recent Publications
(since 2000)
2000, 2001, 2002, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2016
| 2000 | |
| 86. | Roshan, A., Jabeen, R., Zia-ul-Haq, Akhtar, H., Duddeck, H., Verspohl, E.J. Chiral aryl sulfonyl hydantoins as hypoglycemic agents Zeitschrift für Naturforschung 55b, 203-207, 2000 |
| 87. | Bozdag, O, Verspohl, E.J., Ertan, R. Synthesis and hypoglycemic activity of some new flavone derivatives II (4'-Flavonyl-2,4-thiazolidinediones) Arzneimittelforschung/Drug Res. 50, 539-543, 2000 |
| 88. | Bozdag, O, Verspohl, E.J., Ertan, R. Synthesis and hypoglycemic activity of some new flavone derivatives III (3'-Flavonyl-2,4-thiazolidinediones) 3rd Communication Arzneimittelforschung/Drug Res. 50, 626-630, 2000 |
| 89. | Verspohl, E.J., LaMura M. Biological effects of newly synthesized cholecystokinin receptor agonists Hormone Research 53, 177-184, 2000 |
| 2001 | |
| 90. | Blumentrath, J., Neye, H., Verspohl, E.J. Effects of retinoids and thiazolidinediones on proliferation, insulin release, and -insulin mRNA and GLUT 2 transporter mRNA of INS1 cells Cell Biochem Funct 19: 159-169, 2001 |
| 91. | Verspohl, E.J. Risikofaktor Hyperglykämie, Langzeitkomplikationen schlecht eingestellter Diabetiker Pharm i u Zeit 30 (2), 2-10, 2001 |
| 92. | Neye, H., Verspohl, E.J. Problemorientiertes Lernen im Pharmaziestudium Pharm. Ztg. 146(25), 2112-2116, 2001 |
| 93. | Böcker, D., Verspohl, E.J. Role of protein kinase C, PI3-Kinase and tyrosine kinase in activation of MAP kinase by glucose and agonists of G-protein coupled receptors in INS-1 cells Int. J. Exper. Diabetes Res. 2, 233-244, 2001 |
| 2002 | |
| 94. | Verspohl, E.J. Wechselwirkungen von Arzneimitteln mit Nahrungsmitteln Zeitschr. für Allgemeinmedizin 6-7, 275-283, 2002 |
| 95. | Verspohl, E.J. Recommended testing in diabetes research Planta Med. 68, 581-590, 2002 |
| 96. | Verspohl, E.J., Johannwille, B., Waheed, A., Neye, H. Effect of purinergic agonists and antagonists on insulin secretion of INS-1 cells (insulinoma cell line) and rat pancreatic islets Can. J. Physiology and Pharmacology 80: 562-568, 2002 |
| 97. | Verspohl, E.J. Gene therapy - the method of the future for causal treatment of diabetes? Pharm i u Zeit 31, 238-241, 2002 |
| 98. | Verspohl, E.J., Weiland, F. Against insulin resistance. Insulin sensitizers Pharm i u Zeit 31, 280-292, 2002 |
| 99. | Verspohl, E.J. Weight reduction. Antiobesity drug treatment in type-2 diabetics Pharm i u Zeit 31, 300-307, 2002 |
| 100. | Verspohl, E.J. What are the costs of type-2 diabetes? Pharmacoeconomics Pharm i u Zeit 31, 308-311, 2002 |
| 2003 | |
| 101. | Tuncbilek, M., Bozdag-Dündar, O, Ayhan-Kilcigil, G., Waheed, A. Verspohl, E.J., Ertan, R. Synthesis and hypoglycemic activity of some substituted flavonyl thiazolidinedione derivatives: 5th communication: flavonyl benzyl substituted 2,4-thiazolidiones Farmaco 58 (1): 83, 2003 |
