Professor Dr. Uwe Karst
Professur für Analytische Chemie (Prof. Karst)
Corrensstr. 28/30
Research Areas
- Hyphenated techniques
- Nanoparticles
- Speciation Analysis
- Applied Atomic Spectroscopy
Further Affiliation at the University of Münster
CV
Education
- Habilitation in Analytical Chemistry (Univ. of Muenster)
- Dr. rer. nat. (Univ. of Muenster, K. Cammann)
- Undergraduate studies of chemistry at the Westfälische-Wilhelms Universität Muenster
Positions
- Chair of Analytical Chemistry (Univ. of Muenster, Muenster)
- Chair of Analytical Chemistry (Univ. of Twente, Enschede)
- Independent research
- Postdoctoral researcher (Univ. of Colorado, Boulder, R.E. Sievers)
- Research associate (Univ. of North Carolina, Chapel Hill, R.M. Wightman)
Honors
- 2. Place at the 5th Nordic Conference on Plasma Spectrochemistry Poster Award Session 2010 – Royal Society of Chemistry
- 1. Place at the 5th Nordic Conference on Plasma Spectrochemistry Poster Award Session 2010 – Royal Society of Chemistry
- Fresenius-Preis – Gesellschaft Deutscher Chemiker (GDCh)
- 4th Nordic Conference on Plasma Spectrochemistry Poster Award 2008 – Norwegian Chemical Society - Division of Analytical Sciences
- Fachgruppenpreis der Fachgruppe Analytische Chemie – FG Analytische Chemie in der Gesellschaft Deutscher Chemiker (GDCh)
External Functions
- Elected member of the DFG Fachkollegium "Analytical Chemistry, Method Development"
- German Chemical Society (GDCh)
- German Society for Mass Spectrometry (DGMS)
- American Chemical Society (ACS)
Projects
In Process
- BACCARA – International Graduate School of Battery Chemistry, Characterization, Analysis, Recycling and Application ( – )
Individual Granted Project: Federal Ministry of Culture and Science of the Federal State of North Rhine-Westphalia - CRC 1450 B02 - Quantitative MRI of organ-specific vascular permeability and immune cell dynamics by combination with mass spectrometric imaging ( – )
Subproject in DFG-Joint Project Hosted at the University of Münster: DFG - Collaborative Research Centre | Project Number: SFB 1450/1, B02
Finished
- NanoBioQuant – NanoBioQuant - Quantifizierung von Nanomaterialien im Gewebe für die regulatorische Analytik und Entwicklung vin In-vitro-Methoden ( – )
participations in bmbf-joint project: Federal Ministry of Education and Research | Project Number: 03XP0213D - Multiscale Green Biology Münster - from molecule to ecosystem: Green knowledge for education, research and society in times of climate change ( – )
Internally at the University of Münster Funded Project: Uni Münster-internal funding - Topical Programs - EXC 1003 B1 - Formation and Properties of Epithelial and Endothelial Barriers ( – )
Subproject in DFG-Joint Project Hosted at the University of Münster: DFG - Cluster of Excellence | Project Number: EXC1003/1 - EXC 1003 A5 - Surface-Targeted Tracking of Individual Cells In Vivo ( – )
Subproject in DFG-Joint Project Hosted at the University of Münster: DFG - Cluster of Excellence | Project Number: EXC1003/1 - EU-NCL – European Nanomedicine Characterization Laboratory ( – )
participations in other joint project: French Alternative Energies and Atomic Energy Commission | Project Number: 654190 - LC/electrochemistry/mass spectrometry in (bio)analytical chemistry, drug metabolism and proteomics ( – )
Individual Granted Project: DFG - Individual Grants Programme | Project Number: KA 1093/7-2 - Laserablations-ICP-MS-Untersuchungen an Gewebecryoschnitten und MALDI/MS-Untersuchungen von Gewebecryoschnitten ( – )
Individual Granted Project: Bayer Schering Pharma AG - Artificial Kidney - Safety analysis and optimization of electrochemical dialysate regeneration ( – )
Individual Granted Project: Dutch Kidney Foundation - NanoBioDetect – NanoBioDetect - Nanopartikel im Gewebe: Detektion, Quantifizierung und Darstellung biologischer Effektmarker ( – )
participations in bmbf-joint project: Federal Ministry of Education and Research | Project Number: 03X0146E - Studie zur Interaktion von biologischem Gewebe und Metallen ( – )
Individual Granted Project: German Academic Exchange Service | Project Number: 57219660 - Development of analytical methods for the evaluation of gadolinium species after in-vivo administration ( – )
Individual Granted Project: Guerbet SA - Aerosols and Imaging mass spectrometry ( – )
Individual Granted Project: DFG - Initiation of International Collaboration | Project Number: KA 1093/12-1 - EXC 1003 FF-2013-17 - Studying Cells in Motion by Complementary Magnetic Resonance and Mass Spectrometric Imaging ( – )
Subproject in DFG-Joint Project Hosted at the University of Münster: DFG - Cluster of Excellence - Fluoreszenzbasierte Analytik zur Sicherung von Warenketten ( – )
participations in bmbf-joint project: Federal Ministry of Education and Research | Project Number: 13N12012 - Investigation of the oxidative profile of chemicals by electrochemistry coupled to mass spectrometry ( – )
Individual Granted Project: Wirtschaft | Project Number: CH-2010-0836 - Molecules and Materials – NRW Research School "Molecules and Materials – A Common Design Principle" ( – )
Individual Granted Project: Federal Ministry of Culture and Science of the Federal State of North Rhine-Westphalia - FLEET - Flottenversuch Elektromobilität ( – )
participations in other joint project: Federal Ministry of Economic Affairs and Climate Action | Project Number: 0325071E - Third International Symposium on Metallomics, 15.-18.06.2011 ( – )
Scientific Event: DFG - International Scientific Events | Project Number: KA 1093/10
- BACCARA – International Graduate School of Battery Chemistry, Characterization, Analysis, Recycling and Application ( – )
Publications
- (). Superparamagnetic Nanoparticles with Phosphorescent Complexes as Hybrid Contrast Agents: Integration of MRI and PLIM. SMALL SCIENCE, 2024. doi: 10.1002/smsc.202300145.
- . (). Contiguous Silver(I)-Mediated Base Pairs of Imidazophenanthroline and Canonical Nucleobases in DNA Duplexes: Formation of Classical Duplexes versus Homodimer Formation. Bioconjugate Chemistry, 35, 99–106. doi: 10.1021/acs.bioconjchem.3c00494.
- . (). Analysis of the elemental species-dependent uptake of lanthanide complexes in Arabidopsis thaliana plants by LA-ICP-MS. Chemosphere, 338, 139534–139534. doi: 10.1016/j.chemosphere.2023.139534.
- . (). High-Voltage Instability of Vinylene Carbonate (VC): Impact of Formed Poly-VC on Interphases and Toxicity. Advanced Science, 11(1), Article 2305282. doi: 10.1002/advs.202305282.
- . (). Chiral-at-Metal Silver-Mediated Base Pairs: Metal-Centred Chirality versus DNA Helical Chirality. Chemistry - A European Journal, 29, Article e202202630. doi: 10.1002/chem.202202630.
- . (). Development of an electrochemical flow-through cell for the fast and easy generation of isotopically labeled metabolite standards. Drug Testing and Analysis, 14(2), 262–268. doi: 10.1002/dta.3175.
