Papers


In press

Sawatzky A Tenbrinck D Jiang X Burger M. A Variational Framework for Region-Based Segmentation Incorporating Physical Noise Models. Journal of Mathematical Imaging and Vision (JMIV): in press.



2013

Bettenworth D, Reuter S, Hermann S, Weckesser M, Kerstiens L, Stratis A, Nowacki TM, Ross M, Lenze F, Edemir B, Maaser C, Pap T, Koschmieder S, Heidemann J, Schäfers M, Lugering A. Translational 18F-FDG PET/CT Imaging to Monitor Lesion Activity in Intestinal Inflammation. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2013: epub. Abstract

Corroyer-Dulmont A, Peres EA, Petit E, Guillamo J-S, Varoqueaux N, Roussel S, Toutain J, Divoux D, Mackenzie ET, Delamare J, Ibazizene M, Lecocq M, Jacobs AH, Barre L, Bernaudin M, Valable S. Detection of glioblastoma response to temozolomide combined with bevacizumab based on muMRI and muPET imaging reveals [18F]-fluoro-L-thymidine as an early and robust predictive marker for treatment efficacy. Neuro-Oncology 2013;15: 41-56. Abstract

Dawood M, Gigengack F, Jiang X, Schäfers KP. A mass conservation-based optical flow method for cardiac motion correction in 3D-PET. Medical Physics 2013;40: 012505. Abstract

Fieseler M, Kugel H, Gigengack F, Kösters T, Büther F, Quick HH, Faber C, Jiang X, Schäfers KP. A dynamic thorax phantom for the assessment of cardiac and respiratory motion correction in PET/MRI: A preliminary evaluation. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 2013;702: 59-63. Abstract

Gigengack F, Ruthotto L, Jiang X, Modersitzki J, Burger M, Hermann S, Schäfers KP. Atlas-Based Whole-Body PET-CT Segmentation using a Passive Contour Distance. Medical Computer Vision (MICCAI Workshop) 2013;7766: 82-92. Abstract

Grabner A, Kentrup D, Edemir B, Sirin Y, Pavenstädt H, Schlatter E, Schober O, Schäfers M, Schnöckel U, Reuter S. PET with 18F-FDG-Labeled T Lymphocytes for Diagnosis of Acute Rat Renal Allograft Rejection. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2013Abstract

Grabner A, Kentrup D, Schnöckel U, Gabriels G, Schröter R, Pavenstädt H, Schober O, Schlatter E, Schäfers M, Reuter S. Non-invasive imaging of acute allograft rejection after rat renal transplantation using 18F-FDG PET. J Vis Exp. 2013: e4240. Abstract

Hahnenkamp A, Schäfers M, Bremer C, Höltke C. Design and Synthesis of Small-Molecule Fluorescent Photoprobes Targeted to Aminopeptdase N (APN/CD13) for Optical Imaging of Angiogenesis. Bioconjugate Chemistry 2013: epub. Abstract

Lenz P, Bettenworth D, Krausewitz P, Brückner M, Ketelhut S, von Bally G, Domagk D, Kemper B. Digital holographic microscopy quantifies the degree of inflammation in experimental colitis. Integrative Biology 2013;5: 624-630. Abstract

Lenz P, Roggel M, Domagk D. Double- vs single-balloon enteroscopy: single center experience with emphasis on procedural performance. International Journal of Colorectal Disease 2013: epub. Abstract

Limpachayaporn P, Schäfers M, Schober O, Kopka K, Haufe G. Synthesis of new fluorinated, 2-substituted 5-pyrrolidinylsulfonyl isatin derivatives as caspase-3 and caspase-7 inhibitors: Nonradioactive counterparts of putative PET-compatible apoptosis imaging agents. Bioorganic & Medicinal Chemistry 2013;21: 2025-2036. Abstract

Meister T, Heinzow HS, Woestmeyer C, Lenz P, Menzel J, Kucharzik T, Domschke W, Domagk D. Intraductal ultrasound substantiates diagnostics of bile duct strictures of uncertain etiology. World Journal of Gastroenterology : WJG 2013;19: 874-881. Abstract

Palm T, Hemmer K, Winter J, Fricke IB, Tarbashevich K, Sadeghi Shakib F, Rudolph I-M, Hillje A-L, De Luca P, Bahnassawy L'a, Madel R, Viel T, De Siervi A, Jacobs AH, Diederichs S, Schwamborn JC. A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1-miRNA feedback loop. Nucleic Acids Research 2013;41: 3699-3712. Abstract

Paul M, Wichter T, Gerss J, Arps V, Schulze-Bahr E, Robenek H, Breithardt G, Weissen-Plenz G. Connexin Expression Patterns in Arrhythmogenic Right Ventricular Cardiomyopathy. The American Journal of Cardiology 2013: epub. Abstract

Rapic S, Backes H, Viel T, Kummer MP, Monfared P, Neumaier B, Vollmar S, Hoehn M, Van der Linden A, Heneka MT, Jacobs AH. Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease. Neurobiology of Aging 2013;34: 351-354. Abstract

Stegger L, Schülke C, Wenning C, Rahbar K, Kies P, Schober O, Schäfers M. Cardiac PET/MRI. Current Cardiovascular Imaging Reports 2013: 1-10. Abstract

Waschkau B, Faust A, Schäfers M, Bremer C. Performance of a new fluorescence-labeled MMP inhibitor to image tumor MMP activity in vivo in comparison to an MMP-activatable probe. Contrast Media & Molecular Imaging 2013;8: 1-11. Abstract

Wenning C, Rahbar K, Vrachimis A, Schober O, Schäfers M, Stegger L. Myocardial perfusion imaging and coronary calcium scoring with a two-slice SPECT/CT system: can the attenuation map be calculated from the calcium scoring CT scan?. European Journal of Nuclear Medicine and Molecular Imaging 2013: epub. Abstract