| 102. | Verspohl, E.J., Blackburn, M.G., Hohmeier, N., Hagemann, J., Lempka, M. Synthetic non-degradable diadenosine polyphosphates and diinosine polyphosphates: their effects on INS-1 (insulin secreting cells) and VSMC (cultured vascular smooth muscle cells) J Med Chem 46, 1554-1562, 2003 |
| 103. | Feldkämper I, Verspohl EJ, Neye H The Serpins Alpha-1-Antitrypsin and Alpha-1-Antichymotrypsin Specifically interact with Immunophilins Die Pharmazie 58, 811-816, 2003 |
| 104. | Verspohl, E.J., Schlüter, H., Zidek, W. Long-term effects of diadenosine polyphosphates on blood pressure, heart rate, glucose and insulin levels of rats Medicinal Chemistry Research 11:8, 445-462, 2003 |
| 105. | Verspohl EJ, Hohmeier N, Lempka M Diadenosine tetraphosphate (Ap4A) induces a diabetogenic situation: its impact on blood glucose, plasma insulin, gluconeogenesis, glucose uptake and GLUT-4 transporter Die Pharmazie 58, 910-915, 2003 |
| 106. | Bozdag-Dündar, O, Verspohl, E.J., Waheed, A., Ertan, R. Synthesis and antidiabetic activity of some new furochromyl-2,4,-thiazolidinediones Arzneimittelforschung/Drug Res. 53, 831-836, 2003 |
| 2004 | |
| 107. | Zakir Hussain, Abdul Waheed, Rizwana Aleem Qureshi, Dadu Khan Burdi, Eugen J. Verspohl, Naeema Khan, and Mashooda Hasan The effect of medicinal plants of islamabad and murree region of Pakistan on insulin secretion from INS-1 cells. Phytother Res. 18: 73-77, 2004 |
| 108. | Verspohl E.J., Hagemann J, Lempka M Vascular smooth muscle cells (VSMC) proliferation of streptozotocin-diabetic animals induced by diadenosine polyphosphates Exper Clin Endocrinology Diabetes 112: 142-147, 2004 |
| 109. | D. Rüsing, E.J. Verspohl Influence of diadenosine tetraphosphate on lipid metabolism Cell Biochem Funct 22: 1-6, 2004 |
| 110. | Adebajo, A.C., Olyiwola G, Verspohl, E.J., Iwalewa EO, Omisore NOA, Bergenthal D, Kumar V., Adesina S.K. Evaluation of the ethnomedical claims of Murraya koenigii Pharmaceutical Biology 42: 610-620, 2004 |
| 111. | Rucha J., Verspohl, E.J. Heterologous desensitisation of insulin secretion by GIP (glucose-dependent insulinotropic peptide) in INS-1 cells: the significance of Gai2 and investigations on the mechanism involved Cell Biochem Funct 22: 1-8, 2004 |
| 112. | Verspohl E.J., Engfer A Arzneimittel-Interaktionen bei der Antiparkinson Therapie (Review) Nervenheilkunde 23: 151-159, 2004 |
| 113. | Rüsing D, Verspohl E.J. Eine kritische Bewertung der Abmagerungsmittel (Arzneimittel und Medizinprodukte) MedMoPharm 27: 84- 91: 2004 |
| 114. | Reichmann H, Engfer A, Jost W, Sommer U, Verspohl EJ Parkinson-Datenbank.de Thieme-Verlag, Firma Schering 2004 |
| 115. | Neye, H., Verspohl, E.J. The FK506 Binding Protein 13 kDa (FKBP13) interacts with the C-Chain of Complement C1q BMC Pharmacol 4: 19 (2004) |
| 2005 | |
| 116. | Verspohl E.J., Bauer K., Neddermann E. Antidiabetic effect of Cinnamomum cassia and Cinnamomum zeylanicum in vivo and in vitro Phytotherapy Research 19: 203-206, 2005 |
| 117. | Verspohl E.J. Zukünftige Entwicklungen und neue Hoffnungen für die Therapie des Typ 1 – und Typ 2 Diabetes ? Med Monatsschr Pharmazeuten 28: 193-203, 2005 |
