Research Group of Prof. Dr. Uwe Karst

Druckkopf Universität Münster
Research Group of Prof. Dr. Uwe Karst
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Prof. Dr. Uwe Karst
University of Muenster
Institute of Inorganic and
Analytical Chemistry
Corrensstraße 30
D-48149 Muenster

+49 (251) 83-33141

+49 (251) 83-36013

uk at
uni-muenster dot de




Original Papers
Reviews, Books, Misc. Publications

> 200 lectures and posters at international conferences.

Original Papers

Frensemeier, L.M., Büter, L., Vogel, M., Karst, U.
Investigation of the oxidative transformation of roxarsone by electrochemistry coupled to hydrophilic interaction liquid chromatography/mass spectrometry
J. Anal. At. Spectrom., 32, 153-161 (2017).
DOI: 10.1039/C6JA00277C

Büter, L., Frensemeier, L.M., Vogel, M., Karst, U.
Dual reductive/oxidative electrochemistry/liquid chromatography/mass spectrometry: Towards peptide and protein modification, separation and identification,
J. Chrom. A, 1479, 153-160 (2017).
DOI: 10.1016/j.chroma.2016.12.008

Hachmöller, O.; Guilherme Buzanich, A.; Aichler, M.; Radtke, M; Dietrich, D.; Schwamborn, K.; Lutz, L.; Werner, M.; Sperling, M.; Walch, A.; Karst, U.
Elemental bioimaging and speciation analysis for the investigation of Wilson´s disease using µXRF and XANES
Metallomics, 8 648-653 (2016).
DOI: 10.1039/c6mt00001k

Hachmöller, O.; Aichler, M.; Schwamborn, K.; Lutz, L.; Werner, M.; Sperling, M.; Walch, A.; Karst, U.
Element bioimaging of liver needle biopsy specimens from patients with Wilson´s disease by laser ablation-inductively coupled plasma-mass spectrometry
J. Trace Elem. Med. Biol., 35 97-102 (2016).
DOI: 10.1016/j.jtemb.2016.02.001

Birka, M.; Wehe, C. A.; Hachmöller, O.; Sperling, M.; Karst, U.
Tracing gadolinium-based contrast agents from surface water to drinking water by means of speciation analysis
J. Chrom. A., 1440 105-111 (2016).
DOI: 10.1016/j.chroma.2016.02.050

Hogeback, J.; Schwarzer, M.; Wehe, C.A.; Sperling, M.; Karst, U.;
Investigating the adduct formation of organic mercury species with carbonic anhydrase and hemoglobin from human red blood cell hemolysate by means of LC/ESI-TOF-MS and LC/ICP-MS
Metallomics, (2015).
DOI: 10.1039/C5MT00186B

Niehoff, A.-C.; Bauer, O. B.; Kröger, S.; Fingerhut, S.; Schulz, J.; Meyer, S.; Sperling, M.; Jeibmann, A.; Schwerdtle, T.; Karst, U.;
Quantitative Bioimaging to Investigate the Uptake of Mercury Species in Drosophila melanogaster
Analytical Chemistry, 87 10392-10396 (2015).
DOI: 10.1021/acs.analchem.5b02500

Kotz, S.; Kullmann, M.; Crone, B.; Kalayda, G.V.; Jaehde, U.; Metzger, S.;
Combination of two-dimensional gel electrophoresis and a fluorescent carboxyfluorescein diacetate labeled cisplatin analogue allows the identification of intracellular cisplatin-protein adducts
Electrophoresis, 00 1–9 (2015).
DOI: 10.1002/elps.201500188

Büter, L.; Faber, H.; Wigger, T.; Vogel, M.; Karst, U.;
Differential Protein Labeling Based on Electrochemically Generated Reactive Intermediates
Analytical Chemistry,  87 19 9931–9938 (2015).  
DOI: 10.1021/acs.analchem.5b02497

Große Brinkhaus, S.; Bornhorst, J.; Chakraborty, S.; Wehe, C. A.; Niehaus, R.; Reifschneider, O.; Aschner, M.; Karst, U.;
Elemental bioimaging of manganese uptake in C. elegans
Metallomics, 6 617 – 621 (2014).
DOI:  10.1039/C3MT00334E

Niehaus, R.; Sperling, M.; Karst, U.;
Study on aerosol characteristics and fractionation effects of organic standard materials for bioimaging by means of LA-ICP-MS
J. Anal. At. Spectrom., Advance Article (2015).
DOI: 10.1039/C5JA00221D

van den Brink, F. T.; Büter, L.; Odijk, M.; Olthuis, W.; Karst, U.; van den Berg, A.;
Mass Spectrometric Detection of Short-Lived Drug Metabolites Generated in an Electrochemical Microfluidic Chip
Analytical Chemistry87 1527-1535 (2015).
DOI: 10.1021/ac503384e

Büter, L.; Vogel, M.; Karst, U.;
Adduct formation of electrochemically generated reactive intermediates with biomolecules
TrAC, Trends in Analytical Chemistry70 74-91 (2015).
DOI: 10.1016/j.trac.2015.03.009

Crone, B.; Aschner, M.; Schwerdtle, Karst, U.; Bornhorst, J.;
Elemental bioimaging of Cisplatin in Caenorhabditis elegans by LA-ICP-MS
Metallomics,7 1189-1195 (2015).
DOI: 10.1039/c5mt00096c

Birka, M.; Wentker, K. S.; Lusmöller, E.; Arheilger, B.; Wehe, C. A.; Sperling, M.; Stadler, R.; Karst, U.;
Diagnosis of Nephrogenic Systemic Fibrosis by means of Elemental Bioimaging and Speciation Analysis
Analytical Chemistry, 87 3321-3328 (2015).
DOI: 10.1021/ac504488k

Faber, H., Lutze, H., Lareo, P.L., Frensemeier, L., Vogel, M., Schmidt, T.C., Karst, U.
Liquid chromatography/mass spectrometry to study oxidative degradation of environmentally relevant pharmaceuticals by electrochemistry and ozonation,
J. Chrom. A, 1343, 152-159 (2014).
DOI: 10.1016/j.chroma.2014.03.081

Wehe, C. A.; Niehoff, A.-C.; Thyssen, G. M.; Sperling, M.; Karst, U.;
Rapid cell mode switching and dual laser ablation inductively coupled plasma mass spectrometry for elemental bioimaging
Rapid Communications in Mass Spectrometry 28 2627-2635 (2014)
DOI: 10.1002/rcm.7054

Woltmann, E.; Meyer, H.; Weigel, D.; Pritzke, H.; Posch, T. N.; Kler, P. A.; Schürmann, K.; Roscher, J.; Huhn, C.
"Applicability of UV laser-induced solid-state fluorescence spectroscopy for characterization of solid dosage forms"
Analytical and Bioanalytical Chemistry, 2014 Aug 9.
DOI: 10.1007/s00216-014-8074-3

Roscher, J.; Faber, H.; Stoffels, M.; Hachmöller, O.; Happe, J.; Karst, U.
"Nonaqueous capillary electrophoresis as separation technique to support metabolism studies by means of electrochemistry and mass spectrometry"
Electrophoresis, 35(16) 2386–2391 (2014).
DOI: 10.1002/elps.201300652

Nowak, S.; Gesell, M.; Holtkamp, M.; Scheffer, A.; Sperling, M.; Karst, U.; Buscher, W.;
Low gas flow inductively coupled plasma optical emission spectrometry for the analysis of food samples after microwave digestion
Talanta, 129 575-578 (2014).
DOI: 10.1016/j.talanta.2014.06.045

Niehoff, A. C.; Moosmann, A.; Söbbing, J.; Wiehe, A.; Mulac, D.; Wehe, C. A.; Reifschneider, O.; Blaske, F.; Wagner, S.; Sperling M.; von Briesen, H.; Langer, K.; Karst, U.;
A palladium label to monitor nanoparticle-assisted drug delivery of a photosensitizer into tumor spheroids by elemental bioimaging
Metallomics 6 1 77-81 (2014).
DOI: 10.1039/c3mt00223c

Wehe, C. A..; Beyer, G.; Sperling, M.; Ciarimbolib, G.; Kars, U.;
Assessing the intracellular concentration of platinum in medulloblastoma cell lines after Cisplatin incubation
Journal of Trace Elements in Medicine and Biology 28 2 166-172 (2014).
DOI: 10.1016/j.jtemb.2014.01.001