2012

Büther F, Ernst I, Hamill J, Eich HT, Schober O, Schäfers M, Schäfers KP. External radioactive markers for PET data-driven respiratory gating in positron emission tomography. European Journal of Nuclear Medicine and Molecular Imaging 2012;40: 602-614. Abstract

Büther K, Compeer MG, De Mey JG, Schober O, Schäfers M, Bremer C, Riemann B, Höltke C. Assessment of Endothelin-A Receptor Expression in Subcutaneous and Orthotopic Thyroid Carcinoma Xenografts in Vivo Employing Optical Imaging Methods. Endocrinology 2012;153: 2907-2918. Abstract

Bertrand J, Nitschke Y, Fuerst M, Hermann S, Schäfers M, Sherwood J, Nalesso G, Ruether W, Rutsch F, Dell'Accio F, Pap T. Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice. Annals of the Rheumatic Diseases 2012;71: 1249-1253. Abstract

Claesener M, Breyholz H-J, Hermann S, Faust A, Wagner S, Schober O, Schäfers M, Kopka K. Efficient synthesis of a fluorine-18 labeled biotin derivative. Nuclear Medicine and Biology 2012;39: 1189-1194. Abstract

Fabritz L, Fortmuller L, Yu TY, Paul M, Kirchhof P. Can preload-reducing therapy prevent disease progression in arrhythmogenic right ventricular cardiomyopathy? Experimental evidence and concept for a clinical trial. Progress in Biophysics and Molecular Biology 2012;110: 340-346. Abstract

Gigengack F, Ruthotto L, Burger M, Wolters C, Jiang X, Schäfers K. Motion Correction in Dual Gated Cardiac PET using Mass-Preserving Image Registration. IEEE Transactions on Medical Imaging 2012;31: 698-712. Abstract

Hermann S, Starsichova A, Waschkau B, Kuhlmann M, Wenning C, Schober O, Schäfers M. Non-FDG imaging of atherosclerosis: Will imaging of MMPs assess plaque vulnerability?. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology 2012;19: 609-617. Abstract

Hesselmann V, Niederstadt T, Dziewas R, Ritter M, Kemmling A, Maintz D, Koehler M, Seifarth H, Jacobs AH, Ringelstein EB, Heindel W. Reperfusion by Combined Thrombolysis and Mechanical Thrombectomy in Acute Stroke: Effect of Collateralization, Mismatch, and Time to and Grade of Recanalization on Clinical and Tissue Outcome. AJNR. American Journal of Neuroradiology 2012: 336-42. Abstract

Hugenberg V, Breyholz H-J, Riemann B, Hermann S, Schober O, Schäfers M, Gangadharmath U, Mocharla V, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S. A new class of highly potent matrix metalloproteinase inhibitors based on triazole-substituted hydroxamates: (radio)synthesis and in vitro and first in vivo evaluation. Journal of Medicinal Chemistry 2012;55: 4714-4727. Abstract

Hugenberg V, Haufe G. Fluoro-Pummerer rearrangement and analogous reactions. Journal of Fluorine Chemistry 2012;143: 238-262. Abstract

Jacobs AH, Tavitian B. Noninvasive molecular imaging of neuroinflammation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32: 1393-1415. Abstract

Kuhlmann MT, Cuhlmann S, Hoppe I, Krams R, Evans PC, Strijkers GJ, Nicolay K, Hermann S, Schäfers M. Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice. Journal of Visualized Experiments : JoVE 2012: 3308. Abstract

Mannweiler D. Mathematische Methoden zur Segmentierung von Kardio-MR-Zeitsequenzbildern. Diploma Thesis 2012: epub. Abstract

Paul M, Rahbar K, Gerss J, Kies P, Schober O, Schäfers K, Breithardt G, Schulze-Bahr E, Wichter T, Schäfers M. Microvascular dysfunction in nonfailing arrhythmogenic right ventricular cardiomyopathy. European Journal of Nuclear Medicine and Molecular Imaging 2012;39: 416-420. Abstract

Paulis LE, Geelen T, Kuhlmann MT, Coolen BF, Schäfers M, Nicolay K, Strijkers GJ. Distribution of lipid-based nanoparticles to infarcted myocardium with potential application for MRI-monitored drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society 2012;162: 276-285. Abstract

Rahbar K, Seifarth H, Schäfers M, Stegger L, Hoffmeier A, Spieker T, Tiemann K, Maintz D, Scheld HH, Schober O, Weckesser M. Differentiation of malignant and benign cardiac tumors using 18F-FDG PET/CT. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2012;53: 856-863. Abstract

Schrigten D, Breyholz HJ, Wagner S, Hermann S, Schober O, Schäfers M, Haufe G, Kopka K. A new generation of radiofluorinated pyrimidine-2,4,6-triones as MMP-targeted radiotracers for positron emission tomography. Journal of Medicinal Chemistry 2012: 223-232. Abstract

Szymanski MK, Kruizinga S, Tio RA, Willemsen AT, Schäfers MA, Stegger L, Dierckx RA, Hillege HL, Slart RH. Use of gated (13)N-NH(3) micro-PET to examine left ventricular function in rats. Nuclear Medicine and Biology 2012;39: 724-729. Abstract

Tenbrinck D, Schmid S, Jiang X, Schäfers K, Stypmann J. Histogram-based Optical Flow for Motion Estimation in Ultrasound Imaging. Journal of Mathematical Imaging and Vision (398) 2012: epub.