| 118. | Abdel-Aziz H., Nahrstedt A., Petereit F., Windeck T., Verspohl, E.J. 5-HT3 receptor blocking activity of arylalkanes isolated from the rhizoma of Zingiber officinalis Planta Medica 71: 609-616, 2005 |
| 2006 | |
| 119. | Verspohl E.J. Insulin analogues – which dimension should be discussed? Med Monatsschr Pharmaz 29, 198-199, 2006 |
| 120. | Verspohl E.J. Fatty tissue, the largest endocrine organ in the body Pharmazeut. Ztg. 151(29), 16-25, 2006 |
| 121. | Abdel-Aziz H., Windeck T., Ploch M., Verspohl E.J. Mode of action of gingerols and shogaol on 5-HT3 receptors: binding studies, cation uptake by the receptor channel and ilium contraction Eur J Pharmacol 530: 136-143, 2006 |
| 122. | Verspohl E.J. Effect of PAO (phenylarsine oxide) on the negative feedback of insulin and IGF-1 on insulin release from INS-1 cells. Endocrine Journal 53: 21-26, 2006 |
| 123. | Bertarelli D.C.G., Diekmann M., Hayallah A.M., Rüsing D., Iqbal J., Preiss B., Verspohl E.J., Müller C.E. Characterisation of human and rodent native and recombinant A2B adenosine receptors by radioligand binding studies Purinergic Signaling 2: 559-571, 2006 |
| 124. | Adebajo A. C., Olayiwola G., Verspohl J.E., Iwalewa E.O., Omisore N.O.A., Bergenthal D., Kumar V. and Adesina S.K. Evaluation of the ethnomedical claims of Murraya koenigii. Pharmaceutical Biology 42, 610–620, 2006 |
| 125. | Rüsing D, Müller CE, Verspohl EJ The impact of adenosine and A2B receptors for glucose homeostasis J Pharmacy Pharmacology 58: 1639-1645 (2006) |
| 2007 | |
| 126. | A. C. Adebajo, E. O. Olawode, O. R. Omobuwajo, F. Begrow, A. Elkhawad, S. A. Adesanya, M. A. Akanmu, R. Edrada, P. Proksch, T. J. Schmidt, M. Klaes and E. J. Verspohl. Hypoglycemic constituents of Stachytarpheta cayennensis leaf Planta Medica 73, 241-250 (2007) |
| 127. | Fleer H, Verspohl EJ Antispasmodic activity of an extract from Plantago lanceolata L. and some isolated compounds Phytomedicine 14, 409-415 (2007) |
| 128. | Riyazi A, Hensel A, Geißler N, Schaaf S Verspohl EJ The effect of the volatile oil from Ginger rhizomes (Zingiber officinale Roscoe), its fractions and isolated compounds on the 5-HT3 receptor complex and the serotoninergic system of the rat ileum Planta Medica 73, (2007) |
| 129. | Bozdag-Dündar, O, Ceylan-Ünlüsoy, M, Verspohl, E.J., Ertan, R. Synthesis and antidiabetic activity of some new chromonyl-2,4-thiazolidinediones Arzneimittelforschung/Drug Res 57, 532-536, 2007 |
| 130. | Wittschier N, Lengsfeld C, Vorthems S, Stratmann U, Ernst J, Verspohl EJ, Hensel A Large Molecules as antiadhesive compounds against pathogens. J Pharm Pharmacol 59, 777-786, 2007 |
| 131. | Wienkötter N , Begrow F, Kinzinger U, Schierstedt D, Verspohl EJ The effect of thyme extract on β2-receptors and mucociliary clearance Planta Medica 73: 629-635, 2007 |
| 2008 | |
| 132. | Wienkötter N, Höpner D, Schütte U, Bauer K, Begrow F, El-Dakhakhny M, Verspohl EJ The effect of nigellone and thymoquinone on trachea relaxation and mucociliary clearance Planta Medica 74, 105-108 (2008) |