Blaske, F.; Reifschneider, O.; Gosheger, G.; Wehe. C. A.; Sperling, M.; Kars, U.; Hauschild, G.; Höll, S.;
Elemental Bioimaging of Nanosilver-Coated Prostheses Using X-ray Fluorescence Spectroscopy and Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry
Analytical Chemistry 86 1 615-620 (2014).
DOI: 10.1021/ac4028577

Truempler, S.; Meermann, B.; Nowak, S.; Buscher, W.; Karst, U.; Sperling, M.;
In vitro study of thimerosal reactions in human whole blood and plasma surrogate samples
Journal of Trace Elements in Medicine and Biology 28 2 125-130 (2014).
DOI: 10.1016/j.jtemb.2014.01.006

Wehe, C. A.; Pieper, I.; Holtkamp, M.; Thyssen G. M.; Sperling, M.; Schwerdtle, T.; Karst, U.;
On-line species-unspecific isotope dilution analysis in the picomolar range reveals the time- and species-depending mercury uptake in human astrocytes
Analytical and Bioanalytical Chemistry, 406 7 1909–1916 (2014).
DOI: 10.1007/s00216-013-7608-4

Leffers, L.;  Wehe C. A.;  Hüwel S.;  Bartel M.;  Ebert F.;  Taleshi M. S.;  Galla H.J.;  Karst U.; Francesconi  K.A.;  Schwerdtle T.;
In vitro intestinal bioavailability of arsenosugar metabolites and presystemic metabolism of thio-dimethylarsinic acid in Caco-2 cells
Metallomics, 5 1031–1042 (2013).
DOI: 10.1039/c3mt00039g   

Reifschneider, O.; Wehe, C. A.; Raj, I.; Ehmcke, J.; Ciarimboli, G.; Sperling M.; Karst, U;
Quantitative bioimaging of platinum in polymer embedded mouse organs using laser ablation ICP-MS
Metallomics, 5 1440–1447 (2013).
DOI: 10.1039/C3MT00147D

Herdering, C; Wehe, C. A.; Reifschneider, O; Raj, I; Ciarimboli G.; Diebold K.; Becker C.; Sperling M.; Karst U.;
Laser ablation based bioimaging with simultaneous elemental and molecularmass spectrometry: towards spatially resolved speciation
Rapid Commun. Mass Spectrom., 27 2588–2594 (2013).
DOI: 10.1002/rcm.6726

Herdering, C.; Reifschneider, O.; Wehe, C. A.; Sperling, M.; Karst, U.;
Ambient molecular imaging by laser ablation atmospheric pressure chemical ionization mass spectrometry
Rapid Commun. Mass Spectrom., 27 2595–2600 (2013).
DOI: 10.1002/rcm.6727

Blaske, F.; Stork, L.; Sperling, M.; Karst U.;
Adduct formation of ionic and nanoparticular silver with amino acids and glutathione
J. Nanoparticle Res., 15 1928–1938 (2013).
DOI: 10.1007/s11051-013-1928-3  

Simon, H.; Wehe, C. A.; Pajaziti, B.; Heinrich, L.; Karst, U.;
Simultaneous electrochemical oxidation/ionization of a selenoxanthene revealed by on-line electrospray-high resolution mass spectrometry
Electrochimica Acta, 111 324–331 (2013).
DOI: 10.1016/j.electacta.2013.08.070

Birka, M.; Wehe, C. A.; Telgmann, L.; Sperling, M.; Karst, U.;
Sensitive quantification of gadolinium-based magnetic resonance imaging contrast agents in surface waters using hydrophilic interaction liquid chromatography and inductively coupled plasma sector field mass spectrometry
Journal of Chromatography A, 1308 125-131 (2013).
DOI: 10.1016/j.chroma.2013.08.017

Rajesh Munirathinam, Roberto Ricciardi, Richard J. M. Egberink, Jurriaan Huskens, Michael Holtkamp, Herbert Wormeester, Uwe Karst and Willem Verboom
Gallium-containing polymer brush film as efficient supported Lewis acid catalyst in a glass microreactor,
Beilstein J. Org. Chem. 9 1698–1704 (2013).

Verena Hoerr, Lorena Tuchscherr, Jana Hüve, Nadine Nippe, Karin Loser, Nataliya Glyvuk, Yaroslav Tsytsyura, Michael Holtkamp, Cord Sunderkötter, Uwe Karst, Jürgen Klingauf, Georg Peters, Bettina Löffler, Cornelius Faber
Bacteria tracking by in vivo magnetic resonance imaging,
BMC Biology, 11 63 (2013).

Richard Stange, Daniel Kronenberg, Melanie Timmen, Jens Everding, Heriburg Hidding, Beate Eckes, Uwe Hansen, MichaelHoltkamp, Uwe Karst, Thomas Pap, Michael J. Raschke
Age-related bone deterioration is diminished by disrupted collagen sensing in integrin α2β1 deficient mice
Bone56 1 48-54 (2013).

Michael Holtkamp, Tim Elseberg, Christoph A. Wehe, Michael Sperling, Uwe Karst,
Complexation and oxidation strategies for improved TXRF determination of mercury in vaccines,
J. Anal. At. 
Spectrom., 28 719-723 (2013).
DOI: 10.1039/c3ja00002h

Olga Reifschneider, Christoph A. Wehe, Kurt Diebold, Christoph Becker, Michael Sperling, Uwe Karst,
Elemental bioimaging of haematoxylin and eosin-stained tissues by laser ablation ICP-MS,
J. Anal. At. Spectrom., 28 989-993 (2013).
DOI: 10.1039/c3ja50046b

Brauckmann, C; Wehe, C. A.; Kieshauer, M. Lanvers-Kaminsky, C.; Sperling, M.; Karst, U.;
The interaction of platinum-based drugs with native biologically relevant proteins
Analytical and Bioanalytical Chemistry, 405 1855–1864 (2013).
DOI: 10.1007/s00216-012-6410-z

Christine Brauckmann, Helene Faber, Claudia Lanvers-Kaminsky, Michael Sperling, Uwe Karst,
Influence of cimetidine and its metabolites on Cisplatin—Investigation of adduct formation by means of electrochemistry/liquid chromatography/electrospray mass spectrometry
J. Chromatogr. A., 1279 49–57 (2013).
DOI: 10.1016/j.chroma.2012.12.069

Lena Telgmann, Michael Sperling, Uwe Karst,
Speciation of Gd-based MRI contrast agents in biological and environmental samples: A review,
Anal. Chim. Acta, 764 1-16 (2013).
DOI: 10.1016/j.aca.2012.12.007

Simon, H.; Melles, D.; Jacquoilleot, S.; Sanderson, P.; Zazzeroni, R.; Karst, U.;
Combination of Electrochemistry and Nuclear Magnetic Resonance Spectroscopy for Metabolism Studies
Anal. Chem., 84 (20) 8777–8782 (2012).
DOI: 10.1021/AC302152A

Telgmann, L; Wehe, C. A.; Birka, M.; Künnemeyer, J.; Nowak, S.; Sperling, M.; Karst, U.;
Speciation and Isotope Dilution Analysis of Gadolinium-Based Contrast Agents in Wastewater
Environmental Science and Technology, 46 11929-11936 (2012).
DOI: 10.1021/ES301981Z

Telgmann, L; Wehe, C. A.; Künnemeyer, J.; Bülter, A.-C.; Sperling, M.; Karst, U.;
Speciation of Gd-based MRI contrast agents and potential products of transmetalation with iron ions or parenteral iron supplements
Analytical and Bioanalytical Chemistry, 404 2133-2141 (2012).
DOI: 10.1007/S00216-012-6404-X

Holtkamp, M.; Wehe, C. A.; Blaske, F.; Holtschulte C.; Sperling, M.; Karst, U.
Nitrogen purged TXRF for the quantification of silver and palladium
J. Anal. Atomic Spectrom., 27 1799-1802 (2012).
DOI: 10.1039/C2JA30117B

Jahn, S.; Faber, H; Zazzeroni, R.; Karst, U.
Electrochemistry/mass spectrometry as a tool in the investigation of the potent skin sensitizer p-phenylenediamine and its reactivity toward nucleophiles
Rapid Commun. Mass Spectrom., 26(12) 1453–1464 (2012).
DOI: 10.1002/rcm.6249

Jahn, S.; Faber, H; Zazzeroni, R.; Karst, U.
Electrochemistry/liquid chromatography/mass spectrometry to demonstrate irreversible binding of the skin allergen p-phenylenediamine to proteins
Rapid Commun. Mass Spectrom., 26(12) 1415–1425 (2012).
DOI: 10.1002/rcm.6247