Viel T, Talasila KM, Monfared P, Wang J, Jikeli JF, Waerzeggers Y, Neumaier B, Backes H, Brekka N, Thorsen F, Stieber D, Niclou SP, Winkeler A, Tavitian B, Hoehn M, Bjerkvig R, Miletic H, Jacobs AH. Analysis of the Growth Dynamics of Angiogenesis-Dependent and -Independent Experimental Glioblastomas by Multimodal Small-Animal PET and MRI. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2012;53: 1135-1145. Abstract

Vrachimis A, Hermann S, Mathe D, Schober O, Schäfers M. Systematic evaluation of 99mTc-tetrofosmin versus 99mTc-sestamibi to study murine myocardial perfusion in small animal SPECT/CT. EJNMMI Research 2012;2: 21. Abstract

Wenning C, Stypmann J, Papavassilis P, Sindermann J, Schober O, Hoffmeier A, Scheld HH, Stegger L, Schäfers M. Left ventricular dilation and functional impairment assessed by gated SPECT are indicators of cardiac allograft vasculopathy in heart transplant recipients. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation 2012;31: 719-728. Abstract

Winkeler A, Boisgard R, Awde AR, Dubois A, Theze B, Zheng J, Ciobanu L, Dolle F, Viel T, Jacobs AH, Tavitian B. The translocator protein ligand [(18)F]DPA-714 images glioma and activated microglia in vivo. European Journal of Nuclear Medicine and Molecular Imaging 2012;39: 811-823. Abstract


2011

Baumann A, Faust A, Law MP, Kuhlmann MT, Kopka K, Schäfers M, Karst U. Metabolite identification of a radiotracer by electrochemistry coupled to liquid chromatography with mass spectrometric and radioactivity detection. Analytical Chemistry 2011;83: 5415-5421. Abstract

Brandes AA, Franceschi E, Gorlia T, Wick W, Jacobs AH, Baumert BG, van den Bent M, Weller M, Stupp R. Appropriate end-points for right results in the age of antiangiogenic agents: Future options for phase II trials in patients with recurrent glioblastoma. European Journal of Cancer (Oxford, England : 1990) 2011;48: 896–903. Abstract

Bunk EC, Stelzer S, Hermann S, Schäfers M, Schlatt S, Schwamborn JC. Cellular organization of adult neurogenesis in the Common Marmoset. Aging Cell 2011;10: 28-38. Abstract

Engbers R, Benning M, Heins P, Schäfers K, Burger M. Sparse recovery in myocardial blood flow quantification via PET. Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2011 IEEE 2011: 3742-3744.

Euskirchen P, Skaftnesmo K-O, Huszthy PC, Brekka N, Bjerkvig R, Jacobs AH, Miletic H. NUMB does not impair growth and differentiation status of experimental gliomas. Experimental Cell Research 2011;317: 2864-2873. Abstract

Fieseler M, Kosters T, Gigengack F, Braun H, Quick HH, Schäfers KP, Xiaoyi Jiang. Motion correction in PET-MRI: A human torso phantom study. Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2011 IEEE 2011: 3586-3588.

Galldiks N, Kracht LW, Dunkl V, Ullrich RT, Vollmar S, Jacobs AH, Fink GR, Schroeter M. Imaging of Non- or Very Subtle Contrast-Enhancing Malignant Gliomas with [(11)C]-methionine Positron Emission Tomography. Molecular Imaging 2011: epub. Abstract

Gigengack F, Ruthotto L, Burger M, Wolters CH, Xiaoyi Jiang, Schäfers KP. Mass-preserving motion correction of PET: Displacement field vs spline transformation. Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2011 IEEE 2011: 3088-3090.

Gigengack F, Ruthotto L, Burger M, Wolters CH, Xiaoyi Jiang, Schäfers KP. Mass-preserving motion correction of dual gated cardiac PET. Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2011 IEEE 2011: 3206-3208.

Grabner A, Schnöckel U, Kentrup D, Schäfers M, Reuter S. Strategies for Non-Invasive Molecular Imaging of Acute Allograft Rejection by Gamma Scintigraphy and Positron Emission Tomography. Current Radiopharmaceuticals 2011;4(1): 10-23. Abstract

Herzberg S, Rahbar K, Stegger L, Schäfers M, Dugas M. Concept and implementation of a computer-based reminder system to increase completeness in clinical documentation. International Journal of Medical Informatics 2011;80: 351-358. Abstract

Hutterer M, Nowosielski M, Putzer D, Waitz D, Tinkhauser G, Kostron H, Muigg A, Virgolini IJ, Staffen W, Trinka E, Gotwald T, Jacobs AH, Stockhammer G. O-(2-18F-fluoroethyl)-L-tyrosine PET predicts failure of antiangiogenic treatment in patients with recurrent high-grade glioma. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2011;52: 856-864. Abstract

Kaestle C, Winkeler A, Richter R, Sauer H, Hescheler J, Fraefel C, Wartenberg M, Jacobs AH. Imaging herpes simplex virus type 1 amplicon vector-mediated gene expression in human glioma spheroids. Molecular Imaging 2011;10: 197-205. Abstract

Kösters T, Schäfers KP, Wübbeling F. EMRECON: An expectation maximization based image reconstruction framework for emission tomography data. Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2011 IEEE 2011: 4365-4368.

Kentrup D, Reuter S, Schnöckel U, Grabner A, Edemir B, Pavenstadt H, Schober O, Schäfers M, Schlatter E, Bussemaker E. Hydroxyfasudil-mediated inhibition of ROCK1 and ROCK2 improves kidney function in rat renal acute ischemia-reperfusion injury. PloS one 2011;6: e26419. Abstract

Kies P, Paul M, Gerss J, Stegger L, Monnig G, Schober O, Wichter T, Schäfers M, Schulze-Bahr E. Impaired cardiac sympathetic innervation in symptomatic patients with long QT syndrome. European Journal of Nuclear Medicine and Molecular Imaging 2011;38: 1899-1907. Abstract

Klose A, Waerzeggers Y, Monfared P, Vukicevic S, Kaijzel EL, Winkeler A, Wickenhauser C, Löwik CWGM, Jacobs AH. Imaging bone morphogenetic protein 7 induced cell cycle arrest in experimental gliomas. Neoplasia (New York, N.Y.) 2011;13: 276-285. Abstract

Konik A, Koesters T, Madsen MT, Sunderland JJ. Evaluation of Attenuation and Scatter Correction Requirements as a Function of Object Size in Small Animal PET Imaging. IEEE Transactions on Nuclear Science 2011;58: 2308-2314.