| 133. | Verspohl EJ Das viszerale Fettgewebe – Basis für chronisch entzündliche Erkrankungen Schweiz. Zeitschrift für Ernährungsmedizin 6 (1), 11-15, 2008 |
| 134. | K. Bauer, A. Biller, E.J. Verspohl Untersuchung von Bestandteilen eines pflanzlichen Antidiarrhoikums auf spasmolytische Effekte Zeitschrift für Phytotherapie 29 (2008) |
| 135. | Bozdağ-Dündar O, Mentese A, Verspohl EJ Synthesis and antidiabetic activity of some new thiazolyl-2,4-thiazolidinediones Arzneimittelforschung/Drug Research 58, 131-135, 2008 |
| 136. | Verspohl EJ, Ploch M, Windeck T, Klaes M, Schmidt T, Bauer K Effect of two artichocke extracts (36_U and 36_EB) on rat ileum (with respect to bowel syndrome) and the peristaltic threshold Phytomedicine (ahead of publication Apr 2008) |
| 137. | Weiland F, Verspohl EJ Variety of angiotensin receptors in 3T3-L1 preadipose cells and differentiated adipocytes Horm Metab Res 40, 760-766 (2008) |
| 138. | Töpfer M, Müller CE, Knittel J, Verspohl EJ Modulation of insulin release by adenosine A1 receptor agonists and antagonists in INS-1 cells: the possible contribution of 86Rb+ efflux and 45Ca2+ uptake. Cell Biochemistry and Function 26: 833-843 (2008) |
| 139. | Bozdağ-Dündar O, Verspohl EJ, Das-Evcimen N, Kaup RM, Bauer K, Evranos B, Ertan R Synthesis and hypoglycemic activity of some new flavonyl-2,4-thiazolidinediones Bioorganic and Medicinal Chemistry 16: 6747-6751 (2008) |
| 140. | Engelbertz J, Schwenk T, Kinzinger U, Schierstedt D, Verspohl EJ Thyme Extract, but not Thymol, Inhibits Endothelin-Induced Contractions of Isolated Rat Trachea Planta Medica 74: 1436-1440 (2008) |
| 2009 | |
| 141. | Adebajo AC, Iwalewa EO, Obuotor EM, Ibikunle GF, Omisore NO, Adewunmi CO, Obaparusi OO, Klaes M. Schmidt, T, Verspohl EJ. Anti-trichomonal and Antidiabetic Activities of the Extracts and Isolates of Clausena lansium J stem bark. J. Ethnopharmacology 122, 10-19 (2009) |
| 142. | Qa'dan F, Verspohl EJ, Nahrstedt A, Petereit F, Matalka KZ Cinchonain Ib isolated from Eriobotrya japonica induces insulin secretion in vitro and in vivo J Ethnopharmacology 124: 224-227 (2009) |
| 143. | Verspohl EJ Novel therapeutics for type 2 diabetes: incretin hormone mimetics (glucagon-like peptide-1 receptor agonists) and dipeptidyl peptidase-4 inhibitors Pharmacology and Therapeutics 124, 113-138 (2009) |
| 144. | Begrow F, Engelbertz J, Feistel B, Lehnfeld R, Bauer K, Verspohl EJ Impact of thymol in thyme extracts on their antispasmodic action and ciliary clearance Planta Medica 75: 1-8 (2009) |
| 145. | Weiland F, Verspohl EJ Local formation by adipocytes of angiotensin peptides with paracrine activity J Peptide Science 15: 767-776 (2009) |
| 146. | Heimes K, Feistel B, Verspohl EJ Impact of the 5-HT3 receptor channel system for insulin secretion and interaction of ginger extracts Eur J Pharmacol 624, 58-65, 2009 |
| 2010 | |