Jahn, S.; Karst, U.
Electrochemistry coupled to (liquid chromatography/) mass spectrometry - Current state and future perspectives
Journal of Chromatography A, (2012).
DOI: 10.1016/j.chroma.2012.05.066

Bornhorst, J.; Wehe, C. A.; Hüwel, S.; Karst, U.; Galla, H.-J.; Schwerdtle, T;
Impact of Manganese on and Transfer across Blood-Brain and Blood-Cerebrospinal Fluid Barrier in Vitro
J. Biol. Chem. 28 17140–17151 (2012).
DOI: 10.1074/JBC.M112.344093

Albert, A.; Brauckmann, C.; Blaske, F.; Sperling, M.; Engelhard, C.; Karst, U.;
Speciation analyisis of the antirheumatic agent Auanofin and its thiol adducts by LC/ESI/MS and LC/ICP-MS
J. Anal. Atom. Spectrom. 27 975–981 (2012).
DOI: 10.1039/C2JA30109A

Telgmann, L; Faber, H.; Jahn, S.; Melles, D.; Simon, H.; Sperling, M.; Karst, U.;
Identification and Quantification of Potential Metabolites of Gd-Based Contrast Agents by Electrochemistry/Separations/Mass Spectrometry
Journal of Chromatography A, 1240 147–155 (2012).
DOI: 10.1016/J.CHROMA.2012.03.088

Faber, H.; Melles, D.; Brauckmann, C.; Wehe, C. A.; Wentker, K.; Karst, U.
"Simulation of the oxidative metabolism of diclofenac by electrochemistry/(liquid chromatography/)mass spectrometry "
Anal. Bioanal. Chem.
DOI: 10.1007/S00216-011-5665-0

Petroutsos, D.; Busch, A.; Janßen, I.; Trompelt, K.; Bergner, S. V.; Weinl, S.; Holtkamp, M.; Karst, U.; Kudla, J.; Hippler, M.;
"The chloroplast calcium sensor CAS is required for photoacclimation in Chlamydomonas reinhardtii"
Plant cell, 23/8 2950–2963 (2011).
DOI: 10.1105/TPC.111.087973

Wehe, C. A.; Bornhorst, J.; Holtkamp, M.; Sperling, M.; Galla, H. J.; Schwerdtle, T.; Karst, U.
"Fast and low sample consuming quantification of manganese in cell nutrient solutions by flow injection ICP-QMS"
Metallomics, 3/12 1291–1296 (2011).
DOI: 10.1039/C1MT00170A

Jahn, S.; Baumann, A; Roscher, J.; Hense, K.; Zazzeroni, R.; Karst, U.
"Investigation of the biotransformation pathway of verapamil using electrochemistry/liquid chromatography/mass spectrometry – A comparative study with liver cell microsomes"
J. Chromatogr. A, 1218(51) 9210-9220 (2011).
DOI: 10.1016/J.CHROMA.2011.10.052

Jahn, S.; Lohmann, W.; Bomke, S.; Baumann, A.;Karst, U.
"A ferrocene-based reagent for the conjugation and quantification of reactive metabolites"
Anal. Bioanal. Chem., 402(1) 461-471 (2012).
DOI: 10.1007/S00216-011-5388-2

Faber, H.; Jahn, S.; Künnemeyer, J.; Simon, H.; Melles, D.; Vogel, M.; Karst, U.
"Electrochemistry/Liquid Chromatography/Mass Spectrometry as a Tool in Metabolism Studies"
Angew. Chem. Int. Ed. Engl., 50 A52-A58 (2011).

Telgmann, L.; Holtkamp, M.; Künnemeyer, J.; Gelhard, C.; Hartmann, M.; Klose, A.; Sperling, M.; Karst, U.;
Simple and rapid quantification of gadolinium in urine and blood plasma samples by means of total reflection X-ray fluorescence (TXRF)
Metallomics 30 1766-1773 (2011).
DOI: 10.1039/c1mt00054c.

Janzen R.; Schwarzer M.; Sperling M.;Vogel M.; Schwerdtle T.; Karst U.
"Adduct formation of Thimerosal with human and rat hemoglobin: a study using liquid chromatography coupled to electrospray time-of-flight mass spectrometry (LC/ESI-TOF-MS)"
Metallomics, 3/8 847–852 (2011).
DOI: 10.1039/C1MT00043H.

Veldboer, K.; Schürmann, T.; Vogel, M.; Wiemhöfer, H.-D.; Karst, U.
"Liquid chromatography/electrospray time-of-flight mass spectrometry for the characterisation of cyclic phosphazenes"
Rapid Commun. Mass Spectrom., 25 147-154 (2011).

Bomke, S.; Pfeifer, T.; Meermann, B.; Buscher, W.; Karst U.
"Liquid Chromatography with Complementary Electrospray and Inductively Coupled Plasma Mass Spectrometric Detection of Ferrocene-Labelled Peptides and Proteins"
Anal. Bioanal. Chem., 397 3503-3513 (2010).

Baumann, A.; Lohmann, W.; Jahn, S.; Karst, U.
"On-Line Electrochemistry/Electrospray Ionization Mass Spectrometry (EC/ESI-MS) for the Generation and Identification of Nucleotide Oxidation Products"
Electroanalysis, 22 286-292 (2010).

Siemerink, M.; Schebb, N. H.; Liesener, A.; Perchuc, A. M.; Schoni, R.; Wilmer, M; Hayen, H; Karst, U.; Vogel, M.
"Development of a fast liquid chromatography/mass spectrometry screening method for angiotensin-converting enzyme (ACE) inhibitors in complex natural mixtures like snake venom"
Rapid Comm. Mass Spectrom., 24 687-697 (2010).

Baumann, A.; Karst, U.
"Online electrochemistry/mass spectrometry in drug metabolism studies: principles and applications"
Expert Opin Drug Metab Toxicol, 6 715-731 (2010).

Bomke, S.; Sperling, M.; Karst, U.
"Organometallic derivatizing agents in bioanalysis"
Anal. Bioanal. Chem., 397 3483-3494 (2010).

Rauschenberg, M; Bomke, S; Karst, U; Ravoo, BJ
"Dynamic Peptides as Biomimetic Carbohydrate Receptors"
Angew. Chem. Int. Edit., 49 7340-7345 (2010).

Meermann, B.; Möller, I.; Nowak, S.; Luftmann, H.; Karst, U.
"Iodine speciation using thin-layer chromatography coupled to inductively coupled plasma-mass spectrometry by means of an extraction device"
JAAS, 25 1654-1658 (2010).

Baumann, A; Lohmann, W; Rose, T; Ahn, K. C.; Hammock, B. D.; Karst, U.; Schebb, N. H.
"Electrochemistry-Mass Spectrometry Unveils the Formation of Reactive Triclocarban Metabolites"
Drug Metabol. Disp., 38 2130-2138 (2010).

Wilken A.; Janzen R.; Holtkamp M.; NowakS.; Sperling M.;Vogel M.; Karst U.
"Investigation of the interaction of Mercurochrome constituents with proteins using liquid chromatography/mass spectrometry"
Anal. Bioanal. Chem., 397 3525-3532 (2010).
DOI: 10.1007/s00216-010-3842-1.

Bräutigam, A.; Bomke, S.; Pfeifer, T.; Karst, U.; Krauss, G.J.; Wesenberg, D.;
Quantification of Phytochelatins in Chlamydomonas reinhardtii using ferrocene-based derivatization
Metallomics, 2 565-570 (2010).

Trümpler, S.; Nowak, S.; Meermann, B.; Wiesmüller, G.A.; Buscher, W.; Sperling, M.; Karst, U.;
Detoxification of mercury species—an in vitro study with antidotes in human whole blood ,
Anal. Bioanal. Chem., 395 1929-1935 (2009).
DOI: 10.1007/s00216-009-3105-1.