Lindner O, Burchert W, Bengel FM, Zimmermann R, Vom Dahl J, Schäfers M. Myocardial perfusion scintigraphy in Germany in 2009: utilization and state of the practice. European Journal of Nuclear Medicine and Molecular Imaging 2011;38: 1485-1492. Abstract

Lindner O, Burchert W, Schäfers M. [High radiation exposure by myocardial scintigraphy: Is there a dosage problem?]. Deutsche Medizinische Wochenschrift (1946) 2011;136: 600. Abstract

Michel K, Büther K, Law MP, Wagner S, Schober O, Hermann S, Schäfers M, Riemann B, Höltke C, Kopka K. Development and evaluation of endothelin-A receptor (radio)ligands for positron emission tomography. Journal of Medicinal Chemistry 2011;54: 939-948. Abstract

Paul M, Wichter T, Kies P, Gerss J, Wollmann C, Rahbar K, Eckardt L, Breithardt G, Schober O, Schulze-Bahr E, Schäfers M. Cardiac Sympathetic Dysfunction in Genotyped Patients with Arrhythmogenic Right Ventricular Cardiomyopathy and Risk of Recurrent Ventricular Tachyarrhythmias. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2011;52: 1559-65. Abstract

Rueger MA, Ameli M, Li H, Winkeler A, Rueckriem B, Vollmar S, Galldiks N, Hesselmann V, Fraefel C, Wienhard K, Heiss W-D, Jacobs AH. [18F]FLT PET for non-invasive monitoring of early response to gene therapy in experimental gliomas. Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging 2011;13: 547-557. Abstract

Schellmann M, Gorlatch S, Meiländer D, Kösters T, Schäfers K, Wübbeling F, Burger M. Parallel medical image reconstruction: from graphics processing units (GPU) to grids. The Journal of Supercomputing 2011;52: 151-160. Abstract

Schmid S, Tenbrinck D, Jiang X, Schäfers K, Tiemann K, Stypmann J. Histogram-Based Optical Flow for Functional Imaging in Echocardiography. Lecture Notes in Computer Science 2011;6854/2011: 477-485. Abstract

Seidler DG, Mohamed NA, Bocian C, Stadtmann A, Hermann S, Schäfers K, Schäfers M, Iozzo RV, Zarbock A, Götte M. The role for decorin in delayed-type hypersensitivity. Journal of Immunology (Baltimore, Md. : 1950) 2011;187: 6108-6119. Abstract

van den Bent MJ, Wefel JS, Schiff D, Taphoorn MJB, Jaeckle K, Junck L, Armstrong T, Choucair A, Waldman AD, Gorlia T, Chamberlain M, Baumert BG, Vogelbaum MA, Macdonald DR, Reardon DA, Wen PY, Chang SM, Jacobs AH. Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas. The Lancet Oncology 2011;12: 583-593. Abstract

Waerzeggers Y, Monfared P, Viel T, Faust A, Kopka K, Schäfers M, Tavitian B, Winkeler A, Jacobs A. Specific biomarkers of receptors, pathways of inhibition and targeted therapies: pre-clinical developments. The British Journal of Radiology 2011;84 Spec No 2: S168-78. Abstract

Waerzeggers Y, Ullrich RT, Monfared P, Viel T, Weckesser M, Stummer W, Schober O, Winkeler A, Jacobs AH. Specific biomarkers of receptors, pathways of inhibition and targeted therapies: clinical applications. The British Journal of Radiology 2011;84 Spec No 2: S179-95. Abstract

Wagner S, Faust A, Breyholz H-J, Schober O, Schäfers M, Kopka K. The MMP inhibitor (R)-2-(N-benzyl-4-(2-[18F]fluoroethoxy)phenylsulphonamido)-N-hydroxy-3-met hylbutanamide: Improved precursor synthesis and fully automated radiosynthesis. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for use in Agriculture, Industry and Medicine 2011;69: 862-868. Abstract

Wenning C, Stegger D, Hermann S, Schober O, Schäfers M. F-18-FDG Imaging for Atherosclerotic Plaque Characterization. Current Cardiovascular Imaging Reports 2011;4: 190-198. Abstract

Zander T, Scheffler M, Nogova L, Kobe C, Engel-Riedel W, Hellmich M, Papachristou I, Toepelt K, Draube A, Heukamp L, Buettner R, Ko YD, Ullrich RT, Smit E, Boellaard R, Lammertsma AA, Hallek M, Jacobs AH, Schlesinger A, Schulte K, Querings S, Stoelben E, Neumaier B, Thomas RK, Dietlein M, Wolf J. Early prediction of nonprogression in advanced non-small-cell lung cancer treated with erlotinib by using [(18)F]fluorodeoxyglucose and [(18)F]fluorothymidine positron emission tomography. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 2011;29: 1701-1708. Abstract


2010

Büther F, Ernst I, Dawood M, Kraxner P, Schäfers M, Schober O, Schäfers KP. Detection of respiratory tumour motion using intrinsic list mode-driven gating in positron emission tomography. European Journal of Nuclear Medicine and Molecular Imaging 2010;37: 2315-2327. Abstract

Bovens S, Schulze Elfringhoff A, Kaptur M, Reinhardt D, Schäfers M, Lehr M. 1-(5-Carboxyindol-1-yl)propan-2-one Inhibitors of Human Cytosolic Phospholipase A(2)alpha: Effect of Substituents in Position 3 of the Indole Scaffold on Inhibitory Potency, Metabolic Stability, Solubility, and Bioavailability. Journal of Medicinal Chemistry 2010;53: 8298–8308. Abstract

Breyholz HJ, Wagner S, Faust A, Riemann B, Höltke C, Hermann S, Schober O, Schäfers M, Kopka K. Radiofluorinated pyrimidine-2,4,6-triones as molecular probes for noninvasive MMP-targeted imaging. ChemMedChem 2010;5: 777-789. Abstract

Buscher K, Judenhofer MS, Kuhlmann MT, Hermann S, Wehrl HF, Schäfers KP, Schäfers M, Pichler BJ, Stegger L. Isochronous assessment of cardiac metabolism and function in mice using hybrid PET/MRI. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2010;51: 1277-1284. Abstract