- . (). Combined speciation analysis and elemental bioimaging provide new insight into gadolinium retention in kidney. Metallomics, 14(3), mfac004. doi: 10.1093/mtomcs/mfac004.
- . (). A simple preparation protocol for shipping and storage of tissue sections for laser ablation-inductively coupled plasma-mass spectrometry imaging. Metallomics, 14(3), mfac013. doi: 10.1093/mtomcs/mfac013.
- . (). Quantitative elemental bioimaging: an antibody-based double-labelling method to quantify the cell-specific distribution of silver nanoparticles in lung tissue sections. Journal of Analytical Atomic Spectrometry, 37, 1084–1089. doi: 10.1039/d1ja00466b.
- . (). Fingerprints of Element Concentrations in Infective Endocarditis Obtained by Mass Spectrometric Imaging and t-Distributed Stochastic Neighbor Embedding. ACS Infectious Diseases, 8(2), 360–372. doi: 10.1021/acsinfecdis.1c00485.
- . (). Elemental bioimaging of Zn and Cd in leaves of hyperaccumulator Arabidopsis halleri using laser ablation-inductively coupled plasma-mass spectrometry and referencing strategies. Chemosphere, 305, Article 135267. doi: 10.1016/j.chemosphere.2022.135267.
- . (). Species-dependent interaction of Gd-based contrast agents with humic substances. Chemosphere, 300, Article 134528. doi: 10.1016/j.chemosphere.2022.134528.
- . (). Gadolinium retention in the tunica media of arterial walls—a complementary study using elemental bioimaging and immunogold staining. Metallomics, 14(6), Article mfac029. doi: 10.1093/mtomcs/mfac029.
- . (). Tattoo Pigment Identification in Inks and Skin Biopsies of Adverse Reactions by Complementary Elemental and Molecular Bioimaging with Mass Spectral Library Matching. Analytical Chemistry, 94(8), 3581–3589. doi: 10.1021/acs.analchem.1c04922.
- . (). LA-ICP-MS and Immunohistochemical Staining with Lanthanide-Labeled Antibodies to Study the Uptake of CeO2 Nanoparticles by Macrophages in Tissue Sections. Chemical Research in Toxicology, 35(6), 981–991. doi: 10.1021/acs.chemrestox.1c00433.
- . (). Long-term Gadolinium Retention in the Healthy Rat Brain: Comparison between Gadopiclenol, Gadobutrol, and Gadodiamide. Radiology, 305(1), 179–189. doi: 10.1148/radiol.212600.
- . (). A model to visualize the fate of iron after intracranial hemorrhage using isotopic tracers and elemental bioimaging. Metallomics, 14(8), Article mfac057. doi: 10.1093/mtomcs/mfac057.
- . (). Iron Oxide Nanoparticles for Visualization of Prostate Cancer in MRI. Cancers, 14(12), Article 2909. doi: 10.3390/cancers14122909.
- (). Multiparametric MRI enables for differentiation of different degrees of malignancy in two murine models of breast cancer. Frontiers in Oncology, 12, Article 1000036. doi: 10.3389/fonc.2022.1000036.
- . (). A fast and automated separation and quantification method for bromine speciation analyzing bromide and 5-bromo-2’-deoxyuridine in enzymatically digested DNA samples via IC-ICP-MS. Journal of Chromatography A, 1652, 462370. doi: 10.1016/j.chroma.2021.462370.
- . (). Deposition patterns of iatrogenic lanthanum and gadolinium in the human body depend on delivered chemical binding forms. Journal of Trace Elements in Medicine and Biology, 63(126665). doi: 10.1016/j.jtemb.2020.126665.
- . (). Visualization and Quantification of the Extracellular Matrix in Prostate Cancer Using an Elastin Specific Molecular Probe. Biology -Basel, 10(11), 1217. doi: 10.3390/biology10111217.
- . (). Gadolinium Tissue Distribution in a Large-Animal Model after a Single Dose of Gadolinium-based Contrast Agents. Radiology, 301(3), 637–642. doi: 10.1148/radiol.2021210553.
- . (). Weighted Linear Regression Improves Accuracy of Quantitative Elemental Bioimaging by Means of LA-ICP-MS. Analytical Chemistry, 93(47), 15720–15727. doi: 10.1021/acs.analchem.1c03630.
- . (). Fast and Automated Monitoringh of Gadolinium-based Contrast Agents in Surface Waters. Water Research, 207(117836). doi: 10.1016/j.watres.2021.117836.
- . (). Automated Chiral Analysis of Amino Acids Based on Chiral Derivatization and Trapped Ion Mobility-Mass Spectrometry. Analytical Chemistry, 93(2), 878–885. doi: 10.1021/acs.analchem.0c03481.
- . (). Determination of metal uptake in single organisms, Corophium volutator, via complementary electrothermal vaporization/inductively coupled plasma mass spectrometry and laser ablation/inductively coupled plasma mass spectrometry. Rapid Communications in Mass Spectrometry, 35(2). doi: 10.1002/rcm.8953. [online first]
- . (). Complementing Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry Imaging with Chromatography Data for Improved Assignment of Isobaric and Isomeric Phospholipids Utilizing Trapped Ion Mobility-Mass Spectrometry. Analytical Chemistry, 93(4), 2135–2143. doi: 10.1021/acs.analchem.0c03942.
- . (). Elastin-specific MRI of extracellular matrix-remodelling following hepatic radiofrequency-ablation in a VX2 liver tumor model. Scientific Reports, 11(1). doi: 10.1038/s41598-021-86417-6.
- (). Determination of gadolinium MRI contrast agents in fresh and oceanic waters of Australia employing micro-solid phase extraction, HILIC-ICP-MS and bandpass mass filtering. Journal of Analytical Atomic Spectrometry, 36(4), 767–775.
- (). Effect of Doxycycline on Survival in Abdominal Aortic Aneurysms in a Mouse Model. Contrast Media and Molecular Imaging, 2021. doi: 10.1155/2021/9999847.
- (). Noninvasive imaging of vascular permeability to predict the risk of rupture in abdominal aortic aneurysms using an albumin-binding probe (vol 10, 3231. Scientific Reports, 11(1). doi: 10.1038/s41598-021-89153-z.
- (). Simultaneous molecular MRI of extracellular matrix collagen and inflammatory activity to predict abdominal aortic aneurysm rupture (vol 10, 15206, 2020). Scientific Reports, 11(1). doi: 10.1038/s41598-021-89154-y.
- (). Spatially and size-resolved analysis of gold nanoparticles in rat spleen after intratracheal instillation by laser ablation-inductively coupled plasma-mass spectrometry. Metallomics, 13(6). doi: 10.1093/mtomcs/mfab028.
- (). Ion identity molecular networking for mass spectrometry-based metabolomics in the GNPS environment. Nature Communications, 12(1). doi: 10.1038/s41467-021-23953-9.
- (). Use of C. elegans as a 3R-compliant in vivo model for the chemoprevention of cisplatin-induced neurotoxicity. Experimental Neurology, 341(113705). doi: 10.1016/j.expneurol.2021.113705.
- (). Microscale Parallel Synthesis of Acylated Aminotriazoles Enabling the Development of Factor XIIa and Thrombin Inhibitors. ChemMedChem, 16(24), 3672–3690. doi: 10.1002/cmdc.202100431.