Bomke, S.; Pfeifer, T.; Meermann, B.; Buscher, W.; Karst U.
Liquid Chromatography with Complementary Electrospray and Inductively Coupled Plasma Mass Spectrometric Detection of Ferrocene-Labelled Peptides and Proteins
Anal. Bioanal. Chem., 397 3503-3513 (2010)
DOI 10.1007/s00216-009-3123-z (2009)

Schebb, N.H.; Falck, D.; Faber, H.; Hein, E.-M.; Karst, U.; Hayen, H.
A fast LC-ESI-MS method for monitoring phospholipase A2 activity
J. Chromatogr. A 1216 5249-5255 (2009)

Baumann, A.; Lohmann, W.; Schubert, B.; Oberacher, H.; Karst, U.
Metabolic studies of tetrazepam based on electrochemical simulation in comparison to in vivo and in vitro methods
Journal of Chromatography A 1216 3192-3198 (2009)

Odijk, M.; Baumann, A.; Lohmann, W.; van den Brink, F. T. G.; Olthus, W.; Karst, U.; van den Berg, A.
A microfluidic chip for electrochemical conversions in drug metabolism studies
Lab Chip 9 1687-1693 (2009)

Schebb, N.H.; Vielhaber, T.; Jousset, A.; Karst, U.
Development of a Liquid Chromatography-Based Screening Methodology for Proteolytic Enzyme Activtiy
J. Chromatogr. A 1216 4407-4415 (2009)

Schebb, N.H.; Faber, H.; Maul, R.; Heus, F.; Kool, J.; Irth, H.; Karst, U.
Analysis of glutathione adducts of patulin by means of liquid chromatography (HPLC) with biochemical detection (BD) and electrospray ionization tandem mass spectrometry (ESI-MS/MS)
Anal. Bioanal. Chem.
394 1361-1373 (2009)

Künnemeyer, J.; Terborg, L.; Meermann, B.; Brauckmann, C.; Möller, I.; Scheffer, A.; Karst, U.;
Speciation Analysis of Gadolinium Chelates in Hospital Effluents and Wastewater Treatment Plant Sewage by a Novel HILIC/ICP-MS Method
Environ. Sci. Technol. 43 2884-2890 (2009)

Künnemeyer J., Terborg L., Nowak S., Telgmann L., Tokmak F., Krämer B., Günsel A., Wiesmüller G. A., Waldeck J., Bremer C., Karst U.,
Analysis of the Contrast Agent Magnevist® and its Transmetallation Products in Blood Plasma by CE/ESI-TOF-MS
Anal. Chem. 81 3600-3607 (2009)

Künnemeyer, J.; Terborg, L.; Nowak, S.; Telgmann, L.; Brauckmann, C.; Albert, A.; Tokmak, F.; Günsel, A.; Wiesmüller, G. A.; Karst, U.
Quantification and excretion kinetics of a MRI contrast agent by capillary electrophoresis-mass spectrometry
Electrophoresis 30 1766-1773 (2009)

Lohmann, W.; Karst, U.
Electrochemistry meets enzymes: instrumental on-line simulation of oxidative and conjugative metabolism reactions of toremifene
Anal. Bioanal. Chem. 394 1341-1348 (2009)

Lohmann, W.; Dötzer, R.; Gütter, G.; Van Leeuwen, S.M.; Karst, U.
On-line electrochemistry/liquid chromatography/mass spectrometry for the simulation of pesticide metabolism
J. Amer. Soc. Mass Spectrom. 20 138-145 (2009)

Bomke, S.; Seiwert, B.; Dudek, L.; Effkemann, S.; Karst, U.
Liquid chromatography/mass spectrometry method for the determination of biogenic amines in food samples
Anal. Bioanal. Chem. 393 247-256 (2009)

Trümpler, S.; Lohmann, W.; Meermann, B.; Buscher, W.; Sperling, M.; Karst, U.
Interaction of thimerosal with proteins - ethylmercury adduct formation of human serum albumin and ß-lactoglobulin A
Metallomics 1 87-91 (2009)

Steinkamp, T.; Hayen, H.; Huskens, J.; Karst, U.
Lanthanide-induced hydrolysis of 4,7-diphenyl-1,10-phenanthroline-2,9-dicarboxylic acid esters
Inorg. Chim. Acta 362 421-425 (2009)

Lohmann, W.; Meermann, B.; Möller, I.; Scheffer, A.; Karst, U.
Quantification of electrochemically generated iodine-containing metabolites using inductively coupled plasma mass spectrometry
Anal. Chem. 80 9769-9775 (2008)

Künnemeyer, J.; Terborg, L.; Nowak, S.; Scheffer, A.; Telgmann, L.; Tokmak, F.; Günsel, A.; Wiesmüller, G.A.; Reichelt, S.; Karst, U.
Speciation analysis of gadolinium-based MRI contrast agents in blood plasma by hydrophilic interaction chromatography/electrospray mass spectrometry (HILIC/ESI-MS)
Anal. Chem. 80 8163-8170 (2008)

Lohmann, W.; Hayen. H.; Karst, U
Covalent protein modification by reactive drug metabolites using on-line electrochemistry/liquid chromatography/mass spectrometry
Anal. Chem., 80 9714-9719 (2008)

Veldboer, K.; Karatas, Y.; Vielhaber, T.; Karst, U.; Wiemhöfer, H.-D.
Cyclic phosphazenes for the surface modification of lanthanide phosphate-based nanoparticles
Z. Allg. Anorg. Chem. 634 2175-2180 (2008)

Thevis, M.; Lohmann, W.; Schrader, Y.; Kohler, M.; Bornatsch, W.; Karst, U.; Schänzer, W.
Use of an electrochemically synthesized metabolite of a selective androgen receptor modulator for mass spectrometry-based sports drug testing
Eur. J. Mass Spectrom. 14 163-170 (2008)

Schebb, N.H.; Heus, F.; Saenger, T.; Karst, U.; Irth, H.; Kool, J.
Development of a countergradient parking system for gradient liquid chromatography with on- line biochemical detection of serine protease inhibitors
Anal. Chem. 80 6764-6772 (2008)

Meermann, B.; Bartel, M.; Scheffer, A.; Trümpler, S.; Karst, U.
Capillary electrophoresis with inductively coupled plasma-mass spectrometric and electrospray time of flight mass spectrometric detection for the determination of arsenic species in fish samples
Electrophoresis 29 2731-2737 (2008)

Schebb, N.H.; Fischer, D.; Hein, E.-M.; Hayen, H.; Krieglstein, J.; Klumpp, S.; Karst, U.
Fast sample preparation and liquid chromatography-tandem mass spectrometry method for assaying cell lysate acetylcholine
J. Chromatogr. A 1183 100-107 (2008)

Engelhard, C.; Vielhaber, T.; Scheffer, A.; Brocksieper, M.; Buscher, W.; Karst, U.
Analysis of doped luminescent lanthanide fluoride nanoparticles by low gas flow inductively coupled plasma optical emission spectrometry
J. Anal. At. Spectrom. 23 407-411 (2008)

Seiwert, B.; Hayen, H.; Karst, U.
Differential labeling of free and disulfide-bound thiol functions in proteins
J. Amer. Soc. Mass Spectrom. 19 1-7 (2008)

Lohmann, W.; Karst, U.
Generation and identification of reactive metabolites by electrochemistry and immobilized enzymes coupled on-line to liquid chromatography/mass spectrometry
Anal. Chem. 79 6831-6839 (2007)

Seiwert, B.; Karst, U.
Simultaneous LC/MS/MS determination of thiols and disulfides in urine samples based on differential labelling with ferrocene-based maleimides
Anal. Chem. 79 7131-7138 (2007)

Van Leeuwen, S.M.; Tan, B.; Grijpma, D.; Feijen, J.; Karst, U.
Characterization of a block copolymer´s chemical composition by combining LC/APCI-MS and LC/ESI-MS
Rapid Commun. Mass Spectrom. 21 2629-2637 (2007)

Liesener, A.; Perchuc, A.-M.; Schöni, R.; Schebb, N.H.; Wilmer, M.; Karst, U.
Screening of acetylcholinesterase inhibitors in snake venom by electrospray mass spectrometry
Pure Appl. Chem. 79 2339-2349 (2007)

Revermann, T.; Götz, S.; Karst, U.
Quantitative analysis of thiols in consumer products on a microfluidic capillary electrophoresis chip with fluorescence detection
Electrophoresis 28 1154-1160 (2007)

Seiwert, B.; Karst, U.
Analysis of cysteine-containing proteins using precolumn derivatization with N-(2- ferroceneethyl)maleimide and liquid chromatography/electrochemistry/mass spectrometry
Anal. Bioanal. Chem. 388 1633-1642 (2007)

Götz, S.; Karst, U.
Wavelength-resolved fluorescence detector for microchip capillary electrophoresis separations
Sens. Act. B 123 622-627 (2007)

