Dr. Matthias Letzel
M-letzel 160x213
Dr. Matthias Letzel
Chemiker, Leiter der Massenspektrometrie
Raum 252b
Tel.: +49 0251 83 33 299
Fax: +49 0251 83 39 772
at uni-muenster.de
Curriculum Vitae
10/89 - 12/91 Chemiestudium in Münster.
Diplomarbeit (H. J. Schäfer) „Auxiliarkontrollierte Dimerisierung von 2-tert.-Butylmalonsäureamid- zu 2,3-Di-tert.-butylbernsteinsäurederivaten durch Kolbe-Elektrolyse“
10/94 - 02/98 Promotionsarbeit (H. J. Schäfer) „Studien zur diastereselektiven Kupplung anodisch erzeugter Radikale in Hetero- und Homokupplungen“
05/98 - 06/99 Postdoctoral Studies (Biologische Massenspektrometrie): Prof. Dr. J. Peter-Katalinic (Inst. f. Medizinische Physik und Biophysik); Centro Internationale di Servizi di Spettrometria di Massa (CISeSMa, Neapel, Consiglio Nationale delle Ricerche); Prof. Dr. Peter (Institut für Organische Chemie und Strukturanalytik der Universität Potsdam)
07/99 - 12/11 Leiter der Massenspektrometrie (Universität Bielefeld, Fakultät für Chemie)
01/12 - 07/12 Stellv. Leiter der Massenspektrometrie am Organisch-Chemischen Institut der Westf. Wilhelms-Universität Münster
since 08/12 Leiter der Massenspektrometrie am Organisch-Chemischen Institut der Westf. Wilhelms-Universität Münster

D. Kuck, S. Heitkamp, J. Sproß, M. C. Letze, I. Ahmed, K. Krohn, R. G. Parker, Y. Wang, V. J. Robbins, W. M. Ames, P. D. Schettler, R. R. Hark
Consecutive losses of two benzyl radicals from the [M +Na]+ adduct ions of di- and tri(benzyloxy)benzenes under ESI/CID conditions
Int. J. Mass Spec. 2015, 377, 23–38.

A. Pirkl, M. Meier, Y. Popkova, M. Letzel, A. Schnapp, J. Schiller, K. Dreisewerd
Analysis of Free Fatty Acids by Ultraviolet Laser Desorption Ionization Mass Spectrometry Using Insect Wings as Hydrophobic Sample Substrates
Anal. Chem. 2014, 86, 10763-10771; dx.doi.org/10.1021/ac5020047.

T. Holtrichter-Rößmann, J. Isermann, C. Rösener, B. Cramer, C.-G. Daniliuc, J. Kösters, M. Letzel, E.-U. Würthwein, W. Uhl
An Aluminum-Nitrogen Based Lewis Pair as an Effective Catalyst for the Oligomerization of Cyanamides: Formation of Acyclic C-N Oligomers Instead of Thermodynamically Favored Cyclic Aromatic Trimers
Angew. Chem. Int. Ed. 2013, 52, 7135–7138.

D. Kuck, L. C. Salameh, K. I. Onwuka, M. C. Letzel
Unidirectional triple hydrogen rearrangement in the radical cations of electron-rich 3-aryl-1-propanols: further evidence and limitation
Eur. J. Mass Spectrom. 2013, 19, in press. doi: 10.1255/ejms.1239

M. Letzel, D. Barth, D. Kuck, H.-F. Grützmacher, S. Y. Kim, M. K. Yim, J. C. Choe
Unimolecular reactions of gaseous picoline radical cations. A new experimental and computational study
Int. J. Mass Spectrom. 2013, 336, 1-16.

A. W. Amick, E. Hoegg, S. Harrison, K. R. Houston, R. R. Hark, I. D. Reingold, D. Barth, M. C. Letzel, D. Kuck
Site-specific hydrogen exchange and hydrogen transfer processes preceding the fragmentation of long-lived radical cations of ethyl dihydrocinnamate and related arylalkanoates
Int. J. Mass Spectrom. 2012, 316-318, 206-215.

C. Fraschetti, M. C. Letzel, A. Filippi, M. Speranza and J. Mattay
Enantioselective supramolecular devices in the gas phase - Resorcin[4]arene as a model system
Beilstein J. Org. Chem. 2012, 8, 539–550.

C. Fraschetti, M. C. Letzel, M. Paletta, J. Mattay, M. Speranz, A. Filippi, M. Aschic and A. B. Rozhenko
Cyclochiral resorcin[4]arenes as effective enantioselectors in the gas phase
J. Mass. Spectrom. 2012, 47, 72–79.

B. Botta, C. Fraschetti, I. D'Acquarica, F. Sacco, J. Mattay, M. C. Letzel, M. Speranza
Unprecedented Gas-Phase Chiroselective Logic Gates
Org. Biomol. Chem. 2011, 9, 1717-1719.