- (). Mild Dissolution/Recomplexation Strategy for Speciation Analysis of Gadolinium from MR Contrast Agents in Bone Tissues by Means of HPLC-ICP-MS. Analytical Chemistry, 93(33), 11398–11405. doi: 10.1021/acs.analchem.1c01100.
- (). Plug-and-play laser ablation-mass spectrometry for molecular imaging by means of dielectric barrier discharge ionization. Analytica Chimica Acta, 1177. doi: 10.1016/j.aca.2021.338770.
- (). Microfluidic Electrochemistry Meets Trapped Ion Mobility Spectrometry and High-Resolution Mass Spectrometry-In Situ Generation, Separation, and Detection of Isomeric Conjugates of Paracetamol and Ethoxyquin. Analytical Chemistry, 93(37), 12740–12747. doi: 10.1021/acs.analchem.1c02791.
- (). Simulation of the oxidative metabolization pattern of netupitant, an NK1 receptor antagonist, by electrochemistry coupled to mass spectrometry. Journal of Pharmaceutical Analysis, 11(5), 661–666. doi: 10.1016/j.jpha.2021.03.011.
- (). Development of an electrochemical flow-through cell for the fast and easy generation of isotopically labeled metabolite standards. Drug Testing and Analysis, 14(2), 262-268. doi: 10.1002/dta.3175. [online first]
- (). Towards precise arterial input functions derived from dynamic contrast-enhanced MRI through a novel extracorporeal circulation approach in mice. Magnetic Resonance in Medicine, 2020, 1404–1415. doi: 10.1002/mrm.28214.
- . (). Identification and Differentiation of Commercial and Military Explosives via High Performance Liquid Chromatography – High Resolution Mass Spectrometry (HPLC-HRMS), X-Ray Diffractometry (XRD) and X-Ray Fluorescence spectroscopy (XRF): Towards a Forensic Substance Database on Explosives. Forensic Science International, 308, 110180. doi: 10.1016/j.forsciint.2020.110180.
- . (). Mass Spectrometry Imaging of atherosclerosis-affine Gadofluorine following Magnetic Resonance Imaging. Scientific Reports, 10, 79. doi: 10.1038/s41598-019-57075-6.
- . (). Gadolinium deposition in the brain of dogs after multiple intravenous administrations of linear gadolinium based contrast agents. PloS one, 15(2), e0227649. doi: 10.1371/journal.pone.0227649.
- . (). Effect of Long-Term Retention of Gadolinium on Metabolism of Deep Cerebellar Nuclei After Repeated Injection of Gadolinium in Rats. Investigative Radiology, 55(2), 120–128. doi: 10.1097/RLI.0000000000000621.
- . (). Multimodal imaging of hallucinogens 25C- and 25I-NBOMe on blotter papers. Drug Testing and Analysis, 12, 465–471. doi: 10.1002/dta.2751.
- . (). Analysis of rare-earth metals and their species. In (Eds.), Rare Earth Chemistry (pp. 225–234). Berlin/Munich/Boston: De Gruyter. doi: 10.1515/9783110654929-016.
- . (). Fast Online Separation and Identification of Electrochemically Generated Isomeric Oxidation Products by Trapped Ion Mobility-Mass Spectrometry. Analytical Chemistry, 92(1), 1205–1210. doi: 10.1021/acs.analchem.9b04337.
- . (). Simultaneous Detection of Zinc and Its Pathway Metabolites Using MALDI MS Imaging of Prostate Tissue. Analytical Chemistry, 92(4), 3171–3179. doi: 10.1021/acs.analchem.9b04903.
- . (). Toward precise arterial input functions derived from DCE-MRI through a novel extracorporeal circulation approach in mice. Magnetic Resonance in Medicine, 84(3), 1404–1415. doi: 10.1002/mrm.28214.
- . (). Noninvasive imaging of vascular permeability to predict the risk of rupture in abdominal aortic aneurysms using an album-inbinding probe. Scientific Reports, 10(1), 3231. doi: 10.1038/s41598-020-59842-2.
- . (). Detection of doxorubicin, cisplatin and therapeutic antibodies in formalin-fixed paraffin-embedded human cancer cells. Histochemistry and Cell Biology, 153(5), 367–377. doi: 10.1007/s00418-020-01857-x.
- . (). Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity. Scientific Reports, 10(1), 5889. doi: 10.1038/s41598-020-62039-2.
- . (). About the selectivity and reactivity of active nickelelectrodes in C–C coupling reactions. RSC Advances, 10(24), 14249–14253. doi: 10.1039/d0ra02673e. [online first]
- . (). Electrochemically Simulated Oxidative Metabolization Pattern of Neurokinin-1 Antagonist Aprepitant. Journal of The Electrochemical Society, 167(8), 085502. doi: 10.1149/1945-7111/ab927a.
- . (). Fast simultaneous quantification of gabapentin and cetirizine in cell lysates by means of HPLC-MS/MS. Journal of Pharmaceutical and Biomedical Analysis, 184, 113172. doi: 10.1016/j.jpba.2020.113172.
- . (). Preclinical evaluation of platinum-loaded hydroxyapatite nanoparticles in an embryonic zebrafish xenograft model. Nanoscale, 12(25), 13582–13594. doi: 10.1039/d0nr04064a.
- . (). Ex vivo magnetic particle imaging of vascular inflammation in abdominal aortic aneurysm in a murine model. Scientific Reports, 10(1), 12410. doi: 10.1038/s41598-020-69299-y.
- . (). Is Small Fiber Neuropathy Induced by Gadolinium-Based Contrast Agents? Investigative Radiology, 55(8), 473–480. doi: 10.1097/RLI.0000000000000677.
- . (). Hydroperoxylated vs Dihydroxylated Lipids: Differentiation of Isomeric Cardiolipin Oxidation Products by Multidimensional Separation Techniques. Analytical Chemistry, 92(17), 12010–12016. doi: 10.1021/acs.analchem.0c02605.
- . (). LC-ICP-MS method for the determination of "extractable copper" in serum. Metallomics, 12(9), 1348–1355. doi: 10.1039/d0mt00132e.
- . (). Mass-Spectrometric Imaging of Electrode Surfaces-a View on Electrochemical Side Reactions. Angewandte Chemie - International Edition, 59(46), 20428–20433. doi: 10.1002/anie.202010134.
- . (). Simultaneous molecular MRI of extracellular matrix collagen and inflammatory activity to predict abdominal aortic aneurysm rupture. Scientific Reports, 10(1), 15206. doi: 10.1038/s41598-020-71817-x.
- . (). A mass spectrometry-based approach gives new insight into organotin–protein interactions. Metallomics, 12(11), 1701–1712. doi: 10.1039/d0mt00171f.
- . (). Phytoremediation of soil contaminated with lithium ion battery active materials – A proof of concept study. Recycling, 5 (4)(Special Issue: Recycling of Lithium Ion Batteries and Other Next Generation Materials), 26. doi: 10.3390/recycling5040026.
- . (). Elemental bioimaging of Na distribution in roots of Arabidopsis thaliana using laser ablation-ICP-MS under cold plasma conditions. Journal of Analytical Atomic Spectrometry, 35(9), 2057–2063. doi: 10.1039/D0JA00151A.