Götz, S.; Revermann, T.; Karst, U.
Quantitative on-chip determination of taurine in energy and sports drinks
Lab Chip 7 93-97 (2007)

Henneken, H.; Hayen, H.; Vogel, M.; Karst, U.
Validation of a diffusive sampling method for airborne low-molecular isocyanates using 4-nitro- 7-piperazinobenzo-2-oxa-1,3-diazole-impregnated filters and liquid chromatography-tandem mass spectrometry
J. Chromatogr. A 1134 112-121 (2006)

Henneken, H.; Vogel, M.; Karst, U.
Effects of humidity and filter material on diffusive sampling of isocyanates using reagent- coated filters
J. Environ. Monit. 8 1014-1019 (2006)

Schulte-Ladbeck, R.; Edelmann, A.; Quintas, G.; Lendl, B.; Karst, U.
Determination of peroxide-based explosives using liquid chromatography with on-line infrared detection
Anal. Chem. 78 8150-8155 (2006)

Lohmann, W.; Karst, U.
Simulation of the Detoxification of Paracetamol Using On-line Electrochemistry/Liquid Chromatography/Mass Spectrometry
Anal. Bioanal. Chem. 386 1701-1708 (2006)

Henneken, H.; Assink, L.; de Wit, J.; Vogel, M.; Karst, U
Passive sampling of airborne peroxyacetic acid
Anal. Chem. 78 6547-6555 (2006)

Schoon, A.; Götz, S.; Heuven, M.; Vogel, M.; Karst, U.
Training and testing explosive detection dogs in detecting TATP
Forensic Sci. Commun. 8 (2006)

Hempen, C.; Gläsle-Schwarz, L.; Kunz, U.; Karst, U.
Determination of telmisartan in human blood plasma. Part II: liquid chromatography-tandem mass spectrometry method development, comparison to immunoassay and pharmacokinetic study
Anal. Chim. Acta 560 35-40 (2006)

Hempen, C.; Gläsle-Schwarz, L.; Kunz, U.; Karst, U.
Determination of telmisartan in human blood plasma. Part I: Immunoassay development
Anal. Chim. Acta 560 35-40 (2006)

Haselberg, R.; Hempen, C.; Van Leeuwen, S.M.; Vogel, M.; Karst, U.
Analysis of microperoxidases using liquid chromatography, post-column substrate conversion and fluorescence detection
J. Chromatogr. B 830 47-53 (2006)

Liesener, A.; Perchuc, A.-M.; Schöni, R.; Wilmer, M., Karst, U.
Screening for proteolytic activities in snake venom by means of a multiplexing electrospray ionization mass spectrometry assay scheme
Rapid Commun. Mass Spectrom. 19 2923-2928 (2005)

Hempen, C.; Liesener, A.; Karst, U.
Fluorescence and mass spectrometric detection schemes for simultaneous enzymatic conversions: method development and comparison
Anal. Chim. Acta 543 137-142 (2005)

Liesener, A.; Karst, U.
Turbulent flow chromatography for the reduction of matrix effects in electrospray ionization mass spectrometry-based enzyme assays
J. Sep. Sci. 28 1658-1665 (2005)

Brivio, M.; Liesener, A.; Oosterbroek, R.E.; Verboom, W.; Karst, U.; van den Berg, A.; Reinhoudt, D.N.
Chip-based on-line nanospray MS method enabling study of the kinetics of isocyanate derivatization reactions
Anal. Chem. 77 6852-6856 (2005)

Hempen, C.; Van Leeuwen, S.M.; Luftmann, H.; Karst, U.
Liquid chromatographic/mass spectrometric investigation on the reaction products in the peroxidase-catalyzed oxidation of o-phenylenediamine by hydrogen peroxide
Anal. Bioanal. Chem. 382 234-238 (2005)

Blankert, B.; Hayen, H.; Van Leeuwen, S.M.; Karst, U.; Bodoki, E.; Lotrean, S.; Sandulescu, R.; Mora Diaz, N.; Dominguez, O.; Arcos, J.; Kauffmann, J.M.
Electrochemical, chemical and enzymatic oxidations of phenothiazines
Electroanalysis 17 1501-1510 (2005)

Van Leeuwen, S.M.; Blankert, B.; Kauffmann, J.-M.; Karst, U.
Prediction of clozapine metabolism by on-line electrochemistry/liquid chromatography/mass spectrometry
Anal. Bioanal. Chem. 382 742-750 (2005)

Falvey, P.; Lim, C.W.; Darcy, R.; Revermann, T.; Karst, U.; Giesbers, M.; Marcelis, A.T.M.; Lazar, A.; Coleman, A.W.; Reinhoudt, D.N.; Ravoo, B.J.
Bilayer vesicles of amphiphilic cyclodextrins: host membranes that recognize guest molecules
Chem. Eur. J. 11 1171-1180 (2005)

Liesener, A.; Karst, U.
Assessing protease activity pattern by means of multiple-substrate ESI-MS assays
Analyst 130 850-854 (2005)

Seiwert, B.; Henneken, H.; Karst, U.
Ferrocenoyl piperazide as derivatizing agent for the analysis of isocyanates and related compounds using liquid chromatography/electrochemistry/mass spectrometry (LC/EC/MS)
J. Amer. Soc. Mass Spectrom. 15 1727-1736 (2004)

Van Leeuwen, S.M., Hendriksen, L.; Karst, U.
Determination of aldehydes and ketones using derivatization with 2,4-dinitrophenylhydrazine (DNPH) and liquid chromatography/atmospheric pressure photoionization-mass spectrometry (LC/APPI-MS)
J. Chromatogr. A 1058 107-112 (2004)

Steinkamp, T.; Karst, U.
Detection scheme for bioassays based on 2,6-pyridinedicarboxylic acid derivatives and enzyme-amplified lanthanide luminescence
Anal. Chim. Acta 526 27-34 (2004)

Hempen, C.; Karst, U.
A dual fluorophore system for simultaneous bioassays
Anal. Chim. Acta 521 117-122 (2004)

Hayen, H.; Deschamps, A.A.; Grijpma, D.W.; Feijen, J.; Karst, U.
LC/MS studies on the in vitro degradation of a poly(ether ester) block copolymer
J. Chromatogr. A 1029 29-36 (2004)

Hayen, H.; Álvarez-Grima, M.M.; Debnath, S.C.; Noordermeer, J.W.M.; Karst, U.
Liquid chromatography/coordination ionspray-mass spectrometry (LC/CIS-MS) for the analysis of rubber vulcanization products
Anal. Chem. 76 1063-1068 (2004)

Diehl, G.; Wasinski, F.A.H.; Roberz, B.; Luftmann, H.; Schmidt, T.C.; Andersson, J.T.;
Karst, U.
Liquid chromatography/electrochemistry/mass spectrometry as screening technique for alcohols and phenols in fuels
Microchim. Acta 146 137-147 (2004)

Steinkamp, T.; Liesener, A.; Karst, U.
Reaction monitoring of enzyme-catalyzed ester cleavage by time resolved fluorescence spectroscopy and electrospray mass spectrometry - method development and comparison
Anal. Bioanal. Chem. 378 1124-1128 (2004)

Van Leeuwen, S.M.; Hayen, H.; Karst, U.
Liquid chromatography/electrochemistry/mass spectrometry of polycyclic aromatic hydrocarbons
Anal. Bioanal. Chem. 378 917-925 (2004)

Deschamps, A.A.; van Apeldoorn, A.A.; Hayen, H.; de Bruijn, J.D.; Karst, U.; Grijpma, D.W., Feijen, J.
In vivo and in vitro degradation of poly(ether ester) block copolymers based on poly(ethylene glycol) and poly (butylene terephthalate)
Biomaterials 25 247-258 (2004)

Hayen, H.; Jachmann, N.; Vogel, M.; Karst, U.
LC-electron capture-APCI(-)-MS determination of nitrobenzoxadiazole derivatives
Analyst 128 1365-1372 (2003)

Hayen, H.; Karst, U.
Analysis of phenothiazine and its derivatives using LC/electrochemistry/MS and LC/electrochemistry/fluorescence
Anal. Chem. 75 4833-4840 (2003)

Schulte-Ladbeck, R.; Karst, U.
Determination of triacetonetriperoxide in ambient air
Anal. Chim. Acta 482 183-188 (2003)

