PD Dr. Carsten Wolters


University of Münster
Institute for Biomagnetism and Biosignalanalysis (IBB)
Malmedyweg 15
D-48149 Münster

Phone: +49/(0)251-83-56904
Fax: +49/(0)251-83-56874
Email: carsten.wolters@uni-muenster.de
Website with detailed CV and publication and research files
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Short CV

Carsten H. Wolters received the diploma degree in Mathematics with a minor in Medicine from the RWTH Aachen, Aachen, Germany, the Ph.D. degree in Mathematics from the University of Leipzig, Leipzig, Germany and the Habilitation in Mathematics from the University of Münster, Münster, Germany, in 1997, 2003 and 2008, respectively. From 1997 to 2004, he was with the Max Planck Institutes for Human Cognitive and Brain Sciences and Mathematics in the Sciences, Leipzig, Germany. From 01/2004 to 02/2005, he joined the Scientific Computing and Imaging Institute at the University of Utah, Salt Lake City, USA. Since 03/2005, he is a Research Associate with the Institute for Biomagnetism and Biosignalanalysis (IBB) at the University of Münster, Münster, Germany. Since 11/2008, he is heading the research group ”Methods in Bioelectromagnetism” at the IBB.

Research Areas

The main research areas of the research group ”Methods in Bioelectromagnetism” at the IBB are the development of new methods and applications for multimodal brain imaging and brain stimulation to reconstruct and manipulate neuronal networks in the brain. Brain imaging methods include modalities such as Electroencephalography (EEG), Magnetoencephalography (MEG), Magnetic Resonance Imaging (MRI), diffusion MRI (dMRI), functional MRI (fMRI) and Positron Emmission Tomography (PET). A special focus is on the development of multimodal imaging and combined EEG/MEG/MRI source reconstruction methods using new forward (mainly finite element method based) and inverse approaches (Bayesian estimation, Kalman-filtering, spatio-temporal current density approaches, beamforming, dipole fitting and scanning techniques). In the brain stimulation research field we contribute new optimization methods for multi-sensor setups to transcranial direct and alternating current stimulation (tDCS, tACS), transcranial magnetic stimulation (TMS) and combined tCS/TMS. We develop artifact-correction, linear and non-linear registration as well as segmentation approaches for structural MRI such as T1-MRI, T2-MRI and dMRI and for PET. The new methodology is applied in the field of neuroscientific brain research and in clinical applications such as presurgical epilepsy diagnosis and schizophrenia.

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Selected Publications

Aydin, Ü., Vorwerk, J., Dümpelmann, M., Küpper, P., Kugel, H., Heers, M., Wellmer, J., Kellinghaus, C., Haueisen, J., Rampp, S., Stefan, H. and Wolters, C.H., Combined EEG/MEG Can Outperform Single Modality EEG or MEG Source Reconstruction in Presurgical Epilepsy Diagnosis, PLoS ONE, 10(3): e0118753. (2015). DOI: 10.1371/journal.pone.0118753, PubMed

Lucka, F., Pursiainen, S., Burger, M. and Wolters, C.H., Hierarchical Bayesian Inference for the EEG Inverse Problem using Realistic FE Head Models: Depth Localization and Source Separation for Focal Primary Currents, NeuroImage, 61(4), pp.1364--1382, (2012). DOI: 10.1016/j.neuroimage.2012.04.017, PubMed

Ruthotto, L., Kugel, H., Olesch, J., Fischer, B., Modersitzki, J., Burger, M., and Wolters, C.H., Diffeomorphic susceptibility artifact correction of diffusion-weighted magnetic resonance images, Phys.Med.Biol., 57(18), pp.5715-5731, (2012). DOI: 10.1088/0031-9155/57/18/5715

Schmidt, C., Wagner, S., Burger, M., van Rienen, U. and Wolters, C.H., Impact of Uncertain Head Tissue Conductivity in the Optimization of Transcranial Direct Current Stimulation for an Auditory Target, J. Neural Eng., 12(4):046028 (11pp), (2015). DOI: 10.1088/1741-2560/12/4/046028, PubMed