- . (). Complementary approach for analysis of phospholipids by liquid chromatography hyphenated to elemental and molecular mass spectrometry. Analytical Science Advances, 1, 46–55. doi: 10.1002/ansa.20190009.
- . (). Revealing Silver Nanoparticle Uptake by Macrophages using SR-µXRF and LA-ICP-MS. Chemical Research in Toxicology, 33(5), 1250–1255. doi: 10.1021/acs.chemrestox.9b00507.
- . (). Acylated 1H-1,2,4-Triazol-5-amines Targeting Human Coagulation Factor XIIa and Thrombin: Conventional and Microscale Synthesis, Anticoagulant Properties, and Mechanism of Action. Journal of Medicinal Chemistry, 63(21), 13159–13186. doi: 10.1021/acs.jmedchem.0c01635.
- . (). Molecular MR-Imaging for Noninvasive Quantification of the Anti-Inflammatory Effect of Targeting Interleukin-1 beta in a Mouse Model of Aortic Aneurysm. Molecular Imaging, 19. doi: 10.1177/1536012120961875.
- . (). Assessment of the hepatic tumor extracellular matrix using elastin-specific molecular magnetic resonance imaging in an experimental rabbit cancer model. Scientific Reports, 10(1). doi: 10.1038/s41598-020-77624-8.
- . (). Alginate aerogels carrying calcium, zinc and silver cations for wound care: Fabrication and metal detection. Journal of Supercritical Fluids, 153, 104545. doi: 10.1016/j.superflu.2019.104545.
- . (). Concurrent Molecular Magnetic Resonance Imaging of Inflammatory Activity and Extracellular Matrix Degradation for the Prediction of Aneurysm Rupture. CIRCULATION-CARDIOVASCULAR IMAGING, 12(3), e008707. doi: 10.1161/CIRCIMAGING.118.008707.
- . (). Introducing specificity to iron oxide nanoparticles imaging by combining 57Fe-based MRI and mass spectrometry . Nano Letters, 19(11), 7908–7917. doi: 10.1016/j.devcel.2019.01.006.
- . (). Compound-specific adaptation of hepatoma cell lines to toxic iron . Metallomics, 11(11), 1836–1846. doi: 10.1039/c9mt00202b.
- . (). Allergic reaction to a green tattoo with nickel as a possible allergen. Contact Dermatitis, 81(1), 64–66. doi: 10.1111/cod.13226.
- . (). Gadolinium Deposition in the Brain in a Large Animal Model: Comparison of Linear and Macrocyclic Gadolinium-Based Contrast Agents . Investigative Radiology, 54(9), 531–536. doi: 10.1097/RLI.0000000000000575.
- . (). Effects of Single Nucleotide Polymorphism Ala270Ser (rs316019) on the Function and Regulation of hOCT2. Biomolecules, 9(10), 578. doi: 10.3390/biom9100578.
- . (). An integrative approach to cisplatin chronic toxicities in mice reveals importance of organic cation-transporter-dependent protein networks for renoprotection. Archives of Toxicology, 93(10), 2835–2848. doi: 10.1007/s00204-019-02557-9.
- . (). Quantitative imaging of platinum-based antitumor complexes in bone tissue samples using LA-ICP-MS. Journal of Trace Elements in Medicine and Biology, 54, 98–102. doi: 10.1016/j.jtemb.2019.04.011.
- . (). LA-ICP-MS/MS improves limits of detection in elemental bioimaging of gadolinium deposition originating from MRI contrast agents in skin and brain tissues. Journal of Trace Elements in Medicine and Biology, 51, 212–218. doi: 10.1016/j.jtemb.2018.10.021.
- . (). Quantitative dried blood spot analysis for metallodrugs by laser ablation inductively coupled plasma-mass spectrometry. Journal of Trace Elements in Medicine and Biology, 51, 50–56. doi: 10.1016/j.jtemb.2018.09.009.
- . (). A High-Calorie Diet Aggravates Mitochondrial Dysfunction and Triggers Severe Liver Damage in Wilson Disease Rats. Cellular and molecular gastroenterology and hepatology (CMGH), 7(3), 571–596. doi: 10.1016/j.jcmgh.2018.12.005.
- . (). Molecular and electrophysiological analysis of platinum-induced neurotoxicity using the model organism C. elegans. Naunyn-Schmiedeberg's Archives of Pharmacology, 392(1), S63.
- . (). LA-ICP-TOF-MS for rapid, all-elemental and quantitative bioimaging, isotopic analysis and the investigation of plasma processes. Journal of Analytical Atomic Spectrometry, 34(4), 694–701. doi: 10.1039/c8ja00288f.
- . (). Spatially resolved analysis of liquid crystal displays by laser ablation-atmospheric pressure chemical ionization-mass spectrometry. Analytica Chimica Acta, 1055, 56–64. doi: 10.1016/j.aca.2018.12.048.
- . (). CIPK11-Dependent Phosphorylation Modulates FIT Activity to Promote Arabidopsis Iron Acquisition in Response to Calcium Signaling. Developmental Cell. doi: 10.1016/j.devcel.2019.01.006.
- . (). Introducing specificity to iron oxide nanoparticle imaging by combining 57Fe-based MRI and mass spectrometry. Nano Letters, 19(11), 7908–7917. doi: 10.1021/acs.nanolett.9b03016.
- (). Bioimaging of the elemental distribution in cocoa beans by means of LA-ICP-TQMS. Journal of Analytical Atomic Spectrometry, 33(2), 187–194. doi: 10.1039/c7ja00354d.
- (). Spatially resolved quantification of gadolinium deposited in the brain of a patient treated with gadolinium-based contrast agents. Journal of Trace Elements in Medicine and Biology, 45(null), 125–130. doi: 10.1016/j.jtemb.2017.10.004.
- (). Organic cation transporter 3 mediates cisplatin and copper cross-resistance in hepatoma cells. Oncotarget, 9(1), 743–754. doi: 10.18632/oncotarget.23142.
- (). Leaded Bronze: An Innovative Lead Substitute for Cathodic Electrosynthesis. ChemElectroChem, 5(2), 247–252. doi: 10.1002/celc.201701061.
- (). Analysis of metal-based contrast agents in medicine and the environment. TrAC - Trends in Analytical Chemistry, null(null). doi: 10.1016/j.trac.2017.12.011. [online first]
- . (). Multimodal laser ablation/desorption imaging analysis of Zn and MMP-11 in breast tissues. Analytical and Bioanalytical Chemistry, 410(3), 913–922. doi: 10.1007/s00216-017-0537-x.
- . (). High spatial resolution LA-ICP-MS demonstrates massive liver copper depletion in Wilson disease rats upon Methanobactin treatment. Journal of Trace Elements in Medicine and Biology, 49, 119–127. doi: 10.1016/j.jtemb.2018.05.009.
- . (). Investigations on the binding of ethylmercury from thiomersal to proteins in influenza vaccines. Journal of Trace Elements in Medicine and Biology, 50, 100–104. doi: 10.1016/j.jtemb.2018.06.011.
- . (). Identification of potent drug candidates for the prevention of cisplatin-induced neurotoxicity in the model organism C. elegans. Naunyn-Schmiedeberg's Archives of Pharmacology, 391(1), S4.