D. Kuck, C. Matthias, D. Barth, M. C. Letzel
Isomerization of the Constituents of Ion/Neutral Complexes During the Fragmentation of Protonated Dialkyl-substituted 1,3-Diphenylpropanes
Int. J. Mass Spectrom. 2011, 306, 167-174.

D. Kuck, H.-F. Grützmacher, D. Barth, S. Heitkamp, M. C. Letzel
The Role of Ion/Neutral Complexes in the Fragmentation of N-Benzyl-(alkylpyridinium) Ions
Int. J. Mass Spectrom. 2010, 306, 159-166.

K. Krohn, I. Ahmed, M. John, M. C. Letzel, D. Kuck
Stereoselective Synthesis of Benzylated Prodelphinidins and Their Diastereomers with Use of the Mitsunobu Reaction in the Preparation of Their Gallocatechin Precursors
Eur. J. Org. Chem. 2010, 2544-2554.

Sebastian Böcker, Matthias Letzel, Zsuzsanna Lipták, Anton Pervukhin
SIRIUS: Decomposing isotope patterns for metabolite identification.
Bioinformatics 2009, 25(2), 218-224.

Maurizio Speranza, Caterina Fraschetti, Ilaria D'Acquarica, Bruno Botta, Francesca Novara, Jochen Mattay, and Matthias Letzel
Gas-phase enantioselectivity of chiral N-linked peptidoresorc[4]arene isomers towards dipeptides
J. Phys. Chem. A 2009, 113, 14625-14629.

Caterina Fraschetti, Francesca R. Novara, Andrea Tafi, Fabiola Sacco, Luisa Mannina, Anatoli P. Sobolev, Jochen Mattay, Matthias C. Letzel, Bruno Botta, and Maurizio Speranza
Interactions of Vinca Alkaloid Subunits with Chiral Amido[4]resorcinarenes: A Dynamic, Kinetic, and Spectroscopic Study.
Org. Biomol. Chem. 2009, 7, 1798-1806.

O. Sekiguchi, V. Meyer, M. C. Letzel, D. Kuck, E. Uggerud
Energetics and reaction mechanisms for the competitive losses of H2, CH4 and C2H4 from protonated methylbenzenes — Implications to the methanol-to-hydrocarbons (MTH) process
Eur. J. Mass Spectrom. 2009, 15, 167-181.

Matthias C. Letzel, Christian Schäfer, Francesca R. Novara, Maurizio Speranza, Alexander B. Rozhenko, Wolfgang W. Schoeller, and Jochen Mattay
Kinetic Study of Guest Displacement Reactions on a Host-Guest Complex with a Photoswitchable Calixarene
J. Mass Spectrometry 2008, 43, 1553-1564.

Tobias Schröder, Ralf Brodbeck, Matthias C. Letzel, Andreas Mix, Björn Schnatwinkel, Markus Tonigold, Dirk Volkmer, Jochen Mattay
A self-assembling metallosupramolecular cage based on cavitand-terpyridine subunits
Tetrahedron Lett. 2008, 49, 5939-5942.

Matthias Letzel, Hans-Friedrich Grützmacher, Daniel Stein and Hansjörg Grützmacher
Trends in the reactions of gaseous phenyl pnictogen radical cations C6H5EH2+ (E = N, P, As)
Dalton Transactions 2008, 25, 3249–3364.

John O. Igoli, Samuel O. Onyiriuka, Matthias C. Letzel, Martin N. Nwaji and Alexander I. Gray
Cassane diterpenoids from Lonchocarpus laxiflorus
Nat. Prod. Commun. 2008, 3, 5-10.

Bruno Botta, Ilaria D'Acquarica, Laura Nevola, Fabiola Sacco, Zara Valbuena Lopez, Giovanni Zappia, Caterina Fraschetti, Maurizio Speranza, Andrea Tafi, Fabiana Caporuscio, Matthias C. Letzel, and Jochen Mattay
Bis(diamido)-bridged basket resorc[4]arenes: as enantioselective receptors for amino acids and amines
Eur. J. Org. Chem. 2007, 36, 5995-6002.

Sebastian Böcker, Matthias Letzel, Zsuzsanna Lipták, Anton Pervukhin
Decomposing metabolomic isotope patterns.
Proc. of the 6th Workshop on Algorithms in Bioinformatics (WABI 2006), LNBI/LNCS 4175: 12-23 ( 2006).

Stian Svelle, Morten Bjørgen, Stein Kolboe, Dietmar Kuck, Matthias Letzel, Unni Olsbye, Osamu Sekiguchi and Einar Uggerud
Intermediates in the methanol-to-hydrocarbons (MTH) reaction: a gas phase study of the unimolecular reactivity of multiply methylated benzenium cations
Catal. Lett. 2006, 109, 25-35.