Dawood M, Brune C, Büther F, Jiang X, Burger M, Schober O, Schäfers M, Schäfers KP. A continuity equation based optical flow method for cardiac motion correction in 3 D PET data. Proceedings MICCA/MIA 2010;6326: 88-97. Abstract

Dhermain FG, Hau P, Lanfermann H, Jacobs AH, van den Bent MJ. Advanced MRI and PET imaging for assessment of treatment response in patients with gliomas. Lancet Neurology 2010;9: 906-920. Abstract

Drews A, Bovens S, Roebrock K, Sunderkotter C, Reinhardt D, Schäfers M, van der Velde A, Schulze Elfringhoff A, Fabian J, Lehr M. 1-(5-carboxyindol-1-yl)propan-2-one inhibitors of human cytosolic phospholipase A(2)alpha with reduced lipophilicity: synthesis, biological activity, metabolic stability, solubility, bioavailability, and topical in vivo activity. Journal of Medicinal Chemistry 2010;53: 5165-5178. Abstract

Ernst L, Büther F, Dawood M, Moustakis C, Willich N, Schäfers K, Boelling T. Listmode based PET/CT planning for motion detection in high precision radiotherapy. Strahlentherapie und Onkologie 2010;186: 13-14.

Fabritz L, Damke D, Emmerich M, Kaufmann SG, Theis K, Blana A, Fortmuller L, Laakmann S, Hermann S, Aleynichenko E, Steinfurt J, Volkery D, Riemann B, Kirchhefer U, Franz MR, Breithardt G, Carmeliet E, Schäfers M, Maier SKG, Carmeliet P, Kirchhof P. Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3. Cardiovascular Research 2010;87: 60-72. Abstract

Flotats A, Carrio I, Agostini D, Le Guludec D, Marcassa C, Schäfers K, Somsen GA, Unlu M, Verberne HJ. Proposal for standardization of 123I-metaiodobenzylguanidine (MIBG) cardiac sympathetic imaging by the EANM Cardiovascular Committee and the European Council of Nuclear Cardiology. European Journal of Nuclear Medicine and Molecular Imaging 2010;37: 1802-1812. Abstract

Galldiks N, Kracht LW, Burghaus L, Ullrich RT, Backes H, Brunn A, Heiss W-D, Jacobs AH. Patient-tailored, imaging-guided, long-term temozolomide chemotherapy in patients with glioblastoma. Molecular Imaging : Official Journal of the Society for Molecular Imaging 2010;9: 40-46. Abstract

Gigengack F, Ruthotto L, Burger M, Wolters CH, Jiang X, Schäfers K. Motion correction of cardiac PET using mass-preserving registration. Nuclear Science Symposium Conference Record (NSS/MIC), 2010 IEEE 2010: 3317-3319.

Hohmann C, Radziwill R, Klotz JM, Jacobs AH. Health-related quality of life after ischemic stroke: the impact of pharmaceutical interventions on drug therapy (pharmaceutical care concept). Health and Quality of Life Outcomes 2010;8: 59. Abstract

Hugenberg V, Frohlich R, Haufe G. Oxidative desulfurization-fluorination of thioethers Application for the synthesis of fluorinated nitrogen containing building blocks. Organic & Biomolecular Chemistry 2010;8: 5682-5691. Abstract

Hugenberg V, Wagner S, Kopka K, Schober O, Schäfers M, Haufe G. Synthesis of geminal difluorides by oxidative desulfurization-difluorination of alkyl aryl thioethers with halonium electrophiles in the presence of fluorinating reagents and its application for 18F-radiolabeling. The Journal of Organic Chemistry 2010;75: 6086-6095. Abstract

Korb A, Hillmann A, Burgis S, Kollias G, Hermann S, Schäfers M, Pap T, Weide T, Gessner A, Pavenstadt H. The TRAF6 binding molecule p62/SQSTM1 is a critical regulator of inflammatory bone destruction. Annals of the Rheumatic Diseases 2010;69: A19-A19.

Law MP, Schäfers K, Kopka K, Wagner S, Schober O, Schäfers M. Molecular imaging of cardiac sympathetic innervation by 11C-mHED and PET: from man to mouse?. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2010;51: 1269-1276. Abstract

Law MP, Wagner S, Kopka K, Renner C, Pike VW, Schober O, Schäfers M. Preclinical evaluation of an 18F-labelled beta1-adrenoceptor selective radioligand based on ICI 89,406. Nuclear Medicine and Biology 2010;37: 517-526. Abstract

Lindner O, Burchert W, Bengel FM, Zimmermann R, Vom Dahl J, Schäfer W, Schober O, Schäfers M. [Myocardial perfusion scintigraphy 2008 in Germany - results of the fourth query]. Nuklearmedizin. Nuclear Medicine 2010;49: 65-72. Abstract

Lucignani G, Schäfers M. PET, CT and MRI characterisation of the atherosclerotic plaque. European Journal of Nuclear Medicine and Molecular Imaging 2010;37: 2398-2402. Abstract

Range FT, Wenning C, Rahbar K, Schober O Schäfers M. Nuclear medicine imaging of the heart and large vessels - State of the art. Zeitschrift für Herz-, Thorax- und Gefäßchirurgie 2010;24: 169-184. Abstract

Reif PS, Strzelczyk A, Rüegg S, Jacobs AH, Haag A, Hermsen A, Sure U, Knake S, Hamer HM, Strik H, Krämer G, Engenhart-Cabilic R, Rosenow F. [Primary brain tumors and brain metastases Symptomatic epilepsy and driving ability - systematic review and expert opinion]. Der Nervenarzt 2010;81: 1467-1475. Abstract

Reuter S, Schnöckel U, Edemir B, Schröter R, Kentrup D, Pavenstädt H, Schober O, Schlatter E, Gabriels G, Schäfers M. Potential of noninvasive serial assessment of acute renal allograft rejection by 18F-FDG PET to monitor treatment efficiency. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2010;51: 1644-1652. Abstract