- . (). Direct Photolysis of Sulfamethoxazole Using Various Irradiation Sources and Wavelength Ranges-Insights from Degradation Product Analysis and Compound-Specific Stable Isotope Analysis. Environmental Science and Technology, 52(3), 1225–1233. doi: 10.1021/acs.est.7b04744.
- . (). Active Molybdenum-Based Anode for Dehydrogenative Coupling Reactions. Angewandte Chemie - International Edition, 57(9), 2450–2454. doi: 10.1002/anie.201712718.
- . (). Quantitative imaging of translocated silver following nanoparticle exposure by laser ablation-inductively coupled plasma-mass spectrometry (vol 10, pg 836, 2018). Analytical Methods, 10(8), 926. doi: 10.1039/c8ay90014k.
- . (). Quantitative imaging of translocated silver following nanoparticle exposure by laser ablation-inductively coupled plasma-mass spectrometry. Analytical Methods, 10(8), 836–840. doi: 10.1039/c7ay02294h.
- . (). Comparison of metabolic pathways of different alpha-N-heterocyclic thiosemicarbazones. Analytical and Bioanalytical Chemistry, 410(9), 2343–2361. doi: 10.1007/s00216-018-0889-x.
- . (). Combination of micro X-ray fluorescence spectroscopy and time-of-flight secondary ion mass spectrometry imaging for the marker-free detection of CeO2 nanoparticles in tissue sections. Journal of Analytical Atomic Spectrometry, 33(3), 491–501. doi: 10.1039/c7ja00325k.
- . (). Laser Ablation-Aerosol Mass Spectrometry-Chemical Ionization Mass Spectrometry for Ambient Surface Imaging. Analytical Chemistry, 90(6), 4046–4053. doi: 10.1021/acs.analchem.7b05255.
- . (). Structure elucidation and quantification of the reduction products of anticancer Pt(iv) prodrugs by electrochemistry/mass spectrometry (EC-MS). Analyst, 143(9), 1997–2001. doi: 10.1039/c8an00258d.
- . (). Interaction of the New Monofunctional Anticancer Agent Phenanthriplatin With Transporters for Organic Cations. Frontiers in Chemistry, 6. doi: 10.3389/fchem.2018.00180.
- . (). Quantitative Bioimaging of Platinum via Online Isotope Dilution Laser Ablation-Inductively Coupled Plasma Mass Spectrometry. Analytical Chemistry, 90(11), 7033–7039. doi: 10.1021/acs.analchem.8b01429.
- . (). Visualizing protoporphyrin IX formation in the dura tail of meningiomas by mass spectrometry imaging. Acta Neurochirurgica, 160(7), 1433–1437. doi: 10.1007/s00701-018-3488-x.
- . (). Gadolinium-based contrast agents induce gadolinium deposits in cerebral vessel walls, while the neuropil is not affected: an autopsy study. Acta Neuropathologica, 136(1), 127–138. doi: 10.1007/s00401-018-1857-4.
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- . (). Determination of the excretion kinetics of Gd-based MRT-contrast agents by means of HILIC/ICP-MS and CE/ESI-ToF-MS. In 118th BASF Summer Course, Ludwigshafen.
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- . (). Development of a countergradient parking system for gradient liquid chromatography with online biochemical detection of serine protease inhibitors. Analytical Chemistry, 80(17), 6764–6772.
- . (). Capillary electrophoresis with inductively coupled plasma-mass spectrometric and electrospray time of flight mass spectrometric detection for the determination of arsenic species in fish samples. Electrophoresis, 29(12), 2731–2737.
- . (). Liquid chromatography-mass spectrometry: the long road from instrumental developments to applications. Analytical and Bioanalytical Chemistry, 391(1), 7–8. doi: 10.1007/s00216-008-2028-6.
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- . (). HPLC mit biochemischer Detektion (BCD). GIT Labor-Fachzeitschrift, 52(04/2008), 365–368.
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- . (). Analysis of cysteine-containing proteins using precolumn derivatization with N-(2-ferroceneethyl)maleimide and liquid chromatography/electrochemistry/ mass spectrometry. Analytical and Bioanalytical Chemistry, 388(8), 1633–1642. doi: 10.1007/s00216-007-1260-9.
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- . (). Generation and identification of reactive metabolites by electrochemistry and immobilized enzymes coupled on-line to liquid chromatography/mass spectrometry. Analytical Chemistry, 79(17), 6831–6839. doi: 10.1021/ac071100r.
- . (). From the test to the mass spectrometer / Aus der Probe ins Massenspektrometer. Nachrichten aus der Chemie, 55(4), 420–424.
- . (). Quantitative analysis of thiols in consumer products on a microfluidic CE chip with fluorescence detection. Electrophoresis, 28(7), 1154–1160.
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- . (). Determination of airborne isocyanates. Analytical and Bioanalytical Chemistry, 387(1), 219–236.
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- . (). Effects of humidity and filter material on diffusive sampling of isocyanates using reagent-coated filters. Journal of Environmental Monitoring, 8(10), 1014–1019. doi: 10.1039/b607658k.
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- . (). Determination of peroxide-based explosives using liquid chromatography with on-line infrared detection. Analytical Chemistry, 78(23), 8150–8155.
- . (). Simulation of the detoxification of paracetamol using on-line electrochemistry/liquid chromatography/mass spectrometry. Analytical and Bioanalytical Chemistry, 386(6), 1701–1708. doi: 10.1007/s00216-006-0801-y.
- . (). Validation of a diffusive sampling method for airborne low-molecular isocyanates using 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole-impregnated filters and liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, 1134(1-2), 112–121.
- . (). Recent methods for the determination of peroxide-based explosives. Analytical and Bioanalytical Chemistry, 386(3), 559–565. doi: 10.1007/s00216-006-0579-y.
- . (). Passive sampling of airborne peroxyacetic acid. Analytical Chemistry, 78(18), 6547–6555.
- . (). Where the worlds of nanotechnology, materials science, and bioanalysis converge. Analytical and Bioanalytical Chemistry, 384(3), 559–559. doi: 10.1007/s00216-005-0262-8.
- . (). Analysis of microperoxidases using liquid chromatography, post-column substrate conversion and fluorescence detection. Journal of Chromatography B, 830(1), 47–53.
- . (). Training and testing explosive detection dogs in detecting TATP. Forensic Sci. Commun., 2006(8).
- . (). A pleading for chromatography. G.I.T. Laboratory Journal, 6, 22–23.
- . (). Kontrolle von Bioassays durch Massenspektrometrie. Laborpraxis, 11, 22–24.
- . (). From fundamentals to applications: recent developments of atmospheric pressure photoionization mass spectrometry. Analytical and Bioanalytical Chemistry, 384(1), 85–99. doi: 10.1007/s00216-005-0046-1.
- . (). Labeling strategies for bioassays. Analytical and Bioanalytical Chemistry, 384, 572–583.
- (). Determination of telmisartan in human blood plasma: Part II: Liquid chromatography-tandem mass spectrometry method development, comparison to immunoassay and pharmacokinetic study. Analytica Chimica Acta, 560(null), 41–49. doi: 10.1016/j.aca.2005.12.035.
- (). Determination of telmisartan in human blood plasma: Part I: Immunoassay development. Analytica Chimica Acta, 560(null), 35–40. doi: 10.1016/j.aca.2005.12.036.