M. Letzel, D. Kirchhoff, H.F. Grützmacher, D. Stein, H. Grützmacher
Isomerization and fragmentation reactions of gaseous phenylarsane radical cations and phenylarsanyl cations. A study by tandem mass spectrometry and theoretical calculations
Dalton Trans. 2006, 16, 2008-2016.

Alexander B. Rozhenko, Wolfgang W. Schoeller, Matthias C. Letzel, Björn Decker, Ceno Agena, Jochen Mattay
Calixarenes as Hosts for Ammonium Cations: A Quantumchemical Study with Mass-Spectrometric Investigations
Chem. Eur. J. 2006, 12, 8995-9000.

Christian Schäfer, Björn Decker, Matthias Letzel, Francesca Novara, Rainer Eckel, Robert Ros, Dario Anselmetti, Jochen Mattay
On the Way to Supramolecular Photochemistry at the Single Molecule Level
Pure Appl. Chem. 2006, 78, 2247-2259.

O. Sekiguchi, M. C. Letzel, D. Kuck, E. Uggerud
The unimolecular dissociation of protonated glyoxylic acid: Structure and dynamics of a step-by-step process
Int. J. Mass Spectrom. 2006, 255-256, 177-184.

Tobias Schulte, Kai Oliver Siegenthaler, Heinrich Luftmann, Matthias Letzel, Armido Studer
Nitroxide-mediated polymerization of N-isopropylacrylamide: Electrospray ionization mass spectrometry, matrix-assisted laser desorption ionization mass spectrometry, and multiple-angle laser light scattering studies on nitroxide-terminated poly-N-isopropylacrylamides
Macromolecules 2005, 38, 6833-6840.

Alexander B. Rozhenko, Wolfgang W. Schoeller, Matthias C. Letzel, Björn Decker, Ceno Agena, Jochen Mattay
Conformational Features of Calix[4]arenes with Alkali Metal Cations: A Quantum Chemical Investigation with Density Functional Theory
Theochem. 2005, 732, 7-20.

Mareke Oley, Matthias C. Letzel, Hermann Ragg
Inhibition of furin by serpin Spn4A from Drosophila melanogaster
FEBS Letters 2004, 577, 165-169.

Ahmad Mehdizadeh, Matthias C. Letzel, Björn Decker, Ceno Agena, Jochen Mattay
Chiral discrimination on the host-guest-complexationof resorc[4]arenes with quaternary amines
Eur. J. Mass Spectrom. 2004, 10 (5), 649-655.

Matthias C. Letzel, Björn Decker, Axexander B. Rozhenko, Wolfgang W. Schoeller, Jochen Mattay
Encapsulated Guest Molecules in Dimers of Octahydroxypyridine[4]arenes
J. Am. Chem.Soc. 2004, 126, 9669-9674.

Eduardo A. Leitão, Vera C. B. Bittencourt, Rosa M. T. Haido, Anna P. Valente, Jasna Peter-Katalinić, Matthias Letzel, Lauro M. de Souza, Eliana Barreto-Bergter
β-Galactofuranose-containing O-linked oligosaccharides present in the cell wall peptidogalactomannan of Aspergillus fumigatus contain immunodominant epitopes
Glycobiology 2003, 13, 681-692.

Matthias C. Letzel, Hans-Friedrich Grützmacher, Thomas Fürst, Klaus K. Mayer, Wolfgang Wiegrebe
Functional group migration in benzaldoxime-O-n-propyl ether radical cation,
Int. J. Mass Spectrom. 2002, 217, 153-168.

Sven Bahrke, Jon M. Einarsson, Johannes Gislason, Sophie Haebel, Matthias C. Letzel, Jasna Peter-Katalinić, Martin G. Peter
Sequence Analysis of Chitooligosaccharides by Matrix-Assisted Laser Desorption/Ionization Postsource Decay Mass Spectrometry,
Biomacromolecules 2002, 3, 696-704.

Achim Müller, Ekkehard Diemann, S. Qaiser Nazir Shah, Christoph Kuhlmann and Matthias C. Letzel
Soccer-playing metal oxide giant spheres: a first step towards pattering structurally well defined nano-objects colletcives
Chem. Commun. 2002, 5, 440-441.

Matthias C. Letzel, Ceno Agena and Jochen Mattay
Investigation of Homo- and Heterodimer Alkali Metal Cation Complexes of Resorc[4]arens by Electrospray Ionization Mass Spectrometry
J. Mass Spectrometry 2002, 37, 83-68.

Matthias C. Letzel, Ceno Agena and Jochen Mattay
Calibration of Electrospray Mass Spectrometers with rccc-2,8,14,20-tetra-n-octyl-5,11,17,23-
tetrahydroxyresorc[4]arene in the high Mass Range up to m/z 6,000
Eur. J. Mass Spectrometry 2001, 7, 35-38.

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