Steinkamp, T.; Schweppe, F.; Krebs, B.; Karst, U.
A tripod ligand as new sensitiser for the enzyme amplified lanthanide luminescence determination of esterase
Analyst 128 29-31 (2003)

Schulte-Ladbeck, R.; Karst, U.
Liquid chromatography - post-column photochemical conversion and electrochemical detection for determination of peroxide-based explosives
Chromatographia 57 S-61-S-65 (2003)

Henneken, H.; Lindahl, R.; Östin, A.; Vogel, M.; Levin, J.-O.; Karst, U.
Diffusive sampling of methyl isocyanate using 4-nitro-7-piperazino-benzo-2-oxa-1,3-diazole (NBDPZ) as derivatizing agent
J. Environ. Monit. 5 100-105 (2003)

Meyer, J.; Liesener, A.; Götz, S.; Hayen, H.; Karst, U.
Liquid chromatography with on-line electrochemical derivatization and fluorescence detection for the determination of phenols
Anal. Chem. 75 922-926 (2003)

Schulte-Ladbeck, R.; Kolla, P.; Karst, U.
Trace analysis of peroxide-based explosives
Anal. Chem. 75 731-735 (2003)

Vogel, M.; Karst, U.
4-Nitro-7-piperazino-benzo-2-oxa-1,3-diazole as a reagent for monitoring of airborne isocyanates by liquid chromatography
Anal. Chem. 74 6418-6426 (2002)

51. Harms, D.; Luftmann, H.; Müller, F.K.; Krebs, B.; Karst, U.
Selective determination of hydrogen peroxide by adduct formation with a dinuclear iron(III) complex and flow injection analysis / tandem mass spectrometry
Analyst 127 1410-1412 (2002)

Schulte-Ladbeck, R.; Kolla, P.; Karst, U.
A field test for the detection of peroxide-based explosives
Analyst 127 1152-1154 (2002)

Hayen, H.; Jachmann, N.; Vogel, M.; Karst, U.
LC/electron capture APCI-MS for the determination of nitroaromatic compounds
Analyst 127 1027-1030 (2002)

Diehl, G.; Karst, U.
Fast liquid chromatography/electrochemistry/mass spectrometry of ferrocenecarboxylic acid esters
J. Chromatogr. A 974 103-109 (2002)

Kempter, C.; Berkhoudt, T.W.; Greve Tolbøl, C.; Egmose, K.N.; Karst, U.
Air monitoring of aldehydes based on hydrazine reagents with triazine backbone
Anal. Bioanal. Chem. 372 639-643 (2002)

Schulte-Ladbeck, R.; Lindahl, R.; Levin, J.-O.; Karst, U.
Characterization of chemical interferences in the determination of unsaturated aldehydes using aromatic hydrazine reagents and liquid chromatography
J. Environ. Monit. 3 306-310 (2001)

Diehl, G.; Liesener, A.; Karst, U.
Liquid chromatography with post-column electrochemical treatment and mass spectrometric detection of non-polar compounds
Analyst 126 288-290 (2001)

Meyer, J.; Karst, U.
HPLC determination of paracetamol (acetaminophen) with post-column enzymatic derivatization and fluorescence detection
Chromatographia 54 163-167 (2001)

Meyer, J.; Karst, U.
Enzyme-linked immunosorbent assays based on peroxidase labels and enzyme amplified lanthanide luminescence detection
Analyst 126 175-178 (2001)

Jachmann, N.; Karst, U.
Synthesis and application of 4-(N,N-Dimethylaminosulfonyl)-7-N-methylhydrazino-2,1,3-benzooxadiazole (MDBDH) as new derivatizing agent for aldehydes
Fresenius´ J. Anal. Chem. 369 47-53 (2001)

Meyer, J.; Karst, U.
Peroxidase enhanced lanthanide luminescence - a new technique for the evaluation of bioassays
Analyst 125 1537-1538 (2000)

Diehl, G.; Karst, U.
Post-column oxidative derivatization for the liquid chromatographic determination of phenothiazines
J. Chromatogr. A 890 281-287 (2000)

Vogel, M.; Pötter, W.; Karst, U.
Characterization of a chemical artifact in the liquid chromatographic determination of
3-butyn-2-one using the 2,4-dinitrophenylhydrazine method
J. Chromatogr. A 886 303-307 (2000)

Meyer, J.; Büldt, A.; Vogel, M.; Karst, U.
4-(N-Methylhydrazino)-7-nitro-2,1,3-benzooxadiazole (MNBDH): A novel fluorogenic peroxidase substrate
Angew. Chem. 112 1510-1512 (2000), Angew. Chem. Int. Ed. 39 1453-1455 (2000)

Kempter, C.; Karst, U.
Determination of carbonyl compounds in waters using triazine-based hydrazine reagents and liquid chromatography
Analyst 125 433-438 (2000)

Zurek, G.; Büldt, A.; Karst, U.
Determination of acetaldehyde in tobacco smoke using N-methyl-4-hydrazino-7-nitrobenzo-
furazan and liquid chromatography/mass spectrometry
Fresenius´ J. Anal. Chem. 366 396-399 (2000)

Zurek, G.; Karst, U.
2,4-Dinitro-3,5,6-trideuterophenylhydrazones for the quantification of aldehydes and ketones in air samples by HPLC/APCI-MS
J. Chromatogr. A 869 251-259 (2000)

Effkemann, S.; Brødsgaard, S.; Mortensen, P.; Linde, S.-A.; Karst, U.
Spectrophotometric and direct-reading methods for the analysis of gas phase peroxyacetic acid
Fresenius´ J. Anal. Chem. 366 361-364 (2000)

Kempter, C.; Pötter, W.; Binding, N.; Kläning, H.; Witting, U.; Karst, U.
Tailor-made derivatizing agents for carbonyl compounds using liquid chromatography
Anal. Chim. Acta 410 47-64 (2000)

Zurek, G.; Karst, U.
Liquid chromatography/mass spectrometry method for the determination of aldehydes derivatized by the Hantzsch reaction
J. Chromatogr. A 864 191-197 (1999)

Kempter, C.; Zurek, G.; Karst, U.
Determination of carbonyls using liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization
J. Environ. Monit. 1 307-311 (1999)

Meyer, J.; Karst, U.
Workplace monitoring of gas phase hydrogen peroxide by means of fluorescence spectroscopy
Anal. Chim. Acta 401 191-196 (1999)

Effkemann, S.; Brødsgaard, S.; Mortensen, P.; Linde, S.-A.; Karst, U.
Determination of gas phase peroxyacetic acid using pre-column derivatization with organic sulfide reagents and liquid chromatography
J. Chromatogr. A 855 551-561 (1999)

Zurek, G.; Luftmann, H.; Karst, U.
HPLC/APCI-MS with calibration based on stable isotope-labelled internal standards for the quantification of carbonyls in air samples
Analyst 124 1291-1295 (1999)

Harms, D.; Meyer, J.; Westerheide, L.; Krebs, B.; Karst, U.
Determination of glucose in soft drinks using its enzymatic oxidation and the detection of formed hydrogen peroxide with a dinuclear iron(III) complex
Anal. Chim. Acta 401 83-90 (1999)

Büldt, A.; Karst, U.
Determination of nitrite in waters by microplate fluorescence spectroscopy and HPLC with fluorescence detection
Anal. Chem. 71 3003-3007 (1999)

Sievers, R.E.; Karst, U.; Milewski, P.D.; Sellers, S.P.; Miles, B.A.; Schaefer, J.D.; Stoldt, C.R.; Xu, C.Y.
Formation of aqueous small droplet aerosols assisted by supercritical carbon dioxide
Aerosol Sci. Technol. 30 3-15 (1999)

Harms, D.; Karst, U.
Rapid and selective determination of peroxyacetic acid in disinfectants using flow injection analysis
Anal. Chim. Acta 389 233-238 (1999)

Kempter, C.; Büldt, A.; Karst, U.
Workplace monitoring of oximes using 2,4-dinitrophenylhydrazine-coated silica gel cartridges and liquid chromatography
Anal. Chim. Acta 388 181-186 (1999)

Büldt, A.; Lindahl, R.; Levin, J.; Karst, U.
A diffusive sampling device for the determination of formaldehyde in air using N-methyl-4- hydrazino-7-nitrobenzofurazan (MNBDH) as reagent
J. Environ. Monit. 1 39-43 (1999)

Harms, D.; Than, R.; Krebs, B.; Karst, U.
Flow injection analysis of hydrogen peroxide in disinfectants
Fresenius´ J. Anal. Chem. 364 184-188 (1999)