- . (). Assessing protease activity pattern by means of multiple substrate ESI-MS assays. Analyst, 130(6), 850–854. doi: 10.1039/b502008e.
- . (). Liquid chromatographic/mass spectrometric investigation on the reaction products in the peroxidase-catalyzed oxidation of o-phenylenediamine by hydrogen peroxide. Analytical and Bioanalytical Chemistry, 382(1), 234–238. doi: 10.1007/s00216-005-3178-4.
- . (). Bilayer vesicles of amphiphilic cyclodextrins: Host membranes that recognize guest molecules. Chemistry - A European Journal, 11(4), 1171–1180. doi: 10.1002/chem.200400905.
- . (). Screening for proteolytic activities in snake venom by means of a multiplexing electrospray ionization mass spectrometry assay scheme. Rapid Communications in Mass Spectrometry, 19, 2923–2928. doi: 10.1002/rcm.2136.
- . (). Fluorescence and mass spectrometric detection schemes for simultaneous enzymatic conversions: method development and comparison. Analytica Chimica Acta, 543, 137–142. doi: 10.1016/j.aca.2005.04.038.
- . (). Turbulent flow chromatography for the reduction of matrix effects in electrospray ionization mass spectrometry-based enzyme assays. Journal of Separation Science, 28, 1658–1665.
- . (). Chip-based on-line nanospray MS method enabling study of the kinetics of isocyanate derivatization reactions. Analytical Chemistry, 77(21), 6852–6856. doi: 10.1021/ac050817g.
- . (). Electrochemical, chemical and enzymatic oxidations of phenothiazines. Electroanalysis, 2005(17), 1501–1510. doi: 10.1002/elan.200403253.
- . (). Prediction of clozapine metabolism by on-line electrochemistry/liquid chromatography/mass spectrometry. Analytical and Bioanalytical Chemistry, 382, 742–750. doi: 10.1007/s00216-005-3053-3.
- . (). Analytik unpolarer Verbindungen mittels LC/Elektrochemie/MS. Nachr. Chem., 53, 1145–1147.
- . (). Liquid chromatography/electron capture-atmospheric pressure chemical ionization mass spectrometry. Analytical and Bioanalytical Chemistry, 382(8), 1744–1746. doi: 10.1007/s00216-005-3328-8.
- . (). Monitoring enzymatic conversions by mass spectrometry - a critical review. Anal. Bioanal. Chem., 382, 1451–1464. doi: 10.1007/s00216-005-3305-2.
- . (). Liquid chromatography/electrochemistry/mass spectrometry as screening technique for alcohols and phenols in fuels. Microchimica Acta, 146(2), 137–147.
- . (). Liquid Chromatography/Coordination Ion Spray-Mass Spectrometry for the Analysis of Rubber Vulcanization Products. Analytical Chemistry, 76(4), 1063–1068. doi: 10.1021/ac035017p.
- . (). Liquid chromatographic-mass spectrometric studies on the in vitro degradation of a poly(ether ester) block copolymer. Journal of Chromatography A, 1029(null), 29–36. doi: 10.1016/j.chroma.2003.12.056.
- . (). In vivo and in vitro degradation of poly(ether ester) block copolymers based on poly(ethylene glycol) and poly(butylene terephthalate). Biomaterials, 25(2), 247–258. doi: 10.1016/S0142-9612(03)00495-2.
- . (). A tripod ligand as new sensitiser for the enzyme amplified lanthanide luminescence determination of esterase. Analyst, 128(1), 29–31.
- . (). Effects of buffering conditions and culture pH on production rates and glycosylation of clinical phase I anti-melanoma mouse IgG3 monoclonal antibody R24. Biotechnology and Bioengineering, 83(3), 321–34. doi: 10.1002/bit.10673.
- (). Recent developments in the determination of form-aldehyde in air samples using derivatizing agents. Gefahrstoffe Reinhaltung der Luft, 63(null), 295–298.
- . (). Liquid chromatography with on-line electrochemical derivatization and fluorescence detection for the determination of phenols. Analytical Chemistry, 75(4), 922–926. doi: 10.1021/ac0204808.
- . (). LC-electron capture-APCI(-)-MS determination of nitrobenzoxadiazole derivatives. Analyst, 128(11), 1365–1372. doi: 10.1039/b308752b.
- . (). Analysis of phenothiazine and its derivatives using LC/electrochemistry/MS and LC/electrochemistry/fluorescence. Analytical Chemistry, 75(18), 4833–4840. doi: 10.1021/ac0346050.
- . (). Selective determination of hydrogen peroxide by adduct formation with a dinuclear iron(III) complex and flow injection analysis/tandem mass spectrometry. Analyst, 127(11), 1410–1412.
- . (). LC-electron capture APCI-MS for the determination of nitroaromatic compounds. Analyst, 127(8), 1027–1030. doi: 10.1039/b205477a.
- . (). Characterization of chemical interferences in the determination of unsaturated aldehydes using aromatic hydrazine reagents and liquid chromatography. Journal of Environmental Monitoring, 3(3), 306–310.
- . (). Enzyme-linked immunosorbent assays based on peroxidase labels and enzyme-amplified lanthanide luminescence detection. Analyst, 126(2), 175–178.
- . (). Liquid chromatography with post-column electrochemical treatment and mass spectrometric detection of non-polar compounds. Analyst, 126(3), 288–290.
- . (). Determination of paracetamol (acetaminophen) by HPLC with post-column enzymatic derivatization and fluorescence detection. Chromatographia, 54(3-4), 163–167.
- . (). Synthesis and application of 4-(N,N-dimethylaminosulfonyl)-7-N-methylhydrazino-2,1,3-benzoxadiazole (MDBDH) as a new derivatizing agent for aldehydes. Fresenius' Journal of Analytical Chemistry, 369(1), 47–53.
- . (). Determination of carbonyl compounds in waters using triazine-based hydrazine reagents and liquid chromatography. Analyst, 125(3), 433–438.
- . (). Peroxidase enhanced lanthanide luminescence - a new technique for the evaluation of bioassays. Analyst, 125(9), 1537–1538.
- . (). Post-column oxidative derivatization for the liquid chromatographic determination of phenothiazines. Journal of Chromatography A, 890(2), 281–287.
- . (). Characterization of a chemical artifact in the liquid chromatographic determination of 3-butyn-2-one using the 2,4-dinitrophenylhydrazine method. Journal of Chromatography A, 886(1-2), 303–307.
- . (). Hydrazine reagents as derivatizing agents in environmental analysis - a critical review. Fresenius' Journal of Analytical Chemistry, 366(8), 781–791. doi: 10.1007/s002160051572.
- . (). 4-(N-Methylhydrazino)-7-nitro-2,1,3-benzooxadiazole (MNBDH): A Novel Fluorogenic Peroxidase Substrate. Angewandte Chemie - International Edition, 39(8), 1453–1455.
- . (). Tailor-made derivatizing agents for carbonyl compounds using liquid chromatography. Analytica Chimica Acta, 410(1-2), 47–64.
- . (). ANAKON '99: A preview of tomorrow's Analytical Chemistry. Fresenius' Journal of Analytical Chemistry, 366(4), 323–323. doi: 10.1007/s002160050064.
- . (). Spectrophotometric and direct-reading methods for the analysis of gas phase peroxyacetic acid. Fresenius' Journal of Analytical Chemistry, 366(4), 361–364.