Schäfers M, Schober O, Hermann S. Matrix-metalloproteinases as imaging targets for inflammatory activity in atherosclerotic plaques. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2010;51: 663-666. Abstract

Schnöckel U, Hermann S, Stegger L, Law M, Kuhlmann M, Schober O, Schäfers K, Schäfers M. Small-animal PET: a promising, non-invasive tool in pre-clinical research. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2010;74: 50-54. Abstract

Tenbrinck D, Dawood M, Gigengack F, Fieseler M, Xiaoyi Jiang, Schäfers K. Motion correction in Positron Emission Tomography considering Partial Volume Effects in optical flow estimation. Biomedical Imaging: From Nano to Macro, 2010 IEEE International Symposium on 2010: 1233-1236. Abstract

Tiemann K, Stypmann J, Landeta F, Wiebe S, Schäfers M, Schober O, Weckesser M, Rahbar K. Three-dimensional echocardiography and 153Sm-EDTMP SPECT/CT in extensive cardiac metastases from osteosarcoma. European Journal of Nuclear Medicine and Molecular Imaging 2010;37: 2406. Abstract

Tsotsalas MM, Kopka K, Luppi G, Wagner S, Law MP, Schäfers M, De Cola L. Encapsulating (111)In in nanocontainers for scintigraphic imaging: synthesis, characterization, and in vivo biodistribution. ACS nano 2010;4: 342-348. Abstract

Van Camp N, Boisgard R, Kuhnast B, Theze B, Viel T, Gregoire M-C, Chauveau F, Boutin H, Katsifis A, Dolle F, Tavitian B. In vivo imaging of neuroinflammation: a comparative study between [(18)F]PBR111, [ (11)C]CLINME and [ (11)C]PK11195 in an acute rodent model. European Journal of Nuclear Medicine and Molecular Imaging 2010;37: 962-972. Abstract

Waerzeggers Y, Monfared P, Viel T, Winkeler A, Jacobs AH. Mouse models in neurological disorders: applications of non-invasive imaging. Biochimica et Biophysica Acta 2010;1802: 819-839. Abstract

Waerzeggers Y, Rahbar K, Riemann B, Weckesser M, Schäfers M, Hesselmann V, Niederstadt T, Willich N, Stummer W, Paulus W, Schober O, Jacobs AH. PET in the diagnosis and management of patients with brain metastasis: Current role and future perspectives. Cancer Biomarkers : Section A of Disease Markers 2010;7: 219-233. Abstract


2009

Büther F, Dawood M, Stegger L, Wübbeling F, Schäfers M, Schober O, Schäfers KP. List mode-driven cardiac and respiratory gating in PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50: 674-681. Abstract

Cerchia L, Esposito CL, Jacobs AH, Tavitian B, de Franciscis V. Differential SELEX in human glioma cell lines. PloS one 2009;4: e7971. Abstract

Dawood M, Büther F, Schober O, Schäfers M, Schäfers KP. Wieviele respiratorische Gates? Einfluss der Anzahl an Gates auf atemgetriggerte PET Aufnahmen. Nuklearmedizin 2009;48: A23.

Dawood M, Büther F, Stegger L, Jiang X, Schober O, Schäfers M, Schäfers KP. Optimal number of respiratory gates in positron emission tomography: a cardiac patient study. Medical Physics 2009;36: 1775-1784. Abstract

Ernst I, Büther F, Dawood M, Kraxner P, Moustakis C, Bolling T, Schober O, Schäfers K, Willich N. PET/CT for movement detection in high precision radiotherapy. Strahlentherapie und Onkologie 2009;185: 35-36.

Faust A, Hermann S, Wagner S, Haufe G, Schober O, Schäfers M, Kopka K. Molecular imaging of apoptosis in vivo with scintigraphic and optical biomarkers--a status report. Anti-Cancer Agents in Medicinal Chemistry 2009;9: 968-985. Abstract

Faust A, Waschkau B, Waldeck J, Höltke C, Breyholz H-J, Wagner S, Kopka K, Schober O, Heindel W, Schäfers M, Bremer C. Synthesis and evaluation of a novel hydroxamate based fluorescent photoprobe for imaging of matrix metalloproteinases. Bioconjugate Chemistry 2009;20: 904-912. Abstract

Höltke C, Faust A, Breyholz H-J, Kopka K, Schober O, Riemann B, Bremer C, Schäfers M, Wagner S. Non-invasive approaches to visualize the endothelin axis in vivo using state-of-the-art molecular imaging modalities. Mini Reviews in Medicinal Chemistry 2009;9: 1580-1595. Abstract

Höltke C, Law MP, Wagner S, Kopka K, Faust A, Breyholz H-J, Schober O, Bremer C, Riemann B, Schäfers M. PET-compatible endothelin receptor radioligands: synthesis and first in vitro and in vivo studies. Bioorganic & Medicinal Chemistry 2009;17: 7197-7208. Abstract

Höltke C, Waldeck J, Kopka K, Heindel W, Schober O, Schäfers M, Bremer C. Biodistribution of a nonpeptidic fluorescent endothelin A receptor imaging probe. Molecular Imaging : Official Journal of the Society for Molecular Imaging 2009;8: 27-34. Abstract

Hugenberg V, Haufe G. Oxidative Desulfurization-Difluorination of Alkyl Aryl Thioethers: Synthesis of ω-Substituted 1,1-Difluoroalkanes. Synlett 2009: 106-108. Abstract

Kato K, Schober O, Ikeda M, Schäfers M, Ishigaki T, Kies P, Naganawa S, Stegger L. Evaluation and comparison of 11C-choline uptake and calcification in aortic and common carotid arterial walls with combined PET/CT. European Journal of Nuclear Medicine and Molecular Imaging 2009;36: 1622-1628. Abstract

Kopka K, Faust A, Hermann S, Kuhlmann M, Wagner S, Klohs J, Schober O, Wunder A, Schäfers M. 18F-Labeled Isatin as putative biomarker for the specific imaging of activated caspases in apoptosis. Journal of Labelled Compounds & Radiopharmaceuticals 2009;52: S39-S39.

Lindner O, Burchert W, Bengel FM, Zimmermann R, vom Dahl J, Schafer W, Schober O, Schäfers M. [Myocardial perfusion scintigraphy 2007 in Germany--results of the query and current status]. Nuklearmedizin. Nuclear Medicine 2009;48: 131-137. Abstract

Podichetty AK, Faust A, Kopka K, Wagner S, Schober O, Schäfers M, Haufe G. Fluorinated isatin derivatives Part 1: synthesis of new N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatins as potent caspase-3 and -7 inhibitors. Bioorganic & Medicinal Chemistry 2009;17: 2680-2688. Abstract

Podichetty AK, Wagner S, Faust A, Schäfers M, Schober O, Kopka K, Haufe G. Fluorinated isatin derivatives Part 3 New side-chain fluoro-functionalized pyrrolidinyl sulfonyl isatins as potent caspase-3 and -7 inhibitors. Future Medicinal Chemistry 2009;1: 969-989. Abstract

Podichetty AK, Wagner S, Schroer S, Faust A, Schäfers M, Schober O, Kopka K, Haufe G. Fluorinated isatin derivatives Part 2 New N-substituted 5-pyrrolidinylsulfonyl isatins as potential tools for molecular imaging of caspases in apoptosis. Journal of medicinal chemistry 2009;52: 3484-3495. Abstract

Range FT, Paul M, Schäfers KP, Acil T, Kies P, Hermann S, Schober O, Breithardt G, Wichter T, Schäfers MA. Myocardial perfusion in nonischemic dilated cardiomyopathy with and without atrial fibrillation. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2009;50: 390-396. Abstract

Reuter S, Schnöckel U, Schroter R, Schober O, Pavenstädt H, Schäfers M, Gabriels G, Schlatter E. Non-invasive imaging of acute renal allograft rejection in rats using small animal F-FDG-PET. PloS one 2009;4: e5296. Abstract

Reuter S, Schnockel U, Edemir B, Kanzog A, Schroter R, Neugebauer U, Pavenstadt H, Schober O, Schäfers M, Schlatter E, Gabriels G. FDG-Positron Emission Tomography in Diagnosis and Therapy Follow-Up of Acute Rat Renal Allograft Rejection. AMERICAN JOURNAL OF TRANSPLANTATION 2009;9: 554-555.

Ropinski T, Hermann S, Reich R, Schäfers M, Hinrichs K. Multimodal vessel visualization of mouse aorta PET/CT scans. IEEE Transactions on Visualization and Computer Graphics 2009;15: 1515-1522. Abstract

Schäfers M, Bengel F, Bull U, Burchert W, Kies P, Kluge R, Krause BJ, Lindner O, Nienaber C, Nowak B, Schafer W, Schober O, Schwaiger M, Silber S, Vom Dahl J, Zimmermann R. [Position paper nuclear cardiology: update 2008]. Nuklearmedizin. Nuclear Medicine 2009;48: 71-78. Abstract

Stegger L, Heijman E, Schäfers KP, Nicolay K, Schäfers MA, Strijkers GJ. Quantification of left ventricular volumes and ejection fraction in mice using PET, compared with MRI. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2009;50: 132-138. Abstract

Stelljes M, Hermann S, Kohler G, Silling G, Berdel WE, Schober O, Schäfers M, Kienast J. Noninvasive assessment of intestinal graft-versus-host disease activity by molecular imaging with 18F-fluorodeoxyglucose positron emission tomography. Bone Marrow Transplantation 2009;43: S15-S15.

Ullrich RT, Kracht L, Brunn A, Herholz K, Frommolt P, Miletic H, Deckert M, Heiss W-D, Jacobs AH. Methyl-L-11C-methionine PET as a diagnostic marker for malignant progression in patients with glioma. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2009;50: 1962-1968. Abstract

Wagner S, Breyholz H-J, Höltke C, Faust A, Schober O, Schäfers M, Kopka K. A new 18F-labelled derivative of the MMP inhibitor CGS 27023A for PET: radiosynthesis and initial small-animal PET studies. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for use in Agriculture, Industry and Medicine 2009;67: 606-610. Abstract

Wagner S, Breyholz H, Schäfers M, Schober O, Kopka K. 18F-Labeled pyrimidine-2,4,6-triones as potential probes for imaging activated MMPS. Journal of Labelled Compounds & Radiopharmaceuticals 2009;52: S40-S40.

Weberpals M, Hermes M, Hermann S, Kummer MP, Terwel D, Semmler A, Berger M, Schäfers M, Heneka MT. NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits. The Journal of Neuroscience : the Official Journal of the Society for Neuroscience 2009;29: 14177-14184. Abstract


2008

Benning M, Kösters M, Wübbeling F, Schäfers K, Burger M. A nonlinear variational method for improved quantification of myocardial blood flow using dynamic H215O pET. IEEE 2008: 4472-4477.

Dawood M, Kösters T, Fieseler M, Büther F, Jiang X, Schäfers KP. Motion Correction on Dual ECG and Respiratory Gated 0440 3D Cardiac PET/CT Data. lncs 2008: 155-162.

Faust A, Waschkau B, Waldeck J, Höltke C, Breyholz H-J, Wagner S, Kopka K, Heindel W, Schäfers M, Bremer C. Synthesis and evaluation of a novel fluorescent photoprobe for imaging matrix metalloproteinases. Bioconjugate Chemistry 2008;19: 1001-1008. Abstract

Janssens K, Boussemaere M, Wagner S, Kopka K, Denef C. Beta1-adrenoceptors in rat anterior pituitary may be constitutively active Inverse agonism of CGP 20712A on basal 3',5'-cyclic adenosine 5'-monophosphate levels. Endocrinology 2008;149: 2391-2402. Abstract

Kobbert C, Mollmann C, Schäfers M, Hermann S, Baba HA, Hoffmeier A, Breithardt G, Scheld HH, Weissen-Plenz G, Sindermann JR. Transgenic model of cardiac rhabdomyosarcoma formation. The Journal of Thoracic and Cardiovascular Surgery 2008;136: 1178-1186. Abstract

Kopka K, Hermann S, Faust A, Kuhlmann M, Wagner S, Breyholz HJ, Schober O, Schäfers M. Imaging of the "roads to ruin": 18F-labelled isatin as potential tracer for the molecular visualisation of activated caspases in apoptosis. The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutica 2008;52: 21-22.

Law MP, Wagner S, Kopka K, Pike VW, Schober O, Schäfers M. Are [O-methyl-11C]derivatives of ICI 89,406 beta1-adrenoceptor selective radioligands suitable for PET?. European Journal of Nuclear Medicine and Molecular Imaging 2008;35: 174-185. Abstract

Levkau B, Schäfers M, Wohlschlaeger J, von Wnuck Lipinski K, Keul P, Hermann S, Kawaguchi N, Kirchhof P, Fabritz L, Stypmann J, Stegger L, Flogel U, Schrader J, Fischer JW, Hsieh P, Ou YL, Mehrhof F, Tiemann K, Ghanem A, Matus M, Neumann J, Heusch G, Schmid KW, Conway EM, Baba HA. Survivin determines cardiac function by controlling total cardiomyocyte number. Circulation 2008;117: 1583-1593. Abstract

Riemann B, Schäfers KP, Schober O, Schäfers M. Small animal PET in preclinical studies: opportunities and challenges. The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutica 2008;52: 215-221.

Schäfers M. The future of molecular imaging in the clinic needs a clear strategy and a multidisciplinary effort. Basic Research in Cardiology 2008;103: 200-202. Abstract

Schnöckel U, Reuter S, Stegger L, Schlatter E, Schäfers KP, Hermann S, Schober O, Gabriels G, Schäfers M. Dynamic 18F-fluoride small animal PET to noninvasively assess renal function in rats. European Journal of Nuclear Medicine and Molecular Imaging 2008;35: 2267-2274. Abstract

Semmler A, Hermann S, Mormann F, Weberpals M, Paxian SA, Okulla T, Schäfers M, Kummer MP, Klockgether T, Heneka MT. Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism. Journal of Neuroinflammation 2008;5: 38. Abstract

Stegger L, Schäfers M, Weckesser M, Schober O. EANM-ESR white paper on multimodality imaging. European Journal of Nuclear Medicine and Molecular Imaging 2008;35: 677-680. Abstract

Stelljes M, Hermann S, Albring J, Kohler G, Loffler M, Franzius C, Poremba C, Schlosser C, Volkmann S, Opitz C, Bremer C, Kucharzik T, Silling G, Schober O, Berdel WE, Schäfers M, Kienast J. Clinical molecular imaging in intestinal graft-versus-host disease: mapping of disease activity, prediction, and monitoring of treatment efficiency by positron emission tomography. Blood 2008;111: 2909-2918. Abstract

Waldeck J, Hager F, Höltke C, Lanckohr C, von Wallbrunn A, Torsello G, Heindel W, Theilmeier G, Schäfers M, Bremer C. Fluorescence reflectance imaging of macrophage-rich atherosclerotic plaques using an alphavbeta3 integrin-targeted fluorochrome. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 2008;49: 1845-1851. Abstract


2007

Dawood M, Fieseler M, Büther F, Jiang X, Schäfers KP. A Multi-resolution Optical Flow Based Approach to Respiratory Motion Correction in 3D PET/CT Images. Lecture Notes in Computer Science 2007: 314-322. Abstract

Kummer C, Winkeler A, Dittmar C, Bauer B, Rueger MA, Rueckriem B, Heneka MT, Vollmar S, Wienhard K, Fraefel C, Heiss W-D, Jacobs AH. Multitracer positron emission tomographic imaging of exogenous gene expression mediated by a universal herpes simplex virus 1 amplicon vector. Molecular Imaging 2007;6: 181-192. Abstract

Miletic H, Fischer Y, Litwak S, Giroglou T, Waerzeggers Y, Winkeler A, Li H, Himmelreich U, Lange C, Stenzel W, Deckert M, Neumann H, Jacobs AH, von Laer D. Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene. Molecular Therapy : the Journal of the American Society of Gene Therapy 2007;15: 1373-1381. Abstract

Rueger MA, Kracht LW, Hilker R, Thiel A, Sobesky J, Winkeler A, Thomas AV, Heneka MT, Graf R, Herholz K, Heiss WD, Jacobs AH. Role of in vivo imaging of the central nervous system for developing novel drugs. The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutica 2007;51: 164-181. Abstract

Saydam O, Saydam N, Glauser DL, Pruschy M, Dinh-Van V, Hilbe M, Jacobs AH, Ackermann M, Fraefel C. HSV-1 amplicon-mediated post-transcriptional inhibition of Rad51 sensitizes human glioma cells to ionizing radiation. Gene Therapy 2007;14: 1143-1151. Abstract

Wagner S, Breyholz H-J, Law MP, Faust A, Höltke C, Schroer S, Haufe G, Levkau B, Schober O, Schäfers M, Kopka K. Novel fluorinated derivatives of the broad-spectrum MMP inhibitors N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](benzyl)- and (3-picolyl)-amino]-3-methyl-butanamide as potential tools for the molecular imaging of activated MMPs with PET. Journal of Medicinal Chemistry 2007;50: 5752-5764. Abstract

Winkeler A, Sena-Esteves M, Paulis LEM, Li H, Waerzeggers Y, Ruckriem B, Himmelreich U, Klein M, Monfared P, Rueger MA, Heneka M, Vollmar S, Hoehn M, Fraefel C, Graf R, Wienhard K, Heiss WD, Jacobs AH. Switching on the lights for gene therapy. PloS one 2007;2: e528. Abstract


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