Wolters, C.H., Köstler, H., Möller, C., Härdtlein, J., Grasedyck, L., Hackbusch, W., Numerical mathematics of the subtraction approach for the modeling of a current dipole in EEG source reconstruction using finite element head models. SIAM J. on Scientific Computing, Vol. 30, No. 1, pp. 24-45 (2007). DOI: 10.1137/060659053

Book Chapter

de Munck, J.C., Wolters, C. H., Clerc, M. "EEG & MEG forward modeling". In R.Brette & A.Destexhe (eds.): Handbook of Neural Activity Measurement, Cambridge University Press, New York, ISBN 978-0-521-51622-8, (2012). DOI: 10.1017/CBO9780511979958, Chapter DOI: 10.1017/CBO9780511979958.006

Honours and Special Recognitions

01/2015 Journal of Neural Engineering: Selected as one of the 16 highlights of 2014 (http://iopscience.iop.org/1741-2552/page/Highlights-of-2014): Wagner S, Rampersad SM, Aydin Ü, Vorwerk J, Oostendorp TF, Neuling T, Herrmann CS, Stegeman DF, Wolters CH, Investigation of tDCS volume conduction effects in a highly realistic head model, J. Neural Eng., 11:016002(14pp), (2014).
04/2014 Lucka, F., Tellen, S., Wolters, C.H., Burger, M., Award for the second best poster presentation, Workshop "Innovative Verarbeitung bioelektrischer und biomagnetischer Signale" - bbs2014, Physikalisch-Technische Bundesanstalt, Berlin, Germany, April 10-11 (2014). http://www.bbs2014.ptb.de/bbs2014/bbs2014-home.html
11/2013 Wagner S., Aydin Ü., Vorwerk J., Herrmann, C., Burger M., Wolters C.H., Award for the best poster presentation, NeuroVisionen 9, 29.11.2013, Cologne.
11/2012 Faculty of 1000, 20.Nov.2012; F1000 Prime Recommendation of: Neuling, T., Rach, S., Wagner, S., Wolters, C.H. and Herrmann, C.S., NeuroImage, 63(2):771-778, (2012). DOI: 10.3410/f.717962715.793464678
10/2012 Lucka, F., Pursiainen, S., Burger, M. and Wolters, C.H., Award for the best poster presentation, NeuroVisionen 8, 26.10.2012, Aachen, http://www.neuro-zentrum.rwth-aachen.de/neurovisionen8.html
04/2012 Lucka, F., Pursiainen, S., Burger, M. and Wolters, C.H., Award for the best scientific contribution to the section "biomagnetism", Workshop "Innovative Verarbeitung bioelektrischer und biomagnetischer Signale" - bbs2012, Physikalisch-Technische Bundesanstalt, 19.-20.04.2012, Berlin, http://www.bbs2012.ptb.de/bbs2012/bbs2012.html
03/2012 Ruthotto, L., Gigengack, F., Burger, M., Wolters, C.H., Jiang, X., Schaefers, K.P. and Modersitzki, J., Award for the best scientific contribution to the conference "Bildverarbeitung für die Medizin", Berlin, March 18-20, http://www.bvm-workshop.org, http://www.mic.uni-luebeck.de/nc/news/newsdetails/article/lars-ruthotto-won-bvm-award-2012.html
05/2010 First Muenster Science Slam (Lars Ruthotto) http://www.youtube.com/watch?v=h2Sbw6b11q8
11/2007 Paper evaluated for Faculty of 1000 Biology: Wolters, C.H., Anwander, A., Tricoche, X., Weinstein, D., Koch, M.A., and MacLeod, R.S., NeuroImage, 30(3):813-826(2006). http://www.f1000biology.com/article/id/1030531/evaluation
08/2002 Anwander, A., Wolters, C.H., Dümpelmann, M. and Knösche, T.R. Young Investigators Award, 13th Int.Conf. on Biomagnetism, Jena.
06/1998 Wolters, C.H., Friedrich Springorum medal, RWTH Aachen.
1992 Wolters, C.H., DAAD-grant for INSA de Lyon (http://www.insa-lyon.fr), 1992-1993, Lyon, France.