- . (). Determination of acetaldehyde in tobacco smoke using N-methyl-4-hydrazino-7-nitrobenzofurazan and liquid chromatography/mass spectrometry. Fresenius' Journal of Analytical Chemistry, 366(4), 396–9. doi: 10.1007/s002160050081.
- . (). 2,4-dinitro-3,5,6-trideuterophenylhydrazones for the quantitation of aldehydes and ketones in air samples by liquid chromatography-mass spectrometry. Journal of Chromatography A, 869(1-2), 251–259.
- . (). Determination of glucose in soft drinks using its enzymatic oxidation and the detection of formed hydrogen peroxide with a dinuclear iron(III) complex. Analytica Chimica Acta, 401(1-2), 83–90. doi: 10.1016/S0003-2670(99)00514-0.
- . (). Flow injection analysis of hydrogen peroxide in disinfectants. Fresenius' Journal of Analytical Chemistry, 364(1-2), 184–188. doi: 10.1007/s002160051321.
- . (). Formation of aqueous small droplet aerosols assisted by supercritical carbon dioxide. Aerosol Science and Technology, 30(1), 3–15.
- . (). HPLC-APCI-MS with calibration based on stable isotope-labelled internal standards for the quantification of carbonyls in air samples. Analyst, 124(9), 1291–1295. doi: 10.1039/a904393d.
- . (). N-methyl-4-hydrazino-7-nitrobenzofurazan as a new reagent for air monitoring of aldehydes and ketones. Analytical Chemistry, 71(9), 1893–1898. doi: 10.1021/ac980946f.
- . (). Rapid and selective determination of peroxyacetic acid in disinfectants using flow injection analysis. Analytica Chimica Acta, 389(1-3), 233–238. doi: 10.1016/S0003-2670(99)00156-7.
- . (). Workplace monitoring of gas phase hydrogen peroxide by means of fluorescence spectroscopy. Analytica Chimica Acta, 401(1-2), 191–196. doi: 10.1016/S0003-2670(99)00488-2.
- . (). Workplace monitoring of oximes using 2,4-dinitrophenylhydrazine-coated silica gel cartridges and liquid chromatography. Analytica Chimica Acta, 388(1-2), 181–186. doi: 10.1016/S0003-2670(99)00128-2.
- . (). Zeitverzögerte fluoreszenzspektroskopie mit Lanthanoidkomplexen - Prinzipien und Anwendungen. Nachrichten aus der Chemie, 47(9), 1116–1119.
- . (). Liquid chromatography-mass spectrometry method for the determination of aldehydes derivatized by the Hantzsch reaction. Journal of Chromatography A, 864(2), 191–197.
- . (). Determination of gas phase peroxyacetic acid using pre-column derivatization with organic sulfide reagents and liquid chromatography. Journal of Chromatography A, 855(2), 551–561.
- . (). Determination of carbonyls using liquid chromatography-mass spectrometry with atmospheric pressure chemical ionization. Journal of Environmental Monitoring, 1(4), 307–311.
- . (). Determination of nitrite in waters by microplate fluorescence spectroscopy and HPLC with fluorescence detection. Analytical Chemistry, 71(15), 3003–3007.
- . (). A diffusive sampling device for the determination of formaldehyde in air using N-methyl-4-hydrazino-7-nitrobenzofurazan (MNBDH) as reagent. Journal of Environmental Monitoring, 1(1), 39–43.
- . (). Analytical reliability of carbonyl compound determination using 1,5-dansylhydrazine-derivatization. Fresenius' Journal of Analytical Chemistry, 362(3), 270–273. doi: 10.1007/s002160051072.
- . (). Liquid chromatographic simultaneous determination of peroxycarboxylic acids using postcolumn derivatization. Analytical Chemistry, 70(18), 3857–3862. doi: 10.1021/ac980256b.
- . (). Peroxide analysis in laundry detergents using liquid chromatography. Analytica Chimica Acta, 363(1), 97–103. doi: 10.1016/S0003-2670(98)00040-3.
- . (). Reagent for the high-performance liquid chromatography determination of peroxycarboxylic acids. Analyst, 123(8), 1761–1765. doi: 10.1039/a801697f.
- . (). 1-Methyl-1-(2,4-dinitrophenyl)hydrazine as a New Reagent for the HPLC Determination of Aldehydes. Analytical Chemistry, 69(17), 3617–3622. doi: 10.1021/ac970146p.
- . (). Microplate photometric determination of aldehydes in disinfectant solutions. Analytica Chimica Acta, 351(1-3), 247–257. doi: 10.1016/S0003-2670(97)00363-2.
- . (). Non-porous silica for ultrafast reversed-phase high-performance liquid chromatographic separation of aldehyde and ketone 2,4-dinitrophenylhydrazones. Journal of Chromatography A, 786(1), 47–55. doi: 10.1016/S0021-9673(97)00564-5.
- . (). Selective photometric determination of peroxycarboxylic acids in the presence of hydrogen peroxide. Analyst, 122(6), 567–571. doi: 10.1039/a700509a.
- . (). Simultaneous HPLC Determination of Peroxyacetic Acid and Hydrogen Peroxide. Analytical Chemistry, 69(17), 3623–3627. doi: 10.1021/ac9701750.
- . (). Modular derivatisation reagents designed on purpose for ambient air monitoring of volatile substances: I. aldehydes and ketones. Zentralblatt fur Hygiene und Umweltmedizin, 200(4), 364–365.
- . (). An unsymmetrical dinuclear iron(III) complex with peroxidase properties. Angewandte Chemie - International Edition, 35(17), 1973–1974. doi: 10.1002/anie.199619731.
- . (). Identification of Chemical Interferences in Aldehyde and Ketone Determination Using Dual-Wavelength Detection. Analytical Chemistry, 68(19), 3354–3358. doi: 10.1021/ac960319v.
- . (). Rapid high-performance liquid chromatographic method for the determination of peroxyacetic acid. Journal of Chromatography A, 730(1-2), 203–208. doi: 10.1016/0021-9673(95)01346-6.
- . (). Determination of peroxyacetic acid using high-performance liquid chromatography with external calibration. Analytical Chemistry, 66(15), 2599–2600. doi: 10.1021/ac00087a028.
- . (). Development of a method for simultaneous determinations of nitrogen oxides, aldehydes and ketones in air samples. Journal of Chromatography A, 653(2), 341–347. doi: 10.1016/0021-9673(93)83193-V.
- . (). Interferences of nitrogen dioxide in the determination of aldehydes and ketones by sampling on 2,4-dinitrophenylhydrazine-coated solid sorbent. Fresenius' Journal of Analytical Chemistry, 345(1), 48–52. doi: 10.1007/BF00323325.