Büldt, A.; Karst, U.
N-Methyl-4-hydrazino-7-nitrobenzofurazan as a new reagent for air monitoring of aldehydes and ketones
Anal. Chem. 71 1893-1898 (1999)

Harms, D.; Than, R.; Pinkernell, U.; Schmidt, M.; Krebs, B.; Karst, U.
Selective determination of hydrogen peroxide in household products using its molecular recognition by a dinuclear iron(III) complex
Analyst 123 2323-2328 (1998)

Binding, N.; Kläning, H.; Karst, U.; Pötter, W.; Czeschinski, P.A.; Witting, U.
Analytical reliability of carbonyl compound determination using 1,5-dansylhydrazine- derivatization
Fresenius´ J. Anal. Chem. 362 270-273 (1998)

Effkemann, S.; Pinkernell, U.; Neumüller, R.; Schwan, F.; Engelhardt, H.; Karst, U.
Liquid chromatographic simultaneous determination of peroxycarboxylic acids using post column derivatization
Anal. Chem. 70 3857-3862 (1998)

Effkemann, S.; Karst, U.
Reagent for the high-performance liquid chromatography determination of peroxycarboxylic acids
Analyst 123 1761-1765 (1998)

Effkemann, S.; Pinkernell, U.; Karst, U.
Peroxide analysis in laundry detergents using liquid chromatography
Anal. Chim. Acta 363 97-103 (1998)

Pötter, W.; Lamotte, S.; Engelhardt, H.; Karst, U.
Non-porous silica for ultrafast reversed-phase HPLC separation of aldehyde and ketone 2,4-dinitrophenylhydrazones
J. Chromatogr. A 786 47-55 (1997)

Pinkernell, U.; Effkemann, S.; Karst, U.
Simultaneous HPLC determination of peroxyacetic acid and hydrogen peroxide
Anal. Chem. 69 3623-3627 (1997)

Zurek, G.; Karst, U.
Microplate photometric determination of aldehydes in disinfectant solutions
Anal. Chim. Acta 351 247-257 (1997)

Büldt, A.; Karst, U.
1-Methyl-1-(2,4-dinitrophenyl)hydrazine as a new reagent for the HPLC determination of aldehydes
Anal. Chem. 69 3617-3622 (1997)

Pinkernell, U.; Lüke, H.-J.; Karst, U.
Selective photometric determination of peroxycarboxylic acids in the presence of hydrogen peroxide
Analyst 122 567-571 (1997)

Sievers, R.E.; Karst, U.; Schaefer, J.D.; Stoldt, C.R.; Watkins, B.A.
Supercritical CO2-assisted nebulization for the production and administration of drugs
J. Aerosol. Sci. 27 S497-S498 (1996)

Pötter, W.; Karst, U.
Identification of chemical interferences in aldehyde and ketone determination using dual wavelength detection
Anal. Chem. 68 3354-3358 (1996)

Eulering, B.; Schmidt, M.; Pinkernell, U.; Karst, U.; Krebs, B.
Ein neuer unsymmetrischer dinuklearer Eisen(III)-Komplex mit Peroxidaseeigenschaften
Angew. Chem. 108 2102-2103 (1996), Angew. Chem. Int. Ed. 35 1973-1974 (1996)

Pinkernell, U.; Effkemann, S., Nitzsche, F.; Karst, U.
Rapid high-performance liquid chromatographic method for the determination of peroxyacetic acid
J. Chromatogr. A 730 203-208 (1996)

Eulering, B.; Schmidt, M.; Pinkernell, U.; Karst, U.; Krebs, B.
A new unsymmetrical model compound for the uteroferrin-arsenato complex and oxidation of different substrates by diferric peroxo complexes
J. Inorg. Biochem. 59 403 (1995)

Buhr, S.M.; Buhr, M.P.; Fehsenfeld, F.C.; Holloway, J.S.; Karst, U.; Norton, R.B.; Parrish, D.; Sievers, R.E.
Development of a semi-continuous method for the measurement of nitric acid vapor and particulate nitrate and sulfate
Atmos. Environ. 29 2609-2624 (1995)

Pinkernell, U.; Karst, U.; Cammann, K.
Determination of peroxyacetic acid using high performance liquid chromatography with external calibration
Anal. Chem. 66 2599-2602 (1994)

Grömping, A.H.J.; Karst, U.; Cammann, K.
Development of a method for simultaneous determination of nitrogen oxides, aldehydes, and ketones in air samples
J. Chromatogr. A 653 341-347 (1993)

Karst, U.; Binding, N.; Cammann, K.; Witting, U.
Interferences of nitrogen dioxide in the determination of aldehydes and ketones by sampling on 2,4-dinitrophenylhydrazine-coated solid sorbent
Fresenius' J. Anal. Chem. 345 48-52 (1993)


Reviews, Book Chapters, Misc. Publications


Künnemeyer, J.; Karst, U.
Microchip capillary electrophoresis for quantitative analysis - a practical approach to overcome current limitations
GIT Special Separation, in press (2008)

Schebb, N.H.; Vogel, M.; Karst, U.; Kool, J.; Irth, H. HPLC mit biochemischer Detektion (BCD) GIT Laborfachzeitschrift 52 365-368 (2008)

Lohmann, W.; Karst, U.
Biomimetic modeling of oxidative drug metabolism - strategies, advantages and limitations
Anal. Bioanal. Chem. 391 79-96 (2008)

Van Leeuwen, S.M.; Tan, B.; Grijpma, D.W.; Feijen, J.; Karst, U.
Characterization of synthetic block copolymers by LC-MS
Am. Lab. 40 36-39 (2008)

Revermann, T.; Götz, S.; Künnemeyer, J.; Karst, U.
Quantitative analysis by microchip capillary electrophoresis - current limitations and problem solving strategies
Analyst 132 167-174 (2008)

Seiwert, B.; Karst, U.
Ferrocene-based derivatization in analytical chemistry
Anal. Bioanal. Chem. 390 181-200 (2008)

Vogel, M.; Karst, U.
Aus der Probe ins Massenspektrometer
Nachr. Chem. 55 420-424 (2007)

Henneken, H.; Vogel, M.; Karst, U.
Determination of airborne isocyanates
Anal. Bioanal. Chem. 387 219-236 (2007)

Götz, S.; Karst, U.
Recent developments in optical detection methods for microchip separations
Anal. Bioanal. Chem. 387 183-192 (2007)

Vogel, M.; Scheffer, A.; Liesener, A.; Karst, U.
Laser desorption assays - MALDI-MS, DIOS-MS, and SAMDI-MS
in: K. Wanner, G. Höfner (Eds.), Mass Spectrometry in Medicinal Chemistry, S. 285-301,
Wiley-VCH, Weinheim (2007)

Götz, S.; Scheffer, A.; Vogel, M.; Karst, U.
A pleading for chromatography
G.I.T. Laboratory Journal 6/2006 22-23 (2006)

Karst, U.; Liesener, A.; Vogel, M.
Kontrolle von Bioassays durch Massenspektrometrie
LaborPraxis 11/2006 22-24 (2006)

Schulte-Ladbeck, R.; Vogel, M.; Karst, U
Recent methods for the determination of peroxide-based explosives
Anal. Bioanal. Chem. 386 559-565 (2006)

Karst, U.
Where the worlds of nanotechnology, materials science, and bioanalysis converge
Anal. Bioanal. Chem. 384 559 (2006)

Bos, S.J.; Van Leeuwen, S.M.; Karst, U.
From fundamentals to applications: recent developments of atmospheric pressure photoionization mass spectrometry
Anal. Bioanal. Chem. 384 85-99 (2006)

Hempen, C.; Karst, U.
Labeling strategies for bioassays
Anal. Bioanal. Chem. 384 572-583 (2006)

Vogel, M.; van Leeuwen, S.; Seiwert, B.; Karst, U.
Analytik unpolarer Verbindungen mittels LC/Elektrochemie/MS
Nachr. Chem. 53 1145-1147 (2005)

Karst, U.
Liquid chromatography/electron capture-atmospheric pressure chemical ionization mass spectrometry
Anal. Bioanal. Chem. 382 1744-1746 (2005)

Liesener, A.; Karst, U.
Monitoring enzymatic conversions by mass spectrometry - a critical review
Anal. Bioanal. Chem. 382 1451-1464 (2005)

