrenia, or autism spectrum disorders. Understanding these mechanisms is a crucial step to understanding the complex organization of our brain and to the treatment of these diseases.

Selected Publications

  1. Kohmann D, Lüttjohann A, Seidenbecher T, Coulon P*, Pape HC (2016): Short term depression of gap junctional coupling in reticular thalamic neurons of absence epileptic rats. J Physiol. doi: 10.1113/JP271811. [Epub ahead of print], *equally contributing senior author.
  2. Coulon P, Herr D, Kanyshkova T, Meuth P, Budde T, and Pape HC (2009): Burst discharges in neurons of the thalamic reticular nucleus are shaped by calcium-induced calcium release. Cell Calcium, 46, 333-346.
  3. Coulon P, Kanyshkova T, Broicher T, Munsch T, Wettschureck N, Seidenbecher T, Meuth SG, Offermanns S, Pape HC, and Budde T (2010): Activity modes in thalamocortical relay neurons are modulated by Gq/G11 family G-proteins. Front Cell Neurosci, 4:132.
  4. Greber B, Coulon P, Zhang M, Moritz S, Frank S, Müller Molina AJ, Araúzo-Bravo MJ, Han DW, Pape HC, and Schöler HR (2011): FGF signaling inhibits neural induction in human embryonic stem cells. EMBO J, 30(24), 4874-4884.
  5. Coulon P, Budde T, and Pape HC (2012): The sleep relay - the role of the thalamus in central and de-central sleep regulation. Pflügers Arch, 463(1), 53-71.
  6. Gerard E, Hochstrate P, Dierkes PW, and Coulon P (2012): Functional properties and cell type specific distribution of Ih channels in leech neurons. J Exp Biol, 215(2), 227-238. IF 2012: 3.236.
  7. Born G, Breuer D, Wang S, Rohlmann A, Coulon P, Vakili P, Kiefer F, Heine M, Pape HC, and Missler M (2014): Modulation of Synaptic Function through the α−Neurexin-specific Ligand Neurexophilin-1. PNAS, 111(13), E1274-83.
  8. Cerina M, Skudlarek H, *Coulon P, Meuth P, Kanyshkova T, Nguyen XV, Göbel K, Seidenbecher T, Meuth SG, Pape HC, Budde T (2015): Thalamic Kv7 channels: pharmacological properties and activity control during noxious signal processing. Br J Pharmacol, 172(12), 3126-40.

Academic CV

since 2015 Seattle Children’s Research Institute, Center for Integrated Brain Research, Seattle, WA, USA
2014-2015 Institute of Anatomy and Molecular Neurobiology and Epilepsy Research Center, Münster, Germany
since 2013 Privatdozent (Assistant Professor), University Münster, Germany, Venia legendi in Physiology
2012-2014 Principal Investigator, Innovative Medical Research (IMF), Münster, Germany
Postdoc and Senior Postdoc, Institute of Physiology I (Neurophysiology), University Münster, Germany
2005-2006 Coordinator of the International Graduate School of Neuro­science (IGSN), University Bochum, Germany
2001-2005 Research associate and PhD student, Institute of Neurobiology, Heinrich-Heine-University Düsseldorf, Germany, “Dr. rer. nat.” (PhD) and “Dipl. Biol.” (MSc), Majors: Neurobiology, Biophysics, Parasitology, Physics

Honours and Special Recognitions

  1. Editorial Board Member, European Journal of Physiology, Pflügers Archiv (since 2013)
  2. Member of the Scientific Advisory Board of the “Razavi International Journal of Medicine” (since 2013)
  3. Pilot project: “Ca2+ -induced Ca2+-release in neurons of the thalamic reticular nucleus“, Innovative Medical Research (IMF), Münster, Germany, (CO210803)
  4. Full project: “The role of electrical synapses in an epilepsy model: Ca2+-induced reciprocations between neurons of the thalamic reticular nucleus”, Innovative Medizinische Forschung (IMF) Münster, Germany, (CO121008)
  5. Award #1 for an outstanding poster, 87th meeting of the German Physiological Society, Cologne 2008
  6. Travel grant to the 2009 meeting of the Society for Neuroscience in Chicago from the Friends of Epilepsy Research at the University of Münster
  7. Appointed examiner in Physiology for the Medical Licensure Act (2008 – 2014)