Supervised Doctoral Studies
Bien, Tanja Neue Anwendungen von laserinduzierter Nachionisation für die bildgebende Matrix-unterstützte Laser-Desorption-/Ionisation in der biologischen Massenspektrometrie Brockmann, Eike New Methods for MALDI Mass Spectrometry Imaging of Bacteria Bookmeyer, Christoph Hauke Manfred Entwicklung und Charakterisierung einer Ionenquelle mit Nachionisationsmodulen für die biomedizinische Massenspektrometrie Boskamp, Marcel Systematische Untersuchung des Ionenunterdrückungseffekts von Glycerophospholipiden in der bildgebenden MALDI-Massenspektrometrie Eiersbrock, Fabian Laser-Mikrodissektion zur Kombination von MALDI-MSI und nanoHPLC-MS für die Analyse ausgewählter Membranlipidverteilungen im Maushirn Vens-Cappell, Simeon Methoden zur Vermeidung von Ionensuppression in der bildgebenden Matrix-unterstützen Laserdesorption/-ionisation unter besonderer Berücksichtigung der neutralen Glykosphingolipide Crone, Barbara Multimodal Bioimaging - Combining Mass Spectrometric, Spectroscopic and Microscopic Techniques Steckhan, Katja Berit Strukturelle und funktionelle Charakterisierung von Glykosphingolipiden mit Hilfe einer Kombination von Immundetektion und Desorptions-Elektrosprayionisation Fouriertransform-Ionenzyklotronresonanz-Massenspektrometrie Koch, Annika Untersuchungen zu Wellenlängenabhängigkeiten in der Laser-Massenspektrometrie unter Vakuum- und Atmosphärendruckbedingungen Schnapp, Andreas Mechanismusuntersuchung und Weiterentwicklung von Laser-Desorptions-/Ionisationsmethoden in der Massenspektrometrie zur Erweiterung der analysierbaren Stoffklassen Viehoff, Maria Analytical Methods to Study the Degradation of Iodine-containing Pharmaceuticals Elseberg, Tim Laser Ablation-Ambient Ionization-Mass Spectrometry and Micro X-Ray Fluorescence Imaging as Orthogonal Techniques for the Analysis of Pharmaceuticals Frensemeier, Lisa Strategies for the identification and quantification of electrochemically generated drug metabolites Thyssen, Georgina Bioimaging of Nutritional and Toxic Elements in Plant Samples - Overcoming Interferences and Contaminations Clases, David Trace Metals in Medicine and the Environment - Hyphenated Techniques for Speciation Analysis and Bioimaging Hachmöller, Oliver Elemental Bioimaging by Mass Spectrometric and X-Ray Based Methods for the Investigation of Wilson's Disease Staniford, Gina Clay platelets for smart photonic particles Harkai, Sara Schnelle und zerstörungsfreie Analytik von Arzneimittelwirkstoffen, Betäubungsmitteln und Designerdrogen in der Kriminaltechnik Christian Paul Ortmeyer Synthesis, optimization and evaluation of bordipyrromethene-fluorophores for the preparation of ligands for multimodal imaging Wigger, Tina Hyphenated Techniques to Study the Metabolic and Environmental Fate of Polycyclic Aromatic Hydrocarbons Großgarten, Mandy Chemical Imaging Analysis in Biomedical Research: Elucidating the Fate of Nanoparticles and Heavy Metals in the Organism Bülter, Ann-Christin Elemental and Molecular Mass Spectrometry for Complementary Bioimaging: From Method Development to Biomedical Applications Mak, Chun Kong Identification and Quantification of Electrochemical Oxidation Products of Thyroid Hormones with Countergradient Liquid Chromatography and Mass Spectrometric Detection Hogeback, Jens Mercury Speciation Analysis: Interaction with Blood Proteins and Spatial Microanalysis in Cells Steingrobe, Tobias Entwicklung einer großflächigen Glimmentladungsquelle und eines Laserablations-Niedrigfluss-ICP-MS-Systems als neuartige elementselektive Imaging-Techniken Niehaus, Rebecca LA-ICP-MS Systems for Bioimaging: Towards Representative Sampling, Fast Washout, High Spatial Resolution and Sensitive Detection of Organic Aerosols Herdering, Christina Analytical methods for speciation analysis and imaging - Contributions to Cisplatin chemotherapy Büter, Lars Protein Modification based on Electrochemically Generated Reactive Intermediates Birka, Marvin Method Development for the Ultra Trace Speciation Analysis of Gadolinium Roscher, Jörg Investigating the UV degradation of drugs in water by means of photolysis, liquid chromatography, and mass spectrometry Meyer, Sören Instrumentelle Analytik (LC/ICPMS/MS) und toxikologische Charakterisierung von Arsenolipiden Gelhard, Carsten A Backward and Forward Consideration of the External Value Co-Creation Process: Performance Implications in the Short- and Long-Term Zlatev, Iavor Entwicklung von Nanopartikeln als Träger für Alzheimer Therapeutika Wentker, Kristina Analytical Methods to Study the Distribution of Gadolinium in Biological Samples Unterberg, Marlies Etablierung eines LC/FTMS basierten Testsystems zur Quantifizierung der epigenetische Effekte von Arsenverbindungen Wehe, Christoph Pushing inductively coupled-mass spectrometry to its limits: Towards improved sensitivity, robustness, speed and sample consumption Pieper, Imke Organoquecksilberspezies und der zelluläre DNA-Schadensresponse Dreiling, Alena Modifikationen und Interaktionen der calciumbindenden Proteine S100A8 und S100A9 in entzündlichen Erkrankungen wie Systemischer Juveniler Rheumatoider Arthritis und Familiärem Mittelmeerfieber Leffers, Larissa Bioverfügbarkeit, Metabolismus und Toxizität von Arsenozuckern Hohenester, Ulli Martin Massenspektrometrische Analyse der Phosphorylierung von Histidin in Peptiden und Proteinen und der Sulfonierung von Proteinen am beispiel von Annexin A2 Terborg, Lydia Anaytical methods for the determination of aging products in lithium-ion-batteries Baumann, Anne Investigation of the Oxidative Metabolism of Xenobiotics Electrochemical, in vitro and in vivo studies Pfeifer, Thorben A new type of low-flow ion source for ICP-MS Veldboer, Katrin Analysis of Phosphorous Containing Species in Complex Matrices Hein, Eva-Maria Revealing the Lipidome of Yeasts, Bacteria and Mammalian Cells - An Analytical Platform for Glycerophospholipid Profiling – Using Hyphenated Mass Spectrometric Techniques Bomke, Susanne Organometallic Derivatizing Agents and their Use in Bioanalysis Meermann, Björn Hyphenated Techniques for Speciation Analysis Vielhaber, Torsten Lanthanide-Based Nanoparticles: Surface Modification, Characterization and Application Zarei, Mostafa Compositional and Structural Elucidation of Glycosphingolipids by Modern Mass Spectrometry and Related Hyphenated Techniques Schebb, Nils Helge Liquid Chromatography-Mass Spectrometry for Biological Activity Detection in Complex Mixtures Nowak, Sascha New Methods and Instrumentation for Elemental Analysis in Biological Samples Trümpler, Stefan Mercury Speciation Analysis From Biomethylation in Sediments to the Antidote Therapy of Intoxications Künnemeyer, Jens Miniaturization and Hyphenation in Environmental and Pharmaceutical Analysis - Stategies, Methods and Instrumentation Lohmann, Wiebke Simulation of the Oxidative Metabolism of Pharmaceuticals Using On-Line Electrochemistry/Liquid Chromatography/Mass Spectrometry Seiwert, Bettina Ferrocene-based derivatizing agents for LC/MS and LC/EC/MS Scheffer, Andy Towards new plasma sources for trace elements determination and speciation analysis Grote, Jens Charakterisierung von Proteinen mittels Kopplung von Oberflächenplasmonen-resonanz und Massensprektrometrie (SPR-MS)