Steinkamp, T.; Karst, U.
Detection strategies for bioassays based on luminescent lanthanide complexes and signal amplification
Anal. Bioanal. Chem. 380 24-30 (2004)

Karst, U.; Götz, S.
Trends in der Analytik
Analytica Pro 8-10 (2004)

Karst, U.
Liquid chromatography mass spectrometry: reaching maturity rapidly
Anal. Bioanal. Chem. 378 841 (2004)

Liesener, A.; Steinkamp, T.; Karst, U.
Massenspektrometrische Detektion in Bioassays - Herausforderungen und Chancen
GIT Laborfachzeitschrift 48 454-457 (2004)

Karst, U.
Electrochemistry/mass spectrometry (EC/MS) - a new tool to study drug metabolism and reaction mechanisms
Angew. Chem. Int. Edit. 43 2476-2478 (2004), Angew. Chem. 116 2530-2532 (2004)

Hayen, H.; Karst, U.
Elektroneneinfang-Ionisierung in der LC/MS
GIT Laborfachzeitschrift 48 30-33 (2004)

Vogel. M.; Karst, U.
Nitrobenzoxadiazol-Reagenzien in der Umwelt- und Bioanalytik
Chem. Lab. Biotechn. 54 288-291 (2003)

Hayen, H., Vogel, M.; Karst, U.
Recent developments in the determination of formaldehyde in air samples using derivatizing agents
Gefahrst.-Reinhalt. Luft 63 295-298 (2003)

Henneken, H.; Vogel, M.; Karst, U.
Derivatisierungstechniken zur Bestimmung von Isocyanaten in Luftproben
GIT Laborfachzeitschrift 47 647-649 (2003)

Hayen, H.; Karst, U.
Strategies for the LC/MS analysis of non-polar compounds
J. Chromatogr. A 1000 549-565 (2003)

Hayen, H.; van Leeuwen, S.; Zurek, G.; Karst, U.
HPLC/MS für die Analytik unpolarer Verbindungen
GIT Separation 22 52-54 (2002)

Diehl, G.; Karst, U.
On-line electrochemistry/MS and related techniques
Anal. Bioanal. Chem. 373 390-398 (2002)

Karst, U.
Detection techniques for liquid chromatography
Anal. Bioanal. Chem. 372 27-28 (2002)

Karst, U.
Selektiv und nachweisstark: Fluoreszenzdetektion in der HPLC
LaborPraxis Sonderheft Labfuture 94-95 (2001)

Meyer, J.; Karst, U.
Enzyme Amplified Lanthanide Luminescence (EALL) – ein leuchtendes Beispiel für moderne Detektionsverfahren in der Bioanalytik
GIT Laborfachzeitschrift 45 721-723 (2001)

Diehl, G.; Karst, U.
Flüssigchromatographie/Elektrochemie/Massenspektrometrie (HPLC/EC/MS): Eine Kopplungstechnik mit Potential
GIT Laborfachzeitschrift 45 376-379 (2001)

Vogel, M.; Büldt, A.; Karst, U.
Hydrazine reagents as derivatizing agents in environmental analysis - a critical review
Fresenius´ J. Anal. Chem. 366 781-791 (2000)

Jachmann, N.; Büldt, A.; Karst, U.
N-alkylierte Hydrazinreagenzien in der Umweltanalytik
GIT Laborfachzeitschrift 43 926-929 (1999)

Effkemann, S.; Pinkernell, U.; Harms, D., Karst, U.
Recent techniques for the determination of peroxycarboxylic acids
International Laboratory 29(7) 14-19 (1999)

Meyer, J.; Karst, U.
Zeitverzögerte Fluoreszenzspektroskopie mit Lanthanoidkomplexen - Prinzipien und Anwendungen
Nachr. Chem. Tech. Lab. 47 1116-1119 (1999)

Effkemann, S.; Harms, D.; Pinkernell, U.; Karst, U.
Selektive Verfahren zur Bestimmung von Peroxycarbonsäuren
GIT Laborfachzeitschrift 43 380-384 (1999)

Xu, C.Y.; Sievers, R.E.; Karst, U.; Watkins, B.A.; Karbiwnyk, C.M.; Andersen, W.C.; Schaefer, J.D.; Stoldt, C.R.
Supercritical carbon dioxide assisted aerosolization for thin film deposition, fine powder generation, and drug delivery
in: P.T. Anastas; T.C. Williamson (Hrsg.), Green Chemistry, S. 312-335, Oxford University Press, Oxford (1998)

Pinkernell, U.; Karst, U.; Nitzsche, F.; Tanzer, D.
Analytik von Peroxiden in Desinfektionsmitteln
Brauwelt 1256-1261 (1997)

Cammann, K.; Buschmann, N.; Dumschat, C.; Högg, G.; Karst, U.; Roß, B.
Chemosensoren - Ein kritischer Blick auf den heutigen Stand, Teil 1: Sensoren zur Messung in flüssiger Phase
Analytiker-Taschenbuch Bd. 15, S. 3-40, Springer-Verlag, Berlin, Heidelberg (1997)

Karst, U.
2,4-Dinitrophenylhydrazin als Derivatisierungsreagenz zur Bestimmung von Aldehyden und Ketonen
GIT Fachz. Labor 40 49-50 (1996)

Karst, U.; Grömping, A.H.J.; Binding, N.; Witting, U.; Cammann, K.
Determination of aldehydes, ketones, and nitrogen oxides in car exhaust
Am. Environ. Lab. 7(2) 32-33 (1995)

Cammann, K.; Warsinke, A.; Wortberg, M.; Middendorf, C.; Karst, U.; Renneberg, R.
FIA immunoassays with electrochemical and optical detection
NATO ASI Ser., Ser. E 252 415-419 (1993)

Karst, U.; Krause, J.; Meyer, H.; Wortberg, M.; Cammann, K.
Labor 2000 62-68 (1992)




Cammann, K.; Grömping, A.; Karst, U.
Verfahren zur Bestimmung der Konzentration von Stickoxiden in Gasen, die auch Aldehyde und Ketone enthalten können
DE 41 06 875.0 (1991)

Karst, U.; Sievers, R.E. (Anmelder: University Technology Corporation, Boulder, CO, U.S.A.)
Method and apparatus for fine particle formation
US 5,639,441 (1994)

Büldt, A.; Karst, U.
Verfahren zur Analytik von Aldehyden, Ketonen, Stickstoffdioxid oder Ozon in flüssigen oder gasförmigen Proben
DE 196 11 657.0 (1996)

Pötter, W.; Karst, U.; Binding, N.; Kläning, H.
Derivatisierungsreagenz zur Bestimmung von Aldehyden, Ketonen oder Isocyanaten in flüssigen oder gasförmigen Proben
DE 197 10 277.8 (1997)

Sievers, R.E.; Karst, U. (Anmelder: University Technology Corporation, Boulder, CO, U.S.A.)
Method and apparatus for fine particle formation
US 6,095,134 (1997)

Büldt, A.; Karst, U.
Neue Benzooxadiazole
DE 198 00 537.7 (1998)

Büldt, A.; Kempter, C.; Karst, U.
Verfahren zur Bestimmung von Oximen
DE 198 00 543.1 (1998)

Effkemann, S.; Karst, U.
Reagenz und Verfahren zur Bestimmung von Peroxycarbonsäuren
DE 198 07 667.3 (1998)

Meyer, J.; Karst, U.
Verfahren zur Bestimmung von Peroxiden
DE 198 13 247.6 (1998)

Meyer, J.; Jachmann, N.; Büldt, A.; Karst, U.
Verfahren zur Bestimmung von Wasserstoffperoxid und Hydroperoxiden
DE 199 32 380.1 (1999)

Vogel, M.; Karst, U.
Verfahren zur Bestimmung von Isocyanaten
DE 199 36 731.0 (1999)

Steinkamp, T.; Schweppe, F.; Karst, U.; Krebs, B.
Verfahren zur Bestimmung hydrolytischer Enzyme
DE Anmeldung 101 02 839.3 (2001)

Hayen, H.; Jachmann, N.; Vogel, M.; Karst, U.
Verfahren zur massenspektrometrischen Bestimmung organischer Verbindungen
DE Anmeldung 101 23 460.0 (2001)

Diehl, G.; Hayen, H.; Karst, U. (Anmelder: ESA Inc., Chelmsford, MA, U.S.A.)
Coupling electrochemistry to electrospray ionization and APCI mass spectrometry
U.S. Patent provisional application 60/323552 (2001)



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