| 147. | Begrow F, Engelbertz J, Feistel B, Lehnfeld R, Bauer K, Verspohl EJ Impact of thymol in thyme extracts on their antispasmodic action and ciliary clearance Planta Medica 76: 311-318 (2010) |
| 148. | Verspohl EJ Typ 2 Diabetes: Inkretinhormone als neue Targets Pharmazeut. Zeitung 155: 20-27 (2010) (Review) |
| 149. | Enzensperger C, Lehmann J, von Schroetter K, Riyazi A, Verspohl EJ Arylalkylamine-, beta-carboline-, quinolizine- and azecine-derived compounds and their in vitro interaction with the ionotropic 5-HT3 receptor: search for new lead structures. Arzneimittelforsch/Drug Res 60: 544-552 (2010) |
| 150. | Ceylan-Ünlüsoy M, Verspohl EJ, Ertan R Synthesis and Antidiabetic activity of some new chromonyl-2,4-Thiazolidinediones J Enzyme Inhib Med Chem 25: 784-789 (2010) |
| 151. | Siebelmann M, Wensing J, Verspohl EJ The impact of ANGII and IV on INS-1 cells and on blood glucose and plasma insulin J Recept Signal Transduct Res 30: 234-245 (2010) |
| 2011 | |
| 152. | Heimes K, Hauk F, Verspohl EJ. Mode of action of peppermint oil and (-)-menthol with respect to 5-HT3 receptors (serotonin receptor subtype): binding studies, cation uptake by the receptor channel and contraction of isolated rat ileum Phytother Res. 25: 702-708 (2011) |
| 153. | Butterweck V, Semlin L, Feistel B, Pischel I, Bauer K, Verspohl EJ Comparative evaluation of two Opuntia ficus indica extracts for blood sugar lowering effects in rats Phytother Res 25: 370-375 (2011) |
| 154. | Alade GO, Omobuwajo OR, Adebajo CA, Verspohl EJ Evaluation of the hypoglycaemic activity of Bauhinia monandra leaf in Alloxan-dibetic rats and INS-1 insulin cells J Chem Pharm Res 3: 506-521 (2011) |
| 2012 | |
| 155. | Podlogar JA, Verspohl EJ Antiinflammatory effects of ginger and its components in BEAS-2B cells (human bronchial epithel cells) Phytotherapy Research 26: 333-336 (2012) |
| 156. | Ezer M, Yildirim LT, Bayro O, Verspohl EJ, Bozdag-Dündar O Synthesis and antidiabetic activity of morpholinothiazolyl-2,4-thiazolidindione derivatives J Enzyme Inhib Med Chem 27: 419-427 (2012) |
| 157. | Böckenholt C, Begrow F, Verspohl EJ Effect of silymarin and harpagoside on inflammation reaktion of BEAS-2B cells, on ciliary beat frequency (CBF) of trachea explants and on mucociliary clearance (MCC) Planta Medica 78: 1-6 (2012) |
| 158. | Verspohl EJ Novel pharmacological approaches to the treatment of type 2 diabetes Pharmacol Rev 64: 188-237 (2012) |
| 159. | Podlogar J, Verspohl EJ LPS-induced proliferation and chemokine secretion from BEAS-2B cells Pharmacology & Pharmacy 3: 166-177 (2012) |
| 160. | Engelbertz J, Lechtenberg M, Studt L, Hensel A, Verspohl EJ Bioassay-guided fractionation of a thymol-deprived hydrophilic thyme extract and its antispasmodic effect J Ethnopharmacol 141: 848-853 (2012) |
| 161. | Ceylan-Ünlüsoy M, Kazak C, Bayro O, Verspohl EJ, Ertan R, Bozdag-Dündar O Synthesis and antidiabetic activity of 2,4-thiazolidindione, imidazolinedione and 2-thioxo-imidazoline-4-one derivatives bearing 6-methyl chromonyl pharmacophore J Enzyme Inhib Med Chem. 2012 Oct 12. [Epub ahead of print] |
| 162. | Alade GO, Adebajo CA, Omobuwajo OR, Proksch P, Verspohl EJ Quercetin, a minor constituent of the anti-hyperglycemic fraction of Bauhinia monandra leaf J Diabetes 4: 439-441 (2012) |
| 163. | Adebajo AC, Odediran OA, Aladesanmi AJ, Iwalewa EO, Olugbade TA, Nneji CM, Ademowo OG, Schmidt TJ, Verspohl EJ Evaluation of Ethnomedical claims: Antihyperglycemic activities of Gongronema latifolium Root and Stem Journal of Diabetes (in press 2012) |
| 164. | Galal O, Podlogar J, Verspohl EJ Impact of ADMA (asymmetric dimethylarginine) on physiology with respect to diabets mellitus and respiratory system and BEAS-2B cells (human bronchial epithelial cells) J Pharmacy Pharmacol (Article first published online: 25 SEP 2012; DOI: 10.1111/j.2042-7158.2012.01590.x) |
| 165. | Kaup R, Khayyal MT, Verspohl EJ Antidiabetic Effects of a standardized Egyptian Rice Bran Extract Phytother Res. 2012 May 8. doi: 10.1002/ptr.4705. [Epub ahead of print] |
| 166. | Begrow F, Böckenholt C, Ehmen M, Wittig T, Verspohl EJ Effect of Myrtol standardized and other substances on respiratory tract: ciliary beat frequency and mucociliary clearance as parameters. Adv Ther 29: 350-358 (2012) |
| 167. | Walaschewski R, Begrow F, Verspohl EJ Impact and benefit of A2B-adenosine receptor agonists for the respiratory tract: mucociliary clearance, ciliary beat frequency, trachea muscle tonus and cytokine release J Pharmacy Pharmacol 65: 123-132 (2012) |
| 2013 | |
| 168. | Verspohl EJ, Fujii H, Homma K, Buchwald-Werner S Testing of AUC-P and AUC-V for their antispasmodic effect Phytomedicine 20: 427-431 (2013) |
| 169. | Begrow F, Verspohl EJ Effect of Ap4A, UTP and Salbutamol on mucociliary clearance in a mouse model of cystic fibrosis Pharmacology & Pharmacy 4: 176-181 (2013) |
| 170. | van Oppen J, Verspohl EJ Effect of Bisphenol-A (BPA) and free fatty acids (FFA) on TH2-cytokine secretion from INS-1 cells Pharmacology & Pharmacy 4: 451-469, 2013 |
| 171. | Adebajo AC, Ayoola MD, Abagbemi OR, Obuotor EM, Ogunsina MO, Verspohl EJ Antihyperglycaemic and anti-oxidant activities of Eugenia uniflora leaf: Evaluation of ethnomedical claims IV. J Diabetes (in press 2013) |
| 172. | Adebajo AC, Odediran SA, Nneji CM, Iwalewa EO, Rukunga GM, Aladesanmi AJ, Gathirwa JW, Ademowo OG, Olugbade TA, Schmidt TJ, Verspohl EJ Evaluation of Ethnomedical Claims II. Antimalarial activities of Gongronema latifolium root and stem. Journal of Herbs, Spices and Medicinal Plants 19: 97-118, 2013 |
| 2014 | |
| 173. | Falck E, Begrow F, Verspohl EJ, Wünsch, B Metabolism studies of ifenprodil, a potent GluN2B receptor antagonist. J Pharmaceut Biomedic Analysis 88: 96-105, 2014 |
| 174. | Falck E, Begrow F, Verspohl EJ, Wünsch, B In vitro and in vivo biotransformation of WMS-1410, a potent GluN2B selective NMDA receptor antagonist. J Pharmaceut Biomedic Analysis 94: 36-44, 2014 |
| 2016 | |
| 175. | Verspohl EJ Neue Targets in der Pharmakotherapie des Typ-2-Diabetes MedMoPharm 39: 50-57